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3081
Early Dynamics of Circulating Tumor DNA Following Curative Hypofractionated Radiotherapy Related to Disease Control in Lung Cancer
Published 2025-05-01“…The Dmax showed better disease control rate with marginal significance (<i>p</i> = 0.081). …”
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3082
Breaking barriers: targeted delivery of resveratrol in lung cancer using folate-integrated and pH-responsive hybrid nanocarriers
Published 2025-07-01“…Finally, in vivo targeting and anticancer studies demonstrated that FOL-RSV-LPHNCs selectively internalized to the cancerous region and suppressed the tumor volume with an 8.66-fold higher rate in the xenograft mouse model. The folate receptor-mediated uptake mainly facilitates this superior therapeutic response which was further confirmed by in silico molecular docking and dynamic simulation. …”
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3083
Physiological insights into the responses of tea plants to aluminum through an integrated transcriptomic and metabolomic analysis
Published 2025-07-01“…Compared to 0 mM Al treatment, low Al concentrations (0.4 mM) enhanced root vitality by 8.91%, while higher Al concentrations (10 and 100 mM) reduced root vigor by 19.31% and 76.81%, respectively. In a similar pattern, the electron transfer rate in leaves remained stable under low Al levels but significantly decreased under high Al conditions. …”
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3084
Impact of Malaria Diagnostic Technologies on the Disease Burden in the Sub-Saharan Africa
Published 2022-01-01“…However, in certain areas, the rate of decline has slowed or even reversed the gains made so far. …”
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3085
Identification of endothelial INSR as an osteosarcoma-related biomarker and therapeutic target based on weighted gene co-expression network analysis
Published 2025-08-01“…Abstract Background Osteosarcoma (OS) is the most common primary malignant bone tumor characterized by a high rate of metastasis. The clinical efficacy of current targeted drugs for OS is limited, highlighting the urgent need to identify novel therapeutic targets. …”
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3086
Dr Papineau Meets Dr Masquelet—Management of Open Calcaneal Fractures, Combining Two Techniques: A Case Report
Published 2025-06-01“…Aim and background: Open fractures of the calcaneum are often the source of significant morbidity due to the high rate of wound infection and significant morbidity, ranging from malunion to amputation. …”
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3087
Fluid–solid coupling productivity analysis of multi-stage fractured horizontal wells in shale reservoirs
Published 2025-05-01“…The simulation results of the model align with actual field data, showing that gas production follows an “L-shaped” decline pattern with a coincidence rate exceeding 70%, verifying the model’s accuracy.…”
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3088
Safety and efficacy of prone position ventilation in patients with severe pneumonia in neurosurgical intensive care units
Published 2025-08-01“…Changes in blood gas analysis[pH,arterial partial pressure of oxygen(PaO2),arterial partial pressure of carbon dioxide(PaCO2),oxygenation index]and hemodynamics[heart rate(HR),mean arterial pressure(MAP)]were compared before prone positioning,and at 1 day,3 days,5 days,and 7 days after resuming supine position following prone position treatment. …”
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3089
Clinical characteristics and outcomes of non-tuberculous mycobacterial pulmonary infections after hematopoietic stem cell transplantation: A retrospective cohort study
Published 2025-07-01“…Conclusion: Outcomes vary significantly among non-tuberculous mycobacterial pulmonary infections based on mycobacterial species, rate of colonization and degree of immunosuppression. …”
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3090
Cutis verticis gyrata in a Patient with Familial presenile sebaceous hyperplasia Presenting as &ldquo;Leonine facies&rdquo;: A Rare Case
Published 2025-06-01“…Isotretinoin, with its sebocyte-suppressing effect, may reduce gland size but has a high recurrence rate upon discontinuation. Early recognition and a multidisciplinary approach are crucial to prevent further progression, particularly in older patients.Keywords: cutis verticis gyrata, familial presenile sebaceous hyperplasia, leonine facies…”
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3091
Isokinetic knee strength as a predictor of cardiorespiratory responses during loaded aerobic capacity test in elite athletes
Published 2025-07-01“…Cardiorespiratory parameters—average breath volume (ABV), average breath frequency (ABF), auxiliary oxygen density (AOD), and heart rate (HR)—were recorded during the Bruce Protocol conducted under two conditions: unloaded and with a 10 kg loaded vest. …”
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3092
Energy Dissipation and Failure Characteristics of Layered Composite Rocks under Impact Load
Published 2021-01-01“…The energy dissipation pattern of composite rock had an obvious strain rate effect. …”
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3093
Neuroendocrine tumors of the digestive system: pathologic and molecular characteristics
Published 2015-06-01“…The grade (G) is based on the proliferative activity of the tumor assessed by the mitotic rate or by Ki-67 immunohistochemistry. Several markers are useful in the identification of a primary organ of NETs in metastatic lesions are also discussed. …”
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3094
Network meta-analysis of erlotinib, gefitinib, afatinib and icotinib in patients with advanced non-small-cell lung cancer harboring EGFR mutations.
Published 2014-01-01“…Pooled data on objective response rate (ORR), progression free survival (PFS), overall survival (OS) were calculated. …”
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3095
Demographic and clinical characteristics of patients with benign bone tumors: Evidence of bimodal age distribution in a Hispanic population
Published 2025-08-01“…This indicates an incidence rate of 0.00018 per person-year. The average age was 38.8 years (SD 24.0), with females representing 58 % of the sample. …”
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3096
Reduced Inter-Element Interference mmWave MIMO Antenna and Its Application in WBAN
Published 2025-01-01“…A specific absorption rate (SAR) analysis confirmed that the design complies with safety standards for both 1g and 10g tissue models. …”
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3097
Early Recurrence of Hepatocellular Carcinoma in Patients without Microscopic Vascular Invasion: Clinicopathological Characteristics and Risk Factors
Published 2025-06-01“…Microscopic features of both tumor and non-tumor liver tissue were assessed using Hematoxylin-Eosin-stained slides.Results: The majority of patients were male (78.3%) and had cirrhosis (72.5%). The early recurrence rate was 31.9%, with most recurrences occurring between 6- and 18-month post-surgery. …”
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3098
Factors associated with interstitial lung disease in patients with rheumatoid arthritis
Published 2024-09-01“…Patients exhibited low disease activity [mean Disease Activity Score 28-erythrocyte sedimentation rate score (SD) 2.69 (0.90)] and mild functional impairment [median Health Assessment Questionnaire score (range) 0.25 (0–0.63)]. …”
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3099
Comparative analysis of START and CAVI arterial stiffness scores in hypertensive patients
Published 2023-04-01“…Parameters were associated with age (r=0,412 for CAVI and r=0,355 for START; p<0,001), smoking duration (r=0,390 and r=0,361; p<0,001), glomerular filtration rate (r=-0,317 and r= -0,318; p<0,001), body mass index (r=-0,176 and r=-0,185; p=0,001). …”
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3100
RNAi-mediated suppression of toll-like receptor NlToll1 enhances Nilaparvata lugens susceptibility to entomopathogenic fungal infection
Published 2025-06-01“…Toll-like receptors (TLRs) are a family of crucial pattern recognition proteins that are responsible for the immunologic recognition of invading pathogen in insects. …”
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