Effect of Different Media and Plant Hormone Concentrations on Callus Induction and Regeneration of Red Squill (<i>Squilla maura</i>) and Peruvian Squill (<i>Oncostema peruviana</i>... by Ibtisam Chakrane, Omar Chlyah, Said Boughribil, Fatima Gaboun, Meriem Mdarhri Alaoui

“…All treatments resulted in callogenesis rates between 65–100% for both species. These treatments led to direct bulbil regeneration. …”
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Does Seasonality Affect Peptic Ulcer Perforation? A Single-Center Retrospective Study by Iva Krajnović, Zenon Pogorelić, Iva Perić, Marija Ćavar, Matija Borić

“…Previous studies have suggested a seasonal pattern in the occurrence of symptomatic perforated peptic ulcers. …”
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Development technologies and models of different types of gas reservoirs in Ordos Basin, NW China by Ailin JIA, Dewei MENG, Guoting WANG, Guang JI, Zhi GUO, Naichao FENG, Ruohan LIU, Suqi HUANG, Shuai ZHENG, Tong XU

“…Four key directions of future research and technological breakthroughs are proposed: (1) Utilizing dual-porosity (fracture-matrix) modeling techniques in low-permeability carbonate reservoirs to delineate the volume and distribution of remaining gas in secondary pay zones, supporting well pattern optimization and production enhancement of existing wells. (2) Integrating well-log and seismic data to characterize reservoir spatial distribution of successive strata, enhancing drilling success rates in low-permeability sandstone reservoirs. (3) Utilizing the advantages of horizontal wells to penetrate effective reservoirs laterally, achieving meter-scale quantification of small-scale single sand bodies in tight gas reservoirs, and applying high-resolution 3D geological models to clarify the distribution of remaining gas and guide well placement optimization. (4) Further strengthening the evaluation of deep coal-rock gas in terms of resource potential, well type and pattern, reservoir stimulation, single-well performance, and economic viability.…”
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Burden of six common sexually transmitted infections groups in North Africa and Middle East Region from 1990 to 2021: A systematic analysis of global burden of diseases by Amirhossein Shahsavand, Leonardo Oliveira Reis, Ali Golestani, Alireza Namazi Shabestari, Ziba Aghsaeifard, Ozra Tabatabaei-Malazy, Iman Menbari Oskouie, Bagher Larijani, Seyed Mohammad Kazem Aghamir

“…Both age-standardized rates (ASRs) and total numbers were evaluated across 21 NAME countries, with breakdowns by sex, age, and sociodemographic index (SDI). …”
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Postoperative liver dysfunction in gastric cancer patients following early enhanced nutritional protocols: a retrospective observational study by Kazuo Kobayashi, Satoshi Ida, Masanari Tsuji, Arisa Nawa, Takeshi Aoyama, Takashi Yokokawa, Yoshikazu Tateai, Shuichi Watabe, Hisanori Shimizu, Souya Nunobe, Masakazu Yamaguchi

“…AST and ALT levels showed a biphasic pattern, with two distinct peaks observed on POD 1 and POD 7. …”
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Understanding the etiology of diarrheal illness in Cambodia in a case-control study from 2020 to 2023 by Paksathorn Kietsiri, Siriporn Sornsakrin, Samon Nou, Wilawan Oransathid, Dutsadee Peerapongpaisarn, Wirote Oransathid, Panida Nobthai, Patcharawalai Wassanarungroj, Siriphan Gonwong, Pimmada Sakpaisal, Nuanpan Khemnu, Somethy Sok, Sokh Vannara, Chiek Sivhour, Sidonn Krang, Ly Sovann, Em Sovannarith, Woradee Lurchachaiwong, Sidhartha Chaudhury, Nattaya Ruamsap, Paphavee Lertsethtakarn

“…Bacterial isolates were tested for antibiotic resistance patterns. From enrolled diarrhea cases, 533 stool samples (58%) were positive for enteric pathogens, compared to 389 samples (49%) in controls, underscoring the high carriage rate of enteric pathogens in this population as well as the difficulties in establishing the etiology of diarrhea cases. …”
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Trends in prescription opioid use in Europe: A DARWIN EU® multinational cohort study including seven European countries by Junqing Xie, Mike Du, Yuchen Guo, Cesar Barboza, James T. Brash, Antonella Delmestri, Talita Duarte-Salles, Talita Duarte-Salles, Jasmine Gratton, Romain Griffier, Raivo Kolde, Wai Yi Man, Núria Mercadé-Besora, Marek Oja, Sarah Seager, Katia Verhamme, Dina Vojinovic, Edward Burn, Daniel Prieto-Alhambra, Daniel Prieto-Alhambra, Martí Català, Annika M. Jödicke

“…More data are needed to monitor evolving opioid prescription patterns in Europe, particularly in the post-pandemic era.…”
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Characteristics of malaria vector populations and transmission before a randomised controlled trial assessing the efficacy of next-generation insecticide-treated nets in Côte d’Ivo... by Ludovic Phamien Ahoua Alou, Alphonsine Amanan Koffi, Edouard Dangbenon, Soromane Camara, Joseph Biggs, Marius Gonse Zoh, Serge Brice Assi, Colette Sih, Benoit Talbot, Manisha Ann Kulkarni, Louisa Alexandra Messenger, Natacha Protopopoff, Jackie Cook, Raphael N’Guessan

“…Plasmodium sporozoite infections were detected by qPCR to estimate infection rates. The entomological inoculation rate was calculated as the product of the mosquito biting rate and the sporozoite infection rate. …”
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High-risk HPV distribution and importance of continuing cervical cancer screening of women aged 65 years and older: a study based on 2 152 766 women in China by Bo Wu, Yu Jiang, Jiahui Wang, Xiaotian Li, He Wang, Fanghui Zhao, Zichen Ye, Yingyu Zhong, Shuyan Jin, Xuelian Zhao, Yueyun Wang

“…The hr-HPV prevalence in women aged≥65 was 13.67%, with a CIN2+ detection rate of 3.33‰ and a cancer rate of 0.92‰, compared with 8.08%, 1.55‰ and 0.1‰, respectively, in women aged&lt;65 (all p&lt;0.001). …”
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Barriers and facilitators to implementing a task-sharing mental health intervention for Sickle Cell Disease populations in low- and middle-income countries: a qualitative analysis... by John Patena, Leah Elster, Tania Hameed, Sumedha Kulkarni, Alden Yuanhong Lai, Annika C. Sweetland, Joyce Gyamfi, Temitope Ojo, Angela Odoms-Young, Charmaine Royal, Emmanuel Peprah

“…BackgroundPeople living with Sickle Cell Disease (SCD) experience higher rates of common mental disorders (CMD). There is an alarming treatment gap in the provision of adequate mental health services for CMDs in low- and middle-income countries (LMIC). …”
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Low dietary calcium intake leads to a higher colorectal cancer burden in countries with low social development: findings from the Global Burden of Disease Study 2021 by Junhong Wu, Ziyi Zhang, Jiong Chen, Shiya Yu, Donglin Liu, Junhui Jiang, Tingting Liu, Hu Zhao, Hu Zhao, Yu Wang, Yu Wang

“…Joinpoint regression analysis was conducted to assess temporal patterns in disease burden. Estimated annual percentage changes (EAPCs) were calculated to quantify the rate of change in relevant indicators. …”
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Multicenter study correlating molecular characteristics and clinical outcomes of cancer cases with patient-derived organoids by Paloma Navarro, Tatiana P. Grazioso, Arantzazu Barquín, Maria Barba, Mónica Yagüe, Carlos Millán, Irene López, Elena Sevillano, Miguel Quiralte, Paloma Fernández, Diego Losada, Eduardo Caleiras, Julia Calzas, Beatriz Jiménez, Sergio Ruiz-Llorente, Juan Justo, Félix Guerrero, Vital Hevia, Raquel Martín, Francisco José Pérez-Rodriguez, Julia Tejerina, Mario Prieto, Paula Comune, Juan Francisco Rodriguez-Moreno, Jesús García-Donás

“…PDOs reproduced pathological and immunohistochemical patterns of source tumors, with pathogenic variants confirmed in 84% (21/25). …”
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Thermo-hydro-mechanical coupling mechanisms and sensitivity analysis of abandoned mine thermal energy storage systems by Liyuan LIU, Yaohui LI, Tao WANG, Tongbin ZHAO, Qiang KOU, Zerui MI, Le ZHANG

“…A three-dimensional thermo-hydro-mechanical (THM) coupled numerical model is developed to calculate the coupled effects over a decade of system operation and analyze heat transfer processes along with stress variation patterns in the roadway’s surrounding rock. Results indicate that the MTES system effectively utilizes geothermal environments for high-efficiency storage of waste heat, achieving a residual temperature of 35.5 ℃ (44.4% retention rate) during the first year following the injection of 80 ℃ water, with winter extraction temperatures progressively increasing annually. …”
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Spatio-Temporal Characteristics and Driving Forces of Landscape Ecological Risks in Highly Urbanized Areas: A Case Study of Suzhou City by Lingyue LU, Dawei SHAO, Dianming WU

“…However, relatively little attention has been given to urbanized areas characterized by high rates of population growth and land development. …”
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A longitudinal qualitative study of clinical nurses caring for hospitalized adults during the first fifteen months of COVID-19: lessons in professional survival and leadership by Elizabeth M. Norman, Mildred Ortu Kowalski, Roxanne Sabatini, Carol S. Jones, Wendy Silverstein

“…The research team wondered how a large American suburban medical center staff was dealing with this virus and if there were changing patterns in the experiences and thoughts of clinical nurses as the virus evolved in 2020–2021. …”
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Dietary inflammatory index and mortality in middle-aged and elderly patients with metabolic syndrome by Xiangmei Li, Lei Liu, Xing Li, Long Yang, Li Men

“…Promoting an anti-inflammatory dietary pattern may be a cost-effective, non-pharmacologic approach to reducing the risk of cardiometabolic mortality in an aging population with a high cardiometabolic burden.…”
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Rapid biphasic decay of intact and defective HIV DNA reservoir during acute treated HIV disease by Alton Barbehenn, Lei Shi, Junzhe Shao, Rebecca Hoh, Heather M. Hartig, Vivian Pae, Sannidhi Sarvadhavabhatla, Sophia Donaire, Caroline Sheikhzadeh, Jeffrey Milush, Gregory M. Laird, Mignot Mathias, Kristen Ritter, Michael J. Peluso, Jeffrey Martin, Frederick Hecht, Christopher Pilcher, Stephanie E. Cohen, Susan Buchbinder, Diane Havlir, Monica Gandhi, Timothy J. Henrich, Hiroyu Hatano, Jingshen Wang, Steven G. Deeks, Sulggi A. Lee

“…Defective DNA had a similar biphasic pattern, but data were more variable. Predicted intact and defective decay rates were faster for PLWH with earlier timing of ART initiation, higher initial CD4 + T cell count, and lower pre-ART viral load. …”
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Real-World Evidence of Safety and Efficacy of Carboplatin plus Nanoparticle Albumin-Bound Paclitaxel in Patients with Advanced Non-Small-Cell Lung Cancer and Preexisting Interstiti... by Tomoyuki Araya, Toshiyuki Kita, Tsukasa Ueda, Nanao Terada, Tamami Sakai, Kenta Yamamura, Koji Kurokawa, Yuka Uchida, Takashi Sone, Hideharu Kimura, Kazuo Kasahara

“…The overall response and disease control rates were 77.8% (95% CI, 40.0–97.2) and 88.9% (95% CI, 51.8–97.2), respectively. …”
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Controlled-release fertilizer affects leaf nitrogen allocation and photosynthesis to improve nitrogen use efficiency and yield in the sunflower field by Wenhao Ren, Xianyue Li, Xianyue Li, Xianyue Li, Tingxi Liu, Tingxi Liu, Ning Chen, Maoxin Xin, Qian Qi, Bin Liu

“…Controlled-release fertilizers (CRF) have been reported to effectively reduce the nitrogen loss by matching the release pattern with crop N demand, thus increasing the yield. …”
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MtDNA copy number enrichment is associated with poor prognosis and eosinophilic morphology in clear cell renal cell carcinoma by Sarah Bellal, Sarah Bellal, Cyrielle Rolley, Jeremy Richard, Nolwenn Bounaix, Vincent Le Corre, Marie-Christine Copin, Odile Blanchet, Pierre Bigot, Pierre Bigot, Vincent Procaccio, Vincent Procaccio, Céline Bris, Céline Bris

“…CSS was significantly reduced in the “HIGH” than in the “LOW” group with respective 5-year survival rates: 78.7% (CI 95: 64.8–95.5) and 95.5% (CI 95 87.1–100.0) (Hazard Ratio: 7.4 (CI 95: 1.9–29.9, p = 0.027*) in multivariate analysis, including pathological classification, tumor size, International Society of Urological Pathology grade, lymphovascular invasion, dedifferentiated pattern, necrosis and adjuvant therapy. …”
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