Chemoprevention of 4NQO-Induced Mouse Tongue Carcinogenesis by AKT Inhibitor through the MMP-9/RhoC Signaling Pathway and Autophagy by Panpan Yin, Jiahui Chen, Yanlin Wu, Feng Gao, Jinlin Wen, Wenbin Zhang, Ying Su, Xinyan Zhang

“…Oral cancer (OC), the most common cancer in the head and neck, which has a poor prognosis, histopathologically follows a stepwise pattern of hyperplasia, dysplasia, and cancer. Blocking the progression of OC in the precancer stage could greatly improve the survival and cure rates. …”
Get full text

Pod Production Dynamics and Pod Size Distribution of Theobroma cacao L. Clone CCN 51 in Full Sunlight by Ramón E. Jaimez, Luigy Barragan, Miguel Fernández-Niño, Oswaldo J. Larreal B, Byron Flores

“…Fruit production varied following a seasonal pattern, reaching a maximum of 36 pods/tree, in trees cultivated in full sunlight, of which approximately 55% matured and were harvested. …”
Get full text

Integrated evaluation and optimization of acid fracturing effectiveness in carbonate reservoirs: Experimental insights and field validation. by Peng Lu, Songlei Li, Jinsong Liu, Nan Yuan, Heng Liu

“…Implementation of the proposed methodology has increased stimulation success rates from 55% to 82% in pilot fields, with sustained production gains exceeding 35%. …”
Get full text

Surveillance of Multidrug-Resistant Genes in Clinically Significant Gram-Negative Bacteria Isolated from Hospital Wastewater by Shriya C. Shetty, Lakshya S. Gowda, Ankeeta Menona Jacob, Kalidas Shetty, A. Veena Shetty

“…PCR confirmed the presence of drug-resistance genes in Gram-negative bacterial isolates. Results: High rates of <i>Enterobacterales</i> resistant to carbapenems and cephalosporins observed in isolates from final treated effluent. …”
Get full text

The magnitude and time course of pre-saccadic foveal prediction depend on the conspicuity of the saccade target by Lisa M Kroell, Martin Rolfs

“…Moreover, the time course of foveal enhancement showed an oscillatory pattern that was particularly pronounced at high target opacities. …”
Get full text

Cognitive processing of Chinese verbal irony: the role of reverse adjacency relations in reaction time and accuracy by Mian Huang, Zijian Li, Yu Zheng, Caini Yang

“…Results revealed statistically significant difference across conditions, for experimental ironic sentences (6,012 ms) compared to control (4,901 ms) and baseline sentences (3,987 ms all p &lt; 0.001). Accuracy rates followed a similar pattern, with the experimental condition (64.1%) lower than the control (73.6%) and baseline (82.3%, all p &lt; 0.01). …”
Get full text

Profiles and kinetics of PgRNA and clinical characteristics in pregnant, postpartum, and non-pregnant women with chronic HBV infection by Genju Wang, Yandan Wu, Ziyue Zhang, Qiuchen Wu, Juan Tang, Ying Ji, Yan Wang, Guanlun Zhou, Minmin Yu

“…This study also revealed the patterns of viral activity changes during pregnancy and postpartum, and the first three months postpartum represent a critical period for viral activity changes. …”
Get full text

Nutritional status, dietary inflammatory potential, and risk of osteosarcopenia: the Bushehr Elderly Health (BEH) program by Gita Shafiee, Mehrad Nasiri, Zhaleh Shadman, Mehdi Ebrahimi, Narges Zargar Balajam, Ramin Abdi Dezfouli, Iraj Nabipour, Ramin Heshmat

“…Objective This study sought to explore the relationship between the inflammatory potential of dietary patterns, nutritional intake, and the occurrence of osteosarcopenia in older adults. …”
Get full text

Solar dryers: A review of mechanism, methods and critical analysis of transport models applicable in solar drying of product by Onyinyechi Nnamchi, Cyprian Tom, Godwin Akpan, Murphy Umunna, David Ubong, Mathew Ibeh, Adindu Linus–Chibuezeh, Leonard Akuwueke, Stephen Nnamchi, Augustine Ben, Macmanus Ndukwu

“…Solar drying has been demonstrated to be a sustainable and eco-friendly drying process for drying and preserving agricultural products, offering advantages over traditional methods that include faster drying rates, improved product quality, and reduced energy costs. …”
Get full text

Mutation Profiling of Premalignant Colorectal Neoplasia by Jakub Karczmarski, Krzysztof Goryca, Jacek Pachlewski, Michalina Dabrowska, Kazimiera Pysniak, Agnieszka Paziewska, Maria Kulecka, Malgorzata Lenarcik, Andrzej Mroz, Michal Mikula, Jerzy Ostrowski

“…HGD adenomas had significantly higher mutation rates than LGD adenomas, while LGD-H adenomas exhibited mutation frequencies similar to those of LGD adenomas. …”
Get full text

The Risk of Vestibular Disorders with Semaglutide and Tirzepatide: Findings from a Large Real-World Cohort by Eman A. Toraih, Awwad Alenezy, Mohammad H. Hussein, Shahmeer Hashmat, Saitej Mummadi, Nawaf Farhan Alrawili, Ahmed Abdelmaksoud, Manal S. Fawzy

“…Tirzepatide users demonstrated similar patterns but lower absolute rates (0.10% at 6 months to 0.19% at 3 years vs. controls 0.04% to 0.15%), with hazard ratios from 3.19 (95% CI: 2.11–4.81) to 4.55 (95% CI: 3.43–6.03). …”
Get full text

Assessing Natural Variation as a Baseline for Biodiversity Monitoring: The Case of an East Mediterranean Canyon by Meir Finkel, Ariel Leib Leonid Friedman, Hagar Leschner, Ben Cohen, Hoshen Inbar, Shai Gelbert, Agam Rozen, Eitan Barak, Ido Livne, Ittai Renan, Gilad Ben-Zvi, Orr Comay

“…Despite substantial species turnover rates between periods in all the taxa, almost no change was found regarding the biogeographical origins of plant and beetle species composition. …”
Get full text

Analyzing the Contents of a Large, Public Online Peer Support Forum for Obsessive-Compulsive Disorder: Thematic Analysis by Nora Yanyi Sun, Christopher Pittenger, Terence Ching

“… Abstract BackgroundObsessive-compulsive disorder (OCD) is a debilitating chronic anxiety disorder with low rates of remission. r/OCD is a peer support forum hosted by the Reddit website with over 180,000 users and 100‐200 new posts daily. …”
Get full text

Multimorbidity incidence following hospitalization for SARS-CoV-1 infection or influenza over two decades: a territory-wide retrospective cohort study by Cuiling Wei, Chor Wing Sing, Eric Yuk Fai Wan, Ching Lung Cheung, Ian Chi Kei Wong, Francisco Tsz Tsun Lai

“…Notable differences in the patterns of multimorbidity were identified between the two arms. …”
Get full text

Herbal medicine evaluation for reimbursement-based facial palsy (HERB-FP): a retrospective analysis using Korean health insurance claim data 2020–2024 by Soo-Dam Kim, Man Young Park, Eunbyul Cho, Jiyun Cha, Changsop Yang, Sungha Kim

“…Descriptive and inferential analyses were conducted to examine patient demographics, treatment patterns, symptom progression, and adverse events (AEs). …”
Get full text

Distribution of Pathogenic Bacteria and Drug Resistance in ICU of a Newly Built Hospital by Zeng H, Liu R, Cheng C, Yang N, Luo L, Long S, Zhou R, Yan K, Huang H

“…Drug sensitivity tests indicated a fluctuating resistance rate of Acinetobacter baumannii over the past five years. …”
Get full text

Thymidine kinase 1 expression in ovarian serous adenocarcinoma is superior to Ki-67: A new prognostic biomarker by Jianjun Wang, Qi Liu, Xiaodie Zhou, Yan He, Qing Guo, Qunli Shi, Staffan Eriksson, Ji Zhou, Ellen He, Sven Skog

“…Cancer is a disease with abnormally proliferating cells and therefore proliferation rate is an important index for assessing tumour growth. …”
Get full text

Global burden of liver cancer attributable to drug use: trends from 1990 to 2021 and projections to 2040 by Cong Chen, Ying Zhou, Weiwei Gu, Zhuxin Gu, Pengfei Jia, Luyi Si, Suming Zhao, Hui Zhao

“…Women exhibited higher EAPC values for ASDR (2.36) and DALYs (1.87) compared to men, indicating that the relative rate of increase in the disease burden over time is greater for women. …”
Get full text

Immunohistochemical analysis of IDH1, ATRX, p53, and Ki-67 in glioblastoma and diffuse infiltrative glioma: Therapeutic and prognostic correlation by Hasbay Bermal, Kayaselçuk Fazilet, Süner Halil İbrahim, Tufan Kadir

“…Kaplan-Meier method and Cox proportional regression model (forward model) were used to estimate the mean and median survival times, failure rates, and hazard ratios. Results. In the study, 115 (56.1%) patients were male and 90 (43.9%) were female. …”
Get full text

Definitive urine drug testing in emergency medicine: Recreational and psychiatric drug findings by Thomas G. Rosano, S.M.Touhidul Islam, John M. Rumberger, Robert M. Konetchy, Jr., Michelle Wood, Joseph A. Sorce, Karl A. Robstad, Heather Long

“…Forty percent of patients were also positive for antidepressants and 24% positive for antipsychotics. Significant patterns of co-drug use were found for cocaine, fentanyl, morphine and nicotine. …”
Get full text