Immune-related adverse events of neoadjuvant immunotherapy in patients with perioperative cancer: a machine-learning-driven, decade-long informatics investigation by Yuan Meng, Rong Hu, Song-Bin Guo, Deng-Yao Liu, Zhen-Zhong Zhou, Hai-Long Li, Wei-Juan Huang, Xiao-Peng Tian

“…During the past decade, the amount of research in the field of NAI safety has displayed a positive trend (annual growth rate: 30.2%), and it has achieved good global collaboration (international coauthorship: 17.43%). …”
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Lipidomic analyses reveal the dysregulation of oxidized fatty acids (OxFAs) and acyl-carnitines (CARs) in major depressive disorder: a case-control study by Lei He, Na Duan, Chong Wang, Ru Shan, Jing Li, Lin Wang, Qiuli Liu, Junwei Tao, Li Liu, Xiaoliang Ma, Bing Cao

“…Results Based on the filtering criteria of false discovery rate (FDR) -adjusted P < 0.05, variable importance in projection (VIP) > 1.5, and fold change (FC) > 2.0 or < 0.5, a total of 40 lipids were identified as significantly different. …”
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Path to Heritagization in Landscape Architecture: A Review of the Regeneration Design of Beijing Changchunyuan Park by Yufan ZHU

“…This place is a gathering of temples and guild halls and a primary access route to Xuanwu Gate which is the southern gateway to the imperial city. …”
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Identification of DNA Methylation Differences in Pituitary Tissues of Sichuan White Geese Using Whole-Genome Bisulfite Sequencing (WGBS) by Lin Ma, Xianzhi Zhao, Guoda A, Tongtong Song, Meng Wu, Zhihao Yan, Min Xiao, Wenbo Jiang, Yixiao Gao, Haiwei Wang, Zhuping Chen, Keshan Zhang, Jiajia Xue, Yi Luo, Chao Wang, Youhui Xie, Ying Chen, Guangliang Gao, Qigui Wang

“…We achieved high-quality sequencing data (mean 19.09 Gb raw reads, 15.49 Gb clean reads, 79.1% unique mapping rate) with a bisulfite conversion efficiency of 99.88%. …”
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Effects of different exercise modalities on blood pressure and endothelial function in prehypertension individuals: a systematic review and network meta-analysis by Yingtian Yang, Qianyu Lv, Xinzheng Hou, Yanfei Lv, Xirui Zhang, Qian Wu, Xuejiao Ye, Chenyan Yang, Mingyu Huang, Shihan Wang

“…The surface underneath the cumulative ranking curve data was utilized to rate interventions. Confidence was evaluated using the CINeMA framework.ResultsA total of 18 articles with 2,592 individuals were included in the NMA. …”
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Cross sectional associations of physical activity and sleep with mental health among Chinese university students by Bo Li, Shan-shan Han, Yu-peng Ye, Ya-xing Li, Shu-qiao Meng, Shuo Feng, Han Li, Zhong-lei Cui, Yang-Sheng Zhang, Yao Zhang, Qing Zhang, Guang-xu Wang, Hu Lou, Weidong Zhu, Yang Liu

“…The participants’ PA behaviors, sleep patterns, depressive symptoms (use the CES-D), anxiety symptoms (use the GAD-7), smoking and drinking behaviors, and demographic information were assessed through an online questionnaire using Questionnaire Star software. …”
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Multi-view fusion of diffusion MRI microstructural models: a preterm birth study by Rosella Trò, Monica Roascio, Domenico Tortora, Mariasavina Severino, Andrea Rossi, Andrea Rossi, Eleftherios Garyfallidis, Gabriele Arnulfo, Gabriele Arnulfo, Marco Massimo Fato, Shreyas Fadnavis

“…Furthermore, we investigated discriminative patterns of preterm birth using multiple analysis methods, drawn from two only seemingly divergent modeling goals, namely inference and prediction. …”
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Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis by Takuya Murao, Gaifeng Ma, Atsushi Murao, Alok Jha, Jingsong Li, Yongchan Lee, Mian Zhou, Ping Wang, Ping Wang, Monowar Aziz, Monowar Aziz

“…Endogenous molecules released from stressed or damaged cells, known as damage-associated molecular patterns (DAMPs), exacerbate inflammation, organ injury, and mortality in sepsis. …”
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Climate change-induced shifts in landslide susceptibility in São Sebastião (southeastern Brazil) by Enner Alcântara, Cheila Flávia Baião, Yasmim Carvalho Guimarães, José Antonio Marengo, José Roberto Mantovani

“…Frequency Ratio (FR) analysis revealed varying levels of landslide susceptibility across scenarios, with RCP2.6 showing lower probabilities for moderate landslides (FR: 0.007946) compared to higher ratings for RCP4.5, RCP6.0, and RCP8.5 (FR: 1.663156 for high landslides). …”
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Protocol for Rhapsody: a longitudinal observational study examining the feasibility of speech phenotyping for remote assessment of neurodegenerative and psychiatric disorders by Allan H Young, Rebecca Strawbridge, Ammar Al-Chalabi, Dag Aarsland, Aleksandra Podlewska, Ray Chaudhuri, Elliot Hampsey, Marton Meszaros, Caroline Skirrow, Rosie H Taylor, Lazarus Chok, Jack Weston, Emil Fristed, Olabisi Awogbemila

“…Additionally, the study evaluates if acoustic and linguistic patterns can predict diagnostic group, as measured by the sensitivity, specificity, Cohen’s kappa and area under the receiver operating characteristic curve of the binary classifiers distinguishing each diagnostic group from each other. …”
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Prospective Study of the Association Between Frailty and Health Care Utilization in Patients With Advanced CKD by Alice L. Kennard, Alice M. Richardson, Suzanne Rainsford, Kelly L. Hamilton, Nicholas J. Glasgow, Kate L. Pumpa, Angela M. Douglas, Girish S. Talaulikar

“…Negative binomial regression was used to model health care utilization patterns. Frailty progression over study follow-up was described using Cox proportional hazards modelling. …”
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Watching live performances enhances subjective and physiological emotional responses compared to viewing the same performance on screen by Damien Gabriel, Julie Devos, Sandrine Chapuis, Alexandre Comte, Pierre-Edouard Billot

“…Heart rate increased with musical intensity in both conditions, while EEG data showed reduced arousal levels during the live performance, possibly reflecting deeper cognitive absorption. …”
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Cutibacterium acnes lysate improves cellular response against Candida albicans, Escherichia coli and Gardnerella vaginalis in an in vitro model of vaginal infection by Francesco Ricchi, Samyr Kenno, Natalia Pedretti, Giulia Brenna, Francesco De Seta, Francesco De Seta, Andrea Ardizzoni, Eva Pericolini

“…This event triggers the onset of gynecological infectious diseases, normally treated with antimicrobial drugs, considered to date as the gold standard; yet the increasing rate of drug resistance requires novel approaches and alternative therapeutic strategies. …”
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Accurate V2X traffic prediction with deep learning architectures by Ali R. Abdellah, Ahmed Abdelmoaty, Abdelhamied A. Ateya, Abdelhamied A. Ateya, Ahmed A. Abd El-Latif, Ahmed A. Abd El-Latif, Ammar Muthanna, Ammar Muthanna, Andrey Koucheryavy

“…We employ Bidirectional Long Short-Term Memory (BiLSTM) networks and compare their performance against other prominent DL architectures, including unidirectional LSTM and Gated Recurrent Unit (GRU). Our findings demonstrate that the BiLSTM model exhibits superior accuracy in predicting traffic patterns. …”
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SOH Estimation Method for Lithium-Ion Batteries Using Partial Discharge Curves Based on CGKAN by Shengfeng He, Wenhu Qin, Zhonghua Yun, Chao Wu, Chongbin Sun

“…Next, a SOH estimation framework based on the CGKAN model is developed, where 1-Dimensional-Convolutional Neural Networks (1D-CNN) are used to extract deep features from the original data, Bidirectional Gated Recurrent Unit (BiGRU) captures the bidirectional dependencies of the time series, and Kolmogorov–Arnold Networks (KAN) enhances the modeling of complex nonlinear features through its nonlinear mapping capabilities, thereby improving the accuracy of SOH estimation. …”
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Modeling heterogeneity in cognitive trajectories in the Framingham Heart Study by Yuan Fang, Jiachen Chen, Jesse Mez, Jesse Mez, Jesse Mez, Claudia L. Satizabal, Claudia L. Satizabal, Claudia L. Satizabal, Michael L. Alosco, Michael L. Alosco, Michael L. Alosco, Wei Qiao Qiu, Wei Qiao Qiu, Wei Qiao Qiu, Margaret F. Doyle, Joanne M. Murabito, Joanne M. Murabito, Joanne M. Murabito, Kathryn L. Lunetta

“…IntroductionThe prevalence of cognitive impairment in the population is growing; however, there is substantial heterogeneity in the rate of decline across different cognitive domains. …”
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Analysis of Consistency Between Forensic Psychiatric Evaluation Diagnosis and Previous Clinical Psychiatric Diagnosis: A Retrospective Study by Li M, Cao Y, Wang X, Li L, Wu C, Yi X, Wang K, Zheng H, Liu Y, Xiong Z, Gong J, Ji Q

“…Diagnostic agreement was evaluated using the kappa coefficient.Results: (1) Among 78 cases, 43 had a history of mental illness, with a prevalence rate of 55.13%; (2) The evaluation diagnosis was consistent with the previous diagnosis in 12 cases (27.91%) and inconsistent in 31 cases (72.09%), with Kappa=0.243 (P< 0.05), indicating poor consistency; (3) Schizophrenia (21 cases, 48.84%) and mood disorders (14 cases, 32.56%) were the most common in previous diagnoses; (4) Evaluation diagnoses were mainly no mental illness (38 cases, 48.72%) and physiological passion (8 cases, 10.26%).Conclusion: In criminal cases where the forensic evaluation diagnosis is no mental illness, the consistency between the evaluation diagnosis and the previous diagnosis is low, which is closely related to the differences in thinking patterns and assessment focus between forensic evaluation and clinical diagnosis. …”
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Eco-friendly silver nanoparticles from garlic: a novel therapeutic approach for treating Escherichia fergusonii wound infections by Sozan M. Abdelkhalig, Arwa Gamal Ali, Mohamed Farouk Ghaly, Nada K. Alharbi, Maha Alharbi, Mahmoud M. Bendary, Amira I. Abousaty

“…ResultsGenetic sequencing of 16S rRNA gene, aligned with phenotypic identification methods, confirmed that Escherichia fergusonii (E. fergusonii) as a significant atypical pathogen responsible for complicated wound infections, with a prevalence rate of 24% (12 out of 50 cases). Antimicrobial susceptibility testing revealed that all identified E. fergusonii strains exhibited MDR patterns. …”
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An explainable AI framework for spatiotemporal risk factor analysis in public health: a case study of cardiovascular mortality in South Korea by Eunjin Kang, Dongjin Cho, Siwoo Lee, Jungho Im, Dongwook Lee, Cheolhee Yoo

“…In two complementary schemes, the most explainable factor to districts with high CVD-ASMR was low education level related to sociodemographic vulnerability, whereas the most explainable factors to high temporal CVD-ASMR patterns were low greenness and high air pollution levels. …”
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Stomata as the Main Pathway for the Penetration of Atmospheric Particulate Matter Pb into Wheat Leaves by Ke Zhang, Yujing Liang, Chuang Ma, Haopeng Guo, Fuyong Liu, Aihua Gao, Nan Liu, Hongzhong Zhang

“…In this study, spraying Pb(NO₃)₂ (Treatment T1) and spraying PbS (Treatment T2) were used as soluble and insoluble Pb, respectively, to evaluate the primary pathways of APM-Pb absorption by wheat leaves, as well as the translocation and accumulation patterns of Pb within the wheat plant. The results showed that both soluble and insoluble Pb can be absorbed by wheat leaves. …”
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