Scalable Clustering of Complex ECG Health Data: Big Data Clustering Analysis with UMAP and HDBSCAN by Vladislav Kaverinskiy, Illya Chaikovsky, Anton Mnevets, Tatiana Ryzhenko, Mykhailo Bocharov, Kyrylo Malakhov

“…The focus is on identifying patterns that correlate with cardiac health risks, potentially aiding in early detection and personalized care. …”
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Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma by Liuyan Chen, Lvying Wu, Minying Tang, Yuanhang Cheng, Kuanyin Wang, Jianan Zhang, Wenyi Deng, Lingfeng Zhu, Jin Chen

“…We analysed its expression patterns, prognostic and diagnostic value, and potential mechanisms. …”
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Front‐line treatment efficacy and clinical outcomes of elderly patients with multiple myeloma in a real‐world setting: A multicenter retrospective study in China by Li Bao, Ai‐Jun Liu, Bin Chu, Qian Wang, Yu‐Jun Dong, Min‐Qiu Lu, Lei Shi, Shan Gao, Yu‐Tong Wang, Li‐Fang Wang, Wen‐Ming Chen, Jun‐Ling Zhuang

“…Methods We retrospectively analyzed the treatment patterns and outcomes of 328 Chinese patients (≥65 years) with MM in a real‐world setting. …”
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Evaluation of lung cancer early detection offered by the German Social Accident Insurance for formerly asbestos-exposed employees using low-dose computed tomography – setting and s... by Felix Greiner, Jan Heidrich, Helena Keller, Dirk Taeger, Thorsten Wiethege, Volker Harth

“…Primary endpoints are participation patterns, the rate of findings requiring further diagnostic investigation, the detection of lung cancer including tumour stage and characteristics, and the notification and recognition of asbestos-related occupational diseases. …”
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Clinical management and analysis of immune-related adverse events in neoadjuvant immunotherapy for locally advanced rectal cancer by AN Yang, WANG Chentong, QIU Xiaoyuan, ZHOU Jiaolin, LIN Guole

“…Descriptive statistics were used to summarize irAEs patterns and management approaches. Results: A total of 41 irAE episodes occurred among the 30 patients. …”
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Global, regional, and national burden of male breast cancer and predictions in the next 30 years: a systematic analysis of the global burden of disease study 2021 by YaRong Wang, Liang Wang, Bei Yu, Shuang Wen, Xiaoxi Mou, Lin Yang

“…Given these trends, male breast cancer remains a significant global health concern, and emerging disease patterns must inform new control policies.…”
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Air leakage characteristics and comprehensive prevention of goaf side retained roadway of fully mechanized mining faces in Qincheng coal mine by Xin Luo, Liang Chen, Bing Wu, Mengchen Sun, Tao Yang, Hongyang Yu

“…Abstract Mastering the deformation and air leakage patterns of gob-side retained roadway in fully mechanized mining faces, as well as the distribution characteristics of the gas flow field, is of great significance for the comprehensive prevention and control of gas in the goaf. …”
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Sleep Restriction and Weekend Sleep Compensation Relate to Eating Behavior in School-Aged Children by Chamorro R, Garrido-González M, Gutierrez M, Santos JL, Weisstaub G

“…Actigraphic recordings measured sleep patterns for 4 consecutive days, including a weekend day. …”
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The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis by Yan Zhang, Yan Zhang, Xueju Wang, Xuefeng Wang, Gengdi Huang

“…Group ICA was used to identify ROIs and assessed inter-group differences in neural activity using false discovery rate (FDR) correction.ResultsCompared to the HC, increased activity was observed in the right frontal operculum cortex, right insular cortex, right inferior frontal gyrus (pars opercularis), and right frontal pole in TN patients. …”
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At-Home Stroke Neurorehabilitation: Early Findings with the NeuroExo BCI System by Juan José González-España, Lianne Sánchez-Rodríguez, Maxine Annel Pacheco-Ramírez, Jeff Feng, Kathryn Nedley, Shuo-Hsiu Chang, Gerard E. Francisco, Jose L. Contreras-Vidal

“…Furthermore, linear mixed-effects statistical models showed a significant reduction in trial duration (<i>p</i>-value < 0.02) and concomitant changes in brain patterns (<i>p</i>-value < 0.02). Conclusions: the analysis of these findings suggests that a low-cost, safe, simple-to-use BMI system for at-home stroke rehabilitation is feasible.…”
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Clinico-epidemiological and immunological characteristics of rickettsioses in a Sri Lankan patient cohort 2018–2023 by Nayana Gunathilaka, Nilmini Chandrasena, Hemantha Sudusinghe, Vidusha Nethsara Mudalpath, Deshaka Jayakody, Ranjan Premaratna

“…Understanding epidemiological patterns and clinical manifestations is crucial for developing effective surveillance and prevention strategies. …”
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Association between D-dimer and in-hospital mortality risk in Acute Kidney Injury based on latent class dynamic trajectory by Lixiang Rao, Jiazheng Sun, Xingyang Zhao, Shuwang Ge, Ningxu Li

“…Kaplan-Meier survival curves indicated a reduced in-hospital survival rate in the high-peak decline group (p &lt; 0.05). …”
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Bacterial isolates and antibiotic resistance in critically ill sepsis patients at a tertiary hospital in Ethiopia by Girum Tesfaye Kiya, Zeleke Mekonnen, Elsah Tegene Asefa, Esayas Kebede Gudina, Hanan Ahmed, Getenet Beyene, Mekidim Mekonnen, Gemeda Abebe

“…Current understanding of bacterial profiles, antibiotic resistance patterns, and the magnitude of Extended-Spectrum Beta-Lactamase (ESBL) and Carbapenemase (CP) producing isolates in critically ill patients is vital for implementing strong management approaches tailored to combat antibiotic resistance and improve patient outcomes. …”
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Understanding the triacylglycerol-based carbon anabolic differentiation in Cyperus esculentus and Cyperus rotundus developing tubers via transcriptomic and metabolomic approaches by Honglin Zhang, Zhitao Zhu, Yining Di, Jixun Luo, Xianyue Su, Yong Shen, Qing Liu, Tao Liu, Xiaoyu Xu

“…Our findings indicate distinct expression patterns of key regulatory genes involved in TAG biosynthesis and lipid droplet formation, including transcriptional factors and structural genes such as ABI3 transcriptional factor, rate-limiting enzymes GPAT3/6/9 and DGAT2/3, and oleosin and caleosin homologs. …”
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Identification of Specific Abnormal Brain Functional Activity and Connectivity in Cancer Pain Patients: A Preliminary Resting-State fMRI Study by Hua Y, Geng Y, Liu S, Xia S, Liu Y, Cheng S, Chen C, Pang C, Zhao Z, Peng B, Dai Y, Ji J, Wu D

“…Statistical results indicated that there was no significant correlation between pain scores (Numeric Rating Scale, NRS) and neuroimaging metrics. According to the machine learning classification, the FC features of the right precentral gyrus achieved higher diagnostic efficacy (AUC = 0.804) compared to ALFF and ReHo in distinguishing between CP patients and HCs.Conclusion: Brain activity and FC in CP patients show abnormalities in regions such as the inferior temporal gyrus, middle temporal gyrus, prefrontal cortex, parietal lobe, and cerebellum. …”
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Analysis of ALPS‐Index: Difference in Type 2 Diabetes Mellitus With or Without Mild Cognitive Impairment and Its Relationship With Hippocampal Microstructure by Ziyu Diao, Xuan Huang, Die Shen, Kun Wang, Jiahe Wang, Kui Zhao, Chen Zhao, Zidong Cao, Xin Tan, Shijun Qiu

“…ABSTRACT Introduction Type 2 diabetes mellitus (T2DM) with cognitive impairment has a high incidence rate globally, and there is a need to investigate the relationship among the glymphatic system, hippocampus microstructure, and cognition in T2DM. …”
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Meteorological determinants of hepatitis E dynamics in Jiangsu Province, China: a pre-COVID-19 era study focusing on multi-route transmission (2005–2018) by Peihua Li, Jia Rui, Kangguo Li, Deng Bin, Hongjie Wei, Xi Tan, Tianmu Chen

“…The MHMRTDM quantified transmission rate coefficients (β, βw and βp′). GAMs linked the transmission coefficients and incidence to meteorological factors, validated using 2017–2018 data.ResultsThe optimal GAM integrated with the MHMRTDM was established (lowest GCV = 1.705 × 10−21, R2 = 0.980, lowest RMSE = 3.682 × 10−11, lowest MAE = 2.987 × 10−11). …”
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The relationship between social isolation and cognitive function in older patients with chronic obstructive pulmonary disease: a latent profile analysis by Minghua Han, Hongxia Wu, Huize Xu, Jian Zhao, Zhongwen Chang, Qian Zhao

“…The general information questionnaire, Social Network Scale Brief, Hamilton Depression Scale, Social Support Rating Scale, and Montreal Cognitive Assessment Scale were employed. …”
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Components of clean delivery kits and newborn mortality in the Zambia Chlorhexidine Application Trial (ZamCAT): An observational study. by Jason H Park, Davidson H Hamer, Reuben Mbewe, Nancy A Scott, Julie M Herlihy, Kojo Yeboah-Antwi, Katherine E A Semrau

“…In examining perinatal mortality (stillbirth plus neonatal death in the first 7 days of life), similar patterns were observed. There was no significant reduction in risk of late newborn mortality (7-28 days) with CDK use. …”
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Removing Excess Iron from Sewage and Natural Waters: Selecting Optimal Sorbent by Ludmila A. Ivanova, Irina V. Timoshchuk, Alena K. Gorelkina, Ekaterina S. Mikhaylova, Nadezhda S. Golubeva, Evgeny N. Neverov, Tamara A. Utrobina

“…The research objective was to select the most efficient sorption material to eliminate water from iron, as well as to establish the adsorption patterns for different sorbents, thus creating sustainable and effective purification. …”
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