Calcium and Potassium Channels in Experimental Subarachnoid Hemorrhage and Transient Global Ischemia by Marcel A. Kamp, Maxine Dibué, Toni Schneider, Hans-Jakob Steiger, Daniel Hänggi

“…Initial hypoperfusion after exposure of cerebral vessels to oxyhemoglobin correlates with a suppression of voltage-gated potassium channel activity, whereas delayed cerebral vasospasm involves changes in other potassium channel and voltage-gated calcium channels expression and function. …”
Get full text

Unveiling the Complexities of Medications, Substance Abuse, and Plants for Recreational and Narcotic Purposes: An In-Depth Analysis by Iasmina-Alexandra Predescu, Alex-Robert Jîjie, Dalia Pătraşcu, Aida-Luisa-Vanessa Pasc, Elisaveta-Ligia Piroş, Cristina Trandafirescu, Cristian Oancea, Cristina Adriana Dehelean, Elena-Alina Moacă

“…This review highlights the complexities surrounding the consumption of chemical substances in excess or for non-medical purposes, obtained through legal prescriptions, over-the-counter purchases, or illicit means, with an emphasis on the predictive role of stressors and individual-level variables in the development of substance use disorders, as well as the influence of the regulatory environment on patterns of consumption. Additionally, the alarming escalation in the mortality rate associated with illicit drug and opioid overdoses is also underscored. …”
Get full text

An interactive course program on nutrition for medical students: interdisciplinary development and mixed-methods evaluation by Gonza B. Ngoumou, Daniela A. Koppold, Laetitia Wenzel, Anne Schirmaier, Carolin Breinlinger, Lisa M. Pörtner, Stefan Jordan, Julia K. Schiele, Etienne Hanslian, Annika Koppold, Beate Stock-Schröer, Dimitra M. Varvarezou, Michael Jeitler, Miriam Ortiz, Andreas Michalsen, Wiebke Stritter, Georg Seifert, Christian S. Kessler

“…Abstract Nutrition plays a crucial role in human and planetary health, as prevailing nutritional patterns significantly contribute to the global non-communicable disease pandemic. …”
Get full text

Circulating respiratory viruses including SARS-CoV-2 during 2021–2022 season in Tunisia: Epidemiological and dynamic changes by Awatef Taktak, Saba Gargouri, Amel Chtourou, Fahmi Smaoui, Rim Karray, Noureddine Rekik, Lamia Feki-Berrajah, Héla Karray-Hakim

“…Background: Changing patterns in community respiratory virus activity were reported in different geographical locations during the COVID-19 pandemic. …”
Get full text

Functional Ultrasound Imaging of Cocaine Induced Brain-Wide Neurovascular Response by Shaoyuan Yan, Nan Huang, Yusheng Tong, Yousheng Shu, Qiumin Le, Dean Ta, Kailiang Xu

“…In the cortex, the observed CBV changes responded more rapidly to cocaine than local field potential (LFP) activities, indicating that prior to acting on the central nervous system, cocaine may first affect the peripheral nervous system, accelerating heart rate and increasing cardiac output. Both hemodynamic and neural responses showed opposing patterns between cortical and VTA brain regions. …”
Get full text

Wetland key habitat functional areas in China informed by flagship waterbirds: Past changes, present status and future trend with modeling scenarios by Hengxing Xiang, Dehua Mao, Ming Wang, Yeqiao Wang, Chi-Yeung Choi, Wenjuan Wang, Haitao Wu, Kaidong Feng, Zongming Wang

“…This study identifies the past changes, present status, and future patterns of wetland KHFAs in China by using the Zonation model with comprehensive data inputs, including wetland distribution, key bird distribution areas (such as Ramsar sites and Important Bird Areas), and flagship waterbird species. …”
Get full text

A new ICT system coupling electromyography and coma recovery scale-revised to support the diagnostic process in disorders of consciousness by Francesca Giulia Magnani, Simone Toffoli, Martina Cacciatore, Camilla Ippoliti, Filippo Barbadoro, Milad Malavolti, Francesca Lunardini, Jorge Navarro, Guya Devalle, Maurizio Lanfranchi, Valeria Pingue, Sara Marelli, Luigi Ferini Strambi, Matilde Leonardi, Davide Sebastiano Rossi, Davide Sattin, Simona Ferrante

“…However, the misdiagnosis rate is around 40%. For this reason, recent guidelines suggested enhancing the assessment with neurophysiological measures: among these, surface electromyography (sEMG) represents a convenient bedside solution. …”
Get full text

Acute alcohol intoxication among adolescents in Italy, the Netherlands and Belgium: a cross-national hospital chart comparison study by Stijn Verhulst, Nico van der Lely, Andrea Orsi, Giancarlo Icardi, Guido Van Hal, Hanna van Roozendaal, Louise Pigeaud, Allegra Ferrari, Loes de Veld, Inge Glazemakers, Jozef De Dooy

“…Comprehensive data on adolescent drinking patterns is crucial for developing effective prevention strategies. …”
Get full text

Urban Expansion and Land Use Transformations in Midnapore City (2003–2024): Implications for Sustainable Development by Rakesh Ranjan Thakur, Debabrata Nandi, Anoop Kumar Shukla, Subhasmita Das, Sasmita Chand, Pankaj Singha, Roshan Beuria, Chetan Sharma

“…Amidst global shifts in land use patterns due to urbanization, this study focuses on the rapid land use and land cover (LULC) changes in Midnapore City during the periods 2003–2014 and 2014–2024. …”
Get full text

Evaluation of the Effects of Anesthetics and Surgery on Sleep Quality in Patients Undergoing Posterior Spinal Instrumentation Surgery: A Prospective Randomised Clinical Trial by Selcan Akesen, Gökay Eken, Yücel Bilgin, Saltuk Buğra Güler, Elifgül Ulutaş

“…Introduction: The aim of the study is to evaluate the impact of the anesthesia methods and surgical procedure on the sleep patterns and sleep quality of patients undergoing posterior spinal instrumentation, using the Pittsburgh Insomnia Rating Scale-20 (PIRS-20). …”
Get full text

Aligning the principles and practice of research integrity and research fairness in global health: a mixed-methods study by Sandra Alba, Rutuja Patil, Martijn Wienia, Masja Straetemans, Francis Kombe, Gowri Gopalakrishna, Harry Coleman, Nima Yaghmaei, Joseph Bukulu Sempa, Jake D Mathewson, Hannah Kabelka, Preeti Sohoni

“…The dual objectives were to quantify the frequency of practices related to research integrity and fairness and explore the determinants influencing these practices in global health.Results Out of 145 participants in the quantitative survey (8.4% response rate), findings indicate that global health researchers generally adhere to principles of research integrity and fairness, with variations in reported behaviours. …”
Get full text

Uncovering genetic contributors to developmental delay and intellectual disability: a focus on CNVs in pediatric patients by Yilun Tao, Yilun Tao, Hongzhi Guo, Dong Han, Miao Yang, Ting Lun, Lihong Wang, Wenxia Song, Haiwei Wang, Xiaoze Li

“…CNV pathogenicity was assessed using established databases and ACMG guidelines, with inheritance patterns determined where possible.ResultsAcross the 99 patients, 43 CNVs were identified in 40 individuals, with 32 classified as clinically significant, resulting in a diagnostic rate of 30.3%. …”
Get full text

Temperature drives the variations in cropland exposure to compound drought and heatwave events under future climate in Northeast China by Chuanwei Zhang, Jiangbo Gao, Lulu Liu, Yanjun Shen, Shaohong Wu

“…Notably, adherence to the SSP126 pathway can reduce both the increase rate of CDHW magnitude and cropland exposure compared to other SSPs. …”
Get full text

Defining the sensitivity of cosmic ray muons to groundwater storage changes by Tramontini, Matías, Rosas-Carbajal, Marina, Zyserman, Fabio Iván,  Longuevergne, Laurent, Nussbaum, Christophe, Marteau, Jacques

“…Comparisons with river stream flow, and volumetric soil water content data, show similar variation patterns to the groundwater estimates from our muon measurements. …”
Get full text

Organ-specific safety profile of bioinspired short antimicrobial peptides in zebrafish embryos by Sahar Isa Da’as, Sahar Isa Da’as, Hajira Afreen, Aseela Fathima, Ahmad M. Hani, Nura A. Mohamed, Md Mizanur Rahman, Patrick G. Burgon, Sergio Crovella, Haissam Abou-Saleh

“…Peptide E exhibited developmental toxicity at concentrations above 100 μg/mL, along with cardiotoxic effects such as reduced heart rate, variable locomotion patterns, and clear hepatotoxic responses.ConclusionThis study highlights distinct organ-specific toxicity profiles for Peptides C and E and underscores the importance of careful preclinical evaluation of BSAMPs. …”
Get full text

CFD, energy, and exergy analysis and sustainability indicators of tilapia fish strips drying using an evacuated tubes indirect solar dryer by Amena Ali Alsakran, Omar Shahat Younis, András Székács, Omar Saeed, Mohamed Hamdy Eid, Ali Majrashi, Atef Fathy Ahmed, Aml Abubakr Tantawy, Abdallah Elshawadfy Elwakeel

“…The optimal air flow rate of 0.03 m3/s provided a uniform drying temperature of 74.82 °C, at solar noon. …”
Get full text

Landscape analysis of m6A modification regulators reveals LRPPRC as a key modulator in tubule cells for DKD: a multi-omics study by Li Jiang, Hongda Yu, Jie Jian, Xulin Sai, Yudian Wang, Yufei Zhang, Xiai Wu

“…In clinical patients, the expression levels of LRPPRC mRNA in DKD showed the tendency to be downregulated and exhibited the potential correlations with Glomerular Filtration Rate (GFR) and proteinuria according to the Nephroseq database. …”
Get full text

AI-DBS study: protocol for a longitudinal prospective observational cohort study of patients with Parkinson’s disease for the development of neuronal fingerprints using artificial... by Martijn Beudel, Rick Schuurman, Rob M A de Bie, Deborah Hubers, Mariëlle J Stam, Martijn G J de Neeling, Bart J Keulen, Arthur W G Buijink, Bernadette C M van Wijk

“…The objective of the AI-DBS study is to identify patient-specific patterns of neuronal activity that are associated with the severity of motor symptoms of PD. …”
Get full text

Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial by Xue Gao, Lu Liu, Mei-Rong Pan, Hai-Mei Li, Yu-Feng Wang, Xue-Ying Liu, Zhong-Fang Fu, Qiujin Qian

“…Introduction Emotional disorders are highly prevalent among adolescents, with a high rate of comorbidity. Convenient and effective treatment options are needed to reduce costs and improve effectiveness. …”
Get full text

Ecological drivers of nesting behavior in a subtropical city: An observational study on spotted doves by Yao Sheng, Mengjie Lu, Junpeng Bai, Xiaobin Xie, Long Ma, Wanyou Li, Zhen Zhang, Fang Ming, Xueli Zhang, Ziwei Zhang, Zhifeng Xu, Yuqing Han, Bicai Guan, Luzhang Ruan

“…The results revealed that the nest reuse rate was 38.08% (n = 115). Nests closer to trunk, with lower nest position and higher large‐scale urbanization score tended to have higher reuse rate. …”
Get full text