EQ-5D utility, response and drug survival in rheumatoid arthritis patients on biologic monotherapy: A prospective observational study of patients registered in the south Swedish SS... by Tanja Schjødt Jørgensen, Carl Turesson, Meliha Kapetanovic, Martin Englund, Aleksandra Turkiewicz, Robin Christensen, Henning Bliddal, Pierre Geborek, Lars Erik Kristensen

“…Overall, DAS28 defined remission and low disease activity were achieved in 20% and 43% of patients, respectively. Drug survival rates were statistically significantly different between bDMARDs (p = 0.01), with the highest rates observed for rituximab, followed by etanercept. …”
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Integrating AI-generated content tools in higher education: a comparative analysis of interdisciplinary learning outcomes by Zhang Yan, Tang Qianjun

“…Findings revealed a 37% increase in interdisciplinary project outcomes (measured by collaborative problem-solving scores, cross-domain knowledge integration ratings, and peer evaluation metrics) when AIGC tools were strategically implemented, with significant variations in effectiveness based on implementation approach. …”
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Barriers and facilitators to implementing a task-sharing mental health intervention for Sickle Cell Disease populations in low- and middle-income countries: a qualitative analysis... by John Patena, Leah Elster, Tania Hameed, Sumedha Kulkarni, Alden Yuanhong Lai, Annika C. Sweetland, Joyce Gyamfi, Temitope Ojo, Angela Odoms-Young, Charmaine Royal, Emmanuel Peprah

“…BackgroundPeople living with Sickle Cell Disease (SCD) experience higher rates of common mental disorders (CMD). There is an alarming treatment gap in the provision of adequate mental health services for CMDs in low- and middle-income countries (LMIC). …”
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Triatoma dimidiata, domestic animals and acute Chagas disease: a 10-year follow-up after an eco-bio-social intervention by Jose G. Juarez, Andrea M. Moller-Vasquez, María Granados-Presa, Pamela Pennington, Norma Padilla, Sujata Balasubramanian, Lisa D. Auckland, Elsa Berganza, Estuardo Alvarado Liberato, Henry Esquivel, Ranferi Trampe, Louisa A. Messenger, Celia Cordón-Rosales, Gabriel L. Hamer, Sarah A. Hamer

“…Results Persistent household infestation by T. dimidiata was observed across all four communities, with infestation rates ranging from 17% to 38% and colonization levels ranging from 9% to 29%. …”
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Mapping Antimicrobial Resistance in <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> from Complicated Urinary Tract Infections in Oman: Phenotypic and Genotypic Insights by Nawal AL Shizawi, Zaaima AL Jabri, Fatima Khan, Hiba Sami, Turkiya AL Siyabi, Zakariya AL Muharrmi, Srinivasa Rao Sirasanagandla, Meher Rizvi

“…In comparison, susceptibility rates of <i>K. pneumoniae</i> were far lower: nitrofurantoin (38%), fosfomycin (89%), aminoglycosides (82%), piperacillin-tazobactam (72%), and carbapenems (83%). …”
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Spatio-Temporal Characteristics and Driving Forces of Landscape Ecological Risks in Highly Urbanized Areas: A Case Study of Suzhou City by Lingyue LU, Dawei SHAO, Dianming WU

“…However, relatively little attention has been given to urbanized areas characterized by high rates of population growth and land development. …”
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A longitudinal qualitative study of clinical nurses caring for hospitalized adults during the first fifteen months of COVID-19: lessons in professional survival and leadership by Elizabeth M. Norman, Mildred Ortu Kowalski, Roxanne Sabatini, Carol S. Jones, Wendy Silverstein

“…At the time of this April surge, nurses were exposed to a virus with no standard treatments and high mortality rates. Using a longitudinal qualitative design, the team hoped to answer questions about what compelled these nurses to continue to come to work? …”
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Electrical Capacitance Probe Characterization in Vertical Annular Two-Phase Flow by Grazia Monni, Mario De Salve, Bruno Panella, Carlo Randaccio

“…The ECP is used to investigate a vertical air/water flow, characterized by void fraction higher than 95%, with mass flow rates ranging from 0.094 to 0.15 kg/s for air and from 0.002 to 0.021 kg/s for water, corresponding to an annular flow pattern. …”
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Clinical and epidemiological characteristics of registered childhood tuberculosis cases in the North-Western Region of Russia when introducing a tuberculosis diagnosis complex usin... by I. F. Dovgalyuk, N. V. Korneva, A. A. Starshinova, Yu. E. Ovchinnikova, S. M. Ananyev

“…The findings were compared with registered morbidity rates and changes in the set of performed examinations [introduction of diaskintest (DST) and computed tomography (CT)] in 5 areas of the North-Western Region of the Russian Federation. …”
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Construction and Validation of an Oxidative Phosphorylation Signature in High-Grade Glioma and Potential Inhibitors Screening by Hanwen Lu, Wenpeng Zhao, Bingchang Zhang, Yuanyuan Xie, Jiawei He, Huiying Yang, Zhanxiang Wang

“…Glioma is a devastating type of brain tumor with high morbidity and mortality rates. Despite current treatment options, the prognosis for glioma patients remains poor. …”
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Effective temperature in approximate quantum many-body states by Yu-Qin Chen, Shi-Xin Zhang

“…Our findings reveal a consistent exponential pattern in the energy eigenbasis decomposition contributions of approximate states across different ansatzes, optimization objectives, and quantum systems, characterized by remarkably small decay rates, i.e., high effective temperatures. …”
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Monetary Policy and Financial (In)Stability by Adam Koronowski

“…It is not surprising that it consists of cutting interest rates and bail-out of insolvent, systemically important financial institutions. …”
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Design of a High-Gain, Slotted Ultra-Wideband Antenna with T-shaped slots for Millimeter-Wave Applications by hassan falih

“…Millimeter wave (mmWave) is a crucial frequency range for fifth-generation (5G) mobile communication, characterized by wide bandwidth and higher data rates. Antenna components will be small, wideband, and high-gain for use in 5G systems. …”
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Dorsal epidural disc migration—MRI characteristics and surgical microdiscectomy treatment: Case report and review of the literature by Antonios Michailidis, MD, Ioannis Tsifountoudis, MD, PhD, Dimitrios Kitridis, MD, FEBOT, MSc, PhDc, Konstantinos Tasoulis, MD, Kostas Charatsis, MD, Giannetopoulos Dimitrios, MD

“…Surgical intervention, particularly microdiscectomy, has shown favorable outcomes in resolving symptoms associated with nerve compression and minimizing recurrence rates. This report presents a case of DEDM in a 39-year-old male with persistent sciatica, analyzing MRI characteristics and surgical treatment.…”
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Respiratory bacterial and viral pathogen spectrum among influenza-positive and influenza-negative patients by Jing Shi, Shi Han, Yating Zhang, Xiaohua Lu, Yunxia Gan, Narenqimuge Tong, Lu Ma, Hang Zhuan, Ying Dai, Yaqi Ji, Guoming Li, Dan Chen, Lu Yang

“…Influenza-positive patients had higher rates of S. pneumoniae and H. influenzae infections, while influenza-negative patients had higher rates of Human parainfluenza viruses and Human rhinoviruses. …”
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Antidepressant Switching as a Proxy Phenotype for Drug Nonresponse: Investigating Clinical, Demographic, and Genetic Characteristics by Chris Wai Hang Lo, Alexandra C. Gillett, Matthew H. Iveson, Michelle Kamp, Chiara Fabbri, Win Lee Edwin Wong, Dale Handley, Oliver Pain, Evangelos Vassos, Naomi R. Wray, Heather C. Whalley, Danyang Li, Allan H. Young, Andrew M. McIntosh, Cathryn M. Lewis

“…Background: Selective serotonin reuptake inhibitors (SSRIs) are a first-line pharmacological therapy in major depressive disorder (MDD), but treatment response rates are low. Clinical trials lack the power to study the genetic contribution to SSRI response. …”
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Long-term outcomes of dupilumab therapy in severe asthma: A retrospective, multicenter, real-world study by Carlo Mümmler, MD, Alexandra Lenoir, MD, Jeremias Götschke, MD, Michael Gerckens, MD, Merle Kaiser, MD, Moritz Kayser, MD, Nora Drick, MD, Hendrik Suhling, MD, Leonie Biener, MD, Carmen Pizarro, MD, Dirk Skowasch, MD, Nikolaus Kneidinger, MD, PhD, Jürgen Behr, MD, Katrin Milger, MD

“…Data on asthma control, medication, lung function, and annualized exacerbation rates were collected at baseline and 3, 12, and 36 months after initiation of dupilumab therapy. …”
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Oncolytic Vaccinia Virus Armed with GM-CSF and IL-7 Enhances Antitumor Immunity in Pancreatic Cancer by Wenyi Yan, Yujing Xuan, Ruimin Wang, Ziyan Huan, Yu Guo, Huilin Dun, Lihua Xu, Ruxia Han, Xianlei Sun, Lingling Si, Nicholas Robert Lemoine, Yaohe Wang, Pengju Wang

“…The synergistic effects of VVL-GL7 and the PD-1 blockade further improved therapeutic outcomes, resulting in significantly higher tumor remission rates compared to monotherapy and achieving complete tumor regression in pancreatic cancer models. …”
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