Epidemiological and Socioeconomic Disparities in the 1742–1743 Epidemic: A Comparative Analysis of Urban Centers and Indigenous Populations Along the Royal Road by Jorge Hugo Villafañe

“…This study assessed excess mortality and socio-economic consequences across different population groups and settlement types. Results: Mortality rates increased dramatically—up to twelve times the pre-epidemic average in Cordova (Córdoba) and by 45% in Santa Fe—disproportionately affecting Indigenous and enslaved populations. …”
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Unraveling the Mechanistic Links Between Species Diversity and Infection Risk From Zoonotic Pathogens With Direct Transmission Among Reservoir Hosts: Rodent‐Orthohantavirus Systems... by Andreas Eleftheriou, Angela D. Luis

“…Although host regulation likely functions via density‐dependent transmission, and can thus change contact rates among hosts, consequences to other mechanisms have been neglected. …”
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Comprehensive multi-omics analysis of histone acetylation modulators identifies ASH1L as a novel aggressive marker for osteosarcoma by Chenlie Ni, Qiwen Sun, Haibo Yin

“…Abstract Background Osteosarcoma, a highly malignant bone tumor prevalent in children and adolescents, continues to have poor long-term survival rates, particularly in metastatic cases. While histone acetylation dysregulation has been implicated in cancer progression, the role of histone acetylation modification-related proteins (HAMRPs) in osteosarcoma immune infiltration and prognosis remains unclear. …”
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Economic growth and urban metamorphosis: A quarter century of transformations within the metropolitan area of Bucharest by Cristian Tosa, Andrei Mitrea, Hitomi Sato, Tomio Miwa, Takayuki Morikawa

“…Lately, these patterns have become manifest in Bucharest as well. …”
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A Data-Driven Analysis of Engineering Contract Risk Characterization Based on Judicial Cases of Disputes by Yongcheng Zhang, Ziyi Wu, Chaohua Xiong, Jianwei Wang, Maxwell Fordjour Antwi-Afari

“…The research identifies contractual risk characteristics across dimensions such as regional distribution, dispute terminology, legal citation patterns, and appellate role transitions. The key findings include the following: (1) Primary risks involve payment disputes, quality assurance failures, contractual validity issues, and schedule compliance challenges. (2) Litigation patterns reveal complex interdependencies between contracting parties and stakeholders, posing significant risk management challenges. (3) High second-instance modification rates stem from procedural irregularities, new evidence, improper legal application, and factual errors in initial trials. …”
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Environmental Factors Driving the Seasonal Dynamics of <i>Ixodes ricinus</i> and <i>Dermacentor reticulatus</i> in Eastern Poland by Aneta Woźniak, Zbigniew Zając, Joanna Kulisz

“…This study investigated their seasonal activity in Eastern Poland, a region with one of the highest incidence rates of tick-borne diseases nationwide. Additionally, we examined tick habitat preferences and the impact of abiotic factors on their activity patterns. …”
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Primary Mediastinal Germ Cell Tumors: A Real-World Analysis of Clinical Characteristics, Treatment, and Survival Outcomes From Two Tertiary Cancer Centers in India by Bharath Gangadhar, Chitrakshi Nagpal, Aparna Sharma, Bivas Biswas, Somnath Roy, Aditya Bhagwat, Deepam Pushpam, Sameer Bakhshi, Sunil Kumar, Kunhi Parambath Haresh, Atul Batra

“…First-line chemotherapy comprised bleomycin, etoposide, and cisplatin (BEP; 60.5%) and etoposide, ifosfamide, and cisplatin (VIP; 27.8%). Response rates included complete response (25.3%) and partial response (54.4%). …”
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Race, gender and stroke subtypes mortality in São Paulo, Brazil Raça, gênero e mortalidade por subtipos da doença cerebrovascular em São Paulo, Brasil by Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor

“…For women, the rates were lower compared to men and the same pattern was observed among Black (125.4), Mixed (88.5) and White (64.1) women. …”
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Contributions of District Health Information Software 2 (DHIS2) to maternal and child health service performance in Ethiopia: an interrupted time series mixed-methods study by Taddese Alemu Zerfu, Moges Asressie, Amare Abera Tareke, Zenebu Begna, Tigist Habtamu, Netsanet Werkneh, Tariku Nigatu, Meskerem Jisso, Addisalem Genta

“…Specifically, DHIS2 led to increased monthly mean performance of key indicators such as antenatal care visits, skilled birth attendance, and immunization rates. Notable improvements in service delivery were observed, with significant increases in institutional delivery rates over time. …”
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Global, regional, and national burdens of traumatic brain injury, spinal cord injury, and skull fracture and their attributable risk factors from 1990 to 2021: a systematic analysi... by Yikang Wang

“…Data were presented as both numerical counts and age-standardized rates (ASRs) per 100,000 population, with corresponding uncertainty intervals. …”
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Analysis of 1560 Inpatient and Outpatient Escherichia coli Isolates from across Canada—Results from the CANWARD 2007 Study by Philippe RS Lagacé-Wiens, Mel DeCorby, Patricia J Baudry, Daryl J Hoban, James A Karlowsky, The Canadian Antimicrobial Resistance Alliance (CARA), George G Zhanel

“…Fluoroquinolones and sulfonamides should be used cautiously and in consideration of local resistance patterns for infections caused by E coli, due to lower susceptibility rates. …”
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Forecast of myocardial infarction incidence, events and prevalence in England to 2035 using a microsimulation model with endogenous disease outcomes. by Peter Scarborough, Asha Kaur, Linda J Cobiac

“…Age-standardised event rates show a similar pattern, with a non-significant upturn by 2035, larger for men than women. …”
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Caregiver substance use among families in the U.S. child welfare system: national prevalence estimates by Susan Yoon, Susan Yoon, Charis Stanek, Juan Lorenzo Benavides, Taylor Napier, Yujeong Chang, Choong Rai Nho

“…Distinct patterns emerged in the prevalence rates of alcohol versus drug dependence across caregiver income, education, employment status, and the number of children’s out-of-home placements.DiscussionOur findings highlight nuanced differences between alcohol and drug dependence and point to the need for targeted and contextually responsive programs that address the complex intersection of caregiver substance use and child maltreatment.…”
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HTLV-1 Japanese subgroup in Brazil: phylogenetic and migratory history by Carolina Amianti, Larissa Melo Bandeira, Aline Pedroso Lorenz, Tayana Serpa Ortiz Tanaka, João Américo Domingos, Ana Rita Coimbra Motta-Castro

“…Abstract Background The retrovirus Human T-lymphotropic virus type 1 is classified into different subtypes, and due to its low evolutionary rates, it can be used to explore geographic patterns of origin and dispersion of human populations. …”
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Spatial distribution of stunting among breast feeding children in Sub-Sahara Africa. by Bekahegn Girma, Lealem Dibku Sasahu, Azizur Rahman

“…In Southern Africa, cold locations like Namibia and South Africa were found to have lower stunting rates.<h4>Conclusion</h4>The significant regional variability in the prevalence of stunting among nursing children in SSA was highlighted by this study. …”
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Parameters for the mathematical modelling of Clostridium difficile acquisition and transmission: a systematic review. by Eroboghene H Otete, Anand S Ahankari, Helen Jones, Kirsty J Bolton, Caroline W Jordan, Tim C Boswell, Mark H Wilcox, Neil M Ferguson, Charles R Beck, Richard L Puleston

“…Forty-nine studies gave recurrence rates of between 3% and 49% but were limited by varying definitions of recurrence. …”
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Sustainable development of mortgage lending: economic challenges and prospects by J.S. Mukhamedov, T.S. Sokira, Z. Kuldasheva

“…As a result, a forecasting model was developed, incorporating GDP growth, lending interest rates, and the level of non-performing loans as independent variables. …”
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THE RELEVANCE OF A COMPREHENSIVE ANALYSIS OF MEDICAL AND DEMOGRAPHIC PROBLEMS IN CONNECTION WITH THE HARMFUL EFFECTS ON HUMANS OF ENVIRONMENTAL FACTORS IN KUZBASS by Андрей Георгиевич Петров, Виктор Андреевич Семенихин, Ольга Владимировна Хорошилова, Сергей Николаевич Филимонов, Юлия Александровна Сашко

“…In Kuzbass, in comparison with the Russian Federation, the mortality rates of the population are higher and life expectancy is lower, and there are higher mortality rates of the population from most of the most common causes of death than in the Russian Federation. …”
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Spatial analysis of under-five mortality in Africa using geographically weighted poisson regression by Johnson Adedeji Olusola, Adedeji Adigun Oyinloye, Kemi F. Akeju, Ropo Ebenezer Ogunsakin, Sibusiso Moyo

“…The disparities in child mortality rates can be attributed to socioeconomic and environmental inequalities across nations. …”
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Investigation of the effect of deprivation on the burden and management of venous leg ulcers: a cohort study using the THIN database. by Emily S Petherick, Nicky A Cullum, Kate E Pickett

“…<h4>Background</h4>There has been limited examination of the contribution of socio-economic factors to the development of leg ulcers, despite the social patterning of many underlying risk factors. No previous studies were found that examined social patterns in the quality of treatment received by patients with leg ulcers.…”
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