Individualized Estimation of Baseline Retinal Nerve Fiber Layer Thickness Using Conditional Variational Autoencoder by Ou Tan, PhD, Keke Liu, MD, Aiyin Chen, MD, Dongseok Choi, PhD, Jonathan C.H. Chan, MD, Bonnie N.K. Choy, MD, Kendrick C. Shih, MD, Jasper K.W. Wong, MD, Alex L.K. Ng, MD, Janice J.C. Cheung, MD, Michael Y. Ni, MD, Jimmy S.M. Lai, MD, Gabriel M. Leung, MD, Ian Y.H. Wong, MD, David Huang, MD, PhD

“…Compared with the population means, both DL models significantly reduced the prediction error for overall and quadrant NFLT and decreased the false-positive rate of identifying abnormal NFLT thinning in both myopia groups (from 13.0%-27.0% to 6.3%∼9.4%). …”
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Dual‐Responsive Multi‐Functional Silica Nanoparticles With Repaired Mitochondrial Functions for Efficient Alleviation of Spinal Cord Injury by Guibin Gao, Juanjuan Li, Yanming Ma, Min Xie, Jianxian Luo, Ke Wang, Cheng Peng, Hua Yang, Tianjun Chen, Guowei Zhang, Jiang Ouyang, Hongsheng Lin, Zhisheng Ji

“…This nanosystem increased the stability of NADH during prolonged blood circulation time, reduced the clearance rate, exhibited significant anti‐inflammatory as well as neuroprotective effects and enhanced the regeneration of electrophysiological conduction capacity across SCI areas. …”
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Optimizing fertilizer application and straw return to fields to minimize nitrogen and phosphorus runoff losses in double-rice cropping systems by Ying Zhang, Jian Zhu, Changjun Li, Hua Peng, Ji Liu, Yue Luo, Min Song, Yanjiao Dai, Kai Deng, Xionghui Ji

“…Unknown of long-term patterns of losses and mechanisms driving runoff N and P in double-rice cropping systems limited the development of effective mitigation strategies. …”
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Therapeutic Effects of Forest Bathing on Human Health: A Systematic Review by Adrianna Samoraj, Jakub Zajączkowski, Paulina Krzeszowska, Kacper Stępniak, Karolina Marrodán-Wojtczak, Jan Wilk, Jakub Jarmołowicz, Aleksandra Kujawa, Karolina Krochmal, Radosław Kuźma

“…Specifically, a reduction in heart rate, as well as systolic and diastolic blood pressure, was observed in individuals who participated in forest excursions.  …”
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Clinical Presentation, Pathological Spectrum, and Outcomes of Alcoholic Cirrhosis-Related Immunoglobulin A Nephropathy by Charles Ronsin, Pierre Braud, Christine Kandel-Aznar, Amaury Dujardin, Clémence Petit, David Larmet, Claire Garandeau, Clément Deltombe, Alice Le Clech, Claire Leman, Gilles Blancho, Juliet Schurder, Grégoire Couvrat-Desvergnes, Simon Ville

“…The cumulative mortality rate in cirrhosis-IgAN was 26% and 46% at 1-year and 3-years, respectively. …”
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Global stroke burden attributable to household air pollution: Insights from GBD 2021 and projections to 2040. by Manqing Li, Shicheng Liao, Chao Wang, Haojia Ma, Xiumei Xing, Jianhui Yuan, Jie Jiang, Zhuoying Zeng

“…From 1990-2021, age-standardized death rates (EAPC = -0.37), DALY rates (EAPC = -0.20), and YLL rates (EAPC = -0.30) decreased, while YLD rates increased (EAPC = 1.11). …”
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Influence of the extent of cervical lymph node dissection and lymph nodes metastases on prognosis in a cohort of dogs with oral malignant melanoma treated by surgical resection and... by Davide Giacobino, Matteo Olimpo, Erica Ilaria Ferraris, Greta Martinelli, Lorella Maniscalco, Mariateresa Camerino, Federica Riccardo, Federica Cavallo, Lidia Tarone, Marzia Cino, Alfredo Dentini, Selina Iussich, Elena Lardone, Luca Manassero, Raffaella De Maria, Paolo Buracco, Emanuela Morello

“…The overall LN metastatic rate was 31%; metastasis was found mostly in the mandibular lymph center (83%). …”
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Prolyl 4-hydroxylase subunit alpha-2 acts as a TRIM21 ubiquitination substrate to promote papillary thyroid cancer progression via the glycolytic pathway by Fengping Wu, Qian Liu, Jinkang Zhang, Dongkun Xu, Xue Jiang, Kun Zhang, YaZheng Chen, Xuliang Xia, Zhiqiang Jiang, Yuhong Shi, Wenling Tu

“…This study explored the expression pattern, functional role, and underlying molecular mechanism of P4HA2 in PTC. …”
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Diagnostic work-up of anemia and associated health outcomes in people with heart failure by Guobin Su, Ruowei Xiao, Dongze Ji, Kaiyu He, Anna Hallert, Gianluigi Savarese, Lars H. Lund, Yang Xu, Juan Jesus Carrero

“…Time-varying Cox regression explored associations between developing anemia and rate of major adverse cardiovascular events (MACE), HF hospitalization, cancer, and death. …”
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Analysis of Age-related Changes of Characteristics and High Frequency Symptoms in Pre-elderly and Elderly Inpatients by YUE Xiao, WANG Mei

“…Conclusion The incidence of symptoms in pre-elderly and elderly inpatients shows an overall increasing trend with age, and the rate of age-related changes varies for different symptoms. …”
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Comparison of impact of various application methods for the blood plasm, enriched by the thrombocytes, on healing of the burn and scalped wounds in experiment by G. V. Terehov, O. A. Hyndych, І. M. Savytska, M. V. Kostylev, E. V. Symulyk, M. V. Chukhraiev

“…To the investigation Group II animals the electrophoresis in accordance to own procedure through napkin, soaked in the blood plasm, enriched by thrombocytes, was performed with the same rate. The blood plasm, enriched by thrombocytes, was prepared from the whole venous blood of human Group A(0), using centrifugation for achievement of targeted quantity of thrombocytes 850 000 in 1 ml. …”
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Miotonia congênita: relato de sete pacientes Congenital myotonia: report of seven patients by Helga C. A. Azevedo, Lúcia I. Z. Mendonça, Paulo N. B. Salum, Mary S. Carvalho, Sueli K. Nagahashi-Marie, Alzira A. Siqueira-Carvalho, Maria A. Cerqueira, Umbertina C. Reed, José A. Levy

“…<br>Myotonia is the phenomenon of decrease of muscular relaxation rate, after either a contraction or a mechanical or electrical stimulus. …”
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Assessment of the Impacts of Different Carbon Sources and Sinks on Atmospheric CO₂ Concentrations Based on GEOS-Chem by Ge Qu, Jia Zhou, Yusheng Shi, Yongliang Yang, Mengqian Su, Wen Wu, Zhitao Zhou

“…The global average CO₂ concentration increased by 1.8 ppm year⁻¹ from 2006 to 2010, with China’s eastern region experiencing the highest growth rate of 3.0 ppm year⁻¹. Fossil fuel combustion is identified as the largest CO₂ emission source, followed by biomass burning, while oceans and land serve as significant CO₂ sinks. …”
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Anticancer properties of copolymer nanoparticles loaded with Foeniculum vulgare derivatives in Hs578T and SUM159 cancer cell lines by Shima Bourang, Sodabeh Jahanbakhsh Godehkahriz, Mehran Noruzpour, Rasool Asghari Zakaria, Sergio Granados-Principal

“…Moreover, the drug release pattern illustrated a higher release rate from synthesized nanoparticles under acidic conditions (pH = 5). …”
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Genome-wide associations spanning 194 in-hospital drug dosage change phenotypes highlight diverse genetic backgrounds in concurrent drug therapy by Alexander Pil Henriksen, Cristina Leal Rodríguez, Hannah Currant, Ioannis Louloudis, Jorge Hernansanz Biel, Maria Herrero-Zazo, Ewan Birney, Thomas Folkmann Hansen, Gianluca Mazzoni, Amalie Dahl Haue, Henning Bundgaard, Christian Erikstrup, Khoa Manh Dinh, Liam Quinn, Mie Topholm Bruun, Henrik Hjalgrim, Erik Sørensen, Christina Mikkelsen, Michael Schwinn, Ole Birger Vestager Pedersen, Henrik Ullum, Sisse Rye Ostrowski, Karina Banasik, Søren Brunak

“…As populations get older and medicine consumption rises, the rate of concurrent drug use and polypharmacy among patients is increasing. …”
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Epidemiological characterization of chronic myeloid leukaemia patients at an oncologic centre: A retrospective observational study by Ana Maria Meireles, Rita Calisto, Maria José Bento, Pedro Martinho Gouveia, Susana Bizarro, Manuel Teixeira, Cláudia Moreira, Ana Espírito Santo, Mário Mariz

“…At three months, the early molecular response rate was 77 %. At 12 months of treatment, of the 67 patients with response evaluation, 93 % achieved complete cytogenetic response and 49 % major molecular response. …”
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COVID-19 vaccine evidence monitoring assisted by artificial Intelligence: An emergency system implemented by the Public Health Agency of Canada to capture and describe the trajecto... by Su Hyun Lim, Mona Hersi, Ramya Krishnan, Joshua Montroy, Bonnie Rook, Kelly Farrah, Yung-En Chung, Adrienne Stevens, Joseline Zafack, Eva Wong, Nicole Forbes, April Killikelly, Kelsey Young, Matthew Tunis

“…Analysis of COVID-19 vaccine research patterns supports projections of research volume, type, and rate that will help predict resourcing and information needs to plan future emergency vaccine guidance activities.…”
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Leveraging a disulfidptosis-based signature to characterize heterogeneity and optimize treatment in multiple myeloma by Bingxin Zhang, Dong Zheng, Shuxia Zhu, Xinyi Zhang, Quanqiang Wang, Zhili Lin, Ziwei Zheng, Shujuan Zhou, Zixing Chen, Sisi Zheng, Enqing Lan, Luning Cui, Hansen Ying, Yu Zhang, Xuanru Lin, Qiang Zhuang, Honglan Qian, Xudong Hu, Yan Zhuang, Qianying Zhang, Zhouxiang Jin, Songfu Jiang, Yongyong Ma, Yongyong Ma, Yongyong Ma

“…Multiple myeloma (MM) is the second most prevalent hematologic malignancy characterized by a high synthesis rate of disulfide bond-rich proteins and chronic oxidative stress. …”
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Discovery and molecular identification of a new orthophasmavirus in the Asian citrus psyllid (Diaphorina citri) by Song Zhang, Song Zhang, Jing Chen, Jing Chen, Luqin Liu, Luqin Liu, Zhipeng Xie, Zhipeng Xie, Jiamei Liang, Jiamei Liang, Fulin Yan, Fulin Yan, Yaqin Song, Xuefeng Wang, Xuefeng Wang, Changyong Zhou, Changyong Zhou, Mengji Cao, Mengji Cao, Jinxiang Liu, Jinxiang Liu

“…It was also detected in progeny of infected ACPs and in the leaves fed upon by infected individuals. The infection rate of CLas was reduced in ACPs infected with DcBV2, and vice versa.DiscussionDcBV2 was fully sequenced and represents a new Orthophasmavirus species. …”
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Widespread geographic distribution of filarioid nematodes in caribou (Rangifer tarandus sspp.) in Canada by Aparna Mariyam Thomas, Guilherme G. Verocai, John Soghigian, Fabien Mavrot, Naima Jutha, Jan Adamczewski, Tracy Davison, Gwen Duytschaever, Arthur Fernandes, Allicia Kelly, Matthew R. Kulpa, Eve Lamontagne, Lisa-Marie Leclerc, Sara McCarthy, Ashley McLaren, Amanda D. Melin, Susan J. Kutz

“…The Arctic is currently experiencing an unprecedented rate of climate change, including warming temperatures and altered patterns of precipitation. …”
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