Integrative single‐cell transcriptomic analysis deciphers heterogeneous characteristics of gastrointestinal tract cancer by Chuwen Sun, Tong Li, Xin Jin, Zhihui Xiu, Hang Su, Huanming Yang, Ming Liu, Kui Wu

“…Abstract Background Gastrointestinal tract cancer (GIC), including oesophageal cancer (EC), gastric cancer (GC) and colorectal cancer (CRC), is characterised with high global incidence and mortality rates, with similar tumourigenic processes. However, the common and heterogeneous molecular features among GIC at single‐cell level remain poorly characterised. …”
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Pitfalls in the diagnosis of apparent homozygous mutations: two cases of IL10RA deficiency inflammatory bowel disease and a literature review by Xiu Shi, Ziqing Ye, Lai Qian, Wenhui Hu, Ye Yang, Chunmeng He, Zhiheng Huang, Bingbing Wu, Ying Huang

“…Abstract Background In East Asia, IL10RA is the predominant pathogenic gene in patients with very early-onset inflammatory bowel disease (VEO-IBD), frequently characterised by refractory diarrhoea and severe perianal disease, resulting in elevated death rates. IL10RA-deficient IBD, an autosomal recessive genetic disorder, has been documented to be inherited through the conventional compound heterozygous or homozygous mutation patterns from both parents. …”
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The global burden of chronic kidney disease due to diabetes mellitus type 2 attributable to diet high in sugar-sweetened beverages among the elderly: a comprehensive analysis from... by Ben Hu, Ben Hu, Xiaohan Qiu, Zhengbiao Luo, Zhengbiao Luo, Jingxiong Chen, Jun Feng, Jun Feng, Linlin Hou, Linlin Hou

“…However, the global burden of CKD-T2DM attributable to high SSB consumption among elderly populations remains poorly characterized.MethodsUsing data from the Global Burden of Disease Study 2021, we examined age-standardized mortality rates (ASMR) and disability-adjusted life year rates (ASDR) of CKD-T2DM attributable to high SSB consumption among individuals aged 60 years and older across 204 countries and territories from 1990 to 2021. …”
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Association between ECG Abnormalities and Hookah and Cigarette Smoking in the MASHAD Cohort Study Subjects by Maryam Mohammadi-Bajgiran, Reyhaneh Saffar-Khorasani, Muhammad Islampanah, Reza Nejad Shahrokh Abadi, ‌Bahram Shahri, Sara Saffar Soflaei, Souren Nemati-Khorasani, Habibollah Esmaily, Gordon Ferns, Mohsen Moohebati, Majid Ghayour-Mobarhan

“…Cigarette users (92.3% male) had significantly lower BMI and higher employment rates compared to non-smokers, whereas hookah smokers (90.2% female) had higher BMIs and were predominantly retirees. …”
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Tobacco smoking and smokeless tobacco use among people living with HIV in Zambia: Findings from a 2023 National NCD/HIV Survey. by Cosmas Zyambo, Paul Somwe, Chomba Mandyata, Mwiche Musukuma, Phoebe Bwembya, Henry Phiri, Malizgani P Chavula, Hikabasa Halwindi, Joseph Zulu, Wilbroad Mutale

“…Tobacco smoking, SLT use, behavioral patterns, and clinical characteristics were assessed. …”
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Cancelable Multi-Branch Deep Learning Framework for Privacy-Preserving ECG Biometric Authentication by Mohamed Hammad, Ali Abdullah S. AlQahtani, Mohammed ELAffendi, Abdelhamied A. Ateya, Nebojsa Bacanin

“…We evaluate the framework on two publicly available ECG datasets (PTB and ECG-ID) achieving high authentication performance with accuracies of 96.25% and 96.43%, respectively, and Equal Error Rates (EER) of 3.55% and 3.6%. The system meets critical privacy-preserving criteria, including irreversibility, unlinkability, diversity, and revocability. …”
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Evaluating the Effects of Mitigating Urban Heat Islands of Green Infrastructure on Increasing the Productivity of Light and Heavy Work (Case Study: Tabriz Metropolitan) by Mahdi Herischian, Hassan Mahmoudzadeh, Rasoul Ghorbani

“…The primary inputs for the model included a land use/land cover raster map, a reference evapotranspiration (ET0) raster map, a biophysical table containing details about each land use/land cover class, a vector map of city buildings, and an energy consumption rate table categorized by building type and air temperature. …”
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Evolutionary trajectory estimation via replication simulation of coronavirus spike gene based on random mutation and similarity-based selection by Min Chan Kim, Hye Ji Jung, Seong Sik Jang, Van Thi Lo, Hye Kwon Kim

“…Simulations tracking the evolution of SARS-CoV-2 Wuhan-Hu-1 toward the Omicron variant (BA.1) displayed plateau-like similarity trajectories, where increased substitution rates resulted in a more rapid attainment of the plateau stage. …”
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A neuronal imaging dataset for deep learning in the reconstruction of single-neuron axons by Liya Li, Liya Li, Ying Hu, Ying Hu, Xiaojun Wang, Pei Sun, Tingwei Quan

“…Our results demonstrate significantly improved axon detection rates across both state-of-the-art and traditional methodologies. …”
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Deep Learning Approach for Classifying DDoS Attack Traffic in SDN Environments by Mohd Nadeem, Shweta Dwivedi, Rizwan Akhtar, Shameem Ahmad Ansari, Saumya Singh, Eram Fatima Siddiqui, Rajeev Kumar

“…A neural network classifier analyzes this data to identify complex patterns and behaviors associated with DDoS attacks. …”
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First Molecular Characterization and Antibiogram of Bacteria Isolated From Dairy Farm Wastewater in Bangladesh by Md. Shamsul Islam, Md. Arif-Uz-Zaman Polash, Md. Hakimul Haque

“…Moreover, several antibiotic resistance genes (ARGs) including penA, blaTEM, blaCTX−M, tetA, tetB, tetC, and ermB were detected across the bacterial species, with high prevalence rates in P. aeruginosa and A. junii, suggesting the potential for horizontal gene transfer and further spread of resistance. …”
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Association of Paternal Diabetes With Hemorrhagic Stroke in Bangladeshi Women: The MAGPIE Study by Md. Abdullah Yusuf, Redoy Ranjan, Dipannita Adhikary, Adneen Moureen, Maliha Hakim

“…Although males had significantly higher rates of hypertension (p < 0.001), diabetes (p = 0.008), chronic constipation (p = 0.03), and systolic blood pressure (p < 0.001), females were found to have significantly higher body mass index (23.1 ± 3.1 vs. 21.4 ± 2.9; p < 0.001) and paternal diabetes (9.6% vs. 4.8%; p = 0.004) compared to male. …”
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Graph Neural Network With Hessian-Based Locally Linear Embedding for Cancer Metastasis Analysis in Lymph Nodes Using DeepLab Segmentation by Senthil Jayapal, R. Annamalai

“…In clinical settings, where whole-slide images of histological lymph nodes are involved, it is crucial to identify and detect breast cancer metastases. Patient survival rates increase significantly with early detection. …”
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Comparative analysis of aggressiveness in giant cell tumor of bone between upper and lower extremities: A systematic review and meta-analysis by Rhyan Darma Saputra, Dita Anggara Kusuma, Fathih Kaldani, Khoirul Fahmi

“…Emerging evidence suggests unique behavioral patterns of GCTB in extremities. This study seeks to rigorously compare the aggressiveness of GCTB in the upper versus lower extremities, centering on recurrence rates. …”
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Treatment outcomes of bedaquiline-based longer oral antitubercular regimens in Indian children above five years of age by Ira Shah, Dhruv N. Gandhi, Ramsha Ansari, Himanshu Warse, Sachi Kalawadia, Tsering Yangchen, Daksha Shah, Varsha Puri, Sanjay Mattoo, Minnie Bodhanwala

“…Conclusion: BDQ-based regimens are effective in treating pediatric DR-TB, with high treatment completion rates. However, the duration of treatment is 18 months or longer in most patients based on clinico-radiological resolution. …”
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Prevalence and Associated Factors of Insomnia in Adult Psychiatric Patients: A Hospital-Based Study by Jhowhar Datta, Mohammad Tariqul Alam, Taiyeb Ibna Zahangir, Sadia Afrin, Ahsan Aziz Sarkar, Md Shariful Haque, A. M. Fariduzzaman, Bijoy Kumar Dutta

“…Results The prevalence of insomnia was 44.2%, with the highest rates observed in trauma-and stressor-related disorders, followed by depressive disorders. …”
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Epidemiology of extended-spectrum β-lactamase producing Escherichia coli from hospital settings in Yemen by Samar Nasher, Sameer Alsharapy, Anwar Al-Madhagi, Fathiah Zakham

“…The highest significant rates were among the elderly, patients with previous hospitalization, patients who have stayed in hospital more than 22 days, patients who have taken third generation cephalosporins as treatment and diabetic patients. …”
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Social media use, risk behavior engagement, and mental health among middle adolescents in the Caribbean by Deogwoon Kim, Riley Magane, Maxwell Poitier, Julia Kuang, Ava Wang, Richard Adderley, Lynette Deveaux

“…Girls reported higher rates of social media usage, active and passive engagement on social media, cyberbullying experiences, and mental health issues, while boys were more likely to engage in sexting and offline risk behaviors. …”
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MSDCA: A Multi-Scale Dual-Branch Network with Enhanced Cross-Attention for Hyperspectral Image Classification by Ning Jiang, Shengling Geng, Yuhui Zheng, Le Sun

“…First, a multiscale 3D spatial–spectral feature extraction module (3D-SSF) employs parallel 3D convolutional branches with diverse kernel sizes and dilation rates, enabling hierarchical modeling of spatial–spectral representations from large-scale patches and effectively capturing both fine-grained textures and global context. …”
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Non-selective waterbird hunting in a Natura 2000 site results in killing of protected species: A case study from western Poland by Dominik Marchowski, Robert Jurszo, Paweł Stańczak, Michał Jasiński, Sebastian Guentzel

“…For nearly all species, harvest rates exceeded the sustainable thresholds defined by BirdLife International. …”
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