Experimental Reconstruction of a Nineteenth Century Lower Limb Prosthetic Peg Leg – The Box Leg by Charlotte Waller-Cotterhill

“…However, that all societies (past and present) follow a single technological trajectory just at different rates of progress would be an inaccurate assumption (Pfaffenberger, 1992). …”
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Decoding Phthorimaea operculella (Lepidoptera: Gelechiidae) in the new age of change by Silvia I. RONDON

“…Scenarios of climate variation have increased the possibility of changes in pests' biological and ecological patterns by increasing or reducing overwintering length, changes in population growth rates, number of generations, crop-pest relationship, and therefore affecting their expansion. …”
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Targeted screening and single-cell analysis of genetic variants in melanoma using Mendelian randomization by Shi Li, Kaijiong Zhang, Guiji Zhang, Min Shi, Xing Yin, Bo Wang

“…Methods We combined SNP data from GTEx V8 eQTL and FinnGen databases for Mendelian randomization analysis, and performed single-cell analysis on melanoma samples. Results Melanoma rates were higher in men than women and increased with age. …”
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Parsimonious and explainable machine learning for predicting mortality in patients post hip fracture surgery by Fouad Trad, Bassel Isber, Ryan Yammine, Khaled Hatoum, Dana Obeid, Mohammad Chahine, Rachid Haidar, Ghada El-Hajj Fuleihan, Ali Chehab

“…Abstract Hip fractures among the elderly population continue to present significant risks and high mortality rates despite advancements in surgical procedures. …”
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Primary Mediastinal Germ Cell Tumors: A Real-World Analysis of Clinical Characteristics, Treatment, and Survival Outcomes From Two Tertiary Cancer Centers in India by Bharath Gangadhar, Chitrakshi Nagpal, Aparna Sharma, Bivas Biswas, Somnath Roy, Aditya Bhagwat, Deepam Pushpam, Sameer Bakhshi, Sunil Kumar, Kunhi Parambath Haresh, Atul Batra

“…First-line chemotherapy comprised bleomycin, etoposide, and cisplatin (BEP; 60.5%) and etoposide, ifosfamide, and cisplatin (VIP; 27.8%). Response rates included complete response (25.3%) and partial response (54.4%). …”
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Epidemiological and Socioeconomic Disparities in the 1742–1743 Epidemic: A Comparative Analysis of Urban Centers and Indigenous Populations Along the Royal Road by Jorge Hugo Villafañe

“…This study assessed excess mortality and socio-economic consequences across different population groups and settlement types. Results: Mortality rates increased dramatically—up to twelve times the pre-epidemic average in Cordova (Córdoba) and by 45% in Santa Fe—disproportionately affecting Indigenous and enslaved populations. …”
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Unraveling the Mechanistic Links Between Species Diversity and Infection Risk From Zoonotic Pathogens With Direct Transmission Among Reservoir Hosts: Rodent‐Orthohantavirus Systems... by Andreas Eleftheriou, Angela D. Luis

“…Although host regulation likely functions via density‐dependent transmission, and can thus change contact rates among hosts, consequences to other mechanisms have been neglected. …”
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A Data-Driven Analysis of Engineering Contract Risk Characterization Based on Judicial Cases of Disputes by Yongcheng Zhang, Ziyi Wu, Chaohua Xiong, Jianwei Wang, Maxwell Fordjour Antwi-Afari

“…The research identifies contractual risk characteristics across dimensions such as regional distribution, dispute terminology, legal citation patterns, and appellate role transitions. The key findings include the following: (1) Primary risks involve payment disputes, quality assurance failures, contractual validity issues, and schedule compliance challenges. (2) Litigation patterns reveal complex interdependencies between contracting parties and stakeholders, posing significant risk management challenges. (3) High second-instance modification rates stem from procedural irregularities, new evidence, improper legal application, and factual errors in initial trials. …”
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PathCare: Integrating Clinical Pathway Information to Enable Healthcare Prediction at the Neuron Level by Dehao Sui, Lei Gu, Chaohe Zhang, Kaiwei Yang, Xiaocui Li, Liantao Ma, Ling Wang, Wen Tang

“…PathCare employs an auxiliary sub-network that models future visit patterns to capture temporal health progression, coupled with a neuron-level filtering gate that adaptively selects relevant features while filtering out redundant information. …”
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Race, gender and stroke subtypes mortality in São Paulo, Brazil Raça, gênero e mortalidade por subtipos da doença cerebrovascular em São Paulo, Brasil by Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor

“…For women, the rates were lower compared to men and the same pattern was observed among Black (125.4), Mixed (88.5) and White (64.1) women. …”
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Contributions of District Health Information Software 2 (DHIS2) to maternal and child health service performance in Ethiopia: an interrupted time series mixed-methods study by Taddese Alemu Zerfu, Moges Asressie, Amare Abera Tareke, Zenebu Begna, Tigist Habtamu, Netsanet Werkneh, Tariku Nigatu, Meskerem Jisso, Addisalem Genta

“…Specifically, DHIS2 led to increased monthly mean performance of key indicators such as antenatal care visits, skilled birth attendance, and immunization rates. Notable improvements in service delivery were observed, with significant increases in institutional delivery rates over time. …”
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Global, regional, and national burdens of traumatic brain injury, spinal cord injury, and skull fracture and their attributable risk factors from 1990 to 2021: a systematic analysi... by Yikang Wang

“…Data were presented as both numerical counts and age-standardized rates (ASRs) per 100,000 population, with corresponding uncertainty intervals. …”
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Forecast of myocardial infarction incidence, events and prevalence in England to 2035 using a microsimulation model with endogenous disease outcomes. by Peter Scarborough, Asha Kaur, Linda J Cobiac

“…Age-standardised event rates show a similar pattern, with a non-significant upturn by 2035, larger for men than women. …”
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Analysis of 1560 Inpatient and Outpatient Escherichia coli Isolates from across Canada—Results from the CANWARD 2007 Study by Philippe RS Lagacé-Wiens, Mel DeCorby, Patricia J Baudry, Daryl J Hoban, James A Karlowsky, The Canadian Antimicrobial Resistance Alliance (CARA), George G Zhanel

“…Fluoroquinolones and sulfonamides should be used cautiously and in consideration of local resistance patterns for infections caused by E coli, due to lower susceptibility rates. …”
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HTLV-1 Japanese subgroup in Brazil: phylogenetic and migratory history by Carolina Amianti, Larissa Melo Bandeira, Aline Pedroso Lorenz, Tayana Serpa Ortiz Tanaka, João Américo Domingos, Ana Rita Coimbra Motta-Castro

“…Abstract Background The retrovirus Human T-lymphotropic virus type 1 is classified into different subtypes, and due to its low evolutionary rates, it can be used to explore geographic patterns of origin and dispersion of human populations. …”
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Sustainable development of mortgage lending: economic challenges and prospects by J.S. Mukhamedov, T.S. Sokira, Z. Kuldasheva

“…As a result, a forecasting model was developed, incorporating GDP growth, lending interest rates, and the level of non-performing loans as independent variables. …”
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THE RELEVANCE OF A COMPREHENSIVE ANALYSIS OF MEDICAL AND DEMOGRAPHIC PROBLEMS IN CONNECTION WITH THE HARMFUL EFFECTS ON HUMANS OF ENVIRONMENTAL FACTORS IN KUZBASS by Андрей Георгиевич Петров, Виктор Андреевич Семенихин, Ольга Владимировна Хорошилова, Сергей Николаевич Филимонов, Юлия Александровна Сашко

“…In Kuzbass, in comparison with the Russian Federation, the mortality rates of the population are higher and life expectancy is lower, and there are higher mortality rates of the population from most of the most common causes of death than in the Russian Federation. …”
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Spatial analysis of under-five mortality in Africa using geographically weighted poisson regression by Johnson Adedeji Olusola, Adedeji Adigun Oyinloye, Kemi F. Akeju, Ropo Ebenezer Ogunsakin, Sibusiso Moyo

“…The disparities in child mortality rates can be attributed to socioeconomic and environmental inequalities across nations. …”
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Investigation of the effect of deprivation on the burden and management of venous leg ulcers: a cohort study using the THIN database. by Emily S Petherick, Nicky A Cullum, Kate E Pickett

“…<h4>Background</h4>There has been limited examination of the contribution of socio-economic factors to the development of leg ulcers, despite the social patterning of many underlying risk factors. No previous studies were found that examined social patterns in the quality of treatment received by patients with leg ulcers.…”
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Prevalence and predictors of substance use as a factor in suicide in the USA, 2015–2020: a repeated cross-sectional analysis by Julie A Phillips

“…Background US rates of substance abuse and suicide mortality increased dramatically in recent years, but little is known about how rising rates of drug and alcohol use are associated with suicide. …”
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