Major Traumatic Injury and Exposure to Mitochondrial-Derived Damage-Associated Molecular Patterns Promotes Neutrophil Survival Accompanied by Stabilisation of the Anti-Apoptotic Pr... by Thomas Nicholson, Michael Macleod, Antonio Belli, Janet M. Lord, Jon Hazeldine

“…Culturing HCs neutrophils with mtDAMPs or mtDNA significantly delayed apoptosis rates, promoted stabilisation of Mcl-1, and reduced caspase-3 activation. …”
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Nosocomial transmission, adaption and clinical outcomes of carbapenem-resistant hypervirulent Klebsiella pneumoniae by Yanjun Liu, Zhiqian Wang, Zijuan Jian, Peilin Liu, Yanming Li, Fang Qin, Qun Yan, Wenen Liu

“…CR-HvKp infections were significantly associated with higher mortality rates, especially involved in sepsis or septic shock (P < 0.0001). …”
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Survival benefits of primary tumor resection in metastatic differentiated thyroid cancer: an analysis of SEER data by Jiaqiang Dan, Jingya Tan, Yao Guo, Xin Lu, Ying Leng, Renxi Tang, Junyan Li, Junhua Huang

“…Abstract Metastatic differentiated thyroid cancer (mDTC) can exhibit aggressive growth and disseminate to distant organs, thereby reducing survival rates. The benefits of primary tumor resection (PTR) for patients with mDTC are still debated. …”
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Patterns and Predictors of <i>Candida auris</i> Candidemia with Multidrug-Resistant Bacterial Co-Infections: Results from the CANDI-MDR Study by Karolina Akinosoglou, Katerina Skintzi, Ioannis Chandroulis, Eleni Polyzou, Argiro Siapika, Foteini Fligkou, Fotini Paliogianni, Charalambos Gogos, George Dimopoulos

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Identifying patterns of high intraoperative blood pressure variability in noncardiac surgery using explainable machine learning: a retrospective cohort study by Zheng Zhang, Jian Wu, Yi Duan, Linwei Liu, Yaru Liu, Jinghan Wang, Li Xiao, Zhifeng Gao

“…Intraoperative average heart rate (HR) and bispectral index (BIS) were the most influential variables. …”
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Hospitalizations trends and co-infection patterns for respiratory virus infections in children in central China 2015 to 2023: a longitudinal surveillance study by Bowen Dai, Chong Chen, Yuanfang Shen, Shouhang Chen, Ruyu Zhang, Chenyu Wang, Jiaying Zheng, Qiujing Liang, Qingmei Wang, Yaodong Zhang, Yuefei Jin, Fang Wang, Zhi Li

“…A significantly higher detection rate was observed in males compared to females (57.22% vs. 42.78%; χ2 < 0.001). …”
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FPGA Implementation for 24.576-Gbit/s Optical PAM4 Signal Transmission with MLP-Based Digital Pre-Distortion by Sheng Hu, Tianqi Zheng, Chengzhen Bian, Xiongwei Yang, Xinda Sun, Zonghui Zhu, Yumeng Gou, Yuanxiao Meng, Jie Zhang, Jingtao Ge, Yichen Li, Kaihui Wang

“…At the receiver, the parallel constant modulus algorithm (PCMA) was applied for signal processing. The bit error rate (BER) achieved met the 2.4 × 10⁻² threshold for soft-decision forward error correction (SD-FEC), enabling a net transmission bit rate of 24.576 Gbit/s. …”
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Epidemiological perspectives of amyloidosis in Argentina: a cohort study analysing incidence and mortality patterns among a population affiliated to a medical care programme by María Lourdes Posadas-Martínez, Delfina Cirelli, Florencia De Florio, María Adela Aguirre, Elsa Mercedes Nucifora, Patricia Beatriz Sorroche, María Soledad Sáez, Valeria Inés Aliperti, Jimena Vicens, Marcelina Carretero

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Fertility Counseling Pattern over Time in Young Patients with Breast Cancer: A Retrospective Analysis at a Large Comprehensive Cancer Center by Caterina Barbieri, Ottavia Amato, Anna Chiara Cattelan, Loris Marin, Alessandra Andrisani, Carlo Saccardi, Tommaso Giarratano, Giovanni Faggioni, Elisabetta Di Liso, Carlo Alberto Giorgi, Eleonora Mioranza, Cristina Falci, Grazia Maria Vernaci, Roberto Tozzi, Valentina Guarneri, Maria Vittoria Dieci

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Epidemiological Trends and Drug Resistance Patterns of Carbapenem-Resistant Gram-Negative Bacteria: A Retrospective Study in a Tertiary Hospital in China (2019-2024) by Hou B, Niu X, Yu Q, Wang W

“…In 2021, notable shifts in hospital infection control concerning CR-GNB were observed, with a reduction of over 40% in CRAB infection rates and a decline of over 35% in CRPA infection rates. …”
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Analyzing Medication Adherence Patterns Among Type 2 Diabetes Patients in Thi-Qar, Iraq: A Cross-Sectional Study by Adel Gassab Mohammed, Nassar Taha Yaseen, Dheyaa K. AlWaeli

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Outcomes and vaccination patterns against COVID-19 in a cohort of sickle cell disease patients in the state of Rio de Janeiro by Claudia de Alvarenga Maximo, Jorge Francisco da Cunha Pinto, Fabiana Canedo Pinto, Patrícia Brasil

“…Sociodemographic data, emergency department visits, hospitalizations, mortality rates, and COVID-19 vaccination status were collected. …”
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Resistance Patterns of <i>Neisseria gonorrhoeae</i> in PLHIV: A Cross-Sectional Study from the Republic of Cyprus, 2015–2023 by Michaela Takos, George Siakallis, Annalisa Quattrocchi, Maria Alexandrou, Panagiota Papadamou, Loukia Panagiotou, Danny Alon-Ellenbogen

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Spatial patterns and clustering of dengue incidence in Mexico: Analysis of Moran's index across 2,471 municipalities from 2022 to 2024. by Oliver Mendoza-Cano, Rogelio Danis-Lozano, Xóchitl Trujillo, Miguel Huerta, Mónica Ríos-Silva, Agustin Lugo-Radillo, Jaime Alberto Bricio-Barrios, Verónica Benites-Godínez, Herguin Benjamin Cuevas-Arellano, Juan Manuel Uribe-Ramos, Ramón Solano-Barajas, Yolitzy Cárdenas, Jesús Venegas-Ramírez, Eder Fernando Ríos-Bracamontes, Luis A García-Solórzano, Arlette A Camacho-delaCruz, Efrén Murillo-Zamora

“…Weekly case counts, obtained through the normative epidemiological surveillance system for vector-borne diseases, were used to calculate incidence rates per 100,000 population. Geographic Information Systems were employed to analyze spatial patterns, while Local Moran's I statistic and a k-nearest neighbors spatial weights matrix identified spatial clusters. …”
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Altered Translocation Pattern as Potential Glyphosate Resistance Mechanism in Blackgrass (<i>Alopecurus myosuroides</i>) Populations from Lower Saxony by Markus Radziewicz, Dirk M. Wolber, Thomas Pütz, Diana Hofmann

“…In a foregoing dose–response study, individual plants from four out of six tested populations survived full (1800 g a.i. ha⁻¹) or double (3600 g a.i. ha⁻¹) glyphosate dose rates permitted, suggesting the presence of tolerant biotypes with yet unknown resistance mechanisms. …”
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Diagnostic Modalities for Detecting Extrapulmonary Tuberculosis and Resistance Patterns of Rifampicin and Isoniazid at a Referral Hospital: A Retro Prospective Study by Ankur Kumar, Amresh Kumar Singh, Vivek Gaur, Ashwini Kumar Mishra, Anita Mehta, Raj Kishore Singh

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Study on the evolution patterns and predictive modeling of ambient air quality in oasis cities of arid regions: a case study of Urumqi by Bian Jing, Ren Xiaofeng

“…BackgroundThis study investigates the evolution patterns and future trends of ambient air quality in oasis cities within arid regions, with Urumqi as a representative case.MethodsUtilizing observational data from eight urban monitoring stations, we comprehensively analyze air quality variations and project future scenarios through the Air Quality Index (AQI), Spearman’s rank correlation coefficient, and Grey correlation modeling. …”
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Pattern and appropriateness of antibiotic therapy for acute respiratory tract infection among under-five children accessing care in a tertiary facility, Sokoto, Nigeria by Fatima Ishaq Abubakar, Hadiza Kubra Ahmed, Omotolani Olawunmi Akintunde, Idrees Abiodun Rufai

“…Introduction Acute respiratory tract infections (ARIs) are a major cause of antibiotic use among under-five (U5) children, often leading to inappropriate prescriptions that contribute to antimicrobial resistance, adverse drug reactions and higher healthcare costs.Objectives To assess the pattern and rate of antibiotic prescriptions and evaluate their appropriateness based on WHO and Paediatric Association of Nigeria guidelines for ARI treatment among U5 children at Usmanu Danfodiyo University Teaching Hospital, SokotoMethods A retrospective review of medical records (case folders and prescription sheets) was conducted for U5 children diagnosed with ARI over a 10-month period at the paediatric outpatient and inpatient units, Department of Paediatrics, UDUTH. …”
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Changes in psychiatric disorder incidence patterns during the COVID-19 pandemic in Korea: a study using the nationwide universal health insurance data by Changwoo Han, Juho Choi, Hoyeon Jang, Hwa-Young Lee, Tarik Benmarhnia, Juhwan Oh

“…First-ever diagnosis for specific psychiatric disorders for each Korean was identified (from January 2015 to February 2023) and monthly age-standardized incidence rates were calculated. An interrupted time-series analysis was used to estimate counterfactual disease incidence rates and observed and counterfactual rates were compared using difference-in-difference framework. …”
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High-speed threat detection in 5G SDN with particle swarm optimizer integrated GRU-driven generative adversarial network by R. Shameli, Sujatha Rajkumar

“…Moreover, the performance of this model is evaluated using the InSDN dataset and compared with existing DL model-based intrusion detection approaches and the results demonstrate a significantly higher accuracy rate of 98.4%, precision rate of 98%, recall rate of 98.5%, less detection time of 2.464 s, lesser Log loss rate of 1.0 and more metrics instilling confidence in the effectiveness of the proposed method.…”
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