Age and Tumor Stage Interplay in Intrahepatic Cholangiocarcinoma: Prognostic Factors, Mortality Trends, and Therapeutic Implications from a SEER-Based Analysis by Ayrton Bangolo, Vignesh K. Nagesh, Hadrian Hoang-Vu Tran, Brooke Sens, Daniel Elias, Behzad Amoozgar, Chase Tomasino, Izage Kianifar Aguilar, Charlene Mansour, Elizabeth Gagen, Lili Zhang, Sarvarinder Gill, Nisrene Jebara, Emma Madigan, Christin Candela, Dohaa Amin, Peter Giunta, Shubhangi Singh, Aman Siddiqui, Auda Auda, Paul Peej, Timophyll Y. H. Fong, Simcha Weissman, Printhia Matshi Lihau, John Bukasa-Kakamba

“…Furthermore, it examines the clinical features, survival rates, and prognostic indicators of ICC cases diagnosed between 2010 and 2017. …”
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Googling Patients by Emily Beer

“…Numerous wearable devices collect data on consumers’ heart rates, exercise patterns and sleep patterns. In-home smart devices can track when users are active and what they are doing in their homes. …”
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Energetics of Eddy–Mean Flow Interaction in the Kuroshio Current Region by Yang Wu, Dalei Qiao, Chengyan Liu, Liangjun Yan, Kechen Liu, Jiangchao Qian, Qing Qin, Jianfen Wei, Heyou Chang, Kai Zhou, Zhengdong Qi, Xiaorui Zhu, Jing Li, Yuzhou Zhang, Hongtao Guo

“…The cross-stream variation is found in the energy conversion pattern in the along-coast region, whereas a mixed positive–negative conversion pattern is observed in the off-coast region. …”
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Phylogeochemistry: exploring evolutionary constraints on belemnite rostrum element composition by A. Pohle, K. Stevens, R. Hoffmann, A. Immenhauser, A. Immenhauser

“…We used comparative Bayesian phylogenetic tools to reconstruct ancestral states and phenotypic evolutionary rates of these geochemical data based on trees inferred from morphological data. …”
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REGULARITIES OF FORMATION OF FLOW OF COOLANT BEHIND THE TVS-KVADRAT MIXING SPACING GRID OF THE PWR-TYPE REACTOR by S. M. Dmitriev, D. V. Doronkov, M. A. Legchanov, V. D. Sorokin, A. E. Khrobostov

“…During the studies of the local fluid dynamics of the coolant, the transverse flow rates were measured; also, the coolant flow rates were measured by cells of the TVS-Kvadrat experimental model. …”
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The impact of spatial placement on valence judgments of images: a comparative analysis between right-handed and left-handed individuals by Maisto Marta, Actis-Grosso Rossana

“…Thirty participants (15 right-handed, 15 left-handed) rated neutral images displayed in the center, right, or left visual field using a 9-point Likert scale. …”
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Paclitaxel resistance development is associated with biphasic changes in reactive oxygen species, mitochondrial membrane potential and autophagy with elevated energy production cap... by Satabdi Datta, Diptiman Choudhury, Amlan Das, Dipanwita Das Mukherjee, Nabanita Das, Sib Sankar Roy, Gopal Chakrabarti

“…Increase in extracellular acidification rates and oxygen consumption rates was found to be directly correlated with acquisition of resistance. …”
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Respiratory Support with Limited Tidal Volume and Peak Pressure in Patients with Acute Respiratory Distress Syndrome by A. V. Vlasenko, D. A. Ostapchenko, G. N. Meshcheryakov, P. Yu. Osipov

“…The paper presents the results of a study, which prove the advantages of artificial ventilation with a descending air flow on inspiration, tidal volume 6 ml/kg body weight; P peak < 30 cm H2O in showing its efficiency, by optimizing the parameters of the respiratory pattern, by improving gas exchange in the lung, by reducing the time of respiratory support, the length of stay in an intensive care unit, and mortality rates as compared with artificial square-wave air flow on inspiration, TV 12—15 ml/kg body weight; Ppeak tracheal >35 cm H2°.…”
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Risk of developing drug abuse in administration of a new hexaazaisowurtzitane derivative-based analgesic (experimental study) by S. G. Krylova, T. N. Pove’teva, K. A. Lopatina, Yu. V. Nesterova, E. P. Zueva, O. G. Afanas’eva, P. V. Kulpin, E. A. Kiseleva, N. I. Suslov, D. A. Kulagina, S. V. Sysolyatin, V. V. Zhdanov

“…Previous in vivo and in silico studies (docking, molecular modeling, molecular dynamics simulation) on the multi-target mechanism of thiowurtzine explain the absence of its morphine-like effect by the fact that the major targets of the analgesic are TRPA1 receptors and voltage-gated Ca 2+ channels. With a high degree of probability, the conclusions made herein predict no drug abuse development when thiowurtzine is used in the clinical setting. …”
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Advance, steadfast, retreat? Growth and establishment of white spruce seedlings at treelines in Alaska by Andreas Burger, Mario Trouillier, Martin Wilmking

“…In contrast, high seedling densities and growth rates at the cold treeline and cold forest indicate favorable conditions for seedling establishment and densification. …”
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Long-Term Multimodal Exercise Intervention for Patients with Frontotemporal Lobar Degeneration: Feasibility and Preliminary Outcomes by Miyuki Nemoto, Kiyotaka Nemoto, Hiroyuki Sasai, Shinji Higashi, Miho Ota, Tetsuaki Arai

“…Feasibility was measured using dropout and attendance rates. Cognitive, psychological, physical, and behavioral function tests were conducted before and after the intervention. …”
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Joint analysis of Borexino and SNO solar neutrino data and reconstruction of the survival probability by Francesco Vissani

“…Solar neutrino oscillations are supported by KamLAND’s antineutrino measurements, but certain solar neutrino data – the observed shape of the 8B flux and the difference between day and night counting rates measured in Super-K – do not fit well with the ensuing oscillation pattern. …”
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Improved chaotic fruit fly optimization with elman neural network based data-driven approach on product reviews classification by Mohammed Alghamdi, Najla I. Al-shathry, Yahia Said, Hasan Beyari, Shaymaa Sorour, Khalid Nazim Abdul Sattar, Fouad Shoie Alallah, Abdulrhman Alshareef

“…Customer satisfaction is effectively enhanced by performing a Sentiment Analysis (SA) of many customer ratings on E-commerce platforms. Yet, predicting the correct sentiment difference in customer feedback is challenging due to complicated logic, sequence length, and text pattern adjustments. …”
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Association between cumulative uric acid exposure and metabolic dysfunction-associated fatty liver disease by Yunpeng Li, Hong Ji, Fei Tian, Xinyu Ge, Liying Cao, Xiangming Ma

“…Corresponding cumulative incidence rates were 52.20%, 52.49%, 58.29%, and 60.50% respectively. …”
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Dorsal epidural disc migration—MRI characteristics and surgical microdiscectomy treatment: Case report and review of the literature by Antonios Michailidis, MD, Ioannis Tsifountoudis, MD, PhD, Dimitrios Kitridis, MD, FEBOT, MSc, PhDc, Konstantinos Tasoulis, MD, Kostas Charatsis, MD, Giannetopoulos Dimitrios, MD

“…This unusual migration pattern presents unique diagnostic challenges, as it can mimic other serious spinal pathologies such as epidural abscesses, hematomas, and synovial cysts. …”
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ANALYSIS OF THE EFFICIENCY OF CRYOGENIC TREATMENT FOR TONGUE CANCER by T. D. Tabolinovskaya, I. N. Pustynsky

“…The cryogenic treatment results that have no analogues in Russian and foreign practice were analyzed in 121 patients with tongue cancer. The data on survival rates were used to objectively evaluate the efficiency of tongue cancer cryodestruction in accordance with the extent and pattern of a tumor process. …”
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TREATMENT OF IgG4-RELATED DISEASE by E. V. Sokol, V. I. Vasilyev

“…IgG4-related disease (IgG4-RD) is a fibroinflammatory condition characterized by the occurrence of tumor-like foci in different organs with a unique histological pattern (moirо-like fibrosis, obvious lymphoplasmacytic infiltration with large numbers of IgG4+ plasma cells, and obliterating phlebitis) and elevated serum IgG4 levels in the majority of patients. …”
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EARTH SURFACE DEFORMATION OF THE SAKHALIN ISLAND FROM GPS DATA by A. S. Prytkov, N. F. Vasilenko

“…Recently, the seismic activity has been increased in the areas characterized by intensive surface deformation, while the areas of low deformation rates correlate with the zones of weak and sparse seismicity.…”
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Dynamics of mental state and prolactin levels in patients with chronic schizophrenia during aripiprazole therapy by L. N. Gorobets, I. V. Dorovskikh, A. V. Litvinov, V. S. Bulanov, S. K. Gamdullaev, T. A. Pavlova

“…The effectiveness of therapy does not depend on the background values of the hormone: at high rates, prolactin levels decrease, and at low rates, they increase. …”
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Post-marketing safety concerns with dolutegravir: a pharmacovigilance study based on the FDA adverse event reporting system database by Juan Su, Long He, Menglei Wang

“…Notably, subgroup analyses revealed that progressive multifocal leukoencephalopathy (n = 9) in males, progressive multifocal leukoencephalopathy (n = 6) and deafness neurosensory (n = 3) in the 18–45 age group, and hepatic necrosis (n = 4) in the 46–65 age group were rated as high clinical priority. The overall onset time for all AEs exhibited an early failure pattern, with a median onset time of 74 days (IQR 19–310.5), whereas the median onset time for designated medical events (DMEs) was 59 days (IQR 12–186).ConclusionThe long-term safety of DTG requires reassessing its risk-benefit ratio. …”
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