Multiple sclerosis mortality trends in Spain from 1981 to 2020 by L. Cayuela, A. de Albóniga-Chindurza, S. Gómez Enjuto, J. Lapeña-Motilva, S. Sainz de la Maza, A. González García, A. Cayuela

“…Age-standardised mortality rates (ASMR) and trend analysis were performed using joinpoint regression software. …”
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SERPINA3 predicts long-term neurological outcomes and mortality in patients with intracerebral hemorrhage by Pei Zheng, Zhihui Qi, Bin Gao, Yang Yao, Jingshan Chen, Hengri Cong, Yue Huang, Fu-Dong Shi

“…Abstract Intracerebral hemorrhage (ICH) is a severe stroke subtype with high mortality and disability rates, and long-term outcomes among survivors remain unpredictable due to the lack of reliable biomarkers. …”
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Review of Epidemiological Situation on Rickettsioses in the Russian Federation in 2022 as Compared with 2013–2021, Forecast for 2023 by N. A. Pen’evskaya, N. V. Rudakov, S. N. Shpynov, A. I. Blokh, D. V. Trankvilevsky, D. A. Savel’ev, S. V. Shtrek, A. V. Sannikov

“…The aim of the review was to characterize the epidemiological situation on tick-borne rickettsioses (TR) in the Russian Federation in 2022 in comparison with the pandemic years of 2020–2021 and the pre-pandemic period of 2013–2019, to give the forecast for 2023. During 2013–2022, a pattern was observed in the incidence of rickettsiosis of the tick-borne spotted fever group (with the exception of Astrakhan spotted fever – ASF), that is also characteristic of most other natural focal infections (NFIs): a sharp decrease in registered incidence rates in 2020–2021 with the subsequent increase in 2022 almost up to pre-pandemic levels or even exceedance in some regions. …”
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Psychiatric comorbidities and smoking behavior in chronic obstructive pulmonary disease: A case–control study from a north Indian tertiary Center by Rohit Pathak, Abhishek Pathak, Manish Singh

“…Results: Cases exhibited significantly higher rates of smoking, with regular smokers constituting 51.1% compared to 14.0% of controls (P=0.0001). …”
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Content-Based Brain Magnetic Resonance Image Retrieval and Classification With the Proposed Deep Learning and Tissue-Based System by Bedriye Dogan, Hursit Burak Mutlu, Muhammed Yildirim, Sercan Yalcin, Serpil Aslan, Niranjana Sampathila, Ozal Yildirim, Edward J. Ciaccio, Ru-San Tan, U. Rajendra Acharya

“…Notably, existing machine architectures already published in the literature have struggled to achieve comparable success rates in discerning such closely related yet distinct disease groups. …”
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Clinical features of patients with dysthymia in a large cohort of Han Chinese women with recurrent major depression. by Wenqing Wu, Zhoubing Wang, Yan Wei, Guanghua Zhang, Shenxun Shi, Jingfang Gao, Youhui Li, Ming Tao, Kerang Zhang, Xumei Wang, Chengge Gao, Lijun Yang, Kan Li, Jianguo Shi, Gang Wang, Lanfen Liu, Jinbei Zhang, Bo Du, Guoqing Jiang, Jianhua Shen, Ying Liu, Wei Liang, Jing Sun, Jian Hu, Tiebang Liu, Xueyi Wang, Guodong Miao, Huaqing Meng, Yi Li, Chunmei Hu, Yi Li, Guoping Huang, Gongying Li, Baowei Ha, Hong Deng, Qiyi Mei, Hui Zhong, Shugui Gao, Hong Sang, Yutang Zhang, Xiang Fang, Fengyu Yu, Donglin Yang, Tieqiao Liu, Yunchun Chen, Xiaohong Hong, Wenyuan Wu, Guibing Chen, Min Cai, Yan Song, Jiyang Pan, Jicheng Dong, Runde Pan, Wei Zhang, Zhenming Shen, Zhengrong Liu, Danhua Gu, Xiaoping Wang, Xiaojuan Liu, Qiwen Zhang, Yihan Li, Yiping Chen, Kenneth S Kendler, Jonathan Flint, Zhen Zhang

“…<h4>Conclusions</h4>There are increased rates of stressful life events in MDD with dysthymia, but the impact of life events on susceptibility to dysthymia with MDD differs from that seen for MDD alone. …”
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A Long-Term Overview of Elasmobranch Fisheries in an Oceanic Archipelago: A Case Study of the Madeira Archipelago by Mafalda Freitas, Filipa Pinho-Duarte, Madalena Gaspar, Pedro Ideia, João Delgado, Sara C. Cerqueira, Ricardo Sousa

“…The most representative period occurred from 2003 to 2013, corresponding to 75.21% of the total elasmobranch landings. A general pattern of supply and demand was evident, with mean price values typically showing an inverse trend to landed tonnage. …”
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Toxicokinetics, tissue distribution, and toxic potency of PFOS alternative OBS in adult zebrafish (Danio rerio) based on flow-through exposure system by Yilong Zou, Yu Zhou, Xianglian Wang, Guiqing Gao, Gang Chen, Zhanmeng Liu, Mi Deng, Xueping Huang, Yongming Wu

“…Our findings indicate that OBS accumulated rapidly in zebrafish, with log kinetic bioconcentration factor (logBCFk) values ranging from 2.48 to 2.70 and slow elimination rates (ke = 0.0490–0.0643 d−1). The blood, liver, and muscle were responsible for over 50 % of the total body burden of OBS, with tissue concentrations decreasing in the following order: blood > liver > intestine > gills > gonad > brain > muscle, suggesting a tissue-specific accumulation pattern. …”
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The large and central Caligo martia eyespot may reduce fatal attacks by birds: a case study supports the deflection hypothesis in nature by Iserhard, Cristiano Agra, Malta, Shimene, Penz, Carla, Fraga, Brenda Barbon, Costa, Camila Abel, Schwantz, Taiane, Bordin, Kauane Maiara

“…Eyespots did not appear to reduce attack rates, suggesting that local bird species were not intimidated. …”
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Reward-related neural activation during social media exposure in young women with non-suicidal self-injury: evidence for a continuum of severity in the reward network by Stella Nicolaou, Anna Julià, Daniela Otero, Carlos Schmidt, Juan Carlos Pascual, Joaquim Soler, Josep Marco-Pallarés, Daniel Vega

“…Clinical participants rated positive comments as less pleasant and negative comments as more unpleasant than controls. …”
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IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling. by Helen M Lazear, Alissa Lancaster, Courtney Wilkins, Mehul S Suthar, Albert Huang, Sarah C Vick, Lisa Clepper, Larissa Thackray, Margaret M Brassil, Herbert W Virgin, Janko Nikolich-Zugich, Ashlee V Moses, Michael Gale, Klaus Früh, Michael S Diamond

“…Whereas the gene induction pattern in DKO mDC was similar to WT cells, remarkably, almost no ISG induction was detected in TKO or Mavs(-/-) mDC. …”
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In Silico Designed Multi-Epitope Vaccine Based on the Conserved Fragments in Viral Proteins for Broad-Spectrum Protection Against Porcine Reproductive and Respiratory Syndrome Viru... by Shaukat Ullah, Hikmat Ullah, Kainat Fatima, Tan Lei

“…This virus includes two major genotypes, PRRSV1 and PRRSV2, both characterized by high mutation rates and genetic variability, complicating the development of a universally effective vaccine and disease control. …”
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Cumulative risk of revision after primary total hip arthroplasty in registries internationally: systematic review and meta-analysis of selected hip stems and cups by Christophe Combescure, James A Smith, Christophe Barea, Lotje A Hoogervorst, Rob Nelissen, Perla J Marang-van de Mheen, Anne Lübbeke, the Arthroplasty registry group

“…Purpose: The objective was to investigate the consistency in cumulative revision rates (CRRs) for a selection of total hip arthroplasty cups and stems across national/regional hip arthroplasty registries worldwide. …”
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Erosion of estimated genomic breeding values with generations is due to long distance associations between markers and QTL by Didier Boichard, Sébastien Fritz, Pascal Croiseau, Vincent Ducrocq, Thierry Tribout, Beatriz C. D. Cuyabano

“…In Method 2 all the QTL contributions to SNP effects are regressed based on SNP-QTL recombination rates and summed to predict the GEBV at the next generation. …”
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Fabrication and Characterization of Si Substrate-Free InGaN Light-Emitting Diodes and Their Application in Visible Light Communications by Chia-Lung Tsai, Ying-Chang Li, Yi-Chen Lu, Sheng-Hsiung Chang

“…A direct line-of-sight optical link using the proposed thin-film LEDs achieved data transmission rates of up to 100 Mb&#x002F;s over a distance of 100 cm, indicating that the proposed LEDs have potential for use as optical transmitters in indoor visible light communications.…”
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Succession of Lichens in Front of Retreating Glaciers in Sweden and Norway by Josef P. Halda, Jan Košnar, Alena Lukešová

“…Lichen succession follows the expected pattern, primarily shaped by terrain microtopography, climate, and substrate type. …”
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Barriers and facilitators for the practice of occupational therapy in mental health: findings from a global practitioner survey of the World Federation of Occupational Therapists by Tiago S. Jesus, Pedro C. Monteiro, Ritchard Ledgerd, Claudia von Zweck, World Federation of Occupational Therapists

“…Of the nine surveyed factors, six (66%) were rated more often as barriers for practice, including “waiting times”, “services funding”, “intervention costs”, and “therapists availability”. …”
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Modulatory role of radioprotective 105 in mitigating oxidative stress and ferroptosis via the HO-1/SLC7A11/GPX4 axis in sepsis-mediated renal injury by Hong Duo, Yanwei Yang, Jun Luo, Yumeng Cao, Qian Liu, Jiarui Zhang, Siqi Du, Jian You, Guqing Zhang, Qifa Ye, Huaqin Pan

“…Abstract Sepsis-associated acute kidney injury (SA-AKI) is a critical condition characterized by high morbidity and mortality rates, particularly in intensive care settings. This study focuses on RP105, a pattern recognition receptor, exploring its role in moderating the mechanisms of oxidative stress and ferroptosis during SA-AKI, offering insights into its potential as a therapeutic target. …”
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Real-World Evidence of Safety and Efficacy of Carboplatin plus Nanoparticle Albumin-Bound Paclitaxel in Patients with Advanced Non-Small-Cell Lung Cancer and Preexisting Interstiti... by Tomoyuki Araya, Toshiyuki Kita, Tsukasa Ueda, Nanao Terada, Tamami Sakai, Kenta Yamamura, Koji Kurokawa, Yuka Uchida, Takashi Sone, Hideharu Kimura, Kazuo Kasahara

“…The overall response and disease control rates were 77.8% (95% CI, 40.0–97.2) and 88.9% (95% CI, 51.8–97.2), respectively. …”
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Comprehensive analysis of Enterococcus spp. from two European healthy infant cohorts shows stable genomic traits including antimicrobial resistance (AMR) by Muhammad Hassan Saeed, Magdalena Kujawska, Kristiana Ellen, Antia Acuna-Gonzalez, Manuel Bernabeu Lorenzo, Maria Carmen Collado, Monique Mommers, Niels van Best, Lindsay J. Hall, Klaus Neuhaus

“…We also selected ten E. faecalis isolates with varying virulence gene repertoires for phenotypic virulence testing in Caenorhabditis elegans and found them killing at various rates, however no clear pattern emerged in correlation with any specific genetic determinant. …”
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