Evaluating the potential of phenotypic age to enhance cardiovascular risk prediction over chronological age in the UK Biobank by Kristine J. S. Kwan, Shi-Shuai Xie, Hai-Lei Li, Xue-Guang Lin, Yi-Jie Lu, Bo Chen, Kai-Xin Ge, Shu-Ya Tang, Hui Zhang, Shuai Jiang, Jing-Dong Tang

“…Incident CVD occurred at a higher rate in the positive PhenoAgeAccel group (44.8% vs. 33.1%) at a comparatively shorter period (11.2 years vs. 12.4 years). …”
Get full text

Insights on the effect of mega-carcass abundance on the population dynamics of a facultative scavenger predator and its prey by Sidous, Mellina, Cubaynes, Sarah, Gimenez, Olivier, Drouet-Hoguet, Nolwenn, Dray, Stéphane, Bollache, Loïc, Madhlamoto, Daphine, Ngwenya, Nobesuthu Adelaide, Fritz, Hervé, Valeix, Marion

“…Models that allow hyaena and their prey populations’ growth rate to vary depending on these four periods contributed significantly to explain variations in their density, which is consistent with an effect of management measures on the population dynamics of hyaena and its prey.  …”
Get full text

Extranodal diffuse large B‐cell lymphoma: Clinical and molecular insights with survival outcomes from the multicenter EXPECT study by Si‐Yuan Chen, Peng‐Peng Xu, Ru Feng, Guo‐Hui Cui, Li Wang, Shu Cheng, Rong‐Ji Mu, Hui‐Lai Zhang, Xiao‐Lei Wei, Yong‐Ping Song, Kai‐Yang Ding, Li‐Hua Dong, Zun‐Min Zhu, Shen‐Miao Yang, Xin Wang, Ting‐Bo Liu, Jian‐Da Hu, Xiao‐Yun Zheng, Ou Bai, Jing‐Yan Xu, Liang Huang, Wei Sang, Ke‐Qian Shi, Fan Zhou, Fei Li, Ai‐Bin Liang, Hui Zhou, Si‐Guo Hao, Hong‐Hui Huang, Bin Xu, Wen‐Bin Qian, Cai‐Xia Li, Zhi‐Ming Li, Chong‐Yang Wu, Xiao‐Bo Wang, Wen‐Yu Shi, Shu‐Ye Wang, Yu‐Yang Tian, Xi Zhang, Ke‐Shu Zhou, Li‐Juan Cui, Hui Liu, Huo Tan, Qing Leng, Dong‐Lu Zhao, Ting Niu, Wei‐Li Zhao

“…Gene panel sequencing was performed on 1,050 patients to discern molecular patterns according to ENI. Results The 2‐year overall survival (OS) rate was 76.2% [95% confidence interval (CI), 74.0%‐78.2%], and the 5‐year OS rate was 67.9% (95% CI, 65.2%‐70.4%). …”
Get full text

Therapeutic Effects of Forest Bathing on Human Health: A Systematic Review by Adrianna Samoraj, Jakub Zajączkowski, Paulina Krzeszowska, Kacper Stępniak, Karolina Marrodán-Wojtczak, Jan Wilk, Jakub Jarmołowicz, Aleksandra Kujawa, Karolina Krochmal, Radosław Kuźma

“…Specifically, a reduction in heart rate, as well as systolic and diastolic blood pressure, was observed in individuals who participated in forest excursions.  …”
Get full text

Clinical Presentation, Pathological Spectrum, and Outcomes of Alcoholic Cirrhosis-Related Immunoglobulin A Nephropathy by Charles Ronsin, Pierre Braud, Christine Kandel-Aznar, Amaury Dujardin, Clémence Petit, David Larmet, Claire Garandeau, Clément Deltombe, Alice Le Clech, Claire Leman, Gilles Blancho, Juliet Schurder, Grégoire Couvrat-Desvergnes, Simon Ville

“…The cumulative mortality rate in cirrhosis-IgAN was 26% and 46% at 1-year and 3-years, respectively. …”
Get full text

Influence of the extent of cervical lymph node dissection and lymph nodes metastases on prognosis in a cohort of dogs with oral malignant melanoma treated by surgical resection and... by Davide Giacobino, Matteo Olimpo, Erica Ilaria Ferraris, Greta Martinelli, Lorella Maniscalco, Mariateresa Camerino, Federica Riccardo, Federica Cavallo, Lidia Tarone, Marzia Cino, Alfredo Dentini, Selina Iussich, Elena Lardone, Luca Manassero, Raffaella De Maria, Paolo Buracco, Emanuela Morello

“…The overall LN metastatic rate was 31%; metastasis was found mostly in the mandibular lymph center (83%). …”
Get full text

Diagnostic work-up of anemia and associated health outcomes in people with heart failure by Guobin Su, Ruowei Xiao, Dongze Ji, Kaiyu He, Anna Hallert, Gianluigi Savarese, Lars H. Lund, Yang Xu, Juan Jesus Carrero

“…Time-varying Cox regression explored associations between developing anemia and rate of major adverse cardiovascular events (MACE), HF hospitalization, cancer, and death. …”
Get full text

Sociodemographic and regional differences in neonatal and infant mortality in Switzerland in 2011–2018: the Swiss National Cohort by Veronika W. Skrivankova, Leonie D. Schreck, Claudia Berlin, Radoslaw Panczak, Kaspar Staub, Marcel Zwahlen, Sven M. Schulzke, Matthias Egger, Claudia E. Kuehni

“… BACKGROUND AND AIMS: Despite a well-funded healthcare system with universal insurance coverage, Switzerland has one of the highest neonatal and infant mortality rates among high-income countries. Identifying avoidable risk factors targeted by evidence-based policies is a public health priority. …”
Get full text

Miotonia congênita: relato de sete pacientes Congenital myotonia: report of seven patients by Helga C. A. Azevedo, Lúcia I. Z. Mendonça, Paulo N. B. Salum, Mary S. Carvalho, Sueli K. Nagahashi-Marie, Alzira A. Siqueira-Carvalho, Maria A. Cerqueira, Umbertina C. Reed, José A. Levy

“…<br>Myotonia is the phenomenon of decrease of muscular relaxation rate, after either a contraction or a mechanical or electrical stimulus. …”
Get full text

Assessment of the Impacts of Different Carbon Sources and Sinks on Atmospheric CO₂ Concentrations Based on GEOS-Chem by Ge Qu, Jia Zhou, Yusheng Shi, Yongliang Yang, Mengqian Su, Wen Wu, Zhitao Zhou

“…The results show that global CO₂ concentration exhibits a spatial pattern with higher concentrations in the Northern Hemisphere and land areas, with East Asia, Southeast Asia, and eastern North America being high-concentration regions. …”
Get full text

Optimizing fertilizer application and straw return to fields to minimize nitrogen and phosphorus runoff losses in double-rice cropping systems by Ying Zhang, Jian Zhu, Changjun Li, Hua Peng, Ji Liu, Yue Luo, Min Song, Yanjiao Dai, Kai Deng, Xionghui Ji

“…Unknown of long-term patterns of losses and mechanisms driving runoff N and P in double-rice cropping systems limited the development of effective mitigation strategies. …”
Get full text

Clinical Features of Liver Injury Induced by Immune Checkpoint Inhibitors in Japanese Patients by Koji Imoto, Motoyuki Kohjima, Tomonobu Hioki, Tomoyuki Kurashige, Miho Kurokawa, Shigeki Tashiro, Hideo Suzuki, Akifumi Kuwano, Masatake Tanaka, Seiji Okada, Masaki Kato, Yoshihiro Ogawa

“…Immune checkpoint inhibitors (ICIs) have improved the survival rate of patients carrying various malignant neoplasms. …”
Get full text

Association of cancer and outcomes of patients hospitalized for COVID-19 between 2020 and 2023 [version 2; peer review: 1 approved, 2 approved with reservations, 1 not approved] by Robert F Terry, Rugiatu Z Kamara, Robert J Samuels, Donald S Grant, Sulaiman Lakoh, Mustapha Kabba, Innocent Nuwagira, Yusuf Sheku Tejan, Sia Morenike Tengbe, Ibrahim Franklyn Kamara, Shermarke Hassan, Abdulai Tejan Jalloh, Divya Nair, Laura Merson

“…Conclusions This study's findings underscore the heightened vulnerability of hospitalized COVID-19 patients with cancer, revealing a higher mortality rate, longer hospital stays, and an unstructured pattern of care that reflects the complexity of managing severely ill patients during a public health crisis like the COVID-19 pandemic.…”
Get full text

Eradication of Helicobacter pylori for prevention of aspirin-associated peptic ulcer bleeding in adults over 65 years: the HEAT RCT by CJ Hawkey, Anthony J Avery, Carol AC Coupland, Colin J Crooks, Jennifer S Dumbleton, FD Richard Hobbs, Denise Kendrick, Michael Moore, Clive Morris, Gregory Rubin, Murray Smith, Diane Stevenson

“…Limitations and future work Studying subjects already established on aspirin probably contributed to the low event rate. A future study should investigate subjects starting on aspirin when the event rate is higher. …”
Get full text

Habit-learning and decision-making circuits are susceptible to glycemic variability in type 2 diabetes: a longitudinal study by Carolina Moreno, Carolina Moreno, Carolina Moreno, Otília C. d’Almeida, Otília C. d’Almeida, Joana Crisóstomo, Nádia Canário, Leonor Gomes, Leonor Gomes, Leonor Gomes, Miguel Castelo-Branco, Miguel Castelo-Branco

“…Linear regression analysis showed that, for each increase of 1 mmol/L in MAGE value, the SPC of the temporal lobe decreases on average by 1.2% (higher atrophy rate).ConclusionThe relationship between longitudinal GM atrophy and GV has a regionally specific pattern, suggesting localized brain susceptibility to intra-daily glucose fluctuations. …”
Get full text

Short light/dark cycles favour photosynthetic efficiency and growth in grapevines by Mariana Gómez Tournier, Laurent Torregrosa, Jana Kändler, Angélique Christophe, Romain Boulord, Anna Medici, Anne Pellegrino

“…T3/3 in both genotypes maintained stable net photosynthetic rates (An) and high photosystem II efficiency (φPSII) during the light cycle, avoiding the 62 % drop observed under T12/12 after 3 h of exposure. …”
Get full text

Viral characterization of the reassortants between canine influenza H3N2 and human pandemic (2009) H1N1 and avian H9N2 viruses in canine ex vivo tracheal explants by Tonia T. Kam, Christine H. T. Bui, Hin-Wo Yeung, Peter C. H. Wong, Alex W. H. Chin, John M. Nicholls, Malik Peiris, Kenrie P. Y. Hui, Leo L. M. Poon, Michael C. W. Chan

“…Results Co-passaging H3N2-CIV with human/avian influenza A viruses in canine tracheal explants resulted in a high rate of reassortment. Plaque-purified reassortants were all viable and able to propagate in mammalian alveolar epithelial cells. …”
Get full text

Comparing survival outcomes of anti-fibrotic therapy for idiopathic pulmonary fibrosis with and without emphysema: a multi-center real-world study from Taiwan by Yu-Hung Fang, Yi-An Hsieh, Yen-Fu Chen, Yu-Chi Chiu, Yu-Ching Lin, Kuo-Tung Huang, Yung-Chia Huang, Yu-Feng Wei, Chien-Wen Huang, Pin-Kuei Fu, Taiwan Multi-Centre Interstitial Lung Disease Research Consortium

“…During a median follow-up of 3.7 years, the overall survival rates were comparable (IPF only: 45.6%; IPF with emphysema: 48.4%). …”
Get full text

IMPACT OF THE INFLAMMATORY AND ISCHEMIC HEART DISEASE MARKERS INTO THE OVERALL CARDIOVASCULAR MORTALITY IN SENILE CITIZENS OF A LARGE CITY (THE DATA FROM SAHR TRIAL) by S. A. Shalnova, S. E. Evstifeeva, A. D. Deev, V. A. Metelskaya, A. V. Kapustina, G. A. Muromtseva, Yu. A. Balanova, E. M. Tuaeva, A. E. Imajeva, N. V. Kiseleva, M. A. Shkolnikova

“…For the assessment of current subclinical inflammation we used high-sensititvity C-reactive protein (hsCRP), interleucine 6 (IL-6), fibrinogen (FG), leucocytes, erythrocyte sedimentation rate (ESR). For CHD screening, we used standard ROse questionnaire and ECG pattern by Minnesota coding. …”
Get full text

A clinico-epidemiological study, assessing possible predictors of mortality and health-related quality of life for people living with visceral leishmaniasis – human immune virus (V... by Niyamat Ali Siddiqui, Dhruv Kumar Pandey, Ashish Kumar Singh, Sanjay Kumar Sinha, Mohd. Zahid Ansari, Rishikesh Kumar, Biplab Pal, Vidya Nand Rabi Das, Rajatashuvra Adhikary, Saurabh Jain, Krishna Pandey

“…These patients have a poor VL therapeutic success rate, more drug-related toxicity, and relapses resulting in high mortality. …”
Get full text