An epigenome-wide association study in the case-control study to explore early development identifies differential DNA methylation near ZFP57 as associated with autistic traits by Ellen M. Howerton, Valerie Morrill, Rose Schrott, Jason Daniels, Ashley Y. Song, Kelly Benke, Heather Volk, Homayoon Farzadegan, Aimee Anido Alexander, Amanda L. Tapia, Gabriel S. Dichter, Lisa A. Croen, Lisa Wiggins, Genevieve Wojcik, M. Daniele Fallin, Christine Ladd-Acosta

“…We sought to identify DNA methylation patterns in child blood associated with Social Responsiveness Scale score, Second Edition (SRS). …”
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Dynamics of cerebral blood flow following sertraline treatment in adolescent depression by Wenyu Ren, Wenyu Ren, Xiao Liu, Zhiwei Zhang, Xiaoqin Zhang, Wei Wu, Xingyu Wang, Zhihui Yu, Chuan Liu, Renqiang Yu

“…Furthermore, Pearson correlation analysis was employed to examine associations between changes in regional CBF and clinical improvement, as measured by changes in the 17-item Hamilton Depression Rating Scale (HAMD-17) scores.ResultsAt baseline, adolescents with depression exhibited increased CBF in the posterior cuneus and decreased CBF in the middle temporal gyrus (MTG), right middle orbitofrontal gyrus, and the left middle frontal gyrus (MFG), compared to healthy controls. …”
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Real-Time, Risk-Based Clinical Trial Quality Management in China: Development of a Digital Monitoring Platform by Min Jiang, Shuhua Zhao, Yun Mei, Zhiying Fu, Yannan Yuan, Jie Ai, Yuan Sheng, Ying Gong, Jingjing Chen

“…Quality findings from the early-stage, interim-stage, and conclusion-stage QC rounds of clinical trials were rated by using 3 severity grades (minor, major, or critical) and classified into 5 categories (with 4 taxonomy levels under each category). …”
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Loss of Reduction in Pediatric Distal Radius Fractures: Risk Factors From a Prospective Multicenter Registry by Apurva S. Shah, MD, MBA, Zoe E. Belardo, BA, Mark L. Miller, MD, Michael C. Willey, MD, Susan T. Mahan, MD, MPH, Divya Talwar, PhD, MPH, Donald S. Bae, MD

“…On multivariate analysis, metaphyseal bicortical fracture pattern (OR = 2.3), prereduction translation of ≥51% (OR = 2.3), and nonanatomic closed reductions (OR = 1.9) independently increased the odds of LOR. …”
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Criminal legal penalties, substance use, and overdose: a concept mapping study examining Colorado’s criminal legal penalties by Katherine LeMasters, Samantha K. Nall, Cole Jurecka, Betsy Craft, Paul J. Christine, Ryan Goodman, Jessie Henderson, Robert Haywood-James, Angela Williams, Grace Wittner, Joshua A. Barocas

“…Participants — recruited from community-based organizations — identified, rated, sorted, and categorized factors affecting criminal legal involvement, substance use, and/or overdose in their community. …”
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Analysis of influencing factors for primary membranous nephropathy complicated with atherosclerotic cardiovascular disease and establishment of a nomogram prediction model by Mirixiatijiang· Maimaiti, Zhu Guo-qiang, Su Ming-jie, Halinuer· Shadekejiang, Zhang Xue-qin, Lu Chen

“…They also had significantly higher systolic blood pressure ［130（120， 142） mmHg（1 mmHg=0.133 kPa） <italic>vs</italic> 122.0（113.5， 135.5） mmHg］， higher diastolic blood pressure ［80 （75， 90） mmHg <italic>vs</italic> 80（70， 85.5） mmHg］， higher prevalence of hypertension［142（64.8%） <italic>vs</italic> 67 （32.7%）］， and higher proportion of manual workers［60（27.4%） <italic>vs</italic> 28（13.7%）］ Additionally， lymphocyte count （LYM）， platelet count （PLT）， blood sodium concentration （Na）， blood urea nitrogen （BUN）， blood creatinine （Cr）， estimated glomerular filtration rate （eGFR）， 24-hour quantitative urine protein， glutamic transaminase， urinary occult blood， number of urinary hyaline and pathological tubular patterns， C-reactive protein （CRP）， complement C4， plasma fibrinogen， D-dimer， and centrocyte-lymphocyte ratio were all significantly different between the two groups （<italic>P</italic>&lt;0.05）. …”
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A data-driven approach to forest health assessment through multivariate analysis and machine learning techniques by Raja Waqar Ahmed Khan, Hamayun Shaheen, Muhammad Ejaz Ul Islam Dar, Tariq Habib, Muhammad Manzoor, Syed Waseem Gillani, Abeer Al-Andal, John Oluwafemi Ayoola, Muhammad Waheed

“…RF-based feature importance analysis showed tree DBH, height, regeneration rate, soil erosion, and tree density as key ecological drivers of forest health. …”
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Citronella oil-loaded electro-spun single and core-shell nano fibers as sustained repellent systems against Aedes aegypti by Samali Udara Liyanaarachchi, Sanjeewa K. Rodrigo, Nilwala Kottegoda, Veranja Karunaratne, Menaka Hapugoda, Tharaka Ranathunge, Lahiru Udayanga, Dushmantha Adikari

“…It was found that maintaining the outer:inner flow rate ratio at 5:2 in coaxial process is imperative to produce good fibers. …”
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Functioning in patients with major depression treated with duloxetine or a selective serotonin reuptake inhibitor in East Asia by Novick D, Montgomery W, Haro JM, Moneta MV, Zhu G, Yue L, Hong J, Duenas H, Brugnoli R

“…Depression severity was assessed using the 16-item Quick Inventory of Depressive Symptomatology-Self Report. PPS were rated using the modified Somatic Symptom Inventory. …”
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Effects of Hole Irrigation Device Parameters on Soil Water Characteristics Under Different Biogas Slurry Ratios by Peng Xiang, Jian Zheng, Yan Wang, You Wu

“…The lateral and vertical wetting front migration distances exhibited a well-defined power function relationship with the soil’s stable infiltration rate and infiltration time (<i>R</i>² ≥ 0.977). …”
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Assessment of predictors and mitigation strategy for therapeutic inertia in the management of hypertension: a quality improvement project by Ananyan Sampath, Shreya Deshpande, Rashmi Verma, Rajnish Joshi

“…When patient adherence was disregarded, TI increased to 49.7%. The total error rate in BP management ranged from 53.29% to 61.5%. …”
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Epigenetic dysregulation-induced metabolic reprogramming fuels tumor progression in bladder cancer by Jian Zhang, Xiaosong Fan, Xu Xu, Yichao Han, Weixing Yu, Bicheng Yang, Yanling Chen, Shaolin Zhang

“…BackgroundBladder cancer remains a significant global health challenge with a high mortality rate despite advancements in treatment modalities. …”
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Assessment of Water Resources Carrying Capacity and Analysis of Its Coupling Coordination in the Yangtze River Economic Belt by XIONG Ying, JIANG Yi-xin, CHEN Si-xuan

“…Analysis of influencing factors identified the proportion of tertiary industry, urbanization rate, and per capita daily domestic water consumption as the three factors most strongly correlated with water resources carrying capacity. …”
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Assessment of heavy metal pollution sources and environmental capacity of typical farmland soils in northwestern Zhejiang based on the geological background of black rock series by Mei-hua Wang

“…Principal component analysis extracted four principal components with a cumulative contribution rate of 78.92%, and the spatial distribution differences were obvious. …”
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Eco-friendly QbD-optimized chromatographic method for simultaneous analysis of metronidazole and nicotinamide with applications in permeation, stability, and sustainability evaluat... by Kanaka Parvathi Kannaiah, Mohamed A. M. Ali, Hemanth Kumar Chanduluru, Anis Ahmad Chaudhary, Mahmoud El-Maghrabey, Reem H. Obaydo, Galal Magdy, Mohamed A. El Hamd

“…The in vitro permeation curve, constructed by plotting mass flux in. μg/cm2.hour against mid-time in hours, showed similar permeation patterns for both drugs over time. The permeation coefficient (Kp) values for MTZ and NCT were 0.016 and 0.012 × cm−2. hour−1, respectively. …”
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Longitudinal evaluation of common and unique brain-networks in variants of primary progressive aphasia by Rajan Kashyap, Rose Dawn Bharath, Changsong Zhou, Kyrana Tsapkini, John E. Desmond, SH Annabel Chen, Kaviraja Udupa, PT Sivakumar, Sagarika Bhattacharjee

“…To validate the rsfMRI networks and the longitudinal changes, we evaluated the grey matter (GM) volume, GM atrophy and the rate-of-atrophy of the brain areas. To corroborate the findings, we applied persistent homology on the structural networks derived from diffusion tensor images. …”
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Mixture of prompts learning for vision-language models by Yu Du, Yu Du, Yu Du, Yu Du, Yu Du, Tong Niu, Tong Niu, Tong Niu, Tong Niu, Tong Niu, Rong Zhao, Rong Zhao, Rong Zhao, Rong Zhao, Rong Zhao

“…Additionally, we introduce a novel gating mechanism to ensure the router selects prompts based on their similarity to hard prompt templates, which both retains knowledge from hard prompts and improves selection accuracy. …”
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Research on process optimization and trajectory planning of EA4T axle robot grinding by Feng ZHANG, Zhongli FENG, Feng XU, Deming ZHANG, Xiangrui ZENG, Jianwei MA, Shilei ZHANG

“…The grinding force, feed rate and spindle speed corresponding to the optimal grinding process parameters are entered into the control system. …”
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A mobile app to improve adherence to colorectal cancer screening and post polypectomy surveillance guidelines by María A. Casas, Francisco Schlottmann, Leandro Steinberg, Xavier Bessa, Anna Serradesanferm, Angels Pozo, Sonia Torres, Antoni Castells, Francesc Balaguer, Jaume Grau, Lisandro Pereyra, María Pellisé

“…Users’ characteristics, consultation types, and patient data were analyzed to assess app’s implementation, usage patterns, and impact on CRC screening and surveillance outcomes. …”
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Ultrafast complex-valued 4D fMRI reveals sleep-induced brain respiratory pulsation changes in both magnitude and phase signals by Saara Sofia Syväoja, Lauri Raitamaa, Heta Helakari, Jussi Kantola, Matti Järvelä, Janne Kananen, Ville Isokoski, Vesa Korhonen, Tommi Väyrynen, Timo Tuovinen, Jürgen Hennig, Vesa Kiviniemi

“…To study these pulsations more deeply, we employed ultrafast magnetic resonance encephalography (MREG) to capture complex-valued 4D fMRI brain data at a critical 10 Hz sampling rate in healthy volunteers during wakefulness and sleep. …”
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