Multimorbidity frailty index and clinical outcomes among 42,989 older heart failure patients directly discharged from emergency departments: A nationwide retrospective cohort study by Wan-Ju Liao, Hsi-Yu Lai, Liang-Yi Lin, Cheng-Hsueh Wu, Fei-Yuan Hsiao, Liang-Kung Chen

“…Readmission rates showed similar patterns. The severely frail group had higher risks of mortality (aHR 1.44, 95 % CI 1.33–1.55), all-cause readmissions (sHR 1.69, 95 % CI 1.62–1.76), and HF-related readmissions (sHR 1.59, 95 % CI 1.48–1.71). …”
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Farm households’ livelihood adaptive capacity under multiple pressures of small watershed management by Yaru Sun, Yilin Gan, Jing Luo, Tingting Han, Hafo Wang, Ruirui Yang, Lingling Tian

“…However, the FHLAC remains predominantly low to moderate in the small watershed. The contribution rates of livelihood pressure, livelihood capital, and willingness to adapt to FHLAC are 22.24 %, 28.69 %, and 49.07 %, respectively. …”
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Geospatial analysis of cholera outbreak in Lusaka, Zambia, between 2023 and 2024 by William Ngosa, Tadatsugu Imamura, Nyuma Mbewe, Joseph Seriki, Oscar Nzila, Fred Mfune, Godfrey Zulu, Chomba Mulando, Tizha Chiluba, Luo Miyanda, Agness Phiri, Lucy Sichone, Galion Mwape, Kapambwe Mulenga, Charles Chileshe, Nawa Mabuku, Dabwiso Banda, Fangyu Yan, Taro Kamigaki, Roma Chilengi, Nyambe Sinyange

“…Results Over the study period, 4,591 suspected cholera cases with geocoordinate data were identified, with incidence rates varying across the constituencies. Median cholera incidence (IQR) was 0.55 (0.27–1.44) in Lusaka, with higher incidence rates observed in unplanned residential areas. …”
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Molecular and genomic investigation of an urban outbreak of dengue virus serotype 2 in Angola, 2017-2019. by Zoraima Neto, Pedro A Martinez, Sarah C Hill, Domingos Jandondo, Julien Thézé, Marinela Mirandela, Renato Santana Aguiar, Joilson Xavier, Cruz Dos Santos Sebastião, Ana Luísa Micolo Cândido, Filipa Vaz, Gisel Reyes Castro, Joana Paula Paixão, Nicholas J Loman, Philippe Lemey, Oliver G Pybus, Jocelyne Vasconcelos, Nuno Rodrigues Faria, Joana de Morais

“…<h4>Background</h4>The transmission patterns and genetic diversity of dengue virus (DENV) circulating in Africa remain poorly understood. …”
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Dynamic parking space allocation at urban scale: Problem formulation and resolution by Hanae Errousso, Jihane El Ouadi, El Arbi Abdellaoui Alaoui, Siham Benhadou

“…To do this, we consider both solicitation rates in these areas and coverage ratios of received parking demands. …”
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The characteristics of new-onset myasthenia gravis after COVID-19 outbreak: a cross-sectional study by Yanzhen Huang, Yu Wu, Shaodan Zhou, Xianting Que, Ailing Jiang, Danli Shi, Ting Lu, Yanlan Chen, Ziqun Lin, Chao Liu, Yishuang Wen, Shuyi Zhang, Wen Huang

“…After COVID-19 outbreak, there was an increase in new-onset MG patients, with more cases occurring within the first three months. The rates of pulmonary inflammation (40.28%), COVID-19 vaccination (88.14%), and treatment with tacrolimus (15.98%) and MG duration (15 weeks, IQR: 5.75, 32) were higher, while rates of thymectomy (13.92%), baseline MG-ADL (3, IQR: 3, 6), and QMGS (7, IQR: 5,8) were lower compared to new-onset MG patients before COVID-19 outbreak. …”
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Distinctive lung cancer incidence trends among men and women attributable to the period effect in Shanghai: An analysis spanning 42 years by Li Xie, Ying Qian, Yishan Liu, Yixuan Li, Sinong Jia, Herbert Yu, Chunfang Wang, Biyun Qian, Pingping Bao

“…Methods Data were obtained from Shanghai Cancer Registry. Age‐standardized rates were calculated and average annual percent changes (AAPCs) were evaluated by Joinpoint regression. …”
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Electronic cigarette use in Saudi Arabia: a cross-sectional study on emerging trends and public health concerns by Farah Kais Alhomoud, Ayat Almuhayshi, Roqaia Altarouti, Tuqa Abushaheen, Faten Alhomoud, Noor Alotaibi, Dana Alsugeir, Khalid A. Alamer, Yousef Alqarni, Basmah Alfageh, Hailah Almoghirah, Fahad Alsulami

“…Socioeconomic factors such as lower income and education levels were associated with higher usage rates (p = 0.001 and p = 0.030, respectively). Dual users of e-cigarettes and traditional cigarettes made up 47% of participants, while 31% were ex-smokers, and 22% were exclusive e-cigarette users. …”
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Effects of PBAT biodegradable mulch on lettuce (Lactuca sativa L.) physiology and soil microbial community: Based on a long-term degradation trial by Weichang Gao, Zugui Tu, Xie Yin, Shuang Ming, Kai Cai

“…The relative abundances of the bacterial genus Chujaibacter and Pseudolabrys increased with high PBAT application rates. Beneficial fungi such as Amphinema and Trichoderma showed an increasing trend, while pathogenic fungi exhibited the opposite pattern. …”
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Prevalence and spectrum of PIK3 mutations in breast cancer and their correlation with clinicopathological features: A cross-sectional observational study from South India by HS Darling, Rahul Sud, Deep Kumar Raman

“…Conclusion: PIK3CA mutations are prevalent in Indian patients with breast cancer, with rates slightly higher than global estimates. High nodal burden and advanced-stage tumors showed greater mutation rates, which may have therapeutic implications.…”
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Whole Blood Stimulation Assay as a Treatment Outcome Monitoring Tool for VL Patients in Ethiopia: A Pilot Evaluation by Yetemwork Aleka, Ana Victoria Ibarra-Meneses, Meseret Workineh, Fitsumbrhan Tajebe, Amare Kiflie, Mekibib Kassa Tessema, Roma Melkamu, Azeb Tadesse, Javier Moreno, Johan van Griensven, Eugenia Carrillo, Wim Adriaensen

“…Current treatments produce variable rates of treatment failure and toxicity without sterile cure, rendering treatment efficacy monitoring essential. …”
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Geospatial Analytics of Urban Bus Network Evolution Based on Multi-Source Spatiotemporal Data Fusion: A Case Study of Beijing, China by Xiao Li, Shaohua Wang, Liang Zhou, Yeran Sun, Jiayi Zheng, Chang Liu, Junyuan Zhou, Cheng Su, Dachuan Xu

“…By analyzing spatial coverage rates of transit stations using road network and administrative division data, the study reveals the convenience of bus networks in different regions. …”
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The association between four dietary indices and mortality risk in cardiovascular disease patients by Mengshan Pan, Tongle Yin, Ying Yang, Feiyun Zhu, Jiamin Xu, Rucheng Chen, Weijun Zheng

“…Abstract Background The Planetary Healthy Diet Index-United States, the Healthy Diet Index, the Mediterranean Diet, and the Dietary Inflammation Index were linked to mortality rates in cardiovascular patients. This study investigated the relationship between these dietary patterns and all-cause mortality risk in U.S. cardiovascular patients from 2005 to 2006 to 2017–2018. …”
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Statistics and behavior of clinically significant extra-pulmonary vein atrial fibrillation sources: machine-learning-enhanced electrographic flow mapping in persistent atrial fibri... by Peter Ruppersberg, Steven Castellano, Philip Haeusser, Kostiantyn Ahapov, Melissa H. Kong, Stefan G. Spitzer, Stefan G. Spitzer, Georg Nölker, Andreas Rillig, Tamas Szili-Torok

“…Our machine learning approach established an activity threshold, above which divergent wavefront patterns—termed “significant sources”—predicted AF recurrence. …”
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Can Fire Season Type Serve as a Critical Factor in Fire Regime Classification System in China? by Huijuan Li, Sumei Zhang, Xugang Lian, Yuan Zhang, Fengfeng Zhao

“…Fire regime (FR) is a key element in the study of ecosystem dynamics, supporting natural resource management planning by identifying gaps in fire patterns in time and space and planning to assess ecological conditions. …”
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Integrative single‐cell transcriptomic analysis deciphers heterogeneous characteristics of gastrointestinal tract cancer by Chuwen Sun, Tong Li, Xin Jin, Zhihui Xiu, Hang Su, Huanming Yang, Ming Liu, Kui Wu

“…Abstract Background Gastrointestinal tract cancer (GIC), including oesophageal cancer (EC), gastric cancer (GC) and colorectal cancer (CRC), is characterised with high global incidence and mortality rates, with similar tumourigenic processes. However, the common and heterogeneous molecular features among GIC at single‐cell level remain poorly characterised. …”
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Pitfalls in the diagnosis of apparent homozygous mutations: two cases of IL10RA deficiency inflammatory bowel disease and a literature review by Xiu Shi, Ziqing Ye, Lai Qian, Wenhui Hu, Ye Yang, Chunmeng He, Zhiheng Huang, Bingbing Wu, Ying Huang

“…Abstract Background In East Asia, IL10RA is the predominant pathogenic gene in patients with very early-onset inflammatory bowel disease (VEO-IBD), frequently characterised by refractory diarrhoea and severe perianal disease, resulting in elevated death rates. IL10RA-deficient IBD, an autosomal recessive genetic disorder, has been documented to be inherited through the conventional compound heterozygous or homozygous mutation patterns from both parents. …”
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EFFECT OF NEURODEGENERATIVE CHANGES IN THE BRAIN ON THE FORMATION OF THE DISEASE CLINICAL PICTURE IN PATIENTS WITH MULTIPLE SCLEROSIS by L. N. Prakhova, Ye. P. Magonov, A. G. Ilves, A. A. Bogdan, G. V. Kataeva, Ye. S. Malakhova, Zh. I. Savintseva, I. D. Stolyarov, T. N. Trofimova

“…Neurodegenerative changes of brain structures evolve with different rates, have different intensity and determine the set of symptoms of neurological impairment and severity of disability, which indicates the presence of certain patterns of the process of atrophy in the brain, forming the clinical picture of the disease.…”
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Antimicrobial susceptibility profiles of thermophilic Campylobacter species from human, pig, and chicken feces in Rwanda by Noel Gahamanyi, Noel Gahamanyi, Arsene Musana Habimana, Jean Paul Harerimana, Josiane Mukayisenga, Salomon Ntwali, Anathali Umuhoza, Emmanuel Nsengiyumva, Emmanuel Irimaso, Jean Bosco Shimirwa, Cheol-Ho Pan, Erick Vitus Komba, Claude Mambo Muvunyi, Nadine Rujeni, Raghavendra G. Amachawadi

“…Multi-drug resistance (MDR) was observed among the isolates, with the highest rates observed in chicken isolates (88.0%). Proportions of MDR among pig (40.9%) and human (40.7%) isolates were more or less similar. …”
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Silent Revolution in Research for Sustainability by Bruce Alder

“…A variety of new arrangements have come into existence that promote international collaboration, including Horizon 2020 with its emphasis on societal challenges, the Bill &amp; Melinda Gates Foundation which has inspired a family of grand challenges funds on health and development, and the Future Earth joint program of research for global sustainability. …”
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