Intra-familial transmission of Hepatitis B virus in a peri-urban community from the Democratic Republic of the Congo by Florence Cindibu Kalonji, Yu Nakagama, Evariste Tshibangu-Kabamba, Nadine Kayiba Kalenda, Shun Nakagama, Sachie Nakagama, Pathy Kamanga Nkolongo, Nestor Kalala-Tshituka, Alphonse Lufuluabu Mpemba, Faustin Ndjibu Mpoji, André Kabongu Kalala, Benjamin Muamba Mpoyi, Dieudonné Mumba Ngoyi, Natsuko Kaku, Yusuke Shimakawa, Ghislain Tumba Disashi, Yasutoshi Kido

“…The overall HBsAg prevalence was 3.8% [95% CI 2.6–5.7], with the highest rate (10.1% [95% CI 4.9–18.2]) found in children aged 5 years and younger. …”
Get full text

A mobile app to improve adherence to colorectal cancer screening and post polypectomy surveillance guidelines by María A. Casas, Francisco Schlottmann, Leandro Steinberg, Xavier Bessa, Anna Serradesanferm, Angels Pozo, Sonia Torres, Antoni Castells, Francesc Balaguer, Jaume Grau, Lisandro Pereyra, María Pellisé

“…The app was increasingly and repeatedly used by professionals during the study period (72% retention rate). Among screening consultations, 2,082 (68.2%) patients were classified as average risk, suggesting the use of fecal occult blood test (FOBT) instead of colonoscopy. …”
Get full text

Early-stage endometrioid carcinoma with MSH6 protein deficiency: pitfalls in the diagnostic interpretation of microsatellite instability by Cheng Wang, Cheng Wang, Dongni Liang, Dongni Liang, Wei Wang, Wei Wang, Wei Kuang, Wei Kuang, Juan Zou, Juan Zou, Jing Zeng, Jing Zeng, Min Feng, Min Feng

“…This atypical MSI pattern is often overlooked, potentially increasing the risk of underdiagnosis of LS.…”
Get full text

The diagnostic utility of lung ultrasound in the assessment of interstitial lung disease associated with rheumatoid arthritis by Shaoyu Zheng, Zexuan Zhou, Guangzhou Du, Qingzi Chen, Shaoqi Chen, Jianqun Lin, Shijian Hu, Weijin Zhang, Kedi Zheng, Jinghua Zhuang, Meigan Huang, Barbara Ruaro, Cosimo Bruni, Anna-Maria Hoffmann-Vold, Marco Matucci-Cerinic, Daniel E. Furst, Yukai Wang

“…Sonographic ILD was detected in 76 patients who underwent LUS examination. The concordance rate between two modalities was 83.33% (Kappa value = 0.64, 95% CI 0.50–0.78). …”
Get full text

Analysis of HBV infection characteristics and OBI prevalence in pregnant women: a focus on HBcAb + alone or in combination with HBeAb + subgroups in Northwest China by Yun Xie, Ru Kang, Xiaoyue Cheng, Dan Li, Qi Wang, Jiao Li, Xuan Guo, Wenhui Gao, Xin He, Liutong Jiang, Gaili Meng

“…Despite a decline in HBsAg positivity, HBV remains moderately prevalent, the persistently high HBV susceptibility rate (31.07%) underscores an urgent need for targeted vaccination efforts among women of childbearing age in Northwest China.…”
Get full text

Strata pressure behavior law and regional-level intelligent early warning for high-intensity mining in extended working faces of medium-thick coal seams in Yuheng mining area by Feng CUI, Cheng ZONG, Xingping LAI, Tao XIE, Yunhu BAI, Yi ZHANG, Chong JIA, Hao WANG, Zhong LUO, Hao LIU

“…High-intensity mining and extended working faces have significantly modified strata pressure manifestation patterns and triggered spatiotemporal evolution of mining-induced pressure. …”
Get full text

Prevalence, microbiology, and antimicrobial susceptibility profile of bacterial skin and soft tissue infections in pediatric patients with malignancies at a referral teaching hospi... by Seyed Reza Abdipour Mehrian, Fatemeh Noushadi, Yaser Pourasghar, Armina Farkarian, Elahe Meftah, Fatemeh Homayounifar, Ali Amanati

“…However, it is important to acknowledge that this study was conducted at a single center and the high rate of culture-negative results suggests that non-bacterial etiologies or prior antibiotic use may play a significant role. …”
Get full text

Amivantamab versus standard therapies among patients with advanced non-small cell lung cancer and epidermal growth factor receptor exon 20 insertion mutations after platinum-based... by Lan Shen, Guangyuan Hu, Yan Wang, Jing Zhao, Xin Li, Jianmin Zhuo, Grace Kah Mun Low, Shun Lu

“…Effectiveness comparison, including real-world progression-free survival (rwPFS), real-world time to next therapy (rwTTNT) and real-world objective response rate (rwORR) was conducted between CHRYSALIS patients and the EC. …”
Get full text

The effect of photodynamic therapy on the wound process dynamics in patients with purulent hand diseases by J. L. Chepurnaya, G. G. Melkonyan, N. T. Gul’muradova, A. A. Sorokin

“…Photodynamic therapy was performed on the second postsurgical day by a laser apparatus “Atkus-2” (wave length 661 nm) with a gel form of the chlorinseries photosensitizer photoditazin in the form of an application at the rate of 1 g ml per 3–5 cm2 of the wound surface. …”
Get full text

Probabilistic seasonal dengue forecasting in Vietnam: A modelling study using superensembles. by Felipe J Colón-González, Leonardo Soares Bastos, Barbara Hofmann, Alison Hopkin, Quillon Harpham, Tom Crocker, Rosanna Amato, Iacopo Ferrario, Francesca Moschini, Samuel James, Sajni Malde, Eleanor Ainscoe, Vu Sinh Nam, Dang Quang Tan, Nguyen Duc Khoa, Mark Harrison, Gina Tsarouchi, Darren Lumbroso, Oliver J Brady, Rachel Lowe

“…As a climate-sensitive disease, environmental conditions and past patterns of dengue can be used to make predictions about future outbreak risk. …”
Get full text

Deep learning and genomic best linear unbiased prediction integration: An approach to identify potential nonlinear genetic relationships between traits by F. Shokor, P. Croiseau, H. Gangloff, R. Saintilan, T. Tribout, T. Mary-Huard, B.C.D. Cuyabano

“…When applied to a real dataset from the French Holstein dairy cattle population, DLGBLUP detected nonlinear genetic relationships between pairs of traits, such as conception rate and protein content, and SCC and fat yield, although, no significant increase in prediction accuracy was observed. …”
Get full text

Longitudinal Digital Phenotyping of Multiple Sclerosis Severity Using Passively Sensed Behaviors and Ecological Momentary Assessments: Real-World Evaluation by Zongqi Xia, Prerna Chikersal, Shruthi Venkatesh, Elizabeth Walker, Anind K Dey, Mayank Goel

“…Smartphone sensors recorded call activity, location, and screen use, while fitness trackers captured heart rate, sleep patterns, and step count. We extracted patient-level behavioral features and categorized them into 2 feature sets: one from the prediction period (called action) and one from the preceding period (called context). …”
Get full text

Population immunity to SARS-CoV-2 virus in residents of the Irkutsk Region in the dynamics of the epidemic by S. V. Balakhonov, V. I. Dubrovina, M. V. Chesnokova, D. D. Bryukhova, N. O. Kiseleva, A. B. Pyatidesyatnikova, K. M. Korytov, V. V. Voitkova, A. N. Perezhogin, T. A. Gavrilova, A. A. Seledtsov

“…In this regard, the study of the manifestations of the epidemic process of the new coronavirus infection COVID-19 and the patterns of its development are an urgent area of research. …”
Get full text

Groundwater rebound and seepage characteristics and water quality evolution in a sealed mining area in North China type coalfield by Huiyong YIN, Dehui SUN, Fangying DONG, Fanhua WANG, Lifeng ZHANG, Tao WU, Chao LIU, Yifan ZENG

“…After the goaf sealing, water-rock interactions persisted during the reinjection of the accumulated water, but the cation exchange rate slowed down. The mineral phases showed similar but weakened variation trends compared to the water inrush stage. …”
Get full text

Dynamics of changes in population immunity to the SARS-CоV-2 virus in residents the Irkutsk region in the context of the COVID-19 pandemic by S. V. Balakhonov, V. I. Dubrovina, A. B. Pyatidesyatnikova, D. D. Briukhova, N. O. Kiseleva, K. M. Korytov, V. V. Voitkova, A. N. Perezhogin, M. V. Chesnokova, T. A. Gavrilova, A. A. Seledtcov

“…A comprehensive study of the patterns of development and manifestations of the epidemic process of the new coronavirus infection COVID-19 is an urgent line of research. …”
Get full text

A first large study of whole-exome sequencing (WES) in 489 patients with suspected rare genetic disorders at a tertiary centre in Malaysia by Lip Hen Moey, Go Hun Seo, Boon Eu Cheah, Wee Teik Keng, Hane Lee, Gaik Siew Ch’ng

“…Introduction: Rare genetic disorders occur at a rate of 40–82 per 1000 live births worldwide. Identifying the molecular cause of rare genetic disorders is beneficial because it allows early diagnosis, facilitates treatment planning and provision of accurate genetic counselling. …”
Get full text

Glycogen depletion in astrocytes induces sex-dimorphic remodeling of astrocytic and synaptic structures with concomitant anxiety-like behaviors and maternal care deficits by Xiaotong Shi, Yuanyuan Zhu, Zhaoyichun Zhang, Ningcan Ma, Danyi He, You Wu, Ziyi Dai, Xinyan Qin, Yingyi Chen, Youyi Zhao, Haopeng Zhang, Jing Huang, Hui Zhang, Ze Fan

“…Maternal care was analyzed through pup retrieval assays and nest-building behavior, while offspring development was tracked via survival rates and ultrasonic vocalizations. Expression of hormonal receptors was identified via qPCR and immunofluorescence staining. …”
Get full text

A multicellular self-organized probiotic platform for oral delivery enhances intestinal colonization by Hua Liu, Zhijie Chen, Qiaowen Lin, Yi Chen, Liwen Hong, Jie Zhong, Zhengwei Cai, Zhengting Wang, Wenguo Cui

“…In vivo, the EMS strategy exhibits 89- and 52-fold higher colonization rate in the cecum and colon of mice, compared to conventional oral probiotics. …”
Get full text

A Comprehensive Survey of Research Trends in mmWave Technologies for Medical Applications by Xiaoyu Zhang, Chuhui Liu, Yanda Cheng, Zhengxiong Li, Chenhan Xu, Chuqin Huang, Ye Zhan, Wei Bo, Jun Xia, Wenyao Xu

“…We introduce a taxonomy that decouples low-level mmWave signal features—such as motion, material property, and structure—from high-level biomedical biomarkers, including respiration pattern, heart rate, tissue hydration, and gait. We then classify and contrast the modeling approaches—ranging from physics-driven analytical models to machine learning techniques—that enable this mapping. …”
Get full text

China’s efforts on the CSEP and a retrospective case by Huaizhong Yu, Jingxue Zhang, Yue Liu, Yongxian Zhang, Chieh-Hung Chen, Rui Yan, Gang Li, Zeping Li, Yuchuan Ma, Zhengyi Yuan, Wen Yang, Donghui Jia, Binbin Zhao

“…In addition, several new methods, such as Crustal Vibration (CV), State Vector (SV), Earthquake Occurrence Rate (EOR), and Seismic Modulation Ratio (SMR) have also been involved. …”
Get full text