Sentiment Analysis Using a Large Language Model–Based Approach to Detect Opioids Mixed With Other Substances Via Social Media: Method Development and Validation by Muhammad Ahmad, Ildar Batyrshin, Grigori Sidorov

“… Abstract BackgroundThe opioid crisis poses a significant health challenge in the United States, with increasing overdoses and death rates due to opioids mixed with other illicit substances. …”
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The relationship between immune cell infiltration and necroptosis gene expression in sepsis: an analysis using single-cell transcriptomic data by Shouyi Wang

“…It remains a significant medical challenge due to its high mortality rates and requires a deeper understanding of its underlying mechanisms. …”
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“Prevalence of disordered eating and eating disorders among Norwegian university students before and after the COVID-19 pandemic, 2018 and 202.: The SHoT study.” by Lisa Marie Jacobsen, Gørill Haugan, Gina Dimitropoulos, Amelia Austin, Børge Sivertsen, Tonje Braaten, Ottar Bjerkeset

“…Results From 2018 to 2022, the prevalence of self-reported EDs increased among females (3.5% in 2018 and 4.5% in 2022) and males (0.4% in 2018 and 0.6% in 2022), while gender-diverse students exhibited the overall highest ED rates (around 10% in both surveys). Anorexia nervosa remained the most common ED among females. …”
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Prevalence of Dal blood type and dog erythrocyte antigens 1 and 4 among canine blood donors and recipients in Seoul, South Korea by Hyouju Kim, Hyun-Jung Han

“…The prevalence of DEA 1 observed in this study (70.48%) is consistent with prior studies; however, Dal and DEA 4 exhibited lower prevalence rates than those reported in Europe and North Americas, with Dal at 77.14% (compared to 89.3–100%) and DEA 4 at 92.38% (compared to 98.8–100%). …”
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Functional Connectivity Biomarker Extraction for Schizophrenia Based on Energy Landscape Machine Learning Techniques by Janerra D. Allen, Sravani Varanasi, Fei Han, L. Elliot Hong, Fow-Sen Choa

“…However, significant patient and control differences were found for the brief psychiatric rating scale (BPRS), auditory perceptual trait and state (APTS), visual perceptual trait and state (VPTS), working memory score, and processing speed score. …”
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Solar dryers: A review of mechanism, methods and critical analysis of transport models applicable in solar drying of product by Onyinyechi Nnamchi, Cyprian Tom, Godwin Akpan, Murphy Umunna, David Ubong, Mathew Ibeh, Adindu Linus–Chibuezeh, Leonard Akuwueke, Stephen Nnamchi, Augustine Ben, Macmanus Ndukwu

“…Solar drying has been demonstrated to be a sustainable and eco-friendly drying process for drying and preserving agricultural products, offering advantages over traditional methods that include faster drying rates, improved product quality, and reduced energy costs. …”
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Assessing Natural Variation as a Baseline for Biodiversity Monitoring: The Case of an East Mediterranean Canyon by Meir Finkel, Ariel Leib Leonid Friedman, Hagar Leschner, Ben Cohen, Hoshen Inbar, Shai Gelbert, Agam Rozen, Eitan Barak, Ido Livne, Ittai Renan, Gilad Ben-Zvi, Orr Comay

“…Despite substantial species turnover rates between periods in all the taxa, almost no change was found regarding the biogeographical origins of plant and beetle species composition. …”
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Deep learning enhanced road traffic analysis: Scalable vehicle detection and velocity estimation using PlanetScope imagery by Maciej Adamiak, Yulia Grinblat, Julian Psotta, Nir Fulman, Himshikhar Mazumdar, Shiyu Tang, Alexander Zipf

“…Satellite-based approaches provide broad spatial coverage, but face challenges, including high costs, low frame rates, and difficulty detecting small vehicles in medium-resolution imagery. …”
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Effect of cholesterol on distribution, cell uptake, and protein corona of lipid microspheres at sites of cardiovascular inflammatory injury by Lingyan Li, Xingjie Wu, Qianqian Guo, Yu'e Wang, Zhiyong He, Guangqiong Zhang, Shaobo Liu, Liping Shu, Babu Gajendran, Ying Chen, Xiangchun Shen, Ling Tao

“…Then, the slow cellular uptake rate observed for CH@LM contributed to a prolonged duration of drug efficacy. …”
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Ten-year trends in opioid prescribing and vaso-occlusive crises in sickle cell disease: a population-based national cohort study (2011–2022)Research in context by Kevin Y. Xu, Terri V. Newman, Lakeya S. McGill, Enrico M. Novelli, Cheryl A. Hillery, Joanna L. Buss, Lisa Gong, Ruizhi Huang, Fanghong Dong, Dustin Stwalley, Joanne Salas, Shiyuan A. Liu, Jeffrey F. Scherrer, Tashalee R. Brown, Tae Woo Park, Marc R. LaRochelle, Richard A. Grucza, Charles R. Jonassaint

“…Primary outcomes were monthly rates of outpatient opioid prescriptions and VOC-related acute care encounters. …”
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Antitumor power of oncolytic HSV engineered with IL-12 and IL-15 by Lei Zhang, Yanbin Zhu, Kunpeng Zheng, Xinyu Zhang, Chunxue Fu, Dan Wang, Xinqiang Zhang, Tong Wu, Shuxin Han, Zhenghai Ma

“…Treatment with RG2006 significantly reduced tumor growth and extended survival rates compared to other forms of oHSV-1. Analyses indicated a marked elevation in T cell and NK cell activation in mice receiving RG2006. …”
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<i>SHROOM3</i> Deficiency Aggravates Adriamycin-Induced Nephropathy Accompanied by Focal Adhesion Disassembly and Stress Fiber Disorganization by Li-Nan Xu, Ying-Ying Sun, Yan-Feng Tan, Xin-Yue Zhou, Tian-Chao Xiang, Ye Fang, Fei Li, Qian Shen, Hong Xu, Jia Rao

“…Clinically, the glomerular <i>SHROOM3</i> expression positively correlated with glomerular filtration rates in focal segmental glomerulosclerosis patients. …”
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Satellite-Based Prediction of Water Turbidity Using Surface Reflectance and Field Spectral Data in a Dynamic Tropical Lake by Elsa Pereyra-Laguna, Valeria Ojeda-Castillo, Enrique J. Herrera-López, Jorge del Real-Olvera, Leonel Hernández-Mena, Ramiro Vallejo-Rodríguez, Jesús Díaz

“…In this study, we utilized Landsat satellite imagery in conjunction with near-synchronous in situ reflectance measurements to monitor spatial and seasonal turbidity patterns between 2023 and 2025. The surface reflectance was radiometrically corrected and validated using spectroradiometer data collected across eight sampling sites in the eastern sector of the lake, the area where the highest rates of horizontal change in turbidity occur. …”
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Nutritional status, body indices, and somatotype in Aymara and Quechua children from high Andean areas of Peru by Lidia Sofia Caballero Gutiérrez, Rodolfo Adrian Núñez Postigo, Juber Chávez Dominguez, Vilma Lucrecia Tapia Aguirre, José Oscar Alberto Begazo Miranda

“…Among the findings, most children presented normal nutritional status according to BMI-for-age and height-for-age Z-scores. However, high rates of overweight and obesity were observed in Aymara (39%) and Quechua (28.4%) children, with differences in fat content between ethnic groups at the 5th, 10th, 50th, and 75th percentiles. …”
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The role of city parks in creating ‘wellbeing societies’: A case study of Piłsudski Park in Łódź, Poland by Melanie Kay Smith, Joanna Kowalczyk-Anioł, Jakub Janiszewski, Karolina Grabarczyk

“…Although social interactions are rated lower overall, they are particularly significant for younger and older users, as well as marginalized groups such as unemployed individuals. …”
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Mutation Profiling of Premalignant Colorectal Neoplasia by Jakub Karczmarski, Krzysztof Goryca, Jacek Pachlewski, Michalina Dabrowska, Kazimiera Pysniak, Agnieszka Paziewska, Maria Kulecka, Malgorzata Lenarcik, Andrzej Mroz, Michal Mikula, Jerzy Ostrowski

“…HGD adenomas had significantly higher mutation rates than LGD adenomas, while LGD-H adenomas exhibited mutation frequencies similar to those of LGD adenomas. …”
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Real-world effectiveness and safety of CDK4/6i in elderly and BIPOC patients with HR+/HER2- advanced/metastatic breast cancer: an updated systematic literature review by Nadia Harbeck, Adam Brufsky, Chloe Grace Rose, Beata Korytowsky, Connie Chen, Krista Tantakoun, Endri Jazexhi, Do Hoang Vien Nguyen, Meaghan Bartlett, Imtiaz A. Samjoo, Timothy Pluard

“…Key outcomes for synthesis were effectiveness, treatment patterns, and safety.ResultsThis review included 23 unique studies. …”
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Improvement of Oral Anticoagulant Prescription and Long‐Term Clinical Outcomes of Patients With Atrial Fibrillation After Implementation of a Clinical Decision Support System in Ou... by Po‐Tseng Lee, Mu‐Hsiang Huang, Ting‐Chun Huang, Pi‐Shan Sung, Chi‐Hui Hsu, Ya‐Ling Huang, Sheng‐Hsian Lin, Ping‐Yen Liu

“…Results OAC prescription rates increased from 47.3% to 67.5% after CDSS implementation. …”
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Exploring mobility data for enhancing HIV care engagement in Black/African American and Hispanic/Latinx individuals: a longitudinal observational study protocol by Katherine P Theall, Lisa Hightow-Weidman, Xiaoming Li, Sean Young, Lidia Flores, Seungjun Kim, Maryam Hassani, Cristina De Haro, Mohamed Emish, Zeyad Kelani, Dominic Arjuna Ugarte, Amanda Castel

“…Mobility data that measure individuals’ movements over time in combination with sociostructural data (eg, crime, census) can potentially identify barriers and facilitators to HIV care engagement and can enhance public health surveillance and inform interventions.Methods and analysis The proposed work is a longitudinal observational cohort study aiming to enrol 400 Black/African American and Hispanic/Latinx individuals living with HIV in areas of the USA with high prevalence rates of HIV. Each participant will be asked to share at least 14 consecutive days of mobility data per month through the study app for 1 year and complete surveys at five time points (baseline, 3, 6, 9 and 12 months). …”
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Lignin Unlocks Stealth Carbon Sinks in Cold Seeps via Microbial Enzymatic Gatekeeping by Jialing Li, Jingchun Feng, Pandeng Wang, Mengzhuo Zhu, Yongji Huang, Ying Wu, Junning Fan, Junlin Hu, Xiyang Dong, Yingli Zhou, Xuanyu Tao, Si Zhang

“…Our findings establish 3 paradigm shifts: (a) The turnover rates of terrestrial organic carbon are likely underestimated in deep-sea ecosystems; (b) microbial consortia employ combinatorial enzymatic strategies distinct from terrestrial decomposition regimes; (c) methyl shunting from lignin breakdown primes methanogenic precursors, revealing cryptic linkages between refractory carbon cycling and greenhouse gas reservoirs.…”
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