Risk factors for adverse prognosis and death in American visceral leishmaniasis: a meta-analysis. by Vinícius Silva Belo, Claudio José Struchiner, David Soeiro Barbosa, Bruno Warlley Leandro Nascimento, Marco Aurélio Pereira Horta, Eduardo Sérgio da Silva, Guilherme Loureiro Werneck

“…<h4>Background</h4>In the current context of high fatality rates associated with American visceral leishmaniasis (VL), the appropriate use of prognostic factors to identify patients at higher risk of unfavorable outcomes represents a potential tool for clinical practice. …”
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Pathogen-specific epitopes as epidemiological tools for defining the magnitude of Mycobacterium leprae transmission in areas endemic for leprosy. by Marcia V S B Martins, Marjorie M da S Guimarães, John S Spencer, Mariana A V B Hacker, Luciana S Costa, Fernanda M Carvalho, Annemieke Geluk, Jolien J van der Ploeg-van Schip, Maria A A Pontes, Heitor S Gonçalves, Janvier P de Morais, Tereza J P G Bandeira, Maria C V Pessolani, Patrick J Brennan, Geraldo M B Pereira

“…This subset of M. leprae-specific peptides allowed the differentiation of groups of individuals from sites hyperendemic for leprosy versus those from areas with lower level detection rates. A progressive reduction in the IFN-γ levels in response to the peptides was seen when contacts of multibacillary (MB) patients were compared to other less exposed groups, suggesting a down modulation of IFN-γ production with an increase in bacillary load or exposure to M. leprae. …”
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Resource-Oriented Treatment Technologies for Rural Domestic Sewage in China Amidst Population Shrinkage: A Case Study of Heyang County in Guanzhong Region, Shaanxi Province by Mei Huang, Degang Duan, Sicheng Tan, Ling Huang

“…Traditional centralized sewage treatment models face issues in cost-effectiveness, facility utilization rates, and sustainable maintenance, necessitating the exploration of adaptive governance technologies under new demographic conditions. …”
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Temporal and spatial interactions in sympatric ungulates: Insights from Japanese serow and sika deer. by Tomoki Mori, Kensuke Miura, Hiroyuki Takeuchi, Yasuaki Niizuma

“…Nevertheless, during autumn, reduced activity overlap rates, when the relative abundance index (RAI) of sika deer increased, may indicate that Japanese serow have modified their behavior to minimize resource competition. …”
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Numerical investigation of cooling enhancement in double-layer fractal-like microchannel disk heat sinks via layer shifting and tertiary channels by Hosein Akhtari, Ardalan Shafiei Ghazani

“…The thermal and hydrodynamic performance of these enhanced designs is numerically evaluated and compared with single-layer and standard double-layer configurations under heat fluxes of 40, 60, and 80 W/cm² and inlet flow rates from 300 to 600 ml/min. While double layering effectively reduces pressure drop by redistributing the coolant flow, integrating tertiary microchannels leads to an additional ∼1.5 % drop due to reduced velocity and wall shear stress. …”
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Aeroelastic Oscillations of Cantilever Beams Reinforced by Carbon Nanotubes Based on a Modified Third-Order Piston Theory by Mehdi Alimoradzadeh, Francesco Tornabene, Rossana Dimitri

“…Moreover, higher Mach numbers and greater thickness ratios significantly amplify both frequency response and lateral deflections, although damping rates tend to decrease. These findings provide valuable insights into the optimization of CNTR composite structures for advanced aeroelastic applications under supersonic conditions, as useful for many engineering applications.…”
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The global, regional, and national impact of laryngeal cancer from 1990 to 2021, along with forecasts for 2050: a comprehensive analysis for the Global Burden of Disease 2021 resea... by Tingting Duan, Yuxia Zou, Xuan Liu, Yue Du, Ruihu Li, Jingxiang Cai, Jumei Li, Xiaofeng Wang, Xuejun Zhou, Shun Ding

“…The incidence and mortality rates of male patients are much higher than those of female patients, and the gap between men and women gradually narrows after the age of 70. …”
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Prominent Zakat Institutions and Their Role in Advancing the Welfare of the Muslim Community in The Eastern Province of Sri Lanka by Raseethu Mohamed Kasjin

“…Findings: The study highlights varying growth rates in Zakat collection and fluctuations across regions, with some Zakat fund collections experiencing sharp increases. …”
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Simulation of the impacts of high temperature stress on pepper (Capsicum annum L.) yields by Bomi Park, Sojung Kim, Sumin Kim

“…PHR23, having a larger leaf area, accumulated more biomass than fruit yields in the initial month of exposure, thus increasing its yields at higher temperature conditions due to enhanced photosynthesis rates. The crop growth curve and parameters were formulated based on these studies, and the open field simulations were calibrated with measured yields from multiple locations in South Korea from 2020-2024. …”
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Impact of post-transplant cyclophosphamide with bendamustine on immune reconstitution in young patients undergoing T-cell replete haploidentical bone marrow transplantation: result... by Forrest L. Baker, Forrest L. Baker, Forrest L. Baker, Jessica Stokes, Megan J. Cracchiolo, Dan Davini, Richard J. Simpson, Richard J. Simpson, Richard J. Simpson, Richard J. Simpson, Emmanuel Katsanis, Emmanuel Katsanis, Emmanuel Katsanis, Emmanuel Katsanis

“…Multi-parameter flow cytometry and TCR β sequencing of genomic DNA was performed on isolated PBMCs on PT days +30, +60, +100, +180, and +365.ResultsOverall, the PT-CY/BEN (n=14) regimen was associated with earlier neutrophil and platelet engraftment, reduced transfusion requirements, and comparable clinical outcomes to PT-CY (n=10), including survival and relapse rates. PT-CY/BEN patients exhibited distinct immune reconstitution patterns, characterized by earlier CD4+ T-cell recovery, impaired CD8+ T-cell engraftment, and reduced NK-cell counts. …”
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Multimorbidity frailty index and clinical outcomes among 42,989 older heart failure patients directly discharged from emergency departments: A nationwide retrospective cohort study by Wan-Ju Liao, Hsi-Yu Lai, Liang-Yi Lin, Cheng-Hsueh Wu, Fei-Yuan Hsiao, Liang-Kung Chen

“…Readmission rates showed similar patterns. The severely frail group had higher risks of mortality (aHR 1.44, 95 % CI 1.33–1.55), all-cause readmissions (sHR 1.69, 95 % CI 1.62–1.76), and HF-related readmissions (sHR 1.59, 95 % CI 1.48–1.71). …”
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Farm households’ livelihood adaptive capacity under multiple pressures of small watershed management by Yaru Sun, Yilin Gan, Jing Luo, Tingting Han, Hafo Wang, Ruirui Yang, Lingling Tian

“…However, the FHLAC remains predominantly low to moderate in the small watershed. The contribution rates of livelihood pressure, livelihood capital, and willingness to adapt to FHLAC are 22.24 %, 28.69 %, and 49.07 %, respectively. …”
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Geospatial analysis of cholera outbreak in Lusaka, Zambia, between 2023 and 2024 by William Ngosa, Tadatsugu Imamura, Nyuma Mbewe, Joseph Seriki, Oscar Nzila, Fred Mfune, Godfrey Zulu, Chomba Mulando, Tizha Chiluba, Luo Miyanda, Agness Phiri, Lucy Sichone, Galion Mwape, Kapambwe Mulenga, Charles Chileshe, Nawa Mabuku, Dabwiso Banda, Fangyu Yan, Taro Kamigaki, Roma Chilengi, Nyambe Sinyange

“…Results Over the study period, 4,591 suspected cholera cases with geocoordinate data were identified, with incidence rates varying across the constituencies. Median cholera incidence (IQR) was 0.55 (0.27–1.44) in Lusaka, with higher incidence rates observed in unplanned residential areas. …”
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Molecular and genomic investigation of an urban outbreak of dengue virus serotype 2 in Angola, 2017-2019. by Zoraima Neto, Pedro A Martinez, Sarah C Hill, Domingos Jandondo, Julien Thézé, Marinela Mirandela, Renato Santana Aguiar, Joilson Xavier, Cruz Dos Santos Sebastião, Ana Luísa Micolo Cândido, Filipa Vaz, Gisel Reyes Castro, Joana Paula Paixão, Nicholas J Loman, Philippe Lemey, Oliver G Pybus, Jocelyne Vasconcelos, Nuno Rodrigues Faria, Joana de Morais

“…<h4>Background</h4>The transmission patterns and genetic diversity of dengue virus (DENV) circulating in Africa remain poorly understood. …”
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Dynamic parking space allocation at urban scale: Problem formulation and resolution by Hanae Errousso, Jihane El Ouadi, El Arbi Abdellaoui Alaoui, Siham Benhadou

“…To do this, we consider both solicitation rates in these areas and coverage ratios of received parking demands. …”
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The characteristics of new-onset myasthenia gravis after COVID-19 outbreak: a cross-sectional study by Yanzhen Huang, Yu Wu, Shaodan Zhou, Xianting Que, Ailing Jiang, Danli Shi, Ting Lu, Yanlan Chen, Ziqun Lin, Chao Liu, Yishuang Wen, Shuyi Zhang, Wen Huang

“…After COVID-19 outbreak, there was an increase in new-onset MG patients, with more cases occurring within the first three months. The rates of pulmonary inflammation (40.28%), COVID-19 vaccination (88.14%), and treatment with tacrolimus (15.98%) and MG duration (15 weeks, IQR: 5.75, 32) were higher, while rates of thymectomy (13.92%), baseline MG-ADL (3, IQR: 3, 6), and QMGS (7, IQR: 5,8) were lower compared to new-onset MG patients before COVID-19 outbreak. …”
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Distinctive lung cancer incidence trends among men and women attributable to the period effect in Shanghai: An analysis spanning 42 years by Li Xie, Ying Qian, Yishan Liu, Yixuan Li, Sinong Jia, Herbert Yu, Chunfang Wang, Biyun Qian, Pingping Bao

“…Methods Data were obtained from Shanghai Cancer Registry. Age‐standardized rates were calculated and average annual percent changes (AAPCs) were evaluated by Joinpoint regression. …”
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Effects of PBAT biodegradable mulch on lettuce (Lactuca sativa L.) physiology and soil microbial community: Based on a long-term degradation trial by Weichang Gao, Zugui Tu, Xie Yin, Shuang Ming, Kai Cai

“…The relative abundances of the bacterial genus Chujaibacter and Pseudolabrys increased with high PBAT application rates. Beneficial fungi such as Amphinema and Trichoderma showed an increasing trend, while pathogenic fungi exhibited the opposite pattern. …”
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Geospatial Analytics of Urban Bus Network Evolution Based on Multi-Source Spatiotemporal Data Fusion: A Case Study of Beijing, China by Xiao Li, Shaohua Wang, Liang Zhou, Yeran Sun, Jiayi Zheng, Chang Liu, Junyuan Zhou, Cheng Su, Dachuan Xu

“…By analyzing spatial coverage rates of transit stations using road network and administrative division data, the study reveals the convenience of bus networks in different regions. …”
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EFFECT OF NEURODEGENERATIVE CHANGES IN THE BRAIN ON THE FORMATION OF THE DISEASE CLINICAL PICTURE IN PATIENTS WITH MULTIPLE SCLEROSIS by L. N. Prakhova, Ye. P. Magonov, A. G. Ilves, A. A. Bogdan, G. V. Kataeva, Ye. S. Malakhova, Zh. I. Savintseva, I. D. Stolyarov, T. N. Trofimova

“…Neurodegenerative changes of brain structures evolve with different rates, have different intensity and determine the set of symptoms of neurological impairment and severity of disability, which indicates the presence of certain patterns of the process of atrophy in the brain, forming the clinical picture of the disease.…”
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