Comparing survival outcomes of anti-fibrotic therapy for idiopathic pulmonary fibrosis with and without emphysema: a multi-center real-world study from Taiwan by Yu-Hung Fang, Yi-An Hsieh, Yen-Fu Chen, Yu-Chi Chiu, Yu-Ching Lin, Kuo-Tung Huang, Yung-Chia Huang, Yu-Feng Wei, Chien-Wen Huang, Pin-Kuei Fu, Taiwan Multi-Centre Interstitial Lung Disease Research Consortium

“…During a median follow-up of 3.7 years, the overall survival rates were comparable (IPF only: 45.6%; IPF with emphysema: 48.4%). …”
Get full text

IMPACT OF THE INFLAMMATORY AND ISCHEMIC HEART DISEASE MARKERS INTO THE OVERALL CARDIOVASCULAR MORTALITY IN SENILE CITIZENS OF A LARGE CITY (THE DATA FROM SAHR TRIAL) by S. A. Shalnova, S. E. Evstifeeva, A. D. Deev, V. A. Metelskaya, A. V. Kapustina, G. A. Muromtseva, Yu. A. Balanova, E. M. Tuaeva, A. E. Imajeva, N. V. Kiseleva, M. A. Shkolnikova

“…For the assessment of current subclinical inflammation we used high-sensititvity C-reactive protein (hsCRP), interleucine 6 (IL-6), fibrinogen (FG), leucocytes, erythrocyte sedimentation rate (ESR). For CHD screening, we used standard ROse questionnaire and ECG pattern by Minnesota coding. …”
Get full text

A clinico-epidemiological study, assessing possible predictors of mortality and health-related quality of life for people living with visceral leishmaniasis – human immune virus (V... by Niyamat Ali Siddiqui, Dhruv Kumar Pandey, Ashish Kumar Singh, Sanjay Kumar Sinha, Mohd. Zahid Ansari, Rishikesh Kumar, Biplab Pal, Vidya Nand Rabi Das, Rajatashuvra Adhikary, Saurabh Jain, Krishna Pandey

“…These patients have a poor VL therapeutic success rate, more drug-related toxicity, and relapses resulting in high mortality. …”
Get full text

Clinical characteristics and outcomes of COVID-19 in kidney transplant recipients by R. O. Kantariya, Ya. G. Moysyuk, E. I. Prokopenko, A. R. Karapityan, A. A. Ammosov, A. V. Makevnina, A. A. Gaydarova

“…The comparison study of the clinical pattern, laboratory and instrumental test results, treatment features and outcomes was made.Results. …”
Get full text

Clinical profiles of SS-ILD compared with SS-NILD in a Chinese population: a retrospective analysis of 735 patients by Ting Guo, Yaomei Long, Qinxue Shen, Wei Guo, Wang Duan, Xiaoli Ouyang, Hong Peng

“…NSIP (56.3%) was the most frequent HRCT pattern. Compared with pSS patients with ILD (pSS-ILD) patients, sSS patients with ILD (sSS-ILD) patients had a higher incidence of proteinuria (p < .001) and hypercreatinaemia (p = .013), a higher level of erythrocyte sedimentation rate (ESR) (p = .003), low levels of complement 3 (C3) (p = .013), lymphocytes (p = .009) and leukocytes (p = .024), and worse DLCO (%Pred) (p = .035).Conclusions ILD is a common pulmonary involvement in both pSS patients and sSS patients. …”
Get full text

Supported Telemonitoring and Glycemic Control in People with Type 2 Diabetes: The Telescot Diabetes Pragmatic Multicenter Randomized Controlled Trial. by Sarah H Wild, Janet Hanley, Stephanie C Lewis, John A McKnight, Lucy B McCloughan, Paul L Padfield, Richard A Parker, Mary Paterson, Hilary Pinnock, Aziz Sheikh, Brian McKinstry

“…No significant differences were identified between groups in weight, treatment pattern, adherence to medication, or quality of life in secondary analyses. …”
Get full text

Immunological efficacy and tolerability of vaccination in patients with noncommunicable diseases by O. M. Drapkina, M. N. Mamedov, V. A. Kutsenko, L. N. Ryzhakova, A. V. Emelyanov, B. U. Mardanov, A. V. Kontsevaya

“…The following clinical and paraclinical investigations were carried out: saturation assessment, measurement of temperature, blood pressure and heart rate at rest, pharynx examination, auscultation of the heart and respiratory organs. …”
Get full text

The Role of Intestinal Translocation in the Pathogenesis of Pneumonia in Acute Poisoning and the Contribution of Intestinal Lavage to Its Prevention and Resolution by V. A. Matkevich, T. T. Tkeshelashvili, A. G. Vorobyova, N. E. Stolbova, M. M. Potskhveriya, Yu. S. Goldfarb

“…Mortality among the patients with PPD poisoning decreased by 7 times, and with M and CS poisoning, as well as with AlD, there were no deaths, while in the respective comparison groups, the mortality rate for pneumonia was 5.1, 7.4, and 17.4 %, respectively. …”
Get full text

An impact of neutrophil extracellular traps to the prothrombotic state and tumor progression in gynecological cancer patients by E. V. Slukhanchuk, V. O. Bitsadze, A. G. Solopova, J. Kh. Khizroeva, N. D. Degtyareva, D. V. Shcherbakov, J.-C. Gris, I. Elalamy, A. D. Makatsariya

“…One of the leading causes in the mortality pattern of cancer patients is accounted for by thrombotic complications. …”
Get full text

A COMPREHENSIVE APPROACH TO THE TREATMENT OF PATIENTS WITH ALVEOLAR RIDGE ATROPHY IN PARODONTAL DISEASES: FROM THE USE OF BONE AUGMENTATION TO THE RESTORATION OF FUNCTIONAL OCCLUS... by Yu.O. Kinash, L.V. Kinash, K.V. Honcharov

“… The rate of atrophy is significantly lower with the included dentition defects than with the final ones, as the teeth that limit the newly formed defect are natural constraints for bone resorption. …”
Get full text

Near-Unity Nitrate to Ammonia conversion via reactant enrichment at the solid-liquid interface by Wanru Liao, Jun Wang, Yao Tan, Xin Zi, Changxu Liu, Qiyou Wang, Li Zhu, Cheng-Wei Kao, Ting-Shan Chan, Hongmei Li, Yali Zhang, Kang Liu, Chao Cai, Junwei Fu, Beidou Xi, Emiliano Cortés, Liyuan Chai, Min Liu

Get full text

The optimal strategy for seasonal influenza vaccination to prevent high-intensity level of influenza epidemics in Zhejiang, China: an integrated transmission-dynamic and health-eco... by Mengsha Chen, Mengya Yang, Rui Yan, Zhengwei Liu, Can Chen, Rongrong Qu, Wenkai Zhou, Jiaxing Qi, Kexin Cao, Jiani Miao, Xiaoyue Wu, Jiaxin Chen, Qianqian Feng, HuiHui Zhang, Anqi Dai, Yi Yang, Jingtong Zhou, Qin Chen, Jimin Sun, Shigui Yang

“…Results Between 2018 and 2020, influenza incidence in Zhejiang Province followed typical seasonal patterns. However, during the COVID-19 pandemic, these patterns became irregular, culminating in a high-intensity influenza season in 2022–2023. …”
Get full text

Three‒Dimensional Numerical Simulation of the Breaching Process of Landslide Dams with Heterogeneous Structures by HU Xianrui, PENG Ming, FU Xiaoli, YANG Ge, ZHU Yan, SHI Zhenming, ZHANG Gongding

“…The middle layer (V2) governed vertical incision rates: fine-grained layers accelerated downward erosion, whereas coarse layers formed headcuts that restricted further deepening. …”
Get full text

Analysis of the molecular nature associated with microsatellite status in colon cancer identifies clinical implications for immunotherapy by Wei Wu, Qihan Fu, Lulu Liu, Yi Zheng, Hangyu Zhang, Peng Zhao, Weijia Fang, Xuanwen Bao, Shaobing Cheng, Xiaomeng Dai, Xudong Zhu, Zhou Tong, Fanglong Liu

“…A receiver operating characteristic curve was used to evaluate the accuracy rate of neural network, reaching 100%.Conclusion Our analysis unraveled the difference in the molecular nature and genomic variance in MSI and MSS colon cancer. …”
Get full text

Examining the Spatial Disequilibrium and Driving Factors of Population Aging and Elderly Service Resource Allocation in Rural Areas: A Case Study of Wenzhou City by Xiang Xiaoye, Lin Liyue, Xu Shiyu, Huang Tao

“…The results can be summarized as follows: 1) As Wenzhou enters a deeply aging society, the spatial distribution of the elderly population, elderly population density, population aging coefficient, elderly population support ratio, and comprehensive aging index are basically the same, showing a gradually increasing spatial pattern from the municipal district to the peripheral streets of the municipal district to the remote towns; 2) Elderly care service resources in Wenzhou present an asymmetrical and unbalanced north-south spatial distribution pattern with the municipal districts as " diversified supply in municipal streets, basic guarantee in developed coastal towns, and shortage of supply in inland mountainous towns "; 3) The streets of the municipal district have rich elderly care service resources, including Grade 3 general hospitals and comprehensive nursing homes, to provide diversified elderly care services for the elderly in the municipal district; there are many old-age care facilities such as hospitals, clinics, and nursing homes in Ruian, Yueqing City, and central towns such as Hongqiao and Aojiang, which provide basic old-age security for the elderly in and around the area. …”
Get full text

Overweight and Helicobacter pylori infection: a correlation in metabolic dysfunction-associated fatty liver disease by Xu Chen, Jiayue Fu, Jiayue Fu, Kejia Jin, Kejia Jin, Zixuan Yang, Zixuan Yang, Yidan Qian, Yidan Qian, Kehan Mei, Yihan Wang, Jialei Min, Yilin Du, Zaisheng Zhu, Zaisheng Zhu, Shengcun Li, Shengcun Li

“…Therefore, eradication of H. pylori infection may have positive implications for reducing the incidence rate of overweight MAFLD.…”
Get full text

Epidemiology and genetic characterization of porcine reproductive and respiratory syndrome virus in Fujian Province, China, from 2023 to 2024 by Long-Bin Kang, Long-Bin Kang, Qiu-Yong Chen, Qiu-Yong Chen, Bing He, Bing He, Ren-Jie Wu, Ren-Jie Wu, Jing-Li Qiu, Jing-Li Qiu, Ru-Jing Chen, Ru-Jing Chen, Xue-Min Wu, Xue-Min Wu, Long-Bai Wang, Long-Bai Wang, Lun-Jiang Zhou, Lun-Jiang Zhou

“…The results revealed that the overall prevalence rate of PRRSV was 16.79% (44/262), PRRSV-1 and PRRSV-2 genotypes were co-prevalent in Fujian. …”
Get full text

CONCOMITANT CARDIOVASCULAR DISEASES AND ANTIHYPERTENSIVE TREATMENT IN OUTPATIENT PRACTICE (BY THE RECVASA REGISTRY DATA) by M. M. Loukianov, S. A. Boytsov, S. S. Yakushin, S. Yu. Martsevich, A. N. Vorobyev, A. V. Zagrebelnyy, N. N. Nikulina, K. G. Pereverzeva, E. A. Pravkina, A. D. Deev, E. V. Kudryashov, E. N. Belova

“…The mean number of prescribed AHDs was 1.73. The mean incidence rate of target blood pressure achievement was 26.1%. …”
Get full text

Selenium + Vitamin E Supplementation in Anestrus Goats: A Strategy to Enhance Reproductive Outcomes Under a Semi-Arid Production System by Raquel Santos-Silva, Cesar A. Meza-Herrera, Brenda Castro-Roque, Guadalupe Calderón-Leyva, Cayetano Navarrete-Molina, Oscar Angel-García, Jessica M. Flores-Salas, Angeles De Santiago-Miramontes, Fernando Arellano-Rodriguez, Cesar A. Rosales-Nieto

“…The response variables included estrus induction (EI), ovulatory rate (OR), corpus luteum diameter (CLD), left and right ovary diameters (LOD and ROD), embryo implantation (EMBRYO), and pregnancy rates (PREG). …”
Get full text

Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bov... by Leonie Seemann, Susanne Kersten, Susanne Bühler, Fabian Billenkamp, Ulrich Meyer, Christian Visscher, Korinna Huber, Erika Most, Klaus Eder, Sven Dänicke, Jana Frahm

“…The same applied for PBMC mitochondrial functionality and metabolic activity as assessed by ex vivo approaches, whereas non-mitochondrial respiration rate was significantly affected by L-carnitine supplementation over time. …”
Get full text