Assessment of the Impacts of Different Carbon Sources and Sinks on Atmospheric CO₂ Concentrations Based on GEOS-Chem by Ge Qu, Jia Zhou, Yusheng Shi, Yongliang Yang, Mengqian Su, Wen Wu, Zhitao Zhou

“…The results show that global CO₂ concentration exhibits a spatial pattern with higher concentrations in the Northern Hemisphere and land areas, with East Asia, Southeast Asia, and eastern North America being high-concentration regions. …”
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Anticancer properties of copolymer nanoparticles loaded with Foeniculum vulgare derivatives in Hs578T and SUM159 cancer cell lines by Shima Bourang, Sodabeh Jahanbakhsh Godehkahriz, Mehran Noruzpour, Rasool Asghari Zakaria, Sergio Granados-Principal

“…Moreover, the drug release pattern illustrated a higher release rate from synthesized nanoparticles under acidic conditions (pH = 5). …”
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Widespread geographic distribution of filarioid nematodes in caribou (Rangifer tarandus sspp.) in Canada by Aparna Mariyam Thomas, Guilherme G. Verocai, John Soghigian, Fabien Mavrot, Naima Jutha, Jan Adamczewski, Tracy Davison, Gwen Duytschaever, Arthur Fernandes, Allicia Kelly, Matthew R. Kulpa, Eve Lamontagne, Lisa-Marie Leclerc, Sara McCarthy, Ashley McLaren, Amanda D. Melin, Susan J. Kutz

“…The Arctic is currently experiencing an unprecedented rate of climate change, including warming temperatures and altered patterns of precipitation. …”
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Discovery and molecular identification of a new orthophasmavirus in the Asian citrus psyllid (Diaphorina citri) by Song Zhang, Song Zhang, Jing Chen, Jing Chen, Luqin Liu, Luqin Liu, Zhipeng Xie, Zhipeng Xie, Jiamei Liang, Jiamei Liang, Fulin Yan, Fulin Yan, Yaqin Song, Xuefeng Wang, Xuefeng Wang, Changyong Zhou, Changyong Zhou, Mengji Cao, Mengji Cao, Jinxiang Liu, Jinxiang Liu

“…To investigate viral transmission patterns, progeny were obtained from mated infected ACP parents and used to feed on host plants. …”
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Species Composition, Phenotypic and Genotypic Resistance Levels in Major Malaria Vectors in Teso North and Teso South Subcounties in Busia County, Western Kenya by Edward K. Githinji, Lucy W. Irungu, Paul N. Ndegwa, Maxwell G. Machani, Richard O. Amito, Brigid J. Kemei, Paul N. Murima, Geoffrey M. Ombui, Antony K. Wanjoya, Charles M. Mbogo, Evan M. Mathenge

“…Indoor resting mosquitoes had 100% mortality rate after 24 h since exposure. Overall SS genotypic frequency in Teso North and Teso South subcounties was 79.4% against 13.7% homozygous LL genotype and 6.9% heterozygous LS genotype. …”
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COVID-19 vaccine evidence monitoring assisted by artificial Intelligence: An emergency system implemented by the Public Health Agency of Canada to capture and describe the trajecto... by Su Hyun Lim, Mona Hersi, Ramya Krishnan, Joshua Montroy, Bonnie Rook, Kelly Farrah, Yung-En Chung, Adrienne Stevens, Joseline Zafack, Eva Wong, Nicole Forbes, April Killikelly, Kelsey Young, Matthew Tunis

“…Analysis of COVID-19 vaccine research patterns supports projections of research volume, type, and rate that will help predict resourcing and information needs to plan future emergency vaccine guidance activities.…”
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Leveraging a disulfidptosis-based signature to characterize heterogeneity and optimize treatment in multiple myeloma by Bingxin Zhang, Dong Zheng, Shuxia Zhu, Xinyi Zhang, Quanqiang Wang, Zhili Lin, Ziwei Zheng, Shujuan Zhou, Zixing Chen, Sisi Zheng, Enqing Lan, Luning Cui, Hansen Ying, Yu Zhang, Xuanru Lin, Qiang Zhuang, Honglan Qian, Xudong Hu, Yan Zhuang, Qianying Zhang, Zhouxiang Jin, Songfu Jiang, Yongyong Ma, Yongyong Ma, Yongyong Ma

“…Multiple myeloma (MM) is the second most prevalent hematologic malignancy characterized by a high synthesis rate of disulfide bond-rich proteins and chronic oxidative stress. …”
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Genome-wide associations spanning 194 in-hospital drug dosage change phenotypes highlight diverse genetic backgrounds in concurrent drug therapy by Alexander Pil Henriksen, Cristina Leal Rodríguez, Hannah Currant, Ioannis Louloudis, Jorge Hernansanz Biel, Maria Herrero-Zazo, Ewan Birney, Thomas Folkmann Hansen, Gianluca Mazzoni, Amalie Dahl Haue, Henning Bundgaard, Christian Erikstrup, Khoa Manh Dinh, Liam Quinn, Mie Topholm Bruun, Henrik Hjalgrim, Erik Sørensen, Christina Mikkelsen, Michael Schwinn, Ole Birger Vestager Pedersen, Henrik Ullum, Sisse Rye Ostrowski, Karina Banasik, Søren Brunak

“…As populations get older and medicine consumption rises, the rate of concurrent drug use and polypharmacy among patients is increasing. …”
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Glycogen depletion in astrocytes induces sex-dimorphic remodeling of astrocytic and synaptic structures with concomitant anxiety-like behaviors and maternal care deficits by Xiaotong Shi, Yuanyuan Zhu, Zhaoyichun Zhang, Ningcan Ma, Danyi He, You Wu, Ziyi Dai, Xinyan Qin, Yingyi Chen, Youyi Zhao, Haopeng Zhang, Jing Huang, Hui Zhang, Ze Fan

“…Maternal care was analyzed through pup retrieval assays and nest-building behavior, while offspring development was tracked via survival rates and ultrasonic vocalizations. Expression of hormonal receptors was identified via qPCR and immunofluorescence staining. …”
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Estimation of long-term gridded cloud radiative kernel and radiative effects based on cloud fraction by X. Liu, T. He, Q. Wang, X. Xiao, Y. Ma, Y. Wang, S. Luo, L. Du, Z. Wu, Z. Wu

“…The GCF-CRKs exhibit similar signs and patterns and enhanced stability compared to existing kernels. …”
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Epidemiological characterization of chronic myeloid leukaemia patients at an oncologic centre: A retrospective observational study by Ana Maria Meireles, Rita Calisto, Maria José Bento, Pedro Martinho Gouveia, Susana Bizarro, Manuel Teixeira, Cláudia Moreira, Ana Espírito Santo, Mário Mariz

“…Background: The chronic myeloid leukaemia population, treatment patterns and responses in Portugal are unknown. The aim of this study is to describe these features in a Portuguese reference centre. …”
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Multi-omics analysis of Taiwanofungus gaoligongensis: effects of different cultivation methods on secondary metabolites by Tingwen He, Tingwen He, Tingwen He, Xiaolong Yuan, Liangjun Xiao, Tanggeran Hu, Yi Wang, Xiaolei Zhao, Xiaolei Zhao, Xiaolei Zhao, Lu Li, Lu Li, Chengbo Peng, Chengbo Peng, Chengbo Peng, Hongling Zhang, Hongling Zhang, Hongling Zhang, Yuan Zheng, Yuan Zheng, Yuan Zheng, Yuan Zheng

“…This study compared the metabolite profiles and gene expression patterns of the fruiting bodies of T. gaoligongensis with those of three types of cultivated mycelia. …”
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Clinicopathological Evaluation of Rhabdomyosarcoma with Emphasis on Myogenin Expression and FOXO1 Gene Fusion in Various Morphological Subtypes: A Cohort Study by Sindhu Ramamurthy, Ahwini Nargund, Geeta V Patil Okaly, Usha Amirtham, Arun Kumar, Ahok Kumar

“…Among the four histomorphological subtypes of RMS, distinguishing the dense pattern of Embryonal RMS (ERMS) from the solid pattern of Alveolar RMS (ARMS) solely based on morphology is challenging and necessitates ancillary techniques. …”
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Multi-source Data-driven Analysis of Deformation and Influencing Factors for Expansive Soil Canal Slopes by ZHANG Yuhan, HU Jiang, LI Xing

“…This approach facilitates a comprehensive analysis of deformation patterns at the slope surface and various subsurface depths, while elucidating the dominant controlling factors governing expansive soil canal slope behavior.Results and Discussions　The study focused on a deep excavated expansive soil canal section (Stake 8+886~12+921) of a major water diversion project, yielding the following key findings: 1) The analysis of 128 Sentinel-1A images from March 2017 to December 2021 revealed that the deformation data obtained through SBAS-InSAR method showed less than 3mm discrepancy with surface vertical displacement measurements at monitoring points (fourth-stage berm at 9+363 and third-stage berm at 11+400), with consistent deformation trends, confirming the reliability of SBAS-InSAR for canal slope deformation monitoring. 2) The study section exhibited LOS deformation rates ranging from -10 to 24 mm/a, demonstrating overall uplift characteristics, with positive LOS deformation showing annual increase. …”
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Clinical Features of Liver Injury Induced by Immune Checkpoint Inhibitors in Japanese Patients by Koji Imoto, Motoyuki Kohjima, Tomonobu Hioki, Tomoyuki Kurashige, Miho Kurokawa, Shigeki Tashiro, Hideo Suzuki, Akifumi Kuwano, Masatake Tanaka, Seiji Okada, Masaki Kato, Yoshihiro Ogawa

“…Immune checkpoint inhibitors (ICIs) have improved the survival rate of patients carrying various malignant neoplasms. …”
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Association of cancer and outcomes of patients hospitalized for COVID-19 between 2020 and 2023 [version 2; peer review: 1 approved, 2 approved with reservations, 1 not approved] by Robert F Terry, Rugiatu Z Kamara, Robert J Samuels, Donald S Grant, Sulaiman Lakoh, Mustapha Kabba, Innocent Nuwagira, Yusuf Sheku Tejan, Sia Morenike Tengbe, Ibrahim Franklyn Kamara, Shermarke Hassan, Abdulai Tejan Jalloh, Divya Nair, Laura Merson

“…Conclusions This study's findings underscore the heightened vulnerability of hospitalized COVID-19 patients with cancer, revealing a higher mortality rate, longer hospital stays, and an unstructured pattern of care that reflects the complexity of managing severely ill patients during a public health crisis like the COVID-19 pandemic.…”
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Habit-learning and decision-making circuits are susceptible to glycemic variability in type 2 diabetes: a longitudinal study by Carolina Moreno, Carolina Moreno, Carolina Moreno, Otília C. d’Almeida, Otília C. d’Almeida, Joana Crisóstomo, Nádia Canário, Leonor Gomes, Leonor Gomes, Leonor Gomes, Miguel Castelo-Branco, Miguel Castelo-Branco

“…Linear regression analysis showed that, for each increase of 1 mmol/L in MAGE value, the SPC of the temporal lobe decreases on average by 1.2% (higher atrophy rate).ConclusionThe relationship between longitudinal GM atrophy and GV has a regionally specific pattern, suggesting localized brain susceptibility to intra-daily glucose fluctuations. …”
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Short light/dark cycles favour photosynthetic efficiency and growth in grapevines by Mariana Gómez Tournier, Laurent Torregrosa, Jana Kändler, Angélique Christophe, Romain Boulord, Anna Medici, Anne Pellegrino

“…T3/3 in both genotypes maintained stable net photosynthetic rates (An) and high photosystem II efficiency (φPSII) during the light cycle, avoiding the 62 % drop observed under T12/12 after 3 h of exposure. …”
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Viral characterization of the reassortants between canine influenza H3N2 and human pandemic (2009) H1N1 and avian H9N2 viruses in canine ex vivo tracheal explants by Tonia T. Kam, Christine H. T. Bui, Hin-Wo Yeung, Peter C. H. Wong, Alex W. H. Chin, John M. Nicholls, Malik Peiris, Kenrie P. Y. Hui, Leo L. M. Poon, Michael C. W. Chan

“…Results Co-passaging H3N2-CIV with human/avian influenza A viruses in canine tracheal explants resulted in a high rate of reassortment. Plaque-purified reassortants were all viable and able to propagate in mammalian alveolar epithelial cells. …”
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Eradication of Helicobacter pylori for prevention of aspirin-associated peptic ulcer bleeding in adults over 65 years: the HEAT RCT by CJ Hawkey, Anthony J Avery, Carol AC Coupland, Colin J Crooks, Jennifer S Dumbleton, FD Richard Hobbs, Denise Kendrick, Michael Moore, Clive Morris, Gregory Rubin, Murray Smith, Diane Stevenson

“…Limitations and future work Studying subjects already established on aspirin probably contributed to the low event rate. A future study should investigate subjects starting on aspirin when the event rate is higher. …”
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