Impact of post-transplant cyclophosphamide with bendamustine on immune reconstitution in young patients undergoing T-cell replete haploidentical bone marrow transplantation: result... by Forrest L. Baker, Forrest L. Baker, Forrest L. Baker, Jessica Stokes, Megan J. Cracchiolo, Dan Davini, Richard J. Simpson, Richard J. Simpson, Richard J. Simpson, Richard J. Simpson, Emmanuel Katsanis, Emmanuel Katsanis, Emmanuel Katsanis, Emmanuel Katsanis

“…Multi-parameter flow cytometry and TCR β sequencing of genomic DNA was performed on isolated PBMCs on PT days +30, +60, +100, +180, and +365.ResultsOverall, the PT-CY/BEN (n=14) regimen was associated with earlier neutrophil and platelet engraftment, reduced transfusion requirements, and comparable clinical outcomes to PT-CY (n=10), including survival and relapse rates. PT-CY/BEN patients exhibited distinct immune reconstitution patterns, characterized by earlier CD4+ T-cell recovery, impaired CD8+ T-cell engraftment, and reduced NK-cell counts. …”
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Global psychiatrists' opinions about hikikomori from biopsychosocial perspectives: International case vignette survey by Marcus P. J. Tan, Kohei Hayakawa, Yukako Nakagami, Victor Pereira‐Sanchez, Seon Cheol Park, Yong Chon Park, Seok Woo Moon, Tae Young Choi, Yu‐Tao Xiang, Kang Sim, Toru Horinouchi, Ajit Avasthi, Sandeep Grover, Roy Abraham Kallivayalil, Yugesh Rai, Mohammadreza Shalbafan, Pavita Chongsuksiri, Pichet Udomratn, Samudra T. Kathriarachchi, Afzal Javed, Mian‐Yoon Chong, Tan Chay‐Hoon, Toshiya Inada, Toshiya Murai, Tomohiro Nakao, Shigenobu Kanba, Shih‐Ku Lin, Norman Sartorius, Naotaka Shinfuku, Takahiro A. Kato

“…Most respondents felt the case could be treated by an outpatient visit, while others preferred hospitalization. Psychotherapy was rated highly as an intervention; Iran, South Korea, and “others” also rated pharmacotherapy highly. …”
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Gesture recognition for hearing impaired people using an ensemble of deep learning models with improving beluga whale optimization-based hyperparameter tuning by Mohammed Assiri, Mahmoud M. Selim

“…For the feature extraction process, the squeeze-and-excitation capsule network (SE-CapsNet) effectively captures spatial hierarchies and complex relationships within gesture patterns. In addition, an ensemble of classification processes, such as bidirectional gated recurrent unit (BiGRU), Variational Autoencoder (VAE), and bidirectional long short-term memory (BiLSTM) technique, is employed. …”
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An Overview of Deep Learning Applications in Groundwater Level Modeling: Bridging the Gap between Academic Research and Industry Applications by Ahmed Shakir Ali Ali, Farhad Jazaei, Peyman Babakhani, Muhammad Masood Ashiq, Alireza Bakhshaee, Brian Waldron

“…Later, this article delves specifically into the latest advancements in DL for modeling GWL, including recurrent neural network (RNN), long short-term memory (LSTM), and gated recurrent unit (GRU), and discusses their technical promising performance and advantages. …”
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Mediodorsal thalamic nucleus mediates resistance to ethanol through Cav3.1 T-type Ca2+ regulation of neural activity by Charles-francois V Latchoumane, Joon-Hyuk Lee, Seong-Wook Kim, Jinhyun Kim, Hee-Sup Shin

“…Thalamocortical activity is known to orchestrate sensory gating and consciousness switching. The precise thalamic regions involved, or the firing patterns related to the unconsciousness, remain unclear. …”
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Smart Grid Intrusion Detection for IEC 60870-5-104 With Feature Optimization, Privacy Protection, and Honeypot-Firewall Integration by Pedamallu Sai Mrudula, Rayappa David Amar Raj, Archana Pallakonda, Yanamala Rama Muni Reddy, K. Krishna Prakasha, V. Anandkumar

“…The experimental results demonstrate the framework’s operational capability and effectiveness for SCADA network security, achieving 99.29% accuracy, 94.8% recall and 4.1% false positive rates.…”
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DiffuseGaitNet: Improving Parkinson’s Disease Gait Severity Assessment With a Diffusion Model Framework by Arshak Rezvani, Nasrin Ravansalar, Mohammad Ali Akhaee, Andrew J. Greenshaw, Russell Greiner, Maryam S. Mirian, Muhammad Yousefnezhad, Martin J. McKeown

“…Assessing the severity of gait impairment in Parkinson’s disease (PD) using the Movement Disorder Society’s Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) is typically performed by clinical experts, but this process is time-consuming, subjective, and costly. …”
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Whole-Genome Sequence-Based Diversity of <i>Mycobacterium tuberculosis</i> Strains Isolated from a Central Western Region of Mexico by Andrea Monserrat Negrete-Paz, Gerardo Vázquez-Marrufo, Adrián Rodríguez-Carlos, Bruno Rivas-Santiago, Ma. Soledad Vázquez-Garcidueñas

“…Tuberculosis remains a significant health issue in Mexico, which has one of the highest incidence rates in the Americas. This study aimed to analyze the circulating sublineages, spoligotypes, drug resistance, and transmission patterns of <i>Mycobacterium tuberculosis</i> in Mexico’s Central Western region using whole-genome sequencing. …”
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Multimorbidity frailty index and clinical outcomes among 42,989 older heart failure patients directly discharged from emergency departments: A nationwide retrospective cohort study by Wan-Ju Liao, Hsi-Yu Lai, Liang-Yi Lin, Cheng-Hsueh Wu, Fei-Yuan Hsiao, Liang-Kung Chen

“…Readmission rates showed similar patterns. The severely frail group had higher risks of mortality (aHR 1.44, 95 % CI 1.33–1.55), all-cause readmissions (sHR 1.69, 95 % CI 1.62–1.76), and HF-related readmissions (sHR 1.59, 95 % CI 1.48–1.71). …”
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Farm households’ livelihood adaptive capacity under multiple pressures of small watershed management by Yaru Sun, Yilin Gan, Jing Luo, Tingting Han, Hafo Wang, Ruirui Yang, Lingling Tian

“…However, the FHLAC remains predominantly low to moderate in the small watershed. The contribution rates of livelihood pressure, livelihood capital, and willingness to adapt to FHLAC are 22.24 %, 28.69 %, and 49.07 %, respectively. …”
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Geospatial analysis of cholera outbreak in Lusaka, Zambia, between 2023 and 2024 by William Ngosa, Tadatsugu Imamura, Nyuma Mbewe, Joseph Seriki, Oscar Nzila, Fred Mfune, Godfrey Zulu, Chomba Mulando, Tizha Chiluba, Luo Miyanda, Agness Phiri, Lucy Sichone, Galion Mwape, Kapambwe Mulenga, Charles Chileshe, Nawa Mabuku, Dabwiso Banda, Fangyu Yan, Taro Kamigaki, Roma Chilengi, Nyambe Sinyange

“…Results Over the study period, 4,591 suspected cholera cases with geocoordinate data were identified, with incidence rates varying across the constituencies. Median cholera incidence (IQR) was 0.55 (0.27–1.44) in Lusaka, with higher incidence rates observed in unplanned residential areas. …”
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Evaluation of the Effects of Anesthetics and Surgery on Sleep Quality in Patients Undergoing Posterior Spinal Instrumentation Surgery: A Prospective Randomised Clinical Trial by Selcan Akesen, Gökay Eken, Yücel Bilgin, Saltuk Buğra Güler, Elifgül Ulutaş

“…Introduction: The aim of the study is to evaluate the impact of the anesthesia methods and surgical procedure on the sleep patterns and sleep quality of patients undergoing posterior spinal instrumentation, using the Pittsburgh Insomnia Rating Scale-20 (PIRS-20). …”
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AI-DBS study: protocol for a longitudinal prospective observational cohort study of patients with Parkinson’s disease for the development of neuronal fingerprints using artificial... by Martijn Beudel, Rick Schuurman, Rob M A de Bie, Deborah Hubers, Mariëlle J Stam, Martijn G J de Neeling, Bart J Keulen, Arthur W G Buijink, Bernadette C M van Wijk

“…The objective of the AI-DBS study is to identify patient-specific patterns of neuronal activity that are associated with the severity of motor symptoms of PD. …”
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Sex determination and stature estimation using logistic and linear regression models: A population-specific study of tibia and Fibula in Northeastern Thais by Suthat Duangchit, Chanasorn Poodendaen, Phetcharat Phetnui, Pornpimol Tasu, Worrawit Boonthai, Nareelak Tangsrisakda, Sitthichai Iamsaard

“…Results: For sex determination, the results showed that univariate logistic regression models achieved the accuracy rates up to 87.50 %, with maximum proximal epiphyseal breadth of the tibia demonstrating highest discriminatory power. …”
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Molecular and genomic investigation of an urban outbreak of dengue virus serotype 2 in Angola, 2017-2019. by Zoraima Neto, Pedro A Martinez, Sarah C Hill, Domingos Jandondo, Julien Thézé, Marinela Mirandela, Renato Santana Aguiar, Joilson Xavier, Cruz Dos Santos Sebastião, Ana Luísa Micolo Cândido, Filipa Vaz, Gisel Reyes Castro, Joana Paula Paixão, Nicholas J Loman, Philippe Lemey, Oliver G Pybus, Jocelyne Vasconcelos, Nuno Rodrigues Faria, Joana de Morais

“…<h4>Background</h4>The transmission patterns and genetic diversity of dengue virus (DENV) circulating in Africa remain poorly understood. …”
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Dynamic parking space allocation at urban scale: Problem formulation and resolution by Hanae Errousso, Jihane El Ouadi, El Arbi Abdellaoui Alaoui, Siham Benhadou

“…To do this, we consider both solicitation rates in these areas and coverage ratios of received parking demands. …”
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The characteristics of new-onset myasthenia gravis after COVID-19 outbreak: a cross-sectional study by Yanzhen Huang, Yu Wu, Shaodan Zhou, Xianting Que, Ailing Jiang, Danli Shi, Ting Lu, Yanlan Chen, Ziqun Lin, Chao Liu, Yishuang Wen, Shuyi Zhang, Wen Huang

“…After COVID-19 outbreak, there was an increase in new-onset MG patients, with more cases occurring within the first three months. The rates of pulmonary inflammation (40.28%), COVID-19 vaccination (88.14%), and treatment with tacrolimus (15.98%) and MG duration (15 weeks, IQR: 5.75, 32) were higher, while rates of thymectomy (13.92%), baseline MG-ADL (3, IQR: 3, 6), and QMGS (7, IQR: 5,8) were lower compared to new-onset MG patients before COVID-19 outbreak. …”
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Solar dryers: A review of mechanism, methods and critical analysis of transport models applicable in solar drying of product by Onyinyechi Nnamchi, Cyprian Tom, Godwin Akpan, Murphy Umunna, David Ubong, Mathew Ibeh, Adindu Linus–Chibuezeh, Leonard Akuwueke, Stephen Nnamchi, Augustine Ben, Macmanus Ndukwu

“…Solar drying has been demonstrated to be a sustainable and eco-friendly drying process for drying and preserving agricultural products, offering advantages over traditional methods that include faster drying rates, improved product quality, and reduced energy costs. …”
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Assessing Natural Variation as a Baseline for Biodiversity Monitoring: The Case of an East Mediterranean Canyon by Meir Finkel, Ariel Leib Leonid Friedman, Hagar Leschner, Ben Cohen, Hoshen Inbar, Shai Gelbert, Agam Rozen, Eitan Barak, Ido Livne, Ittai Renan, Gilad Ben-Zvi, Orr Comay

“…Despite substantial species turnover rates between periods in all the taxa, almost no change was found regarding the biogeographical origins of plant and beetle species composition. …”
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Deep learning enhanced road traffic analysis: Scalable vehicle detection and velocity estimation using PlanetScope imagery by Maciej Adamiak, Yulia Grinblat, Julian Psotta, Nir Fulman, Himshikhar Mazumdar, Shiyu Tang, Alexander Zipf

“…Satellite-based approaches provide broad spatial coverage, but face challenges, including high costs, low frame rates, and difficulty detecting small vehicles in medium-resolution imagery. …”
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