Nonlinear association between AST/ALT ratio and 28-day all-cause mortality following ICU admission in critically ill cirrhotic patients: a retrospective cohort study by Zhigang Xu, Baohong Xu

“…Results The study involved 2,090 critically ill liver cirrhosis patients, averaging 59.1 years old, with 65% male and a 28-day post-ICU admission mortality rate of 29%. The AST/ALT ratio was linked to mortality risk (adjusted odds ratio (OR) 1.1, 95% confidence interval (CI) 1.0–1.2; p = 0.015), showing a nonlinear pattern with a critical point at 3.6. …”
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RETRACTED ARTICLE: Interleukin-27 ameliorates coxsackievirus-B3-induced viral myocarditis by inhibiting Th17 cells by Hengshan Zhu, Chuang Lou, Ping Liu

“…However, the expression pattern and functional role of IL-27 in viral myocarditis (VMC) has not been investigated. …”
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Advances in application of ultrasound in diagnosis of diabetic nephropathy by GUO Juan, YANG Zhifang, JI Ri

“…As the global incidence rate of diabetes continues to rise, the clinical diagnosis and treatment of DN have become increasingly critical. …”
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Echocardiographic assessment of left atrial structural and functional changes after catheter ablation in paroxysmal atrial fibrillation with preserved ejection fraction by Qi Zhang, Nan Nan Liu, Jing Shu Sun, Zu Lu Wang, Ming Liang, Gui Shen Li, Mei Yi Wang

“…After catheter ablation, LA reverse remodeling exhibits a pattern of “functional recovery preceding structural recovery”. …”
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Sexually transmitted infections among patients attending the General Practice Clinic, Wesley Guild Hospital, Ilesa, Nigeria by S.S. Olakolu, E.A. Abioye Kuteyi, O.O. Oyegbade

“…The aim of this study was to describe the pattern of STIs among patients attending a Nigerian general practice (GP) clinic. …”
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Hyper-induction of IL-6 after TLR1/2 stimulation in calves with bovine respiratory disease. by Cian Reid, John Donlon, Aude Remot, Emer Kennedy, Giovanna De Matteis, Cliona O'Farrelly, Conor McAloon, Kieran G Meade

“…TLR1/2 stimulation with Pam3CSK4 showed a decreased pattern of expression in IL-1 and inflammasome related genes in addition to chemokine genes in calves with BRD. …”
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Experimental Investigation on Energy Dissipation in Diversion Tunnel at the Head of Canal by ZHONG Kun, YAN Fu-gen, GUO Jian-hua, YI Shun, LI Min-kang

“…Then, based on the hydraulic model test results under different conditions, the downstream flow pressure characteristics, cavitation characteristics of the weir surface behind the operating gate, pressure characteristics of the gradually expanding stilling basin floor and sidewalls, flow connection patterns, and energy dissipation performance were obtained. …”
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Analysis of HBV infection characteristics and OBI prevalence in pregnant women: a focus on HBcAb + alone or in combination with HBeAb + subgroups in Northwest China by Yun Xie, Ru Kang, Xiaoyue Cheng, Dan Li, Qi Wang, Jiao Li, Xuan Guo, Wenhui Gao, Xin He, Liutong Jiang, Gaili Meng

“…Abstract Background Hepatitis B virus (HBV) infection is a major global health concern. Serological patterns such as “HBeAb + and HBcAb+” or “HBcAb + only” are typically markers, which may represent either resolved infection or potential occult HBV infection (OBI) with risk of vertical transmission. …”
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Trends in United States mortality among patients with atrial fibrillation/flutter related heart failure (1999–2024): disparities by gender, race/ethnicity and region by Suraksha Rani, Laksh Kumar, Sheikh Muhammad Ebtehaj Ali, Saad Ashraf, Sunaina Bhimani, Sumet Kumar, Adarsh Raja, Abdullah BS, Biruk Demisse Ayalew, Mohammad Hamza Bin Abdul Malik

“…The age-adjusted mortality rate (AAMR) rose significantly from 8.2 to 24.3 per 100,000 population. …”
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Geographic distribution and trends of small-area burn claims in Japan: An analysis using NDB open data from 2014 to 2021 by Takeshi Utsunomiya, Takahiro Ueda

“…Introduction Burns are a major global health issue, causing approximately 180,000 deaths annually and leading to high morbidity rates. The Japan Trauma Data Bank Report 2022 recorded 1749 burn cases, with a mortality rate of 17.6%. …”
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Impact of Sex and Age on Trends of Mortality From Infective Endocarditis in High-Income Countries by Makoto Hibino, MD, MPH, PhD, Hiroki A. Ueyama, MD, Raj Verma, Hwee Teoh, PhD, Bobby Yanagawa, MD, PhD, Deepak L. Bhatt, MD, MPH, MBA, Subodh Verma, MD, PhD

“…Conclusions: Mortality rate from infective endocarditis is increasing in most countries, with varying patterns and degrees of changes observed in relation to sex and age. …”
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Temporal Trends in Acute Kidney Injury in Hospitalizations From 2009-2018 in Alberta: A Retrospective Population-Based Cohort Study by Anita Dahiya, Natasha Wiebe, Tyrone G. Harrison, Matthew T. James, Neesh Pannu

“…Furthermore, there was an overall increase in rates of AKI in patients aged younger than 60 and a decrease in the most elderly of patients in both the crude and adjusted data, suggesting potential changes in practice patterns and patient characteristics. …”
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Long-term growth and risk factors for crankshaft phenomenon following posterior hemivertebra resection with mono-segment fusion in congenital early-onset scoliosis by Zhiming Peng, Yiwei Zhao, You Du, Haoran Zhang, Shengru Wang, Jianguo Zhang

“…While posterior hemivertebra resection (HVR) with mono-segment fusion has demonstrated efficacy in correcting spinal deformities, the long-term growth patterns of vertebral structures and risk factors for the crankshaft phenomenon remain poorly characterized. …”
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The effect of photodynamic therapy on the wound process dynamics in patients with purulent hand diseases by J. L. Chepurnaya, G. G. Melkonyan, N. T. Gul’muradova, A. A. Sorokin

“…Photodynamic therapy was performed on the second postsurgical day by a laser apparatus “Atkus-2” (wave length 661 nm) with a gel form of the chlorinseries photosensitizer photoditazin in the form of an application at the rate of 1 g ml per 3–5 cm2 of the wound surface. …”
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Probabilistic seasonal dengue forecasting in Vietnam: A modelling study using superensembles. by Felipe J Colón-González, Leonardo Soares Bastos, Barbara Hofmann, Alison Hopkin, Quillon Harpham, Tom Crocker, Rosanna Amato, Iacopo Ferrario, Francesca Moschini, Samuel James, Sajni Malde, Eleanor Ainscoe, Vu Sinh Nam, Dang Quang Tan, Nguyen Duc Khoa, Mark Harrison, Gina Tsarouchi, Darren Lumbroso, Oliver J Brady, Rachel Lowe

“…As a climate-sensitive disease, environmental conditions and past patterns of dengue can be used to make predictions about future outbreak risk. …”
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Influence of precipitation and runoff on human-induced land subsidence in the Yellow River Delta by Yaoshen Fan, Guangzhou Wang, Shentang Dou, Chao Jiang, Hongyu Ji, Shenliang Chen, Xiaokang Du, Shoubing Yu, Yan Wu, Shaohua Zhang

“…The study reveals pronounced seasonal variations in land subsidence across the YRD, with subsidence rates in summer being substantially lower than those in spring, autumn, and winter. …”
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Endoscopic management of large laterally spreading colorectal tumors (LSTs): a comparative study of techniques and outcomes by V. S. Tkachov, O. M. Kiosov, A. V. Klymenko

“…To compare EMR, pEMR, ESD, and hybrid ESD with respect to complication rates (bleeding, perforation), recurrence, and influencing factors. …”
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An epigenome-wide association study in the case-control study to explore early development identifies differential DNA methylation near ZFP57 as associated with autistic traits by Ellen M. Howerton, Valerie Morrill, Rose Schrott, Jason Daniels, Ashley Y. Song, Kelly Benke, Heather Volk, Homayoon Farzadegan, Aimee Anido Alexander, Amanda L. Tapia, Gabriel S. Dichter, Lisa A. Croen, Lisa Wiggins, Genevieve Wojcik, M. Daniele Fallin, Christine Ladd-Acosta

“…We sought to identify DNA methylation patterns in child blood associated with Social Responsiveness Scale score, Second Edition (SRS). …”
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Metal–organic nanostructures based on sono/chemo-nanodynamic synergy of TixOy/Ru reaction units: for ultrasound-induced dynamic cancer therapy by Tao Jiang, Zixiang Tang, Shumiao Tian, Haitian Tang, Zhekun Jia, Fangjian Li, Chenyue Qiu, Lin Deng, Lang Ke, Pan He, Gang Liu, Chengchao Chu, Yongfu Xiong

“…Remarkably, ultrasound irradiation induced substantial oxidative stress and immunogenic cell death, promoting the release of damage-associated molecular patterns (DAMPs), which elevated the maturation rate of tumor-infiltrating dendritic cells (DCs) and significantly increased the proportion of CD8⁺ T cells. …”
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Deep learning and genomic best linear unbiased prediction integration: An approach to identify potential nonlinear genetic relationships between traits by F. Shokor, P. Croiseau, H. Gangloff, R. Saintilan, T. Tribout, T. Mary-Huard, B.C.D. Cuyabano

“…Deep learning (DL) offers a promising alternative for capturing nonlinear genetic relationships due to its ability to identify complex patterns without prior assumptions about the data structure. …”
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