Toxicokinetics, tissue distribution, and toxic potency of PFOS alternative OBS in adult zebrafish (Danio rerio) based on flow-through exposure system by Yilong Zou, Yu Zhou, Xianglian Wang, Guiqing Gao, Gang Chen, Zhanmeng Liu, Mi Deng, Xueping Huang, Yongming Wu

“…Our findings indicate that OBS accumulated rapidly in zebrafish, with log kinetic bioconcentration factor (logBCFk) values ranging from 2.48 to 2.70 and slow elimination rates (ke = 0.0490–0.0643 d−1). The blood, liver, and muscle were responsible for over 50 % of the total body burden of OBS, with tissue concentrations decreasing in the following order: blood > liver > intestine > gills > gonad > brain > muscle, suggesting a tissue-specific accumulation pattern. …”
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The system of atmosphere, land, ice and ocean in the region near the 79N Glacier in northeast Greenland: synthesis and key findings from the Greenland Ice Sheet–Ocean Interaction (... by T. Kanzow, T. Kanzow, A. Humbert, A. Humbert, T. Mölg, M. Scheinert, M. Braun, H. Burchard, F. Doglioni, P. Hochreuther, M. Horwath, O. Huhn, M. Kappelsberger, J. Kusche, E. Loebel, K. Lutz, B. Marzeion, B. Marzeion, R. McPherson, M. Mohammadi-Aragh, M. Mohammadi-Aragh, M. Möller, M. Möller, C. Pickler, M. Reinert, M. Rhein, M. Rhein, M. Rückamp, M. Rückamp, J. Schaffer, J. Schaffer, M. Shafeeque, M. Shafeeque, S. Stolzenberger, R. Timmermann, J. Turton, J. Turton, C. Wekerle, O. Zeising

“…Observations and models employed in this study are consistent in terms of melt rates occurring below the floating ice tongue. Our results suggest that the multidecadal warming of Atlantic Intermediate Water flowing into the cavity below the ice tongue – supplied by the recirculating branch of the West Spitsbergen Current in Fram Strait – is the main driver of the recent major increase in basal melt rates. …”
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Relevance of Cellular Homeostasis-Related Gene Expression Signatures in Distinct Molecular Subtypes of Breast Cancer by Sharda P. Singh, Chathurika S. Dhanasekara, Michael W. Melkus, Chhanda Bose, Sonia Y. Khan, Flavia Sardela de Miranda, Maria F. Mahecha, Prrishti J. Gukhool, Sahil S. Tonk, Se-Ran Jun, Sahra Uygun, Rakhshanda Layeequr Rahman

“…Demographic factors such as age, race/ethnicity, menopausal status, and body mass index have been correlated with variations in incidence, mortality, and survival rates. Over the past decade, comprehensive genomic profiling has been widely used to identify molecular biomarkers and signatures to develop novel therapeutic strategies for patients. …”
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Multi-omics derivation of a core gene signature for predicting therapeutic response and characterizing immune dysregulation in inflammatory bowel disease by Mingming Wang, Liping Liang, Zibo Tang, Jimin Han, Lele Wu, Le Liu, Le Liu, Ye Chen, Ye Chen

“…Nomogram-based risk stratification effectively predicted biologic treatment responses across multiple therapeutic classes using four independent treatment datasets (GSE16879, GSE92415, GSE73661, GSE206285): low-risk patients demonstrated superior response rates to golimumab (63.3%), infliximab (54.8%), and vedolizumab (29% vs. 15% in high-risk group). …”
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Negative Regulation of <i>GmNAC35</i> by miR164 Enhances Drought Tolerance in Soybean by Wentao Hu, Man Zhang, Jie Lu, Miaomiao Zhang, Reqing He, Youlin Zhu, Dong Wang, Liyun Jiang

“…Conversely, <i>GmNAC35</i> showed an inverse pattern, indicating negative regulation by miR164. …”
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An integrated high-resolution bathymetric model for the Danube Delta system by L. Alaerts, L. Alaerts, J. Lambrechts, N. R. Randresihaja, N. R. Randresihaja, L. Vandenbulcke, O. Gourgue, E. Hanert, E. Hanert, M. Grégoire

“…These error rates are comparable to those observed in bathymetry interpolation in rivers with similar source datasets. …”
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Biomechanical evaluation of novel construct for stabilizing subcapital femoral neck fractures: a synthetic bone model by Anjan R. Shah, Miguel A. Diaz, Douglas L. Cerynik, Blake Schultz

“…Abstract Background High complication rates continue to be reported for femoral neck fractures, where moderate to severe shortening has been associated with pain and inferior functional outcomes. …”
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Preoperative Bowel Preparation in Minimally Invasive and Vaginal Gynecologic Surgery by Michail Diakosavvas, Nikolaos Thomakos, Alexandros Psarris, Zacharias Fasoulakis, Marianna Theodora, Dimitrios Haidopoulos, Alexandros Rodolakis

“…Taking into consideration the fact that in most gynecologic cases there is minimal probability of bowel intraluminal entry and, thus, low surgical site infection rates, most scientific societies have issued guidelines against the use of any bowel preparation regimen before laparoscopic or vaginal surgery. …”
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Copper and Temperature Interactions Induce Differential Physiological and Metal Exclusion Responses in the Model Brown Macroalga <i>Ectocarpus</i> by Alex Santillán-Sarmiento, Paula S. M. Celis-Plá, A. John Moody, Claudio A. Saez, Murray T. Brown

“…In this study, we exposed the model brown seaweed <i>Ectocarpus</i> to different Cu concentrations (0, 0.8, 1.6, and 3.2 μM) at two different temperatures (15 and 25 °C). Relative growth rates decreased at 25 °C for the two highest Cu concentrations after 8 days of exposure, but a contrasting pattern was observed in the photosynthetic maximum quantum yield (<i>F_v</i>/<i>F_m</i>) and photosynthetic efficiency (<i>α</i>), where reductions were observed at 15 °C for the same Cu concentrations. …”
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Systemic Immunomodulatory Therapy in Uveitis Related to Beh&amp;ccedil;et&amp;rsquo;s Disease: A 10-year Profile by Almeida M, Ferreira AM, Araújo JR, Figueira L

“…The median treatment duration was 63.5 months, significantly reducing relapse rates from 2 ± 2.0 to 1 ± 1.2 per year (p &lt; 0.001). …”
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Antimicrobial Resistance Profile and Biofilm Formation of <i>Listeria monocytogenes</i> Isolated from Meat by Joana Paiva, Vanessa Silva, Patrícia Poeta, Cristina Saraiva

“…Introduction: <i>Listeria monocytogenes</i> is the causative agent of listeriosis, a serious infectious disease with one of the highest case fatality rates among foodborne diseases affecting humans. …”
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Treatment for Paget’s disease: surgical approaches by E. Yu. Fetisova, A. D. Zikiryakhodzhaev, N. N. Volchenko

“…Breast cancer (BC) ranks first in the pattern of female malignancies (20.7 %) and remains the top cancer among women. …”
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Socioeconomic inequalities in non-communicable diseases prevalence in India: disparities between self-reported diagnoses and standardized measures. by Sukumar Vellakkal, Sukumar Vellakkal, S V Subramanian, Christopher Millett, Sanjay Basu, David Stuckler, Shah Ebrahim

“…<h4>Methods</h4>We calculated age-adjusted prevalence rates of common NCDs from the Study on Global Ageing and Adult Health, a nationally representative cross-sectional survey. …”
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Ten-year outcomes of IMRT with chemotherapy versus IMRT alone for stage II–IVa nasopharyngeal carcinoma: a retrospective study by Xiao-li Wang, Da-qing Sun, Hui Yang, Yang Li, Xiu-feng Li, Xiao-long Chang, Xiang-di Meng, Ya-nan Zhang, Yun-xiang Zhang, Fu-rong Hao, Jian-wen Li

“…The 10-year OS, PFS, LRFS, and DMFS rates were 66.6%, 75.3%, 91.9%, and 81.2%, respectively. …”
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Impact of Calcium and Potassium Currents on Spiral Wave Dynamics in the LR1 Model by Xiaoping Yuan, Qianqian Zheng

“…We demonstrate that reducing gate variables accelerates wave propagation, thins spiral arms, and shortens action potential duration, ultimately inducing dynamic instability. …”
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Clinical, epidemiological, and virological features of Mpox in Beijing, China – May 31–June 21, 2023 by Xiangfeng Dou, Fu Li, Zhenyong Ren, Daitao Zhang, Jia Li, Dan Li, Yulan Sun, Haoyuan Jin, Renqing Li, Weihong Li, Xin Zhang, Yang Yang, Lei Jia, Yu Han, Wai Li, Yang Pan, Wenjie Tan, Peng Yang, Quanyi Wang

“…There were high oropharyngeal swab (75.8%) and blood (84.6%) positivity rates. All MPXV strains belonged to the B.1.3 branch of the West African lineage. …”
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A low-cost mitigation system for ammonia removal from broiler house exhaust air by Jingjing Luo, Jinsheng Rong, Shizhen Zhou, Haoliang Wang, Miao Li, Xiliang Yan, Yingbao Wu, Yan Wang

“…The results of the environmental simulation chamber show that 80 ppm hypochlorous acid and 70 ppm chlorine dioxide are cost-effective, achieving high ammonia (NH₃) removal rates. Field validation in a broiler house demonstrated that using 80 ppm hypochlorous acid with the ARBS achieved NH₃ and dust removal efficiencies of 82 % and 77 %, respectively. …”
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Gut Microbiota and Lipid Metabolism in Bullfrog Tadpoles: A Comparative Study Across Nutritional Stages by Zhilong Wang, Pengxiang Liu, Jun Xie, Huirong Yang, Guangjun Wang, Kai Zhang, Rui Shu, Zhifei Li, Jingjing Tian, Hongyan Li, Wenping Xie, Wangbao Gong, Yun Xia

“…These insights provide a theoretical foundation for nutritional interventions aimed at enhancing tadpole growth and survival rates.…”
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Short light/dark cycles favour photosynthetic efficiency and growth in grapevines by Mariana Gómez Tournier, Laurent Torregrosa, Jana Kändler, Angélique Christophe, Romain Boulord, Anna Medici, Anne Pellegrino

“…T3/3 in both genotypes maintained stable net photosynthetic rates (An) and high photosystem II efficiency (φPSII) during the light cycle, avoiding the 62 % drop observed under T12/12 after 3 h of exposure. …”
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Bridging micro and macroevolution: insights from chromosomal dynamics in plants by Carmen Benítez-Benítez, Ashwini V. Mohan, Rogelio Sánchez-Villegas, Inés Gómez-Ramos, Ana Valdés-Florido, Kay Lucek, Marek Slovák, Marek Slovák, Filip Kolář, Filip Kolář, Ilia J. Leitch, Modesto Luceño, Isabel Larridon, Angelino Carta, Angelino Carta, Joan Cuscó-Borràs, Enrique Maguilla, Alegría Montero-Ramírez, Patrick G. Meirmans, Alison Dawn Scott, Santiago Martín-Bravo, Marcial Escudero

“…At the macroevolutionary level, we investigated the association between karyotype diversity and diversification rates using evidence from comparative genomics, chromosomal evolution modelling across phylogenies, and the association with several traits across different angiosperm lineages. …”
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