Toll-like receptor 4 promotes proliferation and apoptosis resistance in human papillomavirus–related cervical cancer cells through the Toll-like receptor 4/nuclear factor-κB pathwa... by Ninghong Jiang, Feng Xie, Qisang Guo, Ming-Qing Li, Jingjing Xiao, Long Sui

“…Proliferation of HeLa and Caski cells was promoted in lipopolysaccharide-stimulated groups but suppressed in short hairpin RNA–transfected groups. Apoptosis rates were lower in lipopolysaccharide-stimulated groups relative to short hairpin RNA–transfected groups. …”
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Global, regional, and national burden of sudden infant death syndrome and the impact of COVID-19: a trend and health inequality analysis based on the global burden of disease study... by Xinkuo Zheng, Meishen Liu, Xingwei Zhao, Xiuqi Xu, Wei Tao, Ling Wu, Weijia Sun, Yuhang Dong, Yalin Xi

“…Age-standardized DALY rates (ASDR; per 100,000 population) with 95% uncertainty intervals (UIs) were calculated for 204 countries and territories, stratified by age, location, and socio-demographic index (SDI).ResultsIn 2021, the ASDR of SIDS accounted for 44.16 (95% UI: 25.70–59.26) per 100,000 population globally, which was a 58.97% decrease from 1990. …”
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Spectrum and epidemiology of rare diseases in a Chinese natural population of 14.31 million residents, 2012–2023 by Ming-Jia Li, Qi Li, Miao-Miao Zhao, Hanna Kim, Ruo-Qi Feng, Mo-Ning Guo, Jian-Peng heng, Jin-Kui Yang, Chang Liu

“…Age-standardized incidence rates (ASIR) were calculated per 100,000 person-years with 95% confidence intervals. …”
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Six decades of global crop yield increase and cropland expansion from 1960 to 2020 by Karina Winkler, Richard Fuchs, Mark Rounsevell, Martin Herold

“…Brazil, Indonesia, Thailand, Colombia, and Malaysia), had both the highest crop yield increases and cropland expansion rates. By analysing the relationship of annual crop yield and cropland area changes, we see potential rebound effects of yield increases in tropical lowlands of low- to middle-income countries. …”
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Influence of model selection on optimal control of traffic for emissions minimisation by Khatun E Zannat, Judith Y T Wang, David P Watling

“…However, at a microscopic level (e.g. acceleration, deceleration rates, and deviations from the mean), pronounced differences became evident. …”
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Assessment of surgical site infections with antimicrobial resistance among cancer patients at a tertiary care hospital: A prospective study by Vishala Kundarapu, Akshay Shelke, Pallavi Priya, Shiwani Mishra, Richa Chauhan, Sameer Dhingra

“…Multidrug-resistant pathogens and high mortality rates emphasize the urgent need for improved infection control and antimicrobial stewardship in cancer care. …”
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Chronic Myeloid Leukemia: Part II—Cost of Care Among Patients in Advanced Phases or Later Lines of Therapy in Chronic Phase in the United States from a Commercial Perspective by Ehab L. Atallah, Rodrigo Maegawa, Dominick Latremouille-Viau, Carmine Rossi, Annie Guérin

“…Three-month outpatient incidence rates (IRs) were 7.6, 8.3, and 7.0 visits in the CML-CP On Treatment, CML-CP Post-Discontinuation, and CML-AP/BC cohort, respectively, with mean costs of $597 per service. …”
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Modelling the impact of non-pharmaceutical interventions on workplace transmission of SARS-CoV-2 in the home-delivery sector. by Carl A Whitfield, Martie van Tongeren, Yang Han, Hua Wei, Sarah Daniels, Martyn Regan, David W Denning, Arpana Verma, Lorenzo Pellis, Ian Hall, with the University of Manchester COVID-19 Modelling Group

“…<h4>Results</h4>The baseline model (without any interventions) showed different workplace infection rates for staff in different job roles. Based on our assumptions of contact patterns in the parcel delivery work setting we found that when a delivery driver was the index case, on average they infect only 0.14 other employees, while for warehouse and office workers this went up to 0.65 and 2.24 respectively. …”
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Annual trends in childhood fracture and injury in Beijing from 2010 to 2019 by Liu Zhiwei, Zhang Tao, Ye Xin, Lv Yanwei, Zhao Bin, Yang Zheng, Tian Zhaoxing

“…Conclusion Beijing children experienced progressively rising fracture and injury rates during the study decade, with notable increases in older age groups. …”
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Population increases of mountain forest birds are linked to forest regeneration after reduction of sulphur dioxide concentration in ambient air by Jiří Reif, Anna Gamero, Karolina Mikslová, Iva Hůnová

“…Since we did not prove a direct effect of SO _2 on bird annual population growth rates, we suggest that SO _2 influences bird populations indirectly via ecosystem processes.…”
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Host associations and genetic diversity of bat flies (Diptera: Nycteribiidae and Streblidae) in bats from Thailand by Dimas Novianto, Siwaporn Tuangpermsub, Thongchai Ngamprasertwong, Morakot Kaewthamasorn

“…Haplotype analyses identified 18 haplotypes in Raymondia, six in Brachytarsina, and two in Nycteribia, with evidence of site-specific host-parasite associations. Infestation rates varied by host species, sex, and location, with larger bat populations demonstrating higher infestation intensities. …”
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Men with psoriatic arthritis, rheumatoid arthritis and axial spondylarthritis have more children and at an earlier age than matched controls: results from a nationwide cohort by Gunnstein Bakland, Marianne Wallenius, Bjørg-Tilde Svanes Fevang, Anne Kjersti Daltveit, Solveig Hauge, Kjell Åsmund Salvesen, Gudrun David Sigmo, Hanne Brit Hetland, Maria Boge Lauvsnes

“…Information on children was obtained from the Medical Birth Registry of Norway. Fertility rates were compared between the patient/IJD groups and matched controls.Results In all IJD groups, fewer men were childless compared with the control groups (p&lt;0.001). …”
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The ratio of serum glucose to potassium is associated with poor prognosis in patients with severe acute myocardial infarction by Wen Pan, Teng-fei Ji, Jing Yang, Bing-tao Hu, Lei Lu, Jia-hong Xue

“…The primary outcomes assessed were all-cause mortality at 1 year and at 180 days. To compare survival rates across the four groups, Kaplan–Meier analysis was utilized. …”
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Social determinants of health and age-related differences in all-cause mortality: evidence from National Health and Nutrition Examination Survey by Siyuan Tan, Fanqi Li, Jiabao Zhou, Qiuzhen Lin, Qiming Liu

“…Kaplan–Meier curve analysis showed lower survival rates in the middle and high SDoH groups compared to the low SDoH group. …”
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Estimating the proportion of clinically suspected cholera cases that are true Vibrio cholerae infections: A systematic review and meta-analysis. by Kirsten E Wiens, Hanmeng Xu, Kaiyue Zou, John Mwaba, Justin Lessler, Espoir Bwenge Malembaka, Maya N Demby, Godfrey Bwire, Firdausi Qadri, Elizabeth C Lee, Andrew S Azman

“…Given the substantial variability in positivity between settings, extrapolations from suspected to confirmed cases, which is necessary to estimate cholera incidence rates without exhaustive testing, should be based on local data.…”
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Marangoni Convection of Self-Rewetting Fluid Layers with a Deformable Interface in a Square Enclosure and Driven by Imposed Nonuniform Heat Energy Fluxes by Bashir Elbousefi, William Schupbach, Kannan N. Premnath

“…In addition, an examination of the Nusselt number profiles reveals significant redistribution of the heat transfer rates in the SRF layers due to concomitant nonlinear thermocapillary effects.…”
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Developing Species-Age Cohorts from Forest Inventory and Analysis Data to Parameterize a Forest Landscape Model by Richard H. Odom, W. Mark Ford

“…Our results suggest that despite abundant precipitation and relatively low evapotranspiration rates for the region, low soil water holding capacity and fertility may be limiting factors for the spread of mesophytic species on excessively drained soils in the region. …”
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Analysis of sleep duration, energy intakes, physical activity, and metabolic syndrome based on the presence or absence of obesity and hypertension in working Korean adults by Eunsook Sung, Youngjun Lee, Sanghoo Kim, Jonghoon Park

“…BackgroundMetabolic syndrome poses a serious public health concern among working adults, especially in the context of increasing rates of obesity and hypertension. These lifestyle-related conditions are intricately linked to sleep patterns, dietary behaviors, and physical activity.ObjectiveThis study aimed to examine how sleep duration, energy intake, and physical activity levels—key lifestyle factors—are associated with metabolic syndrome based on the presence or absence of obesity and hypertension among working Korean adults.MethodsWe analyzed 6,503 working Korean adults aged 20–59 years using cross-sectional data from the Korea National Health and Nutrition Examination Survey covering 2016–2018. …”
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Sentiment Analysis Using a Large Language Model–Based Approach to Detect Opioids Mixed With Other Substances Via Social Media: Method Development and Validation by Muhammad Ahmad, Ildar Batyrshin, Grigori Sidorov

“… Abstract BackgroundThe opioid crisis poses a significant health challenge in the United States, with increasing overdoses and death rates due to opioids mixed with other illicit substances. …”
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3-D fracture network reconstruction and quantitative fractal analysis of subsurface rock fractures via integrated CT scanning and box-counting dimension methodology by Hongjian Wu, Xiangwei Kong, Xing Chen, Dianwei Guan

“…The inherent challenges posed by natural fracture networks and lithological disintegration in tight oil reservoirs significantly impede drilling integrity, completion efficiency, and hydrocarbon recovery rates. This study introduces a novel multi-scale quantitative characterization framework that fundamentally distinguishes itself from prior works through three key innovations. …”
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