Anticancer properties of copolymer nanoparticles loaded with Foeniculum vulgare derivatives in Hs578T and SUM159 cancer cell lines by Shima Bourang, Sodabeh Jahanbakhsh Godehkahriz, Mehran Noruzpour, Rasool Asghari Zakaria, Sergio Granados-Principal

“…Moreover, the drug release pattern illustrated a higher release rate from synthesized nanoparticles under acidic conditions (pH = 5). …”
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Transistor Structure with a Two-Dimensional Channel Electrophysical Parameters Interrelation Under Conditions of Instability by U. A. Zaitsau, D. A. Podryabinkin, V. V. Melnikova, A. L. Danilyuk

“…The influence on the electrical parameters of a transistor structure with a two-dimensional semiconductor channel of the band gap of the channel material, the thickness of the gate dielectric, and the capacitance of interface states is considered. …”
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Genome-wide associations spanning 194 in-hospital drug dosage change phenotypes highlight diverse genetic backgrounds in concurrent drug therapy by Alexander Pil Henriksen, Cristina Leal Rodríguez, Hannah Currant, Ioannis Louloudis, Jorge Hernansanz Biel, Maria Herrero-Zazo, Ewan Birney, Thomas Folkmann Hansen, Gianluca Mazzoni, Amalie Dahl Haue, Henning Bundgaard, Christian Erikstrup, Khoa Manh Dinh, Liam Quinn, Mie Topholm Bruun, Henrik Hjalgrim, Erik Sørensen, Christina Mikkelsen, Michael Schwinn, Ole Birger Vestager Pedersen, Henrik Ullum, Sisse Rye Ostrowski, Karina Banasik, Søren Brunak

“…As populations get older and medicine consumption rises, the rate of concurrent drug use and polypharmacy among patients is increasing. …”
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Epidemiological characterization of chronic myeloid leukaemia patients at an oncologic centre: A retrospective observational study by Ana Maria Meireles, Rita Calisto, Maria José Bento, Pedro Martinho Gouveia, Susana Bizarro, Manuel Teixeira, Cláudia Moreira, Ana Espírito Santo, Mário Mariz

“…At three months, the early molecular response rate was 77 %. At 12 months of treatment, of the 67 patients with response evaluation, 93 % achieved complete cytogenetic response and 49 % major molecular response. …”
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COVID-19 vaccine evidence monitoring assisted by artificial Intelligence: An emergency system implemented by the Public Health Agency of Canada to capture and describe the trajecto... by Su Hyun Lim, Mona Hersi, Ramya Krishnan, Joshua Montroy, Bonnie Rook, Kelly Farrah, Yung-En Chung, Adrienne Stevens, Joseline Zafack, Eva Wong, Nicole Forbes, April Killikelly, Kelsey Young, Matthew Tunis

“…Analysis of COVID-19 vaccine research patterns supports projections of research volume, type, and rate that will help predict resourcing and information needs to plan future emergency vaccine guidance activities.…”
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Leveraging a disulfidptosis-based signature to characterize heterogeneity and optimize treatment in multiple myeloma by Bingxin Zhang, Dong Zheng, Shuxia Zhu, Xinyi Zhang, Quanqiang Wang, Zhili Lin, Ziwei Zheng, Shujuan Zhou, Zixing Chen, Sisi Zheng, Enqing Lan, Luning Cui, Hansen Ying, Yu Zhang, Xuanru Lin, Qiang Zhuang, Honglan Qian, Xudong Hu, Yan Zhuang, Qianying Zhang, Zhouxiang Jin, Songfu Jiang, Yongyong Ma, Yongyong Ma, Yongyong Ma

“…Multiple myeloma (MM) is the second most prevalent hematologic malignancy characterized by a high synthesis rate of disulfide bond-rich proteins and chronic oxidative stress. …”
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Discovery and molecular identification of a new orthophasmavirus in the Asian citrus psyllid (Diaphorina citri) by Song Zhang, Song Zhang, Jing Chen, Jing Chen, Luqin Liu, Luqin Liu, Zhipeng Xie, Zhipeng Xie, Jiamei Liang, Jiamei Liang, Fulin Yan, Fulin Yan, Yaqin Song, Xuefeng Wang, Xuefeng Wang, Changyong Zhou, Changyong Zhou, Mengji Cao, Mengji Cao, Jinxiang Liu, Jinxiang Liu

“…It was also detected in progeny of infected ACPs and in the leaves fed upon by infected individuals. The infection rate of CLas was reduced in ACPs infected with DcBV2, and vice versa.DiscussionDcBV2 was fully sequenced and represents a new Orthophasmavirus species. …”
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Widespread geographic distribution of filarioid nematodes in caribou (Rangifer tarandus sspp.) in Canada by Aparna Mariyam Thomas, Guilherme G. Verocai, John Soghigian, Fabien Mavrot, Naima Jutha, Jan Adamczewski, Tracy Davison, Gwen Duytschaever, Arthur Fernandes, Allicia Kelly, Matthew R. Kulpa, Eve Lamontagne, Lisa-Marie Leclerc, Sara McCarthy, Ashley McLaren, Amanda D. Melin, Susan J. Kutz

“…The Arctic is currently experiencing an unprecedented rate of climate change, including warming temperatures and altered patterns of precipitation. …”
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Multi-omics analysis of Taiwanofungus gaoligongensis: effects of different cultivation methods on secondary metabolites by Tingwen He, Tingwen He, Tingwen He, Xiaolong Yuan, Liangjun Xiao, Tanggeran Hu, Yi Wang, Xiaolei Zhao, Xiaolei Zhao, Xiaolei Zhao, Lu Li, Lu Li, Chengbo Peng, Chengbo Peng, Chengbo Peng, Hongling Zhang, Hongling Zhang, Hongling Zhang, Yuan Zheng, Yuan Zheng, Yuan Zheng, Yuan Zheng

“…In particular, the expression of TgHMGR was markedly higher in NZJB than in XZJB and DM, correlating with the elevated terpenoids and triterpenoids levels, suggesting that TgHMGR may act as a key rate-limiting enzyme in the terpenoid biosynthesis pathway of T. gaoligongensis. …”
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Species Composition, Phenotypic and Genotypic Resistance Levels in Major Malaria Vectors in Teso North and Teso South Subcounties in Busia County, Western Kenya by Edward K. Githinji, Lucy W. Irungu, Paul N. Ndegwa, Maxwell G. Machani, Richard O. Amito, Brigid J. Kemei, Paul N. Murima, Geoffrey M. Ombui, Antony K. Wanjoya, Charles M. Mbogo, Evan M. Mathenge

“…Indoor resting mosquitoes had 100% mortality rate after 24 h since exposure. Overall SS genotypic frequency in Teso North and Teso South subcounties was 79.4% against 13.7% homozygous LL genotype and 6.9% heterozygous LS genotype. …”
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Estimation of long-term gridded cloud radiative kernel and radiative effects based on cloud fraction by X. Liu, T. He, Q. Wang, X. Xiao, Y. Ma, Y. Wang, S. Luo, L. Du, Z. Wu, Z. Wu

“…The GCF-CRKs exhibit similar signs and patterns and enhanced stability compared to existing kernels. …”
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Clinical Features of Liver Injury Induced by Immune Checkpoint Inhibitors in Japanese Patients by Koji Imoto, Motoyuki Kohjima, Tomonobu Hioki, Tomoyuki Kurashige, Miho Kurokawa, Shigeki Tashiro, Hideo Suzuki, Akifumi Kuwano, Masatake Tanaka, Seiji Okada, Masaki Kato, Yoshihiro Ogawa

“…Immune checkpoint inhibitors (ICIs) have improved the survival rate of patients carrying various malignant neoplasms. …”
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The Role of Intestinal Translocation in the Pathogenesis of Pneumonia in Acute Poisoning and the Contribution of Intestinal Lavage to Its Prevention and Resolution by V. A. Matkevich, T. T. Tkeshelashvili, A. G. Vorobyova, N. E. Stolbova, M. M. Potskhveriya, Yu. S. Goldfarb

“…Mortality among the patients with PPD poisoning decreased by 7 times, and with M and CS poisoning, as well as with AlD, there were no deaths, while in the respective comparison groups, the mortality rate for pneumonia was 5.1, 7.4, and 17.4 %, respectively. …”
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Near-Unity Nitrate to Ammonia conversion via reactant enrichment at the solid-liquid interface by Wanru Liao, Jun Wang, Yao Tan, Xin Zi, Changxu Liu, Qiyou Wang, Li Zhu, Cheng-Wei Kao, Ting-Shan Chan, Hongmei Li, Yali Zhang, Kang Liu, Chao Cai, Junwei Fu, Beidou Xi, Emiliano Cortés, Liyuan Chai, Min Liu

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Association of cancer and outcomes of patients hospitalized for COVID-19 between 2020 and 2023 [version 2; peer review: 1 approved, 2 approved with reservations, 1 not approved] by Robert F Terry, Rugiatu Z Kamara, Robert J Samuels, Donald S Grant, Sulaiman Lakoh, Mustapha Kabba, Innocent Nuwagira, Yusuf Sheku Tejan, Sia Morenike Tengbe, Ibrahim Franklyn Kamara, Shermarke Hassan, Abdulai Tejan Jalloh, Divya Nair, Laura Merson

“…Conclusions This study's findings underscore the heightened vulnerability of hospitalized COVID-19 patients with cancer, revealing a higher mortality rate, longer hospital stays, and an unstructured pattern of care that reflects the complexity of managing severely ill patients during a public health crisis like the COVID-19 pandemic.…”
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Habit-learning and decision-making circuits are susceptible to glycemic variability in type 2 diabetes: a longitudinal study by Carolina Moreno, Carolina Moreno, Carolina Moreno, Otília C. d’Almeida, Otília C. d’Almeida, Joana Crisóstomo, Nádia Canário, Leonor Gomes, Leonor Gomes, Leonor Gomes, Miguel Castelo-Branco, Miguel Castelo-Branco

“…Linear regression analysis showed that, for each increase of 1 mmol/L in MAGE value, the SPC of the temporal lobe decreases on average by 1.2% (higher atrophy rate).ConclusionThe relationship between longitudinal GM atrophy and GV has a regionally specific pattern, suggesting localized brain susceptibility to intra-daily glucose fluctuations. …”
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Viral characterization of the reassortants between canine influenza H3N2 and human pandemic (2009) H1N1 and avian H9N2 viruses in canine ex vivo tracheal explants by Tonia T. Kam, Christine H. T. Bui, Hin-Wo Yeung, Peter C. H. Wong, Alex W. H. Chin, John M. Nicholls, Malik Peiris, Kenrie P. Y. Hui, Leo L. M. Poon, Michael C. W. Chan

“…Results Co-passaging H3N2-CIV with human/avian influenza A viruses in canine tracheal explants resulted in a high rate of reassortment. Plaque-purified reassortants were all viable and able to propagate in mammalian alveolar epithelial cells. …”
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IMPACT OF THE INFLAMMATORY AND ISCHEMIC HEART DISEASE MARKERS INTO THE OVERALL CARDIOVASCULAR MORTALITY IN SENILE CITIZENS OF A LARGE CITY (THE DATA FROM SAHR TRIAL) by S. A. Shalnova, S. E. Evstifeeva, A. D. Deev, V. A. Metelskaya, A. V. Kapustina, G. A. Muromtseva, Yu. A. Balanova, E. M. Tuaeva, A. E. Imajeva, N. V. Kiseleva, M. A. Shkolnikova

“…For the assessment of current subclinical inflammation we used high-sensititvity C-reactive protein (hsCRP), interleucine 6 (IL-6), fibrinogen (FG), leucocytes, erythrocyte sedimentation rate (ESR). For CHD screening, we used standard ROse questionnaire and ECG pattern by Minnesota coding. …”
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A clinico-epidemiological study, assessing possible predictors of mortality and health-related quality of life for people living with visceral leishmaniasis – human immune virus (V... by Niyamat Ali Siddiqui, Dhruv Kumar Pandey, Ashish Kumar Singh, Sanjay Kumar Sinha, Mohd. Zahid Ansari, Rishikesh Kumar, Biplab Pal, Vidya Nand Rabi Das, Rajatashuvra Adhikary, Saurabh Jain, Krishna Pandey

“…These patients have a poor VL therapeutic success rate, more drug-related toxicity, and relapses resulting in high mortality. …”
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Clinical characteristics and outcomes of COVID-19 in kidney transplant recipients by R. O. Kantariya, Ya. G. Moysyuk, E. I. Prokopenko, A. R. Karapityan, A. A. Ammosov, A. V. Makevnina, A. A. Gaydarova

“…The comparison study of the clinical pattern, laboratory and instrumental test results, treatment features and outcomes was made.Results. …”
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