Circulating tsRNAs serve as potential biomarkers for predicting postoperative delirium in elderly patients receiving lower extremity orthopedic surgery by Angyang Cao, Angyang Cao, Rui Zhao, Rui Zhao, Chunqu Chen, Chunqu Chen, Can Wu, Can Wu, Yiwei Zhang, Yiwei Zhang, Changshun Huang, Changshun Huang, Binbin Zhu, Binbin Zhu

“…Propensity score matching was performed to balance demographic and clinical variables. The predictive value of candidate tsRNAs was assessed using ROC analysis, and their potential functions were explored through bioinformatic analyses.ResultsAmong 128 non-POD and 30 POD patients, two tsRNAs (Other-14: 31-tRNA-Gly-CCC-3 and Other-39: 73-tRNA-Arg-TCG-5) showed significantly elevated preoperative levels in POD patients (p<0.001).ROC analysis revealed strong predictive performance (AUC=0.868 and 0.956, respectively).These differences persisted in the propensity-matched cohort (29 pairs).Bioinformatic analyses indicated enrichment in pathways related to neurotransmission, inflammation, and metabolism.ConclusionThis study identified novel tsRNA biomarkers that robustly predict POD risk and provide insights into its molecular pathogenesis. …”
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TWO MUTATIONS CONCOMITANCE IN FEMALE PATIENT WITH ARRHYTHMIC TYPE OF NONCOMPACTION MYOCARDIUM SYNDROME by M. E. Polyak, A. A. Bukaeva, A. G. Shestak, O. V. Blagova, A. V. Sveshnikov, Yu. A. Lutokhina, A. V. Nedostup, E. V. Zaklyazminakaya

“…There is no consensual approach to classification, diagnostics, as treatment and management of patients with NCM till recently. Predictive value of the observed genetic mutations is not studied good enough too.Aim. …”
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The roles of nasal nitric oxide in diagnosis and endotypes of chronic rhinosinusitis with nasal polyps by Mengdi Zhu, Xuehuan Gao, Zhuang Zhu, Xiaoqing Hu, Hui Zhou, Jisheng Liu

“…For Eos CRSwNP diagnosis, nNO had high predictive value for Eos CRSwNP (AUC: 0.939; sensitivity: 76.74%; specificity: 96.67%; cut-off value: 231 ppb, p < 0.001). …”
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Evaluation of the prenatal diagnostic value of non-invasive prenatal testing for the detection of rare fetal autosomal trisomies: a single center study of 83,842 cases by Yiming Chen, Xiaoxia Wu, Huawei Li, Yixuan Yin, Yanzhen Zhang

“…Trisomy 1, 17 and 19 weren’t screened. The positive predictive value (PPV) for RATs in women at high-risk was 13.06%, and the PPVs for trisomy 9, 16, 15, 10 and 2 were 42.86%, 40.00%, 25.00%, 20.00%, and 16.67%, respectively. …”
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Enhanced tumor suppression in patient-derived temozolomide-resistant glioblastoma cells using a combination treatment of Olaparib and FK866 by Xiaowei Sha, Jiaqian Li, Yunlong Fang, Jingjie Feng, Yasong Feng, Jing Wang, Yang Si, Feng Li, Shan Cheng, Wei Ding

“…In searching for potential marker molecules to indicate the effectiveness from the double inhibition of both NAMPT and PARP activities, we profiled the plasma-detectable circRNA species of cell subjected to the combination treatments, and identified the circPTTG1IP with a negatively of predictive value. Additional investigation suggested that NAMPT expression and cellular NAD + levels were regulated by circPTTG1IP, possibly involved its interaction with NAMPT targeting miRNAs.…”
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Predicting the risk of lean non-alcoholic fatty liver disease based on interpretable machine models in a Chinese T2DM population by Shixue Bao, Qiankai Jin, Tieqiao Wang, Yushan Mao, Guoqing Huang

“…The random forest model demonstrated superior performance compared to alternative machine learning (ML) algorithms, achieving an AUC of 0.739 (95% confidence interval [CI]: 0.676–0.802) in the training set, and it also exhibited the best predictive value in the internal validation set with an AUC of 0.789 (95% CI: 0.722–0.856). …”
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Comparative analysis of the prognostic significance of the CURB-65 and CRB-65 scores and their modifications in hospital mortality assessment in patients with community-acquired pn... by D. A. Vinokurova, E. S. Kulikov, S. V. Fedosenko, A. M. Gubareva, E. V. Pshevorskaya, P. V. Osipov, M. B. Arzhanik, E. A. Starovoitova, A. A. Arzhanik

“…In a population of 1,020 patients, which was subsequently split into test (n = 676) and training (n = 344) samples in the ratio 2 : 1, we compared the predictive value of the CURB-65 (confusion, urea &gt; 7 mmol / l, respiratory rate ≥ 30 / min, low blood pressure (BP), and age ≥ 65 years) and CRB-65 (confusion, respiratory rate ≥ 30 / min, low blood pressure (BP), and age ≥ 65 years) scores in identifying patients at high risk of in-hospital death. …”
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Analyses of proximal adjacent segment degeneration and prognostic factors after lumbar fusion surgery: study based on proximal facet joint angle by Feng Qin, Weiqiang Fan, Lili Ren, Qi Chen, Xiaoxiao Chen, Wenjun Liu

“…Receiver operating characteristic (ROC) curves were used to assess predictive value. Results The high FJA group exhibited significantly higher rates of PASD compared with the low FJA group (P < 0.001). …”
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How to Estimate Fat Mass in Overweight and Obese Subjects by Lorenzo Maria Donini, Eleonora Poggiogalle, Valeria del Balzo, Carla Lubrano, Milena Faliva, Annalisa Opizzi, Simone Perna, Alessandro Pinto, Mariangela Rondanelli

“…These data are confirmed by the predictive value analysis where BMI showed a performance similar to a “coin flip.”…”
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Comparison between an adapted protocol for home and ambulatory measurement for evaluating night-time blood pressure behaviour by Thamyres Costa Borges, Priscila Valverde de Oliveira Vitorino, Sayuri Inuzuka, Ana Luiza Lima Sousa, Moisés Martins de Oliveira, Carlos Augusto Pícoli de Andrade, Rodrigo Bezerra, Audes Diógenes Magalhães Feitosa, Weimar Kunz Sebba Barroso

“…Total HBPM outperformed daytime and evening HBPM in detecting abnormalities on ABPM (daytime, night-time, and 24 h), with higher sensitivity, negative predictive value (NPV), AUC, concordance index, and Kappa coefficient. …”
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Relationship Between Physical Fitness Attributes and Dynamic Knee Valgus in Adolescent Basketball Athletes by Aleksandar Stojiljkovic, Eleni Karagianni, Varsamo Antoniou, Garyfallia Pepera

“…Given the strong predictive value of VO₂max and LLMP for knee control, targeted training programs focusing on neuromuscular conditioning and aerobic capacity may be effective for injury prevention.…”
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Frailty as a predictor of postoperative morbidity and mortality in older patients undergoing emergency laparotomy: a prospective cohort study in Yemen by Waleed Mohammed Gilan, Yasser Abdurabo Obadiel, Ameen Fuad Hashem, Shehab Abdulhameed Aiash, Haitham Mohammed Jowah

“…This study aimed to evaluate the predictive value of frailty, assessed using the Clinical Frailty Scale (CFS), for postoperative morbidity and 30-day mortality in patients aged ≥ 60 years who underwent EL in Sana’a, Yemen. …”
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Clinical value of combined detection of serum ferritin and N-terminal pro-brain natriuretic peptide in the assessment of Kawasaki disease in children over 1 year of age by Zhen-qing Liu, Wan-yu Jia, Peng Li, Chun-lan Song

“…Abstract Background To compare the expression levels of serum ferritin and plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) in children over 1 year with Kawasaki disease (KD) and explore the early predictive value of the combined detection of these two indicators for the occurrence of intravenous immunoglobulin (IVIG) resistance and coronary artery lesions (CALs) in KD patients. …”
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Retrospective analysis of the clinical significance of Ro52/TRIM21 antibody and specific antinuclear antibody patterns by indirect immunofluorescence by Kaifang Liu, Yunfeng Liao, Pu Li, Jing Shi

“…Ro52 antibody showed high positive predictive value for primary Sjogren’s syndrome 25(96.15%), systemic lupus erythematosus 259(91.20%), connective tissue disease-associated interstitial lung disease 45(86.67%) and inflammatory myositis 60(86.67%). …”
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Preoperative albumin-bilirubin grade combined with sarcopenia predicts long-term outcomes after laparoscopic gastrectomy for advanced gastric cancer by Shuangshuang Hou, Yang Yu, Nanbo Li, Wenjing Yu, Zhiyuan Dai, He Li, Lianyi Guo, Jiajun Yin, Ju Wu

“…Abstract Background This retrospective study evaluated the predictive value of preoperative albumin–bilirubin (ALBI) grade combined with sarcopenia for the long-term prognosis of patients with advanced gastric cancer (AGC) undergoing laparoscopic radical surgery. …”
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Preoperative echocardiographic parameters influencing quality of life five years after coronary artery bypass graft surgery by Zdravković Marija, Ristić Miljko, Milić Nataša, Zdravković Darko, Krotin Mirjana, Ranđelović Tomislav

“…Echocardiographic parameters, that can easily be obtained preoperatively, have strong predictive value not only in postoperative survival, but also in determination of the quality of life of the patients five years after coronary artery bypass graft surgery.…”
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Evaluation of four clinical decision rules in children with minor head trauma: NEXUS II, PECARN, CHALICE, and CATCH by Majid Zamani, Farhad Heydari, Farzin Feyzollahi, Mehrdad Esmaillian, Amir Bahador Boroumand

“…Additionally, the negative predictive values (NPV) for these rules were 99.5% (95%CI 96.4–99.9) for the NEXUS II, 99.4% (95%CI 96.2–99.9) for the PECARN, and 98.8% (95%CI 95.8–99.7) for the CATCH and 98.8% (95%CI 95.7–99.7) for the CHALICE. …”
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Clinical utility of six serum tumor markers for the diagnosis of lung cancer by Yongchang Yang, Shuai Chang, Na Wang, Pengfei Song, Haijing Wei, Jie Liu

“…By analyzing a large cohort of patients with different stages and subtypes of lung cancer, we hoped to shed light on the predictive value and accuracy of each marker individually, as well as their combined performance. …”
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Genetic variants of SULT1A1 and XRCC1 genes and risk of lung cancer in Bangladeshi population by Tasnova Tasnim, Mir Md Abdullah Al-Mamun, Noor Ahmed Nahid, Md Reazul Islam, Mohd Nazmul Hasan Apu, Most Umme Bushra, Sikder Nahidul Islam Rabbi, Zabun Nahar, Jakir Ahmed Chowdhury, Maizbha Uddin Ahmed, Mohammad Safiqul Islam, Abul Hasnat

“…This study aimed to correlate the prognostic and/or predictive value of functional polymorphisms in SULT1A1 (rs9282861) and XRCC1 (rs25487) genes and lung cancer risk in Bangladeshi population. …”
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CELIAC DISEASE SCREENING IN A LARGE DOWN SYNDROME COHORT: COMPARISON OF DIAGNOSTIC YIELD OF DIFFERENT SEROLOGICAL SCREENING TESTS by Dilek Uludağ Alkaya, Seçil Sözen, Birol Öztürk, Nuray Kepil, Tülay Erkan, Hüseyin Tufan Kutlu, Beyhan Tüysüz

“…Overall, 2.3% of patients were diagnosed with CD. The positive predictive value of AGA-IgA and AGA-IgG was low (13.6% and 7.2%, respectively) compared to EMA (69.6%) and tTG-IgA (66.7%). …”
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