Validity of procalcitonin and C-reactive protein as biomarkers in diagnosis of neonatal sepsis in a referral hospital, Kenya by Florence Chepyegon Tum, Joseph J.N. Ngeranwa, Geoffrey K. Maiyoh, Frank G. Onyambu

“…The sensitivity, specificity, positive predictive value, negative predictive value and area under the curve for PCT were 93.3%, 98.1%, 97.6%, 94.6% and 0.959, whereas for CRP they were 100%, 72.8%, 74.3%, 100%, and 0.953, respectively.Conclusion and Recommendation The CRP test exhibited superior sensitivity, negative predictive value, but lower specificity, making it a more valuable tool for ruling out NS. …”
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Circulating microRNAs as specific biomarkers for breast cancer detection. by Enders K O Ng, Enders K O Ng, Rufina Li, Vivian Y Shin, Hong Chuan Jin, Candy P H Leung, Edmond S K Ma, Roberta Pang, Daniel Chua, Kent-Man Chu, W L Law, Simon Y K Law, Ronnie T P Poon, Ava Kwong

“…In the blind validation, these plasma markers yielded Receiver Operating Characteristic (ROC) curve area of 0.931. The positive predictive value was 88% and the negative predictive value was 92%. …”
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Frailty Assessment for Risk prediction in Gynecologic Oncology patients undergoing surgery and chemotherapy (FARGO) study protocol: Rationale and design of a multi-centre prospecti... by Julie My Van Nguyen, Danielle Vicus, Liat Hogen, Tiffany Zigras, Guillaume Paré, Michael Chong, Yetiani Roldan Benitez, P J Devereaux, Sandra Ofori, Flavia K Borges, Emily Di Sante, Denise Miletic, Olivia Panus, Jessica Vincent, Chinthanie Ramasundarahettige, Sofia Nene, Ameen Patel, Maura Marcucci

“…Secondary objectives include comparing the predictive value of the Frailty Phenotype with that of the Clinical Frailty Scale; evaluating the performance of a preoperative frailty assessments on other postoperative complications, chemotherapy tolerance, and 1-year recurrence-free survival; exploring the added predictive value of a dynamic perioperative frailty assessment repeated 28 days after surgery; assessing the acceptability of frailty assessments by physicians and patients; and establishing a biobank to investigate frailty biomarkers.…”
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Performance of scoring systems in selecting short stay medical admissions suitable for assessment in same day emergency care: an analysis of diagnostic accuracy in a UK hospital se... by Elizabeth Sapey, Suzy Gallier, Catherine Atkin, Vinay Reddy-Kolanu, Elizabeth Wallin

“…The positive predictive value of the Amb score in identifying those discharged within 12 hours was 54.5% (95% CI 53.3% to 55.8%). …”
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The diagnostic value of endometrial cytology in diagnosing endometrial pathology by Nadezhda Hinkova, Kamelia Tsvetanova, Tihomir Totev, Margarita Nikolova, Teodora Semova, Dimitar Dimitrov, Elitsa Petkova

“…We compared the cytological results to evaluate the test validity, including sensitivity, specificity, and negative and positive predictive value in the cases with endometrial carcinoma. …”
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Utility of computerized tomography in clinical staging and surgical decision making in patients with uterine cancer by Andrew Tannous, Alexzandra Adler, Jeanelle Sheeder, Rebecca J. Wolsky, Jill Alldredge

“…Diagnostic accuracy metrics (sensitivity, specificity, positive predictive value [PPV], negative predictive value [NPV]) were analyzed to assess the predictive value of CT for determining extrauterine disease, lymphadenopathy, and omental involvement. …”
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Use of ultrasonic elastography in the differential diagnosis of pancreatic cystic lesions by T. V. Dibina, E. S. Drozdov, A. P. Koshel, V. R. Latypov

“…Sensitivity, specificity, positive predictive value, negative predictive value, the overall accuracy of the technique accounted for 97, 75, 74, 97 and 84% respectively. …”
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Limited Diagnostic Value of Routine Screening of Neonates with the Urinary Group B Streptococcal Antigen Tests by Kai-Hsiang Hsu, Ming-Chou Chiang, Reyin Lien, Peng-Hong Yang, Shih-Ming Chu, Jen-Fu Hsu, Ren-Huei Fu

“…These data allowed calculation of the sensitivity (68.4%), specificity (99.4%), positive predictive value (24.5%), and negative predictive value (99.9%). …”
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Peak early‐phase enhancement ratio on contrast‐enhanced MRI to differentiate chromophobe renal cell carcinoma from oncocytoma by Deanna Thorson, Davide Bova, Maria M. Picken, Marcus L. Quek, Gopal N. Gupta, Hiten D. Patel

“…A PEER cutoff value of ≤1.05 had sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 100% for the averaged PEER measurements between the two radiologists. …”
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Comparison of Partec Rapid Malaria Test with Conventional Light Microscopy for Diagnosis of Malaria in Northwest Ethiopia by Meseret Birhanie

“…The sensitivity and specificity of Partec rapid malaria test were 93.8% (95% CI = 87.1%–100%) and 87.9% (95% CI = 79.7%–96.1%), respectively, while the positive predictive value and negative predictive value were 6.4% (95% CI = 77.2%–95.5%) and 94.6% (95% CI = 88.7%–100%), respectively. …”
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Novel genotyping algorithms for rare variants significantly improve the accuracy of Applied Biosystems™ Axiom™ array genotyping calls: Retrospective evaluation of UK Biobank array... by Orna Mizrahi-Man, Marcos H Woehrmann, Teresa A Webster, Jeremy Gollub, Adrian Bivol, Sara M Keeble, Katherine H Aull, Anuradha Mittal, Alan H Roter, Brant A Wong, Jeanette P Schmidt

“…However, in a study using the exome sequencing results of the first 50k individuals as reference (truth), it was observed that the positive predictive value (PPV) decreased along with the number of heterozygous array calls per variant. …”
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Early Clinical Predictors of Long-term Disability Progression in Patients with Multiple Sclerosis by Valentina Georgieva Ignatova, Lyudmila Pavlova Todorova, Lyubomir Haralanov Haralanov, Peter M. Vassilev

“…It has a sensitivity of 86%, specificity of 89%, positive predictive value of 85%, and negative predictive value of 81%. …”
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Diagnostic and Predictive Markers of Acute Lung Injury in Severe Concomitant Trauma by Ye. A. Kameneva, Ye. V. Grigoryev, G. A. Li, G. V. Vavin, A. S. Razumov

“…Objective: to define the diagnostic and predictive value of the markers of fat embolism as a cause of acute lung injury (ALI) in severe concomitant trauma. …”
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Evaluation of the Mycobacterium RealTime Kit Vircell (MRTVircell) Assay for Detecting <i>Mycobacterium</i> Species in Clinical Specimens by Maria Aguilera Franco, Antonio Sampedro Padilla, Juan Francisco Gutiérrez-Bautista, Adrián González Martínez, Fernando Cobo, José Gutiérrez-Fernández, Juan Antonio Reguera, Jose María Navarro Mari, Javier Rodríguez-Granger

“…For NTM detection, the sensitivity, specificity, positive predictive value, and negative predictive values were 28.17%, 99.29%, 83.33% and 91.63% for MRTVircell and 21.13%, 99.11%, 75%, and 91.67% for Anyplex MTB/NTM, respectively. …”
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Diagnostic value of electrocardiographic markers of left bundle branch block in predicting left ventricular reverse remodeling in patients receiving cardiac resynchronization thera... by L. M. Malishevsky, V. A. Kuznetsov, V. V. Todosiychuk, N. E. Shirokov, D. S. Lebedev

“…Among the ECG markers significantly associated with reverse remodeling during CRT, the absence of q wave in leads V5-V6 demonstrated the highest sensitivity (92,31%), a negative predictive value (70,59%) and overall accuracy (73,47%). …”
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Triglyceride-glucose index predicts ventricular aneurysm formation in acute ST-segment elevation myocardial infarction by Xiaobin Zeng, Yanyu Zhang, Xiaoshuang Xie, Jianjun Lan, Shiyang Li, Shiyang Li

“…The present study aimed to assess the predictive value of TyG index for left ventricular aneurysm (LVA) formation and prognosis in patients with acute ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI).MethodsThis prospective study included 991 patients with acute STEMI who underwent primary PCI. …”
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Chest ultrasound vs. Radiograph for pneumothorax diagnosis performed by emergency healthcare workers in the emergency department: a systematic review and meta-analysis by Jean-Baptiste Bouillon-Minois, Coline Burlet, Resa E. Lewiss, Reza Bagheri, Christophe Perrier, Jeannot Schmidt, Frédéric Dutheil

“…Chest ultrasonography had higher sensitivity (79.4%, 68.2 to 90.7) compared to chest X-ray (48.1%, 36.8 to 59.4), and a greater negative predictive value (chest ultrasonography = 94.3%, 91.2 to 97.3, and chest X-ray = 87.9%, 84.1 to 91.6). …”
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The Second Edition of the Milan System for Reporting Salivary Gland Cytopathology: System Application, Outcome, and Cytohistological Correlation by Magdalena Onyszczuk, Bogna Drozdzowska

“…The sensitivity, specificity, positive predictive value, and negative predictive value of FNA cytology in diagnosing salivary gland lesions using MSRSGC were found to be 76.5%, 100%, 100%, and 95.3%, respectively. …”
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A pilot evaluation of the artificial intelligence system CAD-EYE to optically characterise lesions in inflammatory bowel disease surveillance by Sherman Picardo, Shankar Menon, Kenji So, Kannan Venugopal, Wendy Cheng, Krish Ragunath

“…Results: CAD-EYE correctly characterised 92/97 lesions (94.8%) with a sensitivity of 80.0%, specificity of 97.6%, positive predictive value of 85.7% and negative predictive value of 96.4% for neoplastic lesions. …”
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Plasma Concentration of Calprotectin, but Not Serum Concentration, Is a Predictive Biomarker for Clinical Remission in Ulcerative Colitis by Sailish Honap, Isabelle Aimone-Gastin, Sylvain Salignac, Justine Flayac, Justine Paoli, Laurent Peyrin-Biroulet, Abderrahim Oussalah

“…Results: Plasma calprotectin concentration ≤10.5 ng/mL had a sensitivity of 98.6%, specificity of 100%, positive predictive value of 100%, negative predictive value of 96.3%, and an area under the receiver operating characteristic (AUROC) curve of 0.999 for diagnosing remission in patients with ulcerative colitis (UC). …”
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