Clinical value of the renal pathologic scoring system in complement-mediated thrombotic microangiopathy by Fei-Fei Chen, Xiao-Juan Yu, Hui Wang, Xu Zhang, Ying Tan, Zhen Qu, Su-Xia Wang, Feng Yu, Min Chen, Ming-Hui Zhao

“…Objectives This study was initiated to establish a renal thrombotic microangiopathy (TMA) scoring system based on clinical needs and investigate its predictive value for patients’ long-term outcomes.Methods Kidney biopsy-proven Complement-mediated TMA (C-TMA) patients from January 2000 to December 2017 in Peking University First Hospital were retrospectively studied. …”
Get full text

Short-term and long-term oncological outcomes of chemoradiotherapy for rectal cancer patients with or without oxaliplatin: a propensity score-matched retrospective analysis by Amirali Azimi, Fatemeh Sadat Tabatabaei, Kasra Kolahdouzan, Hamideh Rashidian, Forouzan Nourbakhsh, Maryam Abedini Parizi, Nima Mousavi Darzikolaee, Reyhaneh Bayani, Samaneh Salarvand, Azadeh Sharifian, Farzaneh Bagheri, Saeed Rezaei, Naeim Nabian, Reza Nazari, Negin Mohammadi, Mohammad Babaei, Marzieh Lashkari, Farshid Farhan, Mahdi Aghili, Felipe Couñago, Maria Antonietta Gambacorta, Reza Ghalehtaki

“…However, CAPEOX did not demonstrate any statistically significant predictive value for DFS (P = 0.500) or OS (P = 0.449). …”
Get full text

Prognostic significance of NT-proBNP and sST2 in patients with heart failure with preserved and mildly reduced ejection fraction by V. I. Podzolkov, N. A. Dragomiretskaya, A. V. Tolmacheva, I. I. Shvedov, A. A. Ivannikov, I. V. Akyol

“…At ROC analysis to one-year adverse events, both NT-proBNP and sST2 showed a significant predictive value in patients with EF >40% with an optimal cut-off value of 746 pg/ml (AUC 0.709; p = 0.005, sensitivity 62%, specificity 69%) and 27.1 ng/ml (AUC 0.742; p = 0.03, sensitivity 80%, specificity 75.8%) respectively.Conclusion: NT-proBNP levels >746 pg/ml and sST2 >27.1 ng/ml should be considered as predictors of poor prognosis in CHF patients with LVEF >40%.…”
Get full text

Postreperfusion Renal Allograft Biopsy Predicts Outcome of Single-Kidney Transplantation: A 10-Year Observational Study in China by Meifang Wang, Junhao Lv, Jie Zhao, Huiping Wang, Jianghua Chen, Jianyong Wu

“…We investigated the predictive value of postreperfusion biopsy on long-term allograft outcome after single-kidney transplantation. …”
Get full text

Prognostic impact of dynamic changes of type I melanoma antigen gene proteins CT7 (MAGE-C1/CT7) transcripts in multiple myeloma by Xuelin Dou, Fengrong Wang, Huan Chen, Yao Chen, Lei Wen, Yang Liu, Guorui Ruan, Xiaosu Zhao, Xiaojun Huang, Robert Peter Gale, Jin Lu, Jin Lu

“…Our data showed the predictive value of peri-ASCT frontline treatment. A 2-log decrease of MAGE-C1/CT7 post-induction cycle 2 compared to baseline correlated with a negative peri-ASCT MAGE-C1/CT7 status, providing an earlier prognostic marker of treatment response.…”
Get full text

Validation of the COAPT risk score in Polish patients undergoing transcatheter edge-to-edge repair of severe, functional mitral regurgitation: a multicenter, observational study by Karolina Jasińska-Gniadzik, Michał Łomiak, Jerzy Pręgowski, Zbigniew Chmielak, Piotr Kasprzyk, Jan Kasprzyk, Rafał Gałąska, Michał Chmielecki, Miłosz J. Jaguszewski, Marcin Fijałkowski, Aleksandra Topolska, Michał Sekuła, Marcin Grabowski, Janusz Kochman, Adam Rdzanek, Piotr Scislo, Agnieszka Kapłon-Cieślicka, Renata Główczyńska, Monika Budnik, Radosław Piątkowski, Łukasz Kołtowski, Arkadiusz Pietrasik, Aleksandra Gąsecka

“…CONCLUSIONS: In Polish patients fulfilling COAPT criteria, the COAPT risk score has moderate predictive value for post-procedural outcomes. In COAPT non-eligible patients, novel tools are required to predict outcomes.…”
Get full text

MULTISPIRAL COMPUTED TOMOGRAPHY VERSUS MYOCARDIAL BIOPSY IN DIAGNOSTICS OF YOCARDITIS AND PROGNOSIS EVALUATION OF DILATION CARDIOMYOPATHY SYNDROME by I. N. Alieva, O. V. Blagova, N. V. Gagarina, A. V. Nedostup, E. A. Kogan, V. P. Sedov, V. V. Kadochnikova, A. E. Donnikov, V. A. Zaydenov, A. G. Kupriyanova, S. K. Ternovoy

“…Sensitivity and specificity of all types of delayed accumulation in diagnostics of myocarditis were 63,3% and 78,7%, positive and negative predictive value 86,1% and 50,7%, subepicardial and transmural types — 49,0%, 83,0%, 85,7%, 43,8%, respectively. …”
Get full text

Stress hyperglycemia ratio as a biomarker for early mortality risk stratification in cardiovascular disease: a propensity-matched analysis by Mingxing Lei, Yan Li, Longcan Cheng, Nan Tang, Jie Song, Mi Song, QingQing Su, Mingxuan Liu, Shihui Fu, Feng Lin, Yuan Gao

“…The incremental predictive value of SHR support its utility for risk stratification, particularly for short-term outcomes, but its prognostic value fades for long-term mortalities. …”
Get full text

Evaluating the potential of phenotypic age to enhance cardiovascular risk prediction over chronological age in the UK Biobank by Kristine J. S. Kwan, Shi-Shuai Xie, Hai-Lei Li, Xue-Guang Lin, Yi-Jie Lu, Bo Chen, Kai-Xin Ge, Shu-Ya Tang, Hui Zhang, Shuai Jiang, Jing-Dong Tang

“…We applied a Cox regression model with time-dependent variables to assess the association between PhenoAgeAccel and incident CVD. The predictive value of PhenoAge and PhenoAgeAccel was evaluated with reference to the Framingham Risk Score (FRS) model using Kaplan-Meier curves, receiver operating characteristic curves (AUC), and Harrel’s C-index. …”
Get full text

CPAP modulation of sleep microstructure (N2-SSD and REM-AHI) as predictors of neurological recovery in ischemic stroke patients with moderate-to-severe OSA by Tianyu Jing, Tianyu Jing, Tianyu Jing, Liwen Xu, Liwen Xu, Shutong Sun, Wenyi Yu, Wenyi Yu, Yixi Zheng, Yixi Zheng, Gang Xu, Xinhao Shen, Tieyu Tang, Cheng Chu, Cheng Chu

“…Continuous positive airway pressure (CPAP) therapy is the primary treatment for stroke-related OSA; however, its positive effects on patient prognosis and the underlying mechanisms remain controversial.ObjectiveThis study aimed to investigate the impact of CPAP therapy on the recovery of IS patients with moderate-to-severe OSA and to identify biomarkers significantly associated with prognosis to assess their predictive value for short-term neurological outcomes. …”
Get full text

Risk factors of adverse outcome of COVID-19 and experience of Tocilizumab administration in patients on maintenance hemodialysis due to diabetic kidney disease by E. M. Zeltyn-Abramov, M. A. Lysenko, N. F. Frolova, T. N. Markova, N. I. Belavina, N. N. Klochkova, S. V. Kondrashkina, R. T. Iskhakov, A. I. Ushakova

“…For risk identification of upcoming lethal outcome a predictive model was created with the use of discovered RF as variables. The predictive value of this model is 92,45% (positive prognostic value — 96,5%, negative prognostic value — 87,5%).In TCZ treated subgroup the laboratory markers of adverse outcome were detected with application of correlation analysis. …”
Get full text

Triglyceride glucose-weight-adjusted waist index as a cardiovascular mortality predictor: incremental value beyond the establishment of TyG-related indices by Jiajun Qiu, Jin’e Li, Shan Xu, Jingqi Yang, Haixia Zeng, Yuying Zhang, Shiqi Yang, Lixuan Fang, Jiadian Huang, Hongtao Zhou, Jiaying Feng, Yujie Zan, Jia Zhan, Jianping Liu

“…Conclusion The current study is the first to validate that the TyG-WWI is a reliable risk prediction tool for cardiovascular death in the general population and has greater predictive value than traditional TyG-related parameters. …”
Get full text

Associations of Blood Pressure and Heart Rate and Their Contribution to the Development of Cardiovascular Complications and All-Cause Mortality in the Russian Population of 25-64 Y... by S. A. Shalnova, V. A. Kutsenko, A. V. Kapustina, E. B. Yarovaya, Yu. A. Balanova, S. E. Evstifeeva, A. E. Imaeva, S. A. Maksimov, G. A. Muromtseva, N. V. Kulakova, O. N. Kalachikova, T. M. Chernykh, O. A. Belova, G. V. Artamonova, E. V. Indukaeva, Yu. I. Grinshtein, R. A. Libis, D. V. Duplyakov, O. P. Rotar, I. A. Trubacheva, V. N. Serebryakova, A. Yu. Efanov, A. O. Konradi, S. A. Boytsov, O. M. Drapkina

“…To study the relationship of blood pressure (BP) and heart rate (HR) in a sample of men and women 25-64 years old and their predictive value for the development of fatal and non-fatal cardiovascular diseases (CVD) and mortality from all causes.Material and methods. …”
Get full text

A retrospective analysis of 6942 amniocentesis cases by Qingsha An, Yuxiao Huang, Feifei Yu, Yilun Tao, Juan Li, Xiaoze Li

“…The analysis encompassed the detection rate of chromosomal abnormalities via amniocentesis, the proportion and positive predictive value (PPV) of each indication group, the distribution of maternal age and gestational age, and the characteristic patterns of confirmed diagnostic findings. …”
Get full text

Multidrug-resistant Klebsiella pneumoniae coinfection with multiple microbes: a retrospective study on its risk factors and clinical outcomes by Xixi Song, Chonghe Xu, Zhongqi Zhu, Chenchen Zhang, Chao Qin, Juan Liu, Xiaoli Kong, Zhijun Zhu, Wei Xu, Mei Zhu

“…This study successfully established a predictive model based on risk factors, which has good predictive value for both patients with coinfections and those with CRKP. …”
Get full text

Development and external validation of a nomogram prediction model based on quantitative coronary angiography for predicting ischemic lesions: a multi-centre study by Shuai Yang, Shuai Yang, Shuang Leng, Shuang Leng, Zhouchi Wang, Jiang Ming Fam, Jiang Ming Fam, Adrian Fatt Hoe Low, Adrian Fatt Hoe Low, Ru-San Tan, Ru-San Tan, Ping Chai, Ping Chai, Lynette Teo, Lynette Teo, Chee Yang Chin, Chee Yang Chin, John C. Allen, Mark Yan-Yee Chan, Mark Yan-Yee Chan, Khung Keong Yeo, Khung Keong Yeo, Aaron Sung Lung Wong, Aaron Sung Lung Wong, Soo Teik Lim, Soo Teik Lim, Qinghua Wu, Liang Zhong, Liang Zhong, Liang Zhong

“…For per-patient analysis, the corresponding values were 85.8%, 85.7%, 86.0% in the development cohort and 82.2%, 83.3%, 81.1% in the validation cohort.ConclusionThe nomogram may be useful for predicting ischemic lesions using QCA measurements and the LASSO regression algorithm, with external validation indicating potential predictive value in cardiology care settings.…”
Get full text

Triglyceride glucose waist circumference and non alcoholic fatty liver disease: a systematic review and meta analysis by Ziyi Xin, Lanlan Feng, Qingwen Yu, Yongmin Shi, Ting Tang, Xuhan Tong, Siqi Hu, Yao You, Shenghui Zhang, Xingwei Zhang, Mingwei Wang, Jiake Tang

“…The triglyceride glucose-waist circumference (TyG-WC) index, a novel measure for assessing IR, may hold significant predictive value for NAFLD. However, the relationship between TyG-WC and the risk of NAFLD remains elusive. …”
Get full text

Serum LCAT as a Gender-Neutral Biomarker for Early Osteoporosis: A Multicenter Cohort Validation Study by Wen Y, Cheng S, Gou L, Zhou W, Li Y, Wang R, Wu J, Dai X, Gao M, Wang L, Xue B, Wang Y

“…Moreover, serum LCAT levels exhibited significantly higher predictive value for osteoporosis than that of conventional serum 25-hydroxyvitamin D (25OHD) levels.Conclusion: We demonstrate for the first time that reduced serum LCAT concentrations predict osteoporosis risk independently of confounding factors, qualifying it as a promising early-stage diagnostic biomarker. …”
Get full text

Elevated FDG uptake in non-tumorous lung regions does not predict immune checkpoint inhibitor–related pneumonitis in lung cancer patients by Friederike Völter, Friederike Völter, Friederike Völter, Lukas Wehlte, Blerina Resuli, Blerina Resuli, Blerina Resuli, Julia Walter, Julia Walter, Julia Walter, Lea Daisenberger, Maria Ingenerf, Maurice Heimer, Matthias Brendel, Matthias Brendel, Matthias Brendel, Gabriel T. Sheikh, Lena M. Unterrainer, Lena M. Unterrainer, Lena M. Unterrainer, Diego Kauffmann-Guerrero, Diego Kauffmann-Guerrero, Diego Kauffmann-Guerrero, Thomas Pfluger, Lucie Heinzerling, Lucie Heinzerling, Amanda Tufman, Amanda Tufman, Amanda Tufman

“…Logistic regression analyses were performed to identify the predictive value of pretreatment SUV for the development of cinrPneumonitis.ResultsA total of 239 patients were included, of whom 41 (17.2%) developed cinrPneumonitis. …”
Get full text

Development of a predictive model for metachronous liver metastasis in gastric cancer by Siyuan Wang, Siyuan Wang, Gaozan Zheng, Fengsu Wu, Ye Tian, Xinyu Qiao, Xinyu Dou, Hanjun Dan, Hanjun Dan, Guangming Ren, Liaoran Niu, Pengfei Wang, Lili Duan, Yumao Yang, Jianyong Zheng, Fan Feng

“…Besides conventional parameters, we identified and incorporated peripheral blood monocyte and lymphocyte counts as novel predictors, demonstrating their independent predictive value. Integrating these factors into nomogram could enhance predictive accuracy of MLM.…”
Get full text