Global Validation of a Model to Predict Reduced Estimated GFR in People With Type 2 Diabetes Without Diagnosis of CKD by Camilla Sammut-Powell, Rose Sisk, Estefania Vazquez-Mendez, Hardik Vasnawala, Susana Goncalves, Mark Edge, Rory Cameron

“…The model with regional adjustment achieved the target sensitivity (80.5%; 95% confidence interval [CI]: 78.8%–82.3%) and demonstrated a relative improvement of 51.5% (95% CI: 48.1%–55.1%) in the positive predictive value (PPV), compared to a screen-all approach. …”
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Photon-counting CT versus energy-integrating detectors for cardiac imaging: a systematic review of evidence from in vivo human studies on image quality and radiation dose by Magnar Rønning, Elias Johansen, Albertina Rusandu

“…Abstract Background Computed tomography (CT) is central to cardiovascular diagnostics, with coronary CT angiography (CCTA) widely used for evaluating coronary artery disease (CAD) due to its high sensitivity and negative predictive value. However, conventional energy-integrating detector (EID) CT is limited by reduced contrast resolution and artifacts, especially in patients with heavy calcification or stents, which can impair diagnostic accuracy. …”
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Identification of α2-macroglobulin as a biomarker for type 2 diabetes in human serum by Mingjie Wang, Limei He, Yuandi Chang, Zhaoli Yan

“…Receiver operating characteristic (ROC) curve analysis was employed to determine the predictive value of the differential proteins for the diagnosis of obesity and T2DM.ResultsIn this study, two-dimensional gel electrophoresis was used to analyze three groups. …”
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FAM64A silencing inhibits the proliferation, migration, invasion, and epithelial-mesenchymal transition in ovarian cancer cells via activating Hippo pathway by Jianxiu Luo, Ruiyang Li

“…Results We identified the 18 hub genes of OC with substantial predictive value. FAM64A was selected as a candidate gene. …”
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Sarcopenia in Urothelial Bladder Carcinoma: A Narrative Review by Constantin Radu Vrabie, Andreea Ioana Parosanu, Cornelia Nitipir

“…<i>Results</i>: In NMIBC treated with intravesical Bacillus Calmette–Guérin (BCG), sarcopenia has been shown to have a negative predictive value in some studies. Among patients receiving neoadjuvant chemotherapy (NAC) for MIBC, sarcopenia has been associated with increased toxicity, dose reductions, and treatment delays. …”
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Development of a nomogram model to predict 30-day mortality in ICU cancer patients with acute pulmonary embolism by Shuangping Li, Shenshen Huang, Yuxuan Feng, Yimin Mao

“…The nomogram model had a higher predictive value for 30-day mortality in patients with acute pulmonary embolism and cancer compared to the sPESI score (P < 0.05). …”
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Immunosenescence-Related Gene MAFF is Involved in Immune Regulation and Malignant Progression in Pancreatic Adenocarcinoma by Fenglin Zhang, Kexin Liu, Mengfan Ao, Jiangang Zhao, Xinghe Liao, Ping Li, Hao Chen

“…This research sought to examine the predictive value and treatment implications of immunosenescence-related genes in PAAD. …”
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Record linkage without patient identifiers: Proof of concept using data from South Africa's national HIV program. by Khumbo Shumba, Jacob Bor, Cornelius Nattey, Dickman Gareta, Evelyn Lauren, William Macleod, Matthew P Fox, Adrian Puren, Koleka Mlisana, Dorina Onoya

“…Performance measures were sensitivity, positive predictive value (PPV), share of patients linked, and percent increase in data points. …”
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Diagnostic value of HMGB-1 and acetylcholinesterase in assessing the prognosis of patients with acute pancreatitis by Peng Guofei, Chen Wanfang, Li Yan, Zhang Danping

“…Finally, a 6-month prognostic follow-up was performed to analyse the predictive value of HMGB-1 and AChE for poor prognosis in AP using ROC curves. …”
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GABRINOX-2 protocol: a French, prospective, multicentre, randomised phase II trial evaluating gemcitabine/nab-paclitaxel followed by FOLFIRINOX versus FOLFIRINOX alone as first-lin... by Sophie Gourgou, Fabienne Portales, Marc Ychou, Catherine Fiess, Eric Assenat, Fanny Salasc

“…Additionally, we aim to identify novel biomarkers associated with treatment response through the analysis of circulating tumour DNA and assess the messenger RNA signature’s predictive value for OS based on treatment approach.Ethics and dissemination This study was approved by the comité de protection des personnes Ile de France III (26 July 2021) and the French National Agency for the Safety of Health Products (17 September 2021). …”
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Association of HLA-DRA expression with prognosis and tumor microenvironment in clear cell renal cell carcinoma by Shu-Xin Qu, Xiang Wang, Wan-Ru Han, Yu-Chen Ge, Bei Feng, Hai-Ying Guo, Xiao-Chen Sun, Kai Wang, Rui Cui

“…Diagnostic and prognostic models, including ROC curve and nomogram analyses, highlighted HLA-DRA’s predictive value. Immune infiltration analysis revealed strong associations between HLA-DRA expression and the infiltration of lymphocytes, chemokines, and chemokine receptors, with single-cell studies pinpointing monocyte macrophages as the primary source of HLA-DRA expression. …”
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ISUP grade upgrade prediction after radical prostatectomy: Role of Luteinizing Hormone to Testosterone ratio by Zhihua Pan, Ruizhe Zhao, Jinjiang Fan, Shaobo Zhang, Jie Li, Bianjiang Liu

“…Abstract Purpose This study aimed to evaluate the predictive value of the luteinizing hormone to testosterone (LH/T) ratio in postoperative International Society of Urological Pathology (ISUP) grade upgrading following radical prostatectomy. …”
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Incidence and mortality of acute kidney injury after cerebral hemorrhage in neurology care unit by WANG Rui, SHUI Hua, HU Hong-tao, HU Yu-gang, GAO Yue, HU Shuang

“…ObjectiveTo explore the incidence and mortality of acute kidney injury(AKI)in neurology care unit(NCU)am ong cerebral hem orrhage patients,and to determ ine the risk factors of the incidence of AKI and the m ortality of cerebral hem orrhage patients in NCU.M ethodsThe clinical data of 354 cerebral hem orrhage patients in NCU from January 2015 to M ay 2016 at Zhongnan hospital of W uhan University w ere collected retrospectively.Logistic regression w as done to analyze the risk factors of the incidence of AKI and the m ortality of cerebral hem orrhage patients in NCU,and then the receiver operating characteristic(ROC)curve w as used to evaluate the predictive value of these risk factors.ResultsAKI accounted for 35.3%in NCU am ong cerebral hem orrhage patients.The incidence of AKI w ith AKI stage 1,2,3 am ong patients w as 22.3%,5.1%and7.9%respectively.The total m ortality of cerebral hem orrhage patients in NCU w as 28.3%.The hospital m ortality of non-AKI patients in the NCU w as 7.0%,low er than 49.6%of AKI patients(P<0.01).The m ortality of AKI w ith AKI stage 1,2,3 am ong patients w as 39.2%,55.6%and 75.0%respectively.Logistic regression suggested that hydragogue(OR=1.796),m echanical ventilation(OR=1.728),and APAC H EⅡscores(OR=1.153)w ere the independent risk factors of AKI.AKI(OR=5.452),anem ia(OR=2.7 6),age(OR=1.025),and APAC H EⅡscores(OR=1.198)w ere the independent risk factors of m ortality.For AKI and NCU m ortality,APAC H EⅡscores had the good correctness of prediction.ConclusionsAKI is a com m on com plication am ong cerebral hem orrhage patients in NCU,and can significantly increase NCU m ortality.W e should take early detection for AKI seriously and m ake early prevention,w hich m ight be effective to decrease NCU hospital m ortality.…”
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Prognostic value of glycemic gap in ST-segment elevation myocardial infarction-associated acute kidney injury by Xiaofu Zhang, Yong Li, Qinghuan Yang, Siwen Wu, Yang Song, Ziyun Luo, Jianping Xu

“…This study aims to explore the predictive value of GG for the risk of STAAKI after percutaneous coronary intervention (PCI) in STEMI patients. …”
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PO25 | Baseline thrombin generation test does not predict thrombotic events in acute leukemia: a monocentric prospective study

“…Conventional coagulation assays (CCAs) and platelet count offer limited predictive value. Global coagulation assays such as thrombin generation assay (TGA) may provide a more comprehensive picture of the hemostatic state. …”
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Human neutrophil lipocalin, procalcitonin, c-reactive protein, and leucocyte count for prediction of bacterial sepsis in emergency department patients by Jonathan Benhamou, Ricardo Nieves-Ortega, Christian H. Nickel, Alina Lampart, Tobias Kuster, Gianmarco M. Balestra, Christiane Rosin, Christoph Becker, Kriemhild Lippay, Roland Bingisser

“…A combination of serum HNL with NEWS and SOFA at presentation had the best predictive value for bacterial sepsis at 48 h after ED presentation (AUC 0.83). …”
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Association between geriatric nutritional risk index and In-Hospital mortality in acute aortic dissection patients: a retrospective cohort study by Lingyu Lin, Sailan Li, Yanchun Peng, Qiong Pan, Ni Hong, Liangwan Chen, Yanjuan Lin

“…This study sought to explore the predictive value of GNRI for in-hospital mortality in patients with AAAD. …”
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A Pilot Study on Thermal Comfort in Young Adults: Context-Aware Classification Using Machine Learning and Multimodal Sensors by Bibars Amangeldy, Timur Imankulov, Nurdaulet Tasmurzayev, Serik Aibagarov, Nurtugan Azatbekuly, Gulmira Dikhanbayeva, Aksultan Mukhanbet

“…The analysis also revealed that the predictive value of heart rate variability (HRV) diminished when richer physiological data, such as diastolic blood pressure, were included. …”
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Leveraging diverse cell death patterns in osteosarcoma patients and identification of the function of FADS2 in osteosarcoma cells by Guannan Bai, Shaobo Zhao, Lushan Chen, Manli Zhao, Wenhao Chen

“…After functional enrichment and somatic mutation analysis, a final PCD-related gene signature, involving the expression levels of CLTCL1, FADS2, and PLEKHF1, demonstrated significant predictive value. A nomogram including clinical characteristics and CDI was developed, which was verified to perform well. …”
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Undesirable events in the use of high-alert medicine geriatric patients at RSUPN Dr. Cipto Mangunkusumo by La Maliq malihi, Woro Supadmi, Yulia Trisna, Barkah Djaka Purwanto

“…Detect undesirable events due to the use of high-alert insulin and high-alert heparin drugs in geriatric patients at Rumah Sakit Umum Pusat Nasional (RSUPN) Dr Cipto Mangunkusumo using the trigger tool method based on positive predictive value (PPV) and determine the effect of using high-alert insulin and high alert heparin drugs on undesirable events. …”
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