Assessment of pulmonary embolism probability using a machine learning model by D. V. Gavrilov, A. E. Andreichenko, A. D. Ermak, T. Yu. Kuznetsova, A. V. Gusev

“…The following signs had the greatest prediction value: cough, respiratory disorders, blood creatinine, body temperature, general weakness, heart rate, respiratory rate, edema, antihypertensive therapy, saturation and age.Conclusion. …”
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Electrical cardiometry for early detection of hemodynamically significant patent ductus arteriosus in preterm infants by Rania A. El-Farrash, MD, Adham M. El-Tahry, MD, Mariam N. Farag, MSc, Dina M. Shinkar, MD

“…The area under the curve for CO was 0.751 and the cut-off point was ≤0.53 L/min, with sensitivity of 63.64 %, specificity of 78.57 %, positive predictive value of 70.0 %, and negative predictive value of 73.3 %. …”
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Two sides of the coin: coagulation and inflammation in deep vein thrombosis – a prospective study on D-dimer and SIRI by Ercan Kahraman, Sirin Cetin, Meryem Cetin, Ayse Ulgen, Ayse Ulgen

“…Additionally, the combination of SIRI and D-dimer yielded high positive and negative predictive values for DVT diagnosis.…”
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A telomere-related signature for predicting prognosis and assessing immune microenvironment in osteosarcoma by Shihao Li, Lina Zhang, Haiyang Zhang

“…In addition, the telomere-related signature demonstrated predictive value for the immune microenvironment and drug sensitivity in osteosarcoma. …”
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Control nutritional status score and platelet/lymphocyte ratio relationship with left ventricular hypertrophy in peritoneal dialysispatients by QUAN Yu-di, ZHOU Qiao, FENG Jin-hong, ZHANG Ying

“…Objective Using controlling nutritional status（CONUT） score and platelet to lymphocyte ratio（PLR）,to evaluate the nutritional status and inflammation status of patients with peritoneal dialysis（PD）,and analyze their relationship with left ventricular hypertrophy.Methods The patients undergoing peritoneal dialysis in Department of Nephrology,Affiliated Hospital of Xuzhou Medical University from January 2019 to May 2020 were enrolled.General patient information and laboratory indicators were collected.Cardiac color Doppler ultrasound was used to assess changes in the patient’s cardiac structure.According to the presence or absence of left ventricular hypertrophy（LVH）,the patients were divided into LVH group and non-LVH group.Each indicator was compared between the two groups,and risk factors of LVH were analyzed by logistic regression method.ROC curve was used to analyze the sensitivity and specificity of PLR and CONUT in diagnosing LVH.Results（1） A total of 82 patients were included,and the incidence of LVH was 40.2%.Systolic blood pressure,uric acid,PLR and CONUT scores of the LVH group were significantly higher than those of the non-LVH group; and Hb,LVEF and Alb were significantly lower than those of the non-LVH group（P<0.05）,with statistical significance.（2） Logistic regression analysis showed that systolic blood pressure,PLR and CONUT score were all risk factors affecting left ventricular hypertrophy.（3）The areas under the curve of LVH ROC curve analysis found that,the areas under the curve of LVH PLR and CONUT score predicted in PD patients were 0.743 and 0.822,respectively,and the combined prediction value was 0.855.Conclusions CONUT score and PLR are associated with LVH in peritoneal dialysis patients,and are the influencing factors of LVH.The combination between CONUT score and PLR is more valuable in predicting LVH in PD patients.…”
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Stratified Multisource Optical Coherence Tomography Integration and Cross-Pathology Validation Framework for Automated Retinal Diagnostics by Michael Sher, Riah Sharma, David Remyes, Daniel Nasef, Demarcus Nasef, Milan Toma

“…Clinical utility metrics prioritized alignment with ophthalmological imperatives, emphasizing negative predictive value to minimize false negatives and enhance diagnostic reliability. …”
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Relationship between history of falls and foot pressure centre parameters during gait and stance in patients with lower-limb osteoarthritis by Yuya Mawarikado, Yosuke Uchihashi, Yusuke Inagaki, Munehiro Ogawa, Yoshinobu Uchihara, Naoto Seriu, Yukako Ishida, Yasuyo Kobayashi, Asuka Sakata, Keiji Nogami, Midori Shima, Yasuhito Tanaka, Akira Kido

“…Further prospective studies are needed to determine its predictive value for fall prevention.…”
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Lysine methyltransferase 2D deficiency drives complete response to pembrolizumab in PD-L1-High cholangiocarcinoma: a case report and review of literature by Xiaofang Li, Xiaofang Li, Liao Wang, Liao Wang, Shuang Li, Shuang Li

“…Conventional biomarkers like PD-L1 expression show limited predictive value, creating an urgent need for novel therapeutic targets in this aggressive malignancy.Case presentationWe describe a stage IV ICC patient with PD-L1 positivity and a somatic KMT2D mutation (p.R5303C) who attained sustained complete remission after pembrolizumab treatment, despite developing severe multi-organ immune-related adverse events (irAEs) including hepatitis, pneumonitis, and thrombocytopenia. …”
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Combined preoperative platelet-albumin ratio and cancer inflammation prognostic index predicts prognosis in colorectal cancer: a retrospective study by Kuan Wang, Kejin Li, Ziyi Zhang, Xiangyue Zeng, Zhimin Wu, Boxiang Zhang, Yipeng Pan, Lucy Yue Lau, Zeliang Zhao, Yi Chen

“…In this study, we investigated the predictive value of two easy-to-measure preoperative markers, platelet-to-albumin ratio (PAR) and cancer inflammation prognostic index (CIPI), in postoperative survival of patients with CRC. …”
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Brief Communication: Maternal Plasma Autoantibodies Screening in Fetal Down Syndrome by Karol Charkiewicz, Monika Zbucka-Kretowska, Joanna Goscik, Slawomir Wolczynski, Adam Lemancewicz, Piotr Laudanski

“…The second step was to create a classifier of Down syndrome pregnancy, which includes 14 antibodies. The predictive value of the classifier (specificity and sensitivity) is 100%, classification errors, 0%, cross-validation errors, 0%. …”
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Impact of the “L” score from the RENAL nephrometry score on RAPN surgical outcomes in medial versus lateral renal tumors by Yasuhiro Numata, Hiroki Ito, Seiichiro Honda, Kota Kobayashi, Ryosuke Jikuya, Tomoyuki Tatenuma, Go Noguchi, Daiki Ueno, Mitsuru Komeya, Yusuke Ito, Kentaro Muraoka, Kazuki Kobayashi, Hisashi Hasumi, Kazuhide Makiyama

“…In conclusion, significance of the “L” score on surgical outcomes differs between medial and lateral tumors and it is strongly associated with outcomes in medial tumors, whereas its predictive value in lateral tumors is less marked. The RENAL nephrometry score lacks differentiation between medial and lateral tumors; therefore, surgeons should interpret “L” scores with caution.…”
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Clinicopathological and Survival Outcomes of Well-Differentiated Thyroid Carcinoma Undergoing Dedifferentiation: A Retrospective Study from FUSCC by Ben Ma, Weibo Xu, Wenjun Wei, Duo Wen, Zhongwu Lu, Shuwen Yang, Tongzhen Chen, Yulong Wang, Yu Wang, Qinghai Ji

“…Harrell index of concordance (C-index) and Akaike information criterion (AIC) were calculated to compare the predictive value for prognosis among several prognostic classification systems. …”
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Ablation Lesion Assessment with MRI by Lluís Mont, Ivo Roca-Luque, Till F Althoff

“…With a negative predictive value close to 100% it can reliably rule out pulmonary vein reconnection non-invasively and thus may avoid unnecessary invasive repeat procedures where a pulmonary vein isolation only approach is pursued. …”
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Utility of ultrasound examination in the diagnosis of laryngeal and hypopharyngeal cancers by G. F. Allakhverdieva, G. T. Sinyukova, T. Yu. Danzanova, E. V. Kovaleva, О. A. Saprina, E. A. Gudilina

“…US examination demonstrated a sensitivity of 94.1 %, accuracy of 91.9 %, efficacy of 47.0 %, and positive predictive value of 97.5 %. Specificity was not evaluated since we had no negative results.Conclusion. …”
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Ophthalmologic Psychophysical Tests Support OCT Findings in Mild Alzheimer’s Disease by Elena Salobrar-Garcia, Rosa de Hoz, Blanca Rojas, Ana I. Ramirez, Juan J. Salazar, Raquel Yubero, Pedro Gil, Alberto Triviño, José M. Ramirez

“…The PTs with the greatest predictive value are the higher spatial frequencies in CS and tritan unspecific errors in CP. …”
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Association between obesity indicators and retinopathy in US adults: NHANES 2005–2008 by Chuan-Xi Wang, Miao Kuang, Miao Kuang, Jing-Jing Hou, Si-Yu Lin, Sheng-Zhen Liu, Ning Bao, Zheng-Xuan Jiang

“…ROC curves showed that WWI had the highest predictive value for retinopathy.ConclusionOverall, increased levels of these obesity indicators increase the likelihood of developing retinopathy.…”
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Copeptin: Limited Usefulness in Early Stroke Differentiation? by Johannes von Recum, Julia Searle, Anna Slagman, Jörn Ole Vollert, Matthias Endres, Martin Möckel, Martin Ebinger

“…The diagnostic accuracy of copeptin for IS was 63% with a sensitivity of 80% and a positive predictive value of 64%. Conclusion. In this cohort of patients copeptin-levels within 4.5 hours of symptom onset were higher in patients with IS compared to TIA but the broad range of values in stroke-mimics limits diagnostic accuracy. …”
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A nomogram for predicting non-curative resection in patients with early gastric cancer based on white light imaging by Mengyu Cao, Linlin Ren, Congcong Min, Zeyuan Diao, Hao Chen, Hua Liu, Xiaoyu Li, Jiahui Xu, Zibin Tian, Tao Mao

“…The nomogram based on these features showed good predictive value for NCR, with an area under the curve (AUC) of 0.8095 (95% CI: 0.7538–0.8651) in the training set and 0.7567 (95% CI: 0.6427–0.8707) in the validation set. …”
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A Selective Chromogenic Medium for Detecting Meropenem-Resistant <i>Pseudomonas aeruginosa</i> in Respiratory Samples by Carmen Cintora Mairal, Guillermo Martín-Gutiérrez, Ángel Rodríguez-Villodres, José Miguel Cisneros, José Antonio Lepe, José Manuel Ortiz de la Rosa

“…<b>Results</b>: The selective medium demonstrated excellent sensitivity (average 98.7%) and specificity (average 90%) across bacterial concentrations ranging from 1 × 10⁴ to 1 × 10⁸ CFU/mL, and a high negative predictive value (average 99.2%) compared to the broth microdilution (BMD) method. …”
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Irisin: An influential perspective on the protective effect of metformin on aortic and cardiac aging in rats by Ozgur Baris, Gulcin Gacar, Burak Acar, Feride Ipek Komsuoglu Celikyurt, Yusufhan Yazir, Tijen Utkan

“…It regulates energy metabolism, fat tissue and glucose metabolism. The predictive value of irisin for the effects of metformin on cardiac and aortic aging in an aged rat model was evaluated by quantitative and histological confirmation. …”
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