Study protocol for an observational cohort evaluating incidence and clinical relevance of perioperative elevation of high-sensitivity troponin I and N-terminal pro-brain natriureti... by Ekaterine Popova, Ángel Candela-Toha, María Alonso, Diego Parise, Míriam de Nadal, Ascencion Martin-Grande, Javier Pérez-Vélez, Juan Carlos Trujillo, Luis Gajate, Marcos de Miguel, Anna González-Tallada, Elisabeth Martínez-Téllez, Esther Cladellas-Gutierrez, Georgina Planas, Angélica de Pablo

“…Integrating both cardiac biomarkers may improve the predictive value for cardiovascular complications after lung resection. …”
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Time-restricted feeding protects against septic liver injury by reshaping gut microbiota and metabolite 3-hydroxybutyrate by Jing-Juan Hu, Fan Deng, Qi-Shun Sun, Qing-Ming Xiong, Yue Min, Si-Yuan Feng, Ze-Bin Lin, Peng-Han Chen, Zhen Hu, Ling Wu, Xiao-Feng Chen, Sun Xie, Wei-Feng Liu, Cai Li, Ke-Xuan Liu

“…Additionally, serum 3-HB levels were significantly positively correlated with L. murinus abundance and negatively correlated with liver injury indicators in septic patients, demonstrating a strong predictive value for septic liver injury (AUC = 0.8429). …”
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Triglyceride-glucose index as a predictor of one-year mortality in non-diabetic acute ischemic stroke by Shengyuan Wang, Xianjia Ning, Xianjia Ning, Xianjia Ning, Xianjia Ning, Jun Tu, Jun Tu, Jun Tu, Jinghua Wang, Jinghua Wang, Jinghua Wang, Jinghua Wang, Yu Zhao

“…Multivariate logistic regression and subgroup analyses were conducted to assess the predictive value of the TyG index for these outcomes.ResultsAmong the study population, 5.9% died within one year. …”
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Development and validation of a nomogram model for sleep disorders in patients with recurrent implantation failure based on physiological and lifestyle factors by You Zhang, Ningxin Qin, Jing Hu, Jie Bai, Mengjia Pan, Yan Xu, Xin Huang, Ke Wang, Ke Wang

“…The predictors include both physiological indicators and daily lifestyle habits, demonstrating significant predictive value and clinical application efficiency. It can be used for early identification of potential sleep disorders in RIF patients, providing certain reference significance for clinical work.…”
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Early Postoperative Increase in Transforming Growth Factor Beta-1 Predicts Microvascular Flap Loss in Reconstructive Surgery: A Prospective Cohort Study by Rihards Peteris Rocans, Janis Zarins, Evita Bine, Insana Mahauri, Renars Deksnis, Margarita Citovica, Simona Donina, Sabine Gravelsina, Anda Vilmane, Santa Rasa-Dzelzkaleja, Olegs Sabelnikovs, Biruta Mamaja

“…We aimed to investigate the predictive value of postoperative changes in transforming growth factor beta-1 (TGF-β1) for microvascular flap complications. …”
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Assessment of Long-Read Sequencing-Based Congenital Adrenal Hyperplasia Genotyping Assay for Newborns in Fujian, China by Xudong Wang, Xingxiu Lu, Faming Zheng, Kun Lin, Minjuan Liao, Yi Dong, Tiantian Chen, Ying He, Mei Lu, Jing Chen, Yanfang Li, Yulin Zhou

“…Finally, 66 neonates were diagnosed with CAH, with a positive predictive value of 28.82%. Based on this data, the overall prevalence of CAH in Fujian was estimated to be 1:26,883. …”
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Risk factors of bone metastasis in lung adenocarcinoma by Zhongnian Cao, Rong Zheng, Jing Li, Xuejuan Wang, Chao Ding, Fan Zhang, Jianhua Geng, Zhengmao Wei, Rong Fan

“…A receiver operating characteristic curve was used to verify the predictive value of the regression model, and the area under the curve was 0.912 (P < 0.001). …”
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Japanese experience of newborn screening for lysosomal storage diseases and adrenoleukodystrophy by Takanori Onuki, Makiko Tajika, Yohei Sugiyama, Masaru Shimura, Keiko Ichimoto, Toju Tanaka, Hiromi Nyuzuki, Motomichi Kosuga, Ohsuke Migita, Tetsuya Ito, Hideo Sasai, Ryosuke Bo, Junpei Hamada, Takashi Hamazaki, Norio Sakai, Takahito Inoue, Kimitoshi Nakamura, Torayuki Okuyama, Kei Murayama

“…In contrast, the positive predictive value was low and false-positive rates was elevated, particularly for PD, MPS II, and ALD, have been attributed to pseudodeficiency alleles and methodological differences. …”
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The Combined Prognostic Value of 18F‐FDG PET/CT Metabolic Parameters of Immune Organs and Hematological Immune‐Related Markers in Patients With Locally Advanced Cervical Cancer by Yi Li, Xin Wang, Yuanlin Li, Wanhu Li, Defeng Liu, Longxiang Guo, Xiuli Liu, Zhichao Li, Ao Liu, Minghuan Li

“…Conclusion The nomograms based on metabolic parameters of immune organs and hematological immune‐related markers demonstrated high predictive value for patients with LACC undergoing CCRT. …”
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Mechanism and Predictive Role of NUB1 Protein in Oestrogen Receptor Pathway of FEC-Treated Breast Cancer Patients by Maria Arshad, Amira Raudhah Abdullah, Fuad Ismail, Francesco Pezzella, Azyani Yahaya, Geok-Chin Tan, Suet Lin Chia, Md Salzihan Md Salleh, Noraidatulakma Abdullah, Ka-Liong Tan

“…This study investigated NUB1’s predictive value in FEC treatment and its mechanistic interaction with the oestrogen receptor (ER) in BC. …”
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Optimized design and performance testing of hydraulic electrostatic actuator by Yuze Ye, Qingsong He, Changli Yang, Xiaodong Xu, Lin Xie, Diyi Liu, Bo Zeng, Zhijian Leng

“…The experimental results of the actuation strain test show that the relative error between the test value and the model prediction value of 16.47% is less than 5%, and the optimization model results are reliable. …”
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Retroflex tongue as a non-invasive neurological marker of functional severity in older adults with ischemic stroke: a retrospective observational study by Yung-Sheng Huang, Yung-Sheng Huang, Hen-Hong Chang, Hen-Hong Chang, Hen-Hong Chang, John Y. Chiang, John Y. Chiang, Po-Chi Hsu, Po-Chi Hsu, Lun-Chien Lo, Lun-Chien Lo, Lun-Chien Lo

“…Retroflex tongue (RT) and tongue deviation (TD) are observable signs of cranial nerve dysfunction; however, their comparative predictive value for stroke severity remains unclear.MethodsIn this retrospective observational study, 308 older adults (mean age: 69.1 years) hospitalized with ischemic stroke were enrolled. …”
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Using sputum and tongue swab specimens for in-home point-of-care targeted universal testing for tuberculosis of household contacts: an acceptability and feasibility analysis by Adam Penn-Nicholson, Andrew Medina-Marino, Charl Bezuidenhout, Gesine Meyer-Rath, Lawrence Long, Matthew P Fox, Grant Theron, Morten Ruhwald, Brooke Nichols, Sharon Olifant, Kuhle Fiphaza, Maria Pieruccini, Bernard Fourie

“…This study assessed the acceptability of in-home targeted universal TB testing (TUTT) using GeneXpert MTB/RIF Ultra at point-of-care (POC) during household contact investigations (HCIs) and the feasibility of using sputum and tongue swab specimens.Methods The TB Home Study sought to evaluate the predictive value of different specimen types for use as a household-level triage test for TB. …”
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Machine learning-driven multi-omics analysis identifies a prognostic gene signature associated with programmed cell death and metabolism in hepatocellular carcinoma by Xiang Li, Donghao Yin, Jiahao Geng, Yanyu Xu, Zijing Xu, Xuemeng Yang, Quanwei Li, Zimeng Shang, Zhiyun Yang, Zhong Xu, Jiabo Wang, Enxiang Zhang, Xinhua Song

“…Results We developed an 18-gene signature based on PCD and metabolism with strong predictive value for overall survival (OS) in HCC patients. …”
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Systemic immune-inflammatory biomarkers combined with the CRP-albumin-lymphocyte index predict surgical site infection following posterior lumbar spinal fusion: a retrospective stu... by Zixiang Pang, Jiawei Liang, Jiayi Chen, Yangqin Ou, Qinmian Wu, Shengsheng Huang, Shengbin Huang, Yuanming Chen

“…This study develops machine learning models to assess the combined predictive value of Aggregate Index of Systemic Inflammation (AISI), Systemic Immune-Inflammation Index (SII), CRP-Albumin-Lymphocyte (CALLY) index and Subcutaneous Lumbar Spine Index (SLSI) for surgical site infection (SSI) following posterior lumbar spinal fusion.MethodsThis retrospective study analyzed 2,921 patients undergoing posterior lumbar spinal fusion at two tertiary hospitals in Guangxi (August 2017–January 2025). …”
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Sentinel lymph node biopsy experience in squamous cell carcinoma of the oral mucosa сT1–2N0M0 by F. E. Sevryukov, V. V. Polkin, Yu. A. Panaseikin, M. A. Sigov, R. F. Zibirov, I. A. Bekhtereva, S. A. Ivanov, A. D. Kaprin

“…The specificity of method was 95 %, the predictive value of a negative result was 0.04.Conclusion. …”
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Lung ultrasound for the diagnosis and monitoring of pneumonia in a tuberculosis-endemic setting: a prospective study by Phung Tran Huy Nhat, Luigi Pisani, Quoc-Khanh Tran-Le, Thanh Truc Thai, Nguyen Tran-Ngoc, Ngoc Duong-Minh, Lam Nguyen-Ho, Khoa Nguyen-Dang, Nam Vu-Hoai, Vu Le-Thuong

“…An improved LUSS effectively ruled out mortality (negative predictive value 97.4%).Conclusion Although LUS is highly sensitive for diagnosing CAP, its specificity in TB-endemic regions warrants further caution. …”
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Nocturnal hypoxemia is associated with poor pulmonary hemodynamics in patients with chronic thromboembolic pulmonary disease by Teng Han, Qiang Huang, Zhenguo Zhai, Xiaolei Zhang

“…Receiver operating characteristic (ROC) curves for the detection of a mPAP ≥ 25 mmHg, PVR > 3 WU and WHO FC III-IV indicated that nocturnal hypoxemia parameters had moderate predictive value. (T90: AUCmPAP=0.698, AUCPVR=0.733, AUCWHO−FC=0.729, respectively; MeanSpO2: AUCmPAP=0.691, AUCPVR=0.731, AUCWHO−FC=0.707, respectively). …”
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Case Report: Multi-cancer early detection utilizing blood-based genomics: Single-institution case series of novel cancer screening by Somya Khare, Jason C. Burton, Francis De Asis, Saron Mekonnen, Mason J. Stewart-McLellan, Diana Potts, Tiffani L. Howard, Nima Nabavizadeh, Nima Nabavizadeh

“…Cancer risk factors, outcomes of tests and studies performed due to MCED signal positive, time to diagnostic resolution, and treatment outcomes were obtained from chart-review.ResultsFrom January 2020 to December 2020, our institution enrolled 1735 participants (26% of total study enrollment), 27 of which returned a signal positive for cancer suspicion (1.6%), and ultimately 12 diagnosed cancers (true positives) for a positive predictive value of 44%. Four of 12 were recurrent cancers in participants more than three years from cancer therapy. …”
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The correlation between red blood cell distribution width to serum albumin ratio and all-cause mortality in critically ill patients with chronic obstructive pulmonary disease: a re... by Qianqian Zhang, Ling Liu, Ling Liu, Jing Zhou, Jing Zhou, Gang Teng, Yuanyuan Wang, Nianzhi Zhang

“…The red blood cell distribution width to albumin ratio (RAR), which reflects systemic inflammation and nutritional imbalance, has shown predictive value in chronic kidney disease and diabetes. …”
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