Association of cardiometabolic markers with hepatic steatosis and liver fibrosis in population without obesity and diabetes by Zhixing Fan, Chaojun Yang, Xiaojing Zhao, Jing Zhang

“…The AUC values of these four cardiac markers were greater than FLI, among which eGDR showed the highest predictive value (AUC = 0.781). In the hepatic steatosis population, CMI (OR = 1.419, 95%CI: 1.033, 2.747), AIP (OR = 5.527, 95%CI: 1.082, 28.242), and TyG (OR = 2.345, 95%CI: 1.180, 4.661) were also showed significant association with liver fibrosis, while eGDR and FIB-4 were not associated with liver fibrosis. …”
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Relationship between neutrophil-to-lymphocyte ratio and pulmonary arterial hypertension in non-dialytic patients with chronic kidney disease stage 5 by 冯世尧, 任伟

“…Objective To investigate the clinical value of neutrophil-to-lymphocyte ratio(NLR)for pulmonary arterial hypertension(PAH)in non-dialytic patients with chronic kidney disease(CKD) stage 5.Methods A total of 144 non-dialysis patients with CKD stage 5 were divided into two groups:PAH group and non-PAH group according to pulmonary artery systolic pressure.Clinical data were compared between the two groups,Spearman correlation analysis was used to analyze the relationship between pulmonary artery systolic pressure and various factors.Binary classification Logistic regression analysis was applied to analyze the risk factors of PAH.Receiver operating characteristic(ROC)curve was adopted to evaluate the predictive value of NLR for PAH.Results There were 64 cases(44.4%)in the PAH group and 80 cases(55.6%)in the non-PAH group.NLR,platelet to lymphocyte ratio,left internal atrial diameter and main pulmonary internal artery diameter in the PAH group were significantly higher than those in the non-PAH group(P<0.05).Lymphocyte count,hemoglobin,serum iron,triglyceride,very low density lipoprotein cholesterol and left ventricular ejection fraction in the PAH group were significantly lower than those in the non-PAH group,with all statistically significant differences(P<0.05).NLR,left atrial diameter and main pulmonary artery diameter were positively correlated with pulmonary artery systolic pressure(P<0.05).Multivariate Logistic analysis showed that,NLR(OR=2.151,95%CI 1.438～3.218,P<0.001),left atrial diameter(OR=1.176,95%CI 1.068～1.294,P<0.05)and main pulmonary artery diameter(OR=1.229,95%CI 1.004～1.504,P<0.05)were independent risk factors for PAH.The results of ROC curve analysis showed that the area under curve of PAH predicted from NLR was 0.711(95% CI 0.626～0.797,P<0.05).When the NLR cutoff value was 3.23,the sensitivity and specificity for predicting the occurrence of PAH in non-dialysis patients with CKD stage 5 were 60.9% and 72.5%,respectively.Conclusions NLR has a good clinical value in predicting the occurrence of PAH in non-dialysis patients with CKD stage 5.Left atrial enlargement and main pulmonary artery enlargement were related to PAH.…”
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Association between sinusitis and incident rheumatic diseases: a population-based study by Ali Duarte-García, Kenneth J Warrington, Ashima Makol, Elena Myasoedova, Cynthia S Crowson, Jeffrey A Sparks, John M Davis, Vanessa L Kronzer, Andrew C Hanson, Robert Vassallo, Mattew J Koster, Alicia M Hinze, Kerry Wright

“…The primary exposure was presence of sinusitis, ascertained by diagnosis codes (positive predictive value 96%). We fit logistic regression models to estimate ORs for incident rheumatic diseases and disease groups, adjusted for confounders.Results We identified 1427 incident rheumatic disease cases and 4281 matched controls (mean age 63, 67% women, median 14 years electronic health record history). …”
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The impact of lacrimal gland characteristics on the clinical presentation of lacrimal gland prolapse in candidates for upper eyelid blepharoplasty by Bahram Eshraghi, Nahid Mirzaei, Samira Chaibakhsh, Ali Aghajani

“…The supine test demonstrated a 90% positive predictive value for LGP. Analysis of the prolapsed lacrimal gland characteristics indicated that the average length in patients with upright prolapse was significantly larger (8.33 ± 3.12 mm) than in those without (6.03 ± 2.91 mm, p = 0.001). …”
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A ROLE OF SUPEROXIDE DISMUTASE IN DEVELOPMENT OF POST-OPERATION ATRIAL FIBRILLATION IN CORONARY HEART DISEASE PATIENTS by O. A. Rubanenko, O. V. Fatenkov, S. M. Khokhlunov, L. V. Limareva

“…Patients with PSAF had III functional class of angina (72,4% vs 47,8%, р=0,028) and III functional class of congestive  heart failure (38,0% vs 7,5%, р=0,006), they had larger left atrium (43,5±4,1 mm vs 37,9±3,4 mm, р&lt;0,001).After multifactorial analysis, predictive value remained  for the following: left atrium larger than 41 mm — 5,1 (95% CI, 2,1-9,8, р=0,0005), SOD more than 2948 U/g — 4,4 (95% CI, 1,1-8,9, р=0,04).Conclusion. …”
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Association of serum lysophosphatidylcholine acyltransferase 3 levels with metabolic variables and risk of type 2 diabetes mellitus: A cross-sectional study. by Haifeng Zhu, Ziyi Zhong, Jing Jin, Wei Liu, Yuan Cao, Yawen Guo, Gaonian Zhao, Qian Li

“…Logistic regression evaluated the association between LPCAT3 levels and T2DM risk, and ROC analysis determined its predictive value.<h4>Results</h4>Median LPCAT3 level was lower in T2DM patients (21.51 ng/ml, IQR: 8.47-35.63) compared to the NGT group (24.43 ng/ml, IQR: 14.41-49.37). …”
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Life’s Crucial 9 score and chronic kidney disease: insights from NHANES 2005–2018 and the mediating role of systemic inflammation and oxidative stress by Shiyuan Qin, Jin Yang, Zili Wang, Pinglin He, Taotao Dong, Zhengyun Ren, Qiuyang Li

“…This study aimed to investigate the association between LC9 and CKD, compare its predictive value with LE8, and explore potential mediating mechanisms.MethodsThis study analyzed data from 16,431 participants in the National Health and Nutrition Examination Survey (NHANES) 2005–2018. …”
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Diabetes control in public assistance recipients and free/low-cost medical care program beneficiaries in Japan: a retrospective cross-sectional study by Daisuke Nishioka, Mitsuhiko Funakoshi, Seiji Haruguchi, Sakae Yonemura, Takashi Takebe, Misato Nonaka, Sanae Iwashita

“…Additionally, the adjusted OR was significantly higher in FLCMC programme beneficiaries aged ˂65 years (OR=2.57, 95% CI: 1.02 to 7.44) than in PARs.Conclusions This study highlights the predictive value of public assistance or the FLCMC programme for poor blood glucose control and suggests the inadequacy of current medical expense subsidies to eliminate health disparities in diabetes control.…”
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Prediction of lymph node metastasis in lung adenocarcinoma using a PET/CT radiomics-based ensemble learning model and its pathological basis by Shulin Li, Shulin Li, Fang Chen, Lei Wang, Lei Wang, Zhiming Xiang

“…The purpose of this study is to explore the predictive value of the stacking ensemble learning model based on 18F-FDG PET/CT radiomic features and clinical risk factors for LNM in lung adenocarcinoma, and elucidate the biological basis of predictive features through pathological analysis.MethodsNinety patients diagnosed with lung adenocarcinoma who underwent PET/CT were retrospectively analyzed and randomly divided into the training and testing sets in a 7:3 ratio. …”
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The relationship between coping styles and the utilization and misuse of industrial and traditional substances in psychiatric patients: a cross-sectional study from Iran by Reza Moshfeghinia, Sara Shirvani, Mohammadsadegh Kamran, Kasra Assadian, Arvin Hedayati, Arash Mani

“…These findings underscore the predictive value of coping styles in addiction vulnerability and support the development of coping-focused interventions.…”
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Genome‐wide screening of abberant methylated drivers combined with relative risk loci in bladder cancer by Chuanjie Zhang, Kangjie Shen, Yuxiao Zheng, Feng Qi, Jun Luo

“…In the validation group from GSE13507, 17 hub genes remained higher predictive value with AUC = 0.723 and patients in high‐risk group. …”
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Complete blood count (CBC)-derived indices at admission and short-term outcomes in ICU patients: a retrospective study by Ravi Shukla, Vinutha Silvanus, Sagar Dahal, Prasamsha Sitaula, Zenish Niraula, Chandan Kumar Gupta, Kiran Lamichhane

“…While TLC alone did not differ significantly between survivors and non-survivors.Conclusion Among CBC-derived parameters, the neutrophil-to-lymphocyte ratio had some predictive value for all-cause in-ICU mortality. Further research among etiology or diagnosis-specific cohorts of ICU patients that demonstrate dynamic changes in CBC-derived parameters may be needed to elucidate their role in patient outcomes.…”
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Triglyceride-glucose index and periodontitis: evidence from two population-based surveys by Jing Huang, Dan Zhang, Hua Li, Yiyun Zhang, Tianxue Long, Xiaojing Guo, Hangyu Cui, Zixuan Wei, Jun Zhao, Mingzi Li, Pangbo Wang, Pangbo Wang

“…ROC curves indicated that the predictive values of the TyG index were 8.24 (NHANES) and 8.69 (KNHANES). …”
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Comparison between an adapted protocol for home and ambulatory measurement for evaluating night-time blood pressure behaviour by Thamyres Costa Borges, Priscila Valverde de Oliveira Vitorino, Sayuri Inuzuka, Ana Luiza Lima Sousa, Moisés Martins de Oliveira, Carlos Augusto Pícoli de Andrade, Rodrigo Bezerra, Audes Diógenes Magalhães Feitosa, Weimar Kunz Sebba Barroso

“…Total HBPM outperformed daytime and evening HBPM in detecting abnormalities on ABPM (daytime, night-time, and 24 h), with higher sensitivity, negative predictive value (NPV), AUC, concordance index, and Kappa coefficient. …”
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Evaluation of four clinical decision rules in children with minor head trauma: NEXUS II, PECARN, CHALICE, and CATCH by Majid Zamani, Farhad Heydari, Farzin Feyzollahi, Mehrdad Esmaillian, Amir Bahador Boroumand

“…Additionally, the negative predictive values (NPV) for these rules were 99.5% (95%CI 96.4–99.9) for the NEXUS II, 99.4% (95%CI 96.2–99.9) for the PECARN, and 98.8% (95%CI 95.8–99.7) for the CATCH and 98.8% (95%CI 95.7–99.7) for the CHALICE. …”
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Peripheral Blood Inflammation Indicators as Predictive Factors for Treatment Response Assessed by MRI in Cervical Cancer Patients Referred for Radiotherapy by Chunyu Liang, Zhiyuan Xu, Guohui Yang, Jianxun Lv, Xinping Shen, Kusheng Wu

“…However, markedly different responses to RT are seen among patients with similar FIGO stages.The study aimed to evaluate the peripheral blood inflammation indicators that may have predictive value for treatment response in cervical cancer patients referred for RT. …”
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Role of Artificial Intelligence in the Diagnosis and Management of Pulmonary Embolism: A Comprehensive Review by Ahmad Moayad Naser, Rhea Vyas, Ahmed Ashraf Morgan, Abdul Mukhtadir Kalaiger, Amrin Kharawala, Sanjana Nagraj, Raksheeth Agarwal, Maisha Maliha, Shaunak Mangeshkar, Nikita Singh, Vikyath Satish, Sheetal Mathai, Leonidas Palaiodimos, Robert T. Faillace

“…A major advancement in this field was the FDA approval of the Aidoc© AI model, which has demonstrated high specificity and negative predictive value in PE diagnosis from imaging scans. Additionally, AI is being explored for optimizing anticoagulation strategies and predicting PE recurrence risk. …”
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Comparative performance of the InBios SCoV-2 DetectTM IgG ELISA and the in-house KWTRP ELISA in detecting SARS-CoV-2 spike IgG antibodies in Kenyan populations [version 2; peer rev... by Henry Karanja, Sophie Uyoga, Angela Karani, Daisy Mugo, Ambrose Agweyu, James Nyagwange, Bernadette Kutima, Boniface Karia, Philip Bejon, George M. Warimwe, Clayton Onyango, J Anthony G Scott, Kennedy Mwai, Eunice Wageci Kagucia, Makobu Kimani, John N Gitonga, Donald Akech, Antipa Sigilai, Abdhalah K. Ziraba, Monica Toroitich, Shirley Lidechi, Caroline Ochieng, Lynette I Ochola Oyier, Patrick K. Munywoki, Ifedayo M. O. Adetifa, James Tuju, Godfrey Bigogo

“…In all, the positive predictive value for InBios was 0.83 (95% CI, 0.79-0.87) and 0.98 (95% CI, 0.96-0.99) for KWTRP while the negative predictive value was 0.98 (95% CI, 0.97- 0.99) and 0.97 (95% CI, 0.95-0.98) for InBios and KWTRP respectively. …”
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Branched endovascular aortic aneurysm repair decreases platelet reactivity and platelet-rich thrombus formation – a prospective, cohort study by Aleksandra Gąsecka, Ewelina Błażejowska, Agata Konieczka, Mateusz Leśniewski, Magdalena Ostaszewska, Michał Łomiak, Magdalena Gajewska, Sylwester Rogula, Łukasz Szarpak, Krzysztof J. Filipiak, Mateusz Zawadka, Katarzyna Jama, Paweł Andruszkiewicz, Marcin Grabowski, Tomasz Jakimowicz

“…We aimed to assess the effect of bEVAR on platelet function and the predictive value of preoperative platelet function for postoperative bleeding. …”
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How to Estimate Fat Mass in Overweight and Obese Subjects by Lorenzo Maria Donini, Eleonora Poggiogalle, Valeria del Balzo, Carla Lubrano, Milena Faliva, Annalisa Opizzi, Simone Perna, Alessandro Pinto, Mariangela Rondanelli

“…These data are confirmed by the predictive value analysis where BMI showed a performance similar to a “coin flip.”…”
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