Mutation in the kras gene as a predictor of the effectiveness of immunotherapy for non-small cell lung cancer by K. K. Laktionov, A. M. Kazakov, K. A. Sarantseva, D. S. Scherbo, A. P. Koval

“…The review includes data from randomized clinical trials and meta-analyses on the predictive value of KRAS mutation status for response to immunotherapy in patients with NSCLC over the past 10 years.Results. …”
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Performance of the early warning system score in predicting postoperative complications in older versus younger patients by Annick Stolze, Lisette Vernooij, Dianne de Korte-de Boer, Markus W. Hollmann, Wolfgang F. F. A. Buhre, Christa Boer, Peter G. Noordzij, the TRACE Study Investigators Group

“…Abstract Background Early warning system (EWS) scores are implemented on surgical wards to identify patients at high risk of postoperative clinical deterioration, but its predictive value in older patients is unclear. This study assessed the prognostic value of EWS scores to predict severe postoperative complications in older patients compared to younger patients. …”
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Role of modified haematological sepsis score and red cell distribution width in early diagnosis of neonatal sepsis by Sweta Shanbhag, Rashmi Alva, Sudhir Prabhu H

“…RDW showed a fair sensitivity and a high negative predictive value when compared against blood culture and CRP. …”
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Prognostic value of serum NLR, PLR, P53, K67 level in lymph node metastasis of early gastric cancer by Long Xin, Shi Yingxi, Li Feifei, Wang Zhaojun, Wang Ying

“…Background: To explore the predictive value of relevant detection indexes and pathological serum NLR, PLR, P53, and K67 levels in lymph node metastasis (LNM) in patients with early gastric cancer (EGC) after radical surgery. …”
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Correlation between EpCAM expression and cervical lymph node metastasis in papillary thyroid carcinoma: a study integrating ultrasonographic features by Xia Zhang, Jie Li, Ming Gao, Yan Zhang

“…Further studies evaluating EpCAM expression in fine-needle aspiration biopsy (FNAB) samples are required to determine its possible preoperative predictive value.…”
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Emergent Anthropometric Indices in Differential Prediction of Prehypertension and Hypertension in Mexican Population: Results according to Age and Sex by Oscar Zaragoza-García, Ilse Adriana Gutiérrez-Pérez, Pedro Delgado-Floody, Isela Parra-Rojas, Daniel Jerez-Mayorga, Christian Campos-Jara, Iris Paola Guzmán-Guzmán

“…Logistic regression models and receiver operating characteristics curve analyses were used to assess the association and the predictive value of several emergent anthropometric indices with the presence of preHTN and HTN. …”
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Ureteral wall thickness at the ureterovesical junction as a significant factor in predicting medical expulsive therapy of ureterovesical junction stones by Tiancan Yang, Jian Ji, Yafei Wang, Xiaowen Gao, Lingmin Lei, Lvyang Chen, Shicheng Fan, Zhida Wu, Wei Pu, Yunbo Shang

“…Conclusions The UWT at the UVJ has a high predictive value for the MET of stones at this position, thus avoiding the adverse consequences of delayed stone discharge caused by unnecessary surgical operation and MET.…”
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Accuracy and reliability of non-invasive pressure-strain loop for myocardial work assessment in functional single ventricle patients by Mengqian Liao, Xuechen Liu, Junxiang Pan, Tianhao Liao, Xuan Li, Zonghui Hou, Jian Cui, Lianyi Wang

“…PSL parameters exhibited good intra- and inter-observer reproducibility and high predictive value for VEDP > 10 mmHg. Conclusions Pressure-strain loop indices can effectively evaluate cardiac function in FSV patients and reveal functional differences between subtypes. …”
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Scalp dosimetry as a predictor of radiation-induced alopecia in primary brain tumours: a retrospective study from a tertiary cancer centre in south India by Lalitha Nageshwari S, Govardhan HB, Ibrahim Khaleel, Vijayath BR, Akshay KT, Priyadarshini T, Sahana R

“…ROC statistical analysis was performed to evaluate the predictive value of scalp dosimetric parameters for RIA severity. …”
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Levels and clinical significance of serum Hcy，PTH and β2⁃MG in maintenance hemodialysis patients with chronic renal failure by LI Min，ZHANG Yuqin，ZHANG Hongxu

“…Receiver operating characteristic（ROC） curves were plotted to evaluate the predictive value of laboratory indicators for patient prognosis.…”
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Association of cardiometabolic markers with hepatic steatosis and liver fibrosis in population without obesity and diabetes by Zhixing Fan, Chaojun Yang, Xiaojing Zhao, Jing Zhang

“…The AUC values of these four cardiac markers were greater than FLI, among which eGDR showed the highest predictive value (AUC = 0.781). In the hepatic steatosis population, CMI (OR = 1.419, 95%CI: 1.033, 2.747), AIP (OR = 5.527, 95%CI: 1.082, 28.242), and TyG (OR = 2.345, 95%CI: 1.180, 4.661) were also showed significant association with liver fibrosis, while eGDR and FIB-4 were not associated with liver fibrosis. …”
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Relationship between neutrophil-to-lymphocyte ratio and pulmonary arterial hypertension in non-dialytic patients with chronic kidney disease stage 5 by 冯世尧, 任伟

“…Objective To investigate the clinical value of neutrophil-to-lymphocyte ratio(NLR)for pulmonary arterial hypertension(PAH)in non-dialytic patients with chronic kidney disease(CKD) stage 5.Methods A total of 144 non-dialysis patients with CKD stage 5 were divided into two groups:PAH group and non-PAH group according to pulmonary artery systolic pressure.Clinical data were compared between the two groups,Spearman correlation analysis was used to analyze the relationship between pulmonary artery systolic pressure and various factors.Binary classification Logistic regression analysis was applied to analyze the risk factors of PAH.Receiver operating characteristic(ROC)curve was adopted to evaluate the predictive value of NLR for PAH.Results There were 64 cases(44.4%)in the PAH group and 80 cases(55.6%)in the non-PAH group.NLR,platelet to lymphocyte ratio,left internal atrial diameter and main pulmonary internal artery diameter in the PAH group were significantly higher than those in the non-PAH group(P<0.05).Lymphocyte count,hemoglobin,serum iron,triglyceride,very low density lipoprotein cholesterol and left ventricular ejection fraction in the PAH group were significantly lower than those in the non-PAH group,with all statistically significant differences(P<0.05).NLR,left atrial diameter and main pulmonary artery diameter were positively correlated with pulmonary artery systolic pressure(P<0.05).Multivariate Logistic analysis showed that,NLR(OR=2.151,95%CI 1.438～3.218,P<0.001),left atrial diameter(OR=1.176,95%CI 1.068～1.294,P<0.05)and main pulmonary artery diameter(OR=1.229,95%CI 1.004～1.504,P<0.05)were independent risk factors for PAH.The results of ROC curve analysis showed that the area under curve of PAH predicted from NLR was 0.711(95% CI 0.626～0.797,P<0.05).When the NLR cutoff value was 3.23,the sensitivity and specificity for predicting the occurrence of PAH in non-dialysis patients with CKD stage 5 were 60.9% and 72.5%,respectively.Conclusions NLR has a good clinical value in predicting the occurrence of PAH in non-dialysis patients with CKD stage 5.Left atrial enlargement and main pulmonary artery enlargement were related to PAH.…”
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Association between sinusitis and incident rheumatic diseases: a population-based study by Ali Duarte-García, Kenneth J Warrington, Ashima Makol, Elena Myasoedova, Cynthia S Crowson, Jeffrey A Sparks, John M Davis, Vanessa L Kronzer, Andrew C Hanson, Robert Vassallo, Mattew J Koster, Alicia M Hinze, Kerry Wright

“…The primary exposure was presence of sinusitis, ascertained by diagnosis codes (positive predictive value 96%). We fit logistic regression models to estimate ORs for incident rheumatic diseases and disease groups, adjusted for confounders.Results We identified 1427 incident rheumatic disease cases and 4281 matched controls (mean age 63, 67% women, median 14 years electronic health record history). …”
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The impact of lacrimal gland characteristics on the clinical presentation of lacrimal gland prolapse in candidates for upper eyelid blepharoplasty by Bahram Eshraghi, Nahid Mirzaei, Samira Chaibakhsh, Ali Aghajani

“…The supine test demonstrated a 90% positive predictive value for LGP. Analysis of the prolapsed lacrimal gland characteristics indicated that the average length in patients with upright prolapse was significantly larger (8.33 ± 3.12 mm) than in those without (6.03 ± 2.91 mm, p = 0.001). …”
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A ROLE OF SUPEROXIDE DISMUTASE IN DEVELOPMENT OF POST-OPERATION ATRIAL FIBRILLATION IN CORONARY HEART DISEASE PATIENTS by O. A. Rubanenko, O. V. Fatenkov, S. M. Khokhlunov, L. V. Limareva

“…Patients with PSAF had III functional class of angina (72,4% vs 47,8%, р=0,028) and III functional class of congestive  heart failure (38,0% vs 7,5%, р=0,006), they had larger left atrium (43,5±4,1 mm vs 37,9±3,4 mm, р&lt;0,001).After multifactorial analysis, predictive value remained  for the following: left atrium larger than 41 mm — 5,1 (95% CI, 2,1-9,8, р=0,0005), SOD more than 2948 U/g — 4,4 (95% CI, 1,1-8,9, р=0,04).Conclusion. …”
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Life’s Crucial 9 score and chronic kidney disease: insights from NHANES 2005–2018 and the mediating role of systemic inflammation and oxidative stress by Shiyuan Qin, Jin Yang, Zili Wang, Pinglin He, Taotao Dong, Zhengyun Ren, Qiuyang Li

“…This study aimed to investigate the association between LC9 and CKD, compare its predictive value with LE8, and explore potential mediating mechanisms.MethodsThis study analyzed data from 16,431 participants in the National Health and Nutrition Examination Survey (NHANES) 2005–2018. …”
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Prediction of lymph node metastasis in lung adenocarcinoma using a PET/CT radiomics-based ensemble learning model and its pathological basis by Shulin Li, Shulin Li, Fang Chen, Lei Wang, Lei Wang, Zhiming Xiang

“…The purpose of this study is to explore the predictive value of the stacking ensemble learning model based on 18F-FDG PET/CT radiomic features and clinical risk factors for LNM in lung adenocarcinoma, and elucidate the biological basis of predictive features through pathological analysis.MethodsNinety patients diagnosed with lung adenocarcinoma who underwent PET/CT were retrospectively analyzed and randomly divided into the training and testing sets in a 7:3 ratio. …”
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The relationship between coping styles and the utilization and misuse of industrial and traditional substances in psychiatric patients: a cross-sectional study from Iran by Reza Moshfeghinia, Sara Shirvani, Mohammadsadegh Kamran, Kasra Assadian, Arvin Hedayati, Arash Mani

“…These findings underscore the predictive value of coping styles in addiction vulnerability and support the development of coping-focused interventions.…”
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Genome‐wide screening of abberant methylated drivers combined with relative risk loci in bladder cancer by Chuanjie Zhang, Kangjie Shen, Yuxiao Zheng, Feng Qi, Jun Luo

“…In the validation group from GSE13507, 17 hub genes remained higher predictive value with AUC = 0.723 and patients in high‐risk group. …”
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Complete blood count (CBC)-derived indices at admission and short-term outcomes in ICU patients: a retrospective study by Ravi Shukla, Vinutha Silvanus, Sagar Dahal, Prasamsha Sitaula, Zenish Niraula, Chandan Kumar Gupta, Kiran Lamichhane

“…While TLC alone did not differ significantly between survivors and non-survivors.Conclusion Among CBC-derived parameters, the neutrophil-to-lymphocyte ratio had some predictive value for all-cause in-ICU mortality. Further research among etiology or diagnosis-specific cohorts of ICU patients that demonstrate dynamic changes in CBC-derived parameters may be needed to elucidate their role in patient outcomes.…”
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