Association of coagulation-related indicators with postoperative venous thromboembolism occurrence in patients with pituitary tumors by Yi Xiang, Ya Wu, Huan Liu, Zheng Chen, JinYu Pan

“…Abstract This study aimed to analyze risk factors for postoperative VTE in pituitary tumor resection patients, focusing on coagulation indicators and their predictive value. This study collected clinical data from 300 patients who underwent pituitary adenoma resection from January 2021 to August 2023 in the Department of Neurosurgery, the Second Clinical College of the Army Medical University, China. …”
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An erythrocyte vesicle protein exported by the malaria parasite promotes tubovesicular lipid import from the host cell surface. by Pamela A Tamez, Souvik Bhattacharjee, Christiaan van Ooij, N Luisa Hiller, Manuel Llinás, Bharath Balu, John H Adams, Kasturi Haldar

“…Here, we combined bioinformatics and genome-wide expression analyses with a new series of transgenic and cellular assays to show for the first time in malaria parasites that microarray read out from a chemical perturbation can have predictive value. We thereby identified and characterized an exported P. falciparum protein resident in a new vesicular compartment induced by the parasite in the erythrocyte. …”
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Serumanti-PLA2R antibody predicted treatment outcome in idiopathic membranous nephropathy by Zhang Xue-qin, Jiang Hong, Yang Shu-fen, Zhao Hong-juan, Lu Chen

“…Objective To explore the predictive value of serum phospholipase A2 receptor antibody in determining the efficacy of rituximab in the treatment of idiopathic membranous nephropathy（IMN）.Methods From August 1,2017 to May 31,2020,a total of 120 IMN patients received rituximab for the first time or during long-term follow-ups were included.According to the serum level of phospholipase A2 receptor antibody, they were divided into the groups of positive and negative.The relevant data were compared between two groups.The remission rate of each group was analyzed by Kaplan Meier method and the remission rate between groups compared by log-rank test.Cox univariate and multivariate risk regression models were employed for adjusting the influencing factors of efficacy.Results Among 87 patients with positive serum phospholipase A2 receptor antibody, 9.1% and 6.9% achieved partial and complete remission versus 27.3% and 24.2% in serum phospholipase A2 receptor antibody negative group.The partial and complete remission rates after treatment with rituximab were higher in pla2 R-Ab positive group than those in negative group（χ²=5.057,P=0.0245;χ²=7.506,P=0.0061）.Conclusion The efficacy of rituximab is poor in the treatment of idiopathic membranous nephropathy with positive serum phospholipase A2 receptor antibody.Serum phospholipase A2 receptor antibody is an efficacy predictor of rituximab in IMN patients.…”
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Evaluation of the Toxocell Latex Agglutination Test as Screening Test and Distribution of Toxoplasma Antibodies among Sexually Active People in Najaf City by Hayder M. Samaka, Abdullah O. Alhatami, Kareem G. Mohammed

“…Results: The sensitivity and specificity and positive predictive value (PPV) of DLA test ( in comparison to IgM ELISA assay) were 100%, 64% and 10%, respectively. …”
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Brain metabolic imaging-based model identifies cognitive stability in prodromal Alzheimer’s disease by Jarrad Perron, Carly Scramstad, Ji Hyun Ko

“…The model’s high positive predictive value in the prodromal test set makes it a practical means for selecting candidates for anti-amyloid therapy and trials.…”
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Routine Genetic Testing of Germline Breast Cancer Susceptibility ─ Challenges and Opportunities by Cornelia Leo, Kathrin Schwedler, Rosaria Condorelli, Nicole Bürki, Jens Huober, Khalil Zaman, Christian Kurzeder, Marcus Vetter

“…Information on germline BRCA (g*BRCA*) 1/2 pathogenic or likely pathogenic mutations has predictive value for response to platinating agents and poly(ADP-ribose) polymerase inhibitors (PARPi) and survival outcomes of breast cancer (BC) patients. …”
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Predicting Real-World Physical Activity in Multiple Sclerosis: An Integrated Approach Using Clinical, Sensor-Based, and Self-Reported Measures by Patrick G. Monaghan, Michael VanNostrand, Taylor N. Takla, Nora E. Fritz

“…This study evaluates the predictive value of combining sensor-derived clinical measures and participant-reported outcomes to better forecast prospective physical activity levels in individuals with MS. …”
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Accuracy of HLA-DQ genotyping in combination with IgA anti-tissue transglutaminase serology and a "scoring system" for the diagnosis of celiac disease in Turkish children by Murat Çakır, Maşallah Baran, Fahri Uçar, Ulaş Emre Akbulut, Neşe Kaklıkkaya, Şafak Ersöz

“…The sensitivity, specificity, positive (PPV) and negative predictive value (NPV), positive (PLR) and negative likelihood ratio (NLR) and accuracy of the test combining genotyping and tTG-IgA positivity and the simple scoring system for the diagnosis of CD were evaluated. …”
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Achieving Motor Development Milestones at the Age of Three Months May Determine, but Does Not Guarantee, Proper Further Development by Ewa Gajewska, Magdalena Sobieska, Elżbieta Kaczmarek, Aleksandra Suwalska, Barbara Steinborn

“…The paper aims to demonstrate the reliability, sensitivity, and predictive value of an original motor performance assessment tool in comparison with the neurological assessment at 3, 6, and 9 months. …”
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Personalized Organoid-Based Treatments in Older Patients with Cancer: A Registry Study in Progress by Pirmin Häuptle, Kirsten Mertz, Michèle Voegeli, Robert Rosenberg, Emanuel Burri, Svetozar Subotic, Anna Romanens, Anne Leuppi-Taegtmeyer, Christian Regenbrecht, Lena Wedeken, Marcus Vetter

“…Clinical trials have demonstrated a high predictive value and statistically significant correlation between the patient’s clinical response and tumor organoid response in different cancer types. …”
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The use of pancreatic ductal adenocarcinoma 2D and 3D models to evaluate NDV infection, replication and induced cell death by Marco Huberts, Elham Aida Farshadi, Daphne Groeneveld, Ron A. M. Fouchier, Bernadette G. van den Hoogen

“…Although 2D models have been valuable, 3-dimensional models such as spheroids and patient-derived organoids (PDOs) better recapitulate tumor characteristics and may have higher predictive value for oncolytic viro-immunotherapy. Evaluating monolayers, spheroids, and PDOs for their response to oncolytic viro-immunotherapy using Newcastle Disease Virus (NDV) as an example may improve understanding of how model choice impacts outcomes. …”
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Comparative evaluation of six phenotypic methods for detecting extended-spectrum beta-lactamase-producing Enterobacteriaceae by Rajkumar Manojkumar Singh, Huidrom Lokhendro Singh

“…The Vitek 2 showed a sensitivity and specificity of 91.8% and 97.24%, respectively, with a positive predictive value of 93.33%. The sensitivities of the conventional methods ranged from 83% to 94%. …”
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Unveiling the prognostic significance of RNA editing-related genes in colon cancer: evidence from bioinformatics and experiment by Zhengcong Deng, Xueqin Jin, Bingxue Liu, Hongyan Zhen, Xiang Wang

“…Conclusion We established a prognostic model based on five RERGs with strong predictive value. This model not only serves as a foundation for a novel prognostic tool but also facilitates the identification of potential drug candidates for treating COAD.…”
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Role of Magnetic Resonance Arthrography (MRA) in the Diagnosis of Shoulder Injuries by Prateek Awasthi, Abhishek Dwivedi, Satveer S. Choudhary

“…In comparison with the gold standard for arthroscopy, the sensitivity (Sn), positive predictive value (PPV), and diagnostic accuracy (DA) of MRA for diagnosing shoulder injuries were evaluated. …”
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Routine blood tests in early pregnancy: their development and value in the early diagnosis of gestational diabetes mellitus by Guo-Lin Liu, Ning-Zhi Zhang

“…It has been found that blood cell parameters, inflammatory factors, fat metabolism indices and liver enzyme metabolism markers have specific early predictive value for GDM. The application of these parameters combined with significant independent risk factors in the early prediction and early diagnosis of GDM will be of great value in the prevention and treatment of GDM and the prognosis of mothers and infants. …”
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PLASMA LEPTIN LEVELS IN METABOLIC SYNDROME PATIENTS WITH ISCHEMIC HEART DISEASE by O. M. Drapkina, R. N. Shepel, T. A. Deeva

“…To assess leptin level in blood serum of patients with metabolic syndrome (MS), including comorbidity with ischemic heart disease (IHD), to reveal possible predictive value of this marker for IHD development in MS. …”
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FETAL DISCORDANCY IN MONOCHORIONIC TWINS by L. G. Sichinava, O. B. Panina, K. G. Gamsakhurdiya

“…Objective: to investigate the predictive value of fetal weight discordance as a risk factor associated with adverse perinatal outcomes. …”
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Diagnostic utility of whole body Dixon MRI in multiple myeloma: A multi-reader study. by Timothy J P Bray, Saurabh Singh, Arash Latifoltojar, Kannan Rajesparan, Farzana Rahman, Priya Narayanan, Sahar Naaseri, Andre Lopes, Alan Bainbridge, Shonit Punwani, Margaret A Hall-Craggs

“…Lesion count, true positives, sensitivity, and positive predictive value were compared across the four Dixon image types.…”
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Evaluating climatic variability's impact on milk yield across climate zones: A machine learning-based comparative study of Switzerland and Thailand by Boonyarat Phadermrod, Varunya Attasena

“…This study systematically compares conventional and modern machine learning models for milk yield prediction and evaluates the influence of climatic variability in Switzerland (moderate climate) and Thailand (tropical climate) using the same analytical framework.Five models—linear regression, ridge regression, gradient boosting regression, AdaBoost, and LightGBM—are tested with various feature sets, including Day-in-Milk, individual and combined meteorological variables, and three lagged milk yield values to assess their predictive value. Model performance is further analyzed on sub-datasets stratified by breed and parity range to explore climate effects in more homogeneous groups.The results demonstrate that simple models perform comparably to complex ones, with gradient boosting regression consistently outperforming other boosting methods. …”
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How Cognitive Reserve Could Protect from Dementia? An Analysis of Everyday Activities and Social Behaviors During Lifespan by Francesca Morganti, Ilia Negri

“…Conclusions: The utilization of contemporary technologies, the possession of a driver’s license, and the maintenance of an active social network have been demonstrated to possess a high degree of predictive value with respect to cognitive reserve in the context of aging.…”
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