Predictive Significance of the Monocyte-to-High-Density Lipoprotein Cholesterol Ratio in Post-Percutaneous Coronary Intervention Contrast-Induced Nephropathy Among Patients with Co... by Lin A, Peng Y, Shao J, Chen L, Lin Y

“…The study used regression analyses to investigate the relationship between MHR and CIN rate and postoperative mortality, and demonstrated the cumulative incidence of postoperative fatal events in the three groups of patients by Kaplan-Meier curves, and also analyzed the predictive value of MHR and other inflammatory indicators on the risk of CIN by using receiver operating characteristic (ROC) curves.Results: Compared to Group 1, Groups 2 and 3 had a higher incidence of CIN, higher mortality, and longer hospital stays (P < 0.001). …”
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DDAH1 Promotes Cisplatin Chemoresistance in Patients with Locally Advanced Nasopharyngeal Carcinoma via the EGFR‐JAK2‐STAT3 Pathway by Jin‐Hao Yang, Li Yuan, Qiu‐Yan Chen, Kai‐Qi Lan, Liang‐Ji Li, Yu‐Chen Li, Xiao‐Yun Li, Xue‐Song Sun, Lin‐Quan Tang, Sai‐Lan Liu, Hai‐Qiang Mai

“…To explore the regulatory mechanism and biological function of DDAH1 in cisplatin chemoresistance, NPC cell lines are subjected to overexpression and knockdown of DDAH1 in vitro, with findings further corroborated by in vivo chemosensitivity assays. The predictive value of DDAH1 expression is evaluated for survival and resistance to cisplatin‐based IC in a cohort of 339 patients with LANPC. …”
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Association between various insulin resistance surrogates and gallstone disease based on national health and nutrition examination survey by Rui Gong, Yuchen Ding, Kaiqi Yang, Xiaodie Meng, Xiujing Sun

“…The present study was designed to investigate the correlation between these novel IR surrogates and the risk of developing GSD and to explore the index with the best predictive value. We conducted a cross-sectional analysis using data from the National Health and Nutrition Examination Survey 2017-March 2020. …”
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Bartonella endocarditis: a complex diagnosis of blood culture-negative endocarditis in an endemic region of Africa by Hans Prozesky, Colette Pienaar, Simon Poerstamper, Luke D Hunter, Philip G Herbst, Anton F Doubell, Jantjie J Taljaard, Jacques J Janson, Alfonso JK Pecoraro

“…None of the PCR-proven cases of Bartonella endocarditis had negative serology, which suggests that the test has a high negative predictive value. The current guideline diagnostic titre of ≥1:800 is assay dependent and is not generalisable to alternative, commercially available, assays. …”
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Development of the EPO-Score – a multivariable tool to predict adverse outcome in infants with perinatal asphyxia undergoing therapeutic hypothermia – a retrospective study by Adriana van der Donk, Maria Schleier, Alisa Bär, Linda Mulzer, Regina Trollmann, Stephanie Schuessler, Steven Hébert, Gregor Hanslik, Joachim Woelfle, Heiko Reutter, Patrick Morhart

“…Infants with a score of 14 or higher were classified as high-risk.ConclusionEPO-Score underlines the correlation between the severity of early multi-organ involvement and severe adverse outcome, demonstrating a high predictive value within our study population. Early identification of patients with severe adverse outcome is important for optimizing neurodevelopmental therapies and providing family support. …”
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Comparative study of triglyceride glucose index and coronary heart disease risk in middle aged and elderly Chinese and British populations by Wei Mi, Yi-Han Hao, Ming-Guan Wan, Jia-Le Zhang, Hao-Ming Huang, Chen-Ze Song, Qi-Jing He, Nai-Yuan Fan, Xue Yao, Cai-Yun Chen

“…This cross-national study investigates the association between TyG index and coronary heart disease(CHD) incidence in Chinese and British populations, aiming to quantify regional differences in CHD prevalence, and elucidate the TyG index’s predictive value for CHD pathogenesis across distinct demographic contexts. …”
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Prognostic significance of severe mitral annular calcification in aortic stenosis: implications for aortic valve replacement outcome by Valeria Pergola, Dan-Alexandru Cozac, Maria Teresa Savo, Saima Mushtaq, Raffaella Motta, Roberto Pedrinelli, Pasquale Perrone-Filardi, Gianfranco Sinagra, Morena De Amicis, Maria Vittoria Chiaruttini, Gabriele Cordoni, Giulia Lorenzoni, Giuseppe Tarantini, Gino Gerosa, Dario Gregori, Giorgio De Conti, Domenico Corrado, Gianluca Pontone

“…Multivariate Cox models evaluated the predictive value of severe MAC alongside other significant variables. …”
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Association of Soluble Immune Checkpoint Molecules PD1 and 4‐1BB With CTLA‐4Ig Treatment Response in Early Rheumatoid Arthritis by Tilia Selldén, Kristina Lend, Jon Lampa, Merete Lund Hetland, Mikkel Østergaard, Tillmann Uhlig, Dan Nordström, Kim Hørslev‐Petersen, Björn Gudbjörnsson, Gerdur Gröndal, Inger Gjertsson, Ronald vanVollenhoven, Cristina Maglio, Kerstin Andersson, Anna‐Karin Hultgård Ekwall, Anna‐Carin Lundell, Anna Rudin

“…Furthermore, baseline levels of sPD1 or s4‐1BB together with proportions of PD1+ T follicular helper (TFh) cells predicted treatment response to CTLA‐4Ig with MTX after 48 weeks, achieving 90% and 100% positive predictive value, respectively. Conclusion High plasma levels of sPD1 and s4‐1BB are associated with good response to CTLA‐4Ig with MTX therapy in patients with eRA. …”
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Prognostic Value and Correlation Between WT1 Overexpression and NPM1 Mutation in Patients with Acute Myeloblastic Leukemia by LL Girshova, IG Budaeva, EG Ovsyannikova, SO Kuzin, DV Motorin, RSh Badaev, DB Zammoeva, VV Ivanov, KV Bogdanov, OS Pisotskaya, YuV Mirolyubova, TS Nikulina, YuA Alekseeva, AYu Zaritskii

“…The research showed the predictive value of a lower limit level of WT1 on day 28 of treatment (100 per 104 copies ABL), and for the first time, the importance of the early assessment WT1 expression reduction on day 14 of induction therapy.…”
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The role of triglyceride-glucose index in the progression of cardiovascular-kidney-metabolic syndrome: findings from the China health and retirement longitudinal study by Xingyu Zhou, Xingyu Zhou, Yisi Liu, Yisi Liu, Yisi Liu, Yisi Liu, Jiafei Peng, Jiafei Peng, Jiafei Peng, Jiafei Peng, Xianliang Zhou, Hongtao Wei, Hongtao Wei, Hongtao Wei, Hongtao Wei

“…Q1: HR 2.21, 95% CI 1.58–3.08, P < 0.01) in stage 1.ConclusionElevated TyG index is a significant predictor of CKM progression, particularly via the development of metabolic abnormalities. Its predictive value varies across age groups and CKM stages. …”
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Multi-omics analysis uncovers predictive biomarkers for the efficacy and outcomes of chemoimmunotherapy in advanced unresectable biliary tract cancers by Jiaojiao Ni, Chaoqun Li, Xiaoqing Xu, Qi Xu, Qian Yin, Hanlin Chen, Shurui Zhou, Jingjing Li, Qinhong Zheng, Yanru Xie, Hongjun Hua, Jianying Jin, Tieming Xie, Haiping Zhao, Feng Yan, Junjun Shen, Yihui Huang, Wangye Zheng, Junrong Yan, Xiaoying Wu, Song Wang, Qiuxiang Ou, Yang Shao, Wei Wu, Wei Zhuo, Jieer Ying

“…The immune-modulatory effects of CXCL9/CTLA4 and their predictive value for treatment efficacy were further validated in a multicenter BTC cohort. …”
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Evaluation of the implementation of the EWARS Mobile epidemiological surveillance tool in Sudanese refugee camps in Eastern Chad: a retrospective and population-based surveillance... by Stephane Tewo, Balde Thierno, Freddy M. Banza, Idriss M. Mahamat, N'dri K. Eric-Didier, Djinguebey N. Raoul, John Otokoye Otshudiema, Castilla Echenique Jorge, Moussa Brahimi, Djoumbarina Maina, Evers Egmond, Marcel Woung, Kazuki Shimizu, Boris I. Pavlin, Jacques L. Tamuzi, Jacques L. Tamuzi, Patrick D. M. C. Katoto, Patrick D. M. C. Katoto, Patrick D. M. C. Katoto, Charles S. Wiysonge, Charles S. Wiysonge, Blanche-Philomene Melanga Anya

“…The sensitivity and positive predictive value were estimated at 81% (79%–83%) and 72.0% (68%–75%), respectively.ConclusionsThe EWARS Mobile is a practical solution for Eastern Chad provinces to implement throughout the pre-epidemic and outbreak periods in vulnerable children in this severe humanitarian crisis. …”
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Clinical value of the renal pathologic scoring system in complement-mediated thrombotic microangiopathy by Fei-Fei Chen, Xiao-Juan Yu, Hui Wang, Xu Zhang, Ying Tan, Zhen Qu, Su-Xia Wang, Feng Yu, Min Chen, Ming-Hui Zhao

“…Objectives This study was initiated to establish a renal thrombotic microangiopathy (TMA) scoring system based on clinical needs and investigate its predictive value for patients’ long-term outcomes.Methods Kidney biopsy-proven Complement-mediated TMA (C-TMA) patients from January 2000 to December 2017 in Peking University First Hospital were retrospectively studied. …”
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Short-term and long-term oncological outcomes of chemoradiotherapy for rectal cancer patients with or without oxaliplatin: a propensity score-matched retrospective analysis by Amirali Azimi, Fatemeh Sadat Tabatabaei, Kasra Kolahdouzan, Hamideh Rashidian, Forouzan Nourbakhsh, Maryam Abedini Parizi, Nima Mousavi Darzikolaee, Reyhaneh Bayani, Samaneh Salarvand, Azadeh Sharifian, Farzaneh Bagheri, Saeed Rezaei, Naeim Nabian, Reza Nazari, Negin Mohammadi, Mohammad Babaei, Marzieh Lashkari, Farshid Farhan, Mahdi Aghili, Felipe Couñago, Maria Antonietta Gambacorta, Reza Ghalehtaki

“…However, CAPEOX did not demonstrate any statistically significant predictive value for DFS (P = 0.500) or OS (P = 0.449). …”
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Prognostic significance of NT-proBNP and sST2 in patients with heart failure with preserved and mildly reduced ejection fraction by V. I. Podzolkov, N. A. Dragomiretskaya, A. V. Tolmacheva, I. I. Shvedov, A. A. Ivannikov, I. V. Akyol

“…At ROC analysis to one-year adverse events, both NT-proBNP and sST2 showed a significant predictive value in patients with EF >40% with an optimal cut-off value of 746 pg/ml (AUC 0.709; p = 0.005, sensitivity 62%, specificity 69%) and 27.1 ng/ml (AUC 0.742; p = 0.03, sensitivity 80%, specificity 75.8%) respectively.Conclusion: NT-proBNP levels >746 pg/ml and sST2 >27.1 ng/ml should be considered as predictors of poor prognosis in CHF patients with LVEF >40%.…”
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Postreperfusion Renal Allograft Biopsy Predicts Outcome of Single-Kidney Transplantation: A 10-Year Observational Study in China by Meifang Wang, Junhao Lv, Jie Zhao, Huiping Wang, Jianghua Chen, Jianyong Wu

“…We investigated the predictive value of postreperfusion biopsy on long-term allograft outcome after single-kidney transplantation. …”
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Prognostic impact of dynamic changes of type I melanoma antigen gene proteins CT7 (MAGE-C1/CT7) transcripts in multiple myeloma by Xuelin Dou, Fengrong Wang, Huan Chen, Yao Chen, Lei Wen, Yang Liu, Guorui Ruan, Xiaosu Zhao, Xiaojun Huang, Robert Peter Gale, Jin Lu, Jin Lu

“…Our data showed the predictive value of peri-ASCT frontline treatment. A 2-log decrease of MAGE-C1/CT7 post-induction cycle 2 compared to baseline correlated with a negative peri-ASCT MAGE-C1/CT7 status, providing an earlier prognostic marker of treatment response.…”
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Validation of the COAPT risk score in Polish patients undergoing transcatheter edge-to-edge repair of severe, functional mitral regurgitation: a multicenter, observational study by Karolina Jasińska-Gniadzik, Michał Łomiak, Jerzy Pręgowski, Zbigniew Chmielak, Piotr Kasprzyk, Jan Kasprzyk, Rafał Gałąska, Michał Chmielecki, Miłosz J. Jaguszewski, Marcin Fijałkowski, Aleksandra Topolska, Michał Sekuła, Marcin Grabowski, Janusz Kochman, Adam Rdzanek, Piotr Scislo, Agnieszka Kapłon-Cieślicka, Renata Główczyńska, Monika Budnik, Radosław Piątkowski, Łukasz Kołtowski, Arkadiusz Pietrasik, Aleksandra Gąsecka

“…CONCLUSIONS: In Polish patients fulfilling COAPT criteria, the COAPT risk score has moderate predictive value for post-procedural outcomes. In COAPT non-eligible patients, novel tools are required to predict outcomes.…”
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MULTISPIRAL COMPUTED TOMOGRAPHY VERSUS MYOCARDIAL BIOPSY IN DIAGNOSTICS OF YOCARDITIS AND PROGNOSIS EVALUATION OF DILATION CARDIOMYOPATHY SYNDROME by I. N. Alieva, O. V. Blagova, N. V. Gagarina, A. V. Nedostup, E. A. Kogan, V. P. Sedov, V. V. Kadochnikova, A. E. Donnikov, V. A. Zaydenov, A. G. Kupriyanova, S. K. Ternovoy

“…Sensitivity and specificity of all types of delayed accumulation in diagnostics of myocarditis were 63,3% and 78,7%, positive and negative predictive value 86,1% and 50,7%, subepicardial and transmural types — 49,0%, 83,0%, 85,7%, 43,8%, respectively. …”
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Stress hyperglycemia ratio as a biomarker for early mortality risk stratification in cardiovascular disease: a propensity-matched analysis by Mingxing Lei, Yan Li, Longcan Cheng, Nan Tang, Jie Song, Mi Song, QingQing Su, Mingxuan Liu, Shihui Fu, Feng Lin, Yuan Gao

“…The incremental predictive value of SHR support its utility for risk stratification, particularly for short-term outcomes, but its prognostic value fades for long-term mortalities. …”
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