Clinicopathologic and prognosis of 30 patients with FH-deficient renal cell carcinoma: a single-center retrospective study by Junjie Bai, Jianjia Huang, Yushi Ye, Jun Lin, Yahui Wen, Zicheng Cai, Peihuang Chen, Tong Shangguan, Gaoyu Zou, Qianyi Qiu, Ru Chen, Rong Liu, Weizhong Cai, Shaoxing Zhu, Jianhui Chen, Xiaoyan Li

“…Conclusion FH-RCC is highly aggressive and has a poor prognosis, and clinical and pathologic parameters such as IHC expression including PD-1, PD-L1, PD-L2 and CTLA-4 have a predictive value in prognosis and treatment.…”
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Value of C⁃reactive protein/albumin ratio，pancreatic stone protein combined with interleukin⁃12 on prediction of offline extubation outcomes of patients with mechanical ventilation... by HOU Hongmei，PENG Feng，XIAO Yun

“…Objective To explore the predictive value of the ratio of C ⁃ reactive protein to albumin（CRP/ALB），pancreatic stone protein（PSP），and interleukin⁃12（IL⁃12）for the outcome of offline extubation in patients withmechanical ventilation in severe pneumonia，in order to guide clinical decision⁃making and enhance weaning success rates. …”
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A Multicenter Retrospective Study Predicting Early Noninvasive Ventilation Failure in Patients With Acute Hypoxic Respiratory Failure by Xiaoyi Liu, Hui Liu, Lijuan Chen, Xiangde Zheng, Hui Ran, Lili Chen, Rui Zhou, Yufeng Wang

“…ABSTRACT Background Volume OXygenation (VOX) index has good efficacy in predicting the failure of high‐flow nasal cannula therapy. However, its predictive value for treatment failure in patients receiving noninvasive ventilation (NIV) remains uncertain. …”
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GPD1L as a potential biomarker associated with Treg cell infiltration and lipid metabolism in clear cell renal cell carcinoma by Ming Yang, Dejiang Pang, Chuhui Gong, Kangping Song, Hongbo Ma, Yu Yang, Shujin Guo, Liqiong Wang

“…The expression of GPD1L in ccRCC cell lines and tissue samples was verified by western blotting, real time qPCR and immunohistochemistry. The predictive value of GPD1L was evaluated by survival analysis, ROC curve and Cox regression analysis. …”
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Radiomic-based models are able to predict the pathologic response to different neoadjuvant chemotherapy regimens in patients with gastric and gastroesophageal cancer: a cohort stud... by Annamaria Agnes, Luca Boldrini, Federica Perillo, Huong Elena Tran, Maria Gabriella Brizi, Riccardo Ricci, Jacopo Lenkowicz, Claudio Votta, Alberto Biondi, Riccardo Manfredi, Vincenzo Valentini, Domenico M. D’Ugo, Roberto Persiani

“…Radiomic models (in the entire case series and according to NAC regimens) were evaluated using the receiver operating characteristic area under the curve (AUC), sensitivity, and negative predictive value (NPV). Results The study included 77 patients undergoing NAC and subsequent tumor resection. …”
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Relationship between quantitative parameters of contrast⁃enhanced ultrasound and EMT⁃related markers and prognosis in patients with liver metastasis of colorectal cancer by CHEN Xi*，SUN Gaixia，WANG Likun，WU Xueliang

“…<b>Objective</b> To investigate the relationship between quantitative analysis of contrast-enhanced ultrasound（CEUS） and epithelial mesenchymal transition（EMT） related markers in patients with colorectal cancer liver metastasis（CRLM），and the predictive value of CEUS for the prognosis of patients. …”
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Membrane transporter genes predict chemoradiotherapy response in patients with cervical cancer by Natália Gregório Custódio, Fábio Ribeiro Queiroz, Angelo Borges de Melo Neto, Brenda Martins Cavalcante, Laurence Rodrigues do Amaral, Telma Maria Rossi de Figueiredo Franco, Matheus de Souza Gomes, Vasco Ariston de Carvalho Azevedo, Letícia da Conceição Braga, Paulo Guilherme de Oliveira Salles, Wander de Jesus Jeremias

“…Conclusion: Our results strongly suggest the presence of a candidate gene signature comprising ATP1B3 and SLCO1B3 that holds predictive value for chemoradiotherapy response in cervical cancer.…”
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Predictive Models Using Machine Learning to Identify Fetal Growth Restriction in Patients With Preeclampsia: Development and Evaluation Study by Qing Hua, Fengchun Yang, Yadan Zhou, Fenglian Shi, Xiaoyan You, Jing Guo, Li Li

“…ML models were constructed to evaluate the predictive value of maternal parameter changes on preeclampsia combined with FGR. …”
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Using the ORACLE Risk Score to Assess Hemorrhagic Risk in Patients with Acute Coronary Syndrome and Atrial Fibrillation by V. A. Brazhnik, L. O. Minushkina, A. D. Erlikh, E. D. Kosmacheva, M. A. Chichkova, N. R. Khasanov, D. A. Zateyshchikov

“…The ORACLE risk score had the greatest prognostic value (area under the ROC curve 0.874±0.0416, sensitivity 82.7%, specificity 79.1%). The predictive value of the HAS-BLED risk score was slightly lower (area under the ROC curve 0.710±0.0360, sensitivity 63.2%, specificity 56.8%). …”
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Association between different dimensions of the C-reactive protein-triglyceride-glucose index and future cardiovascular disease risk in individuals with cardiovascular-kidney-metab... by Jintao Chen, Liying Yan, Lei He, Weixue Wang

“…Longitudinal monitoring of CTI changes over time can help early identification of high CVD risk in this population, and its predictive value is significantly superior to that of the TyG index. …”
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Detection of urinary levels of matrix metalloproteinase-7 and tumor necrosis factor-like weak inducer of apoptosis in patients with IgA nephropathy and values in predicting disease... by Ma Yong-duo, Wang Cong, Li Hai-xiang, Wu Huan

“…ObjectiveTo explore the expressions of urinary matrix metalloproteinase-7 （MMP-7） and tumor necrosis factor-like weak inducer of apoptosis （TWEAK） in patients with IgA nephropathy （IgAN） and examine its predictive value.MethodsFrom January 2018 to March 2021，115 IgAN patients and 50 normal subjects （control group） were selected.Based upon the progress of IgAN，115 cases of IgAN patients were divided into two groups of IgAN progressive （<italic>n</italic>=42） and IgAN non-progressive （<italic>n</italic>=73）.According to the IgAN Oxford classification criteria，they were assigned into two groups of MEST-C≥3 （<italic>n</italic>=45） and MEST-C&lt;3 （<italic>n</italic>=70）.The levels of urinary MMP-7 and TWEAK were compared between two groups.Multivariate Logistic regression was utilized for analyzing the risk factors of IgAN progression.Receiver operating characteristic （ROC） curve was plotted for examining the values of urinary MMP-7 and TWEAK levels in predicting IgAN progression.ResultsThe levels of urinary MMP-7 （15.72±7.85 <italic>vs</italic> 6.92±0.53 ng/mL） and TWEAK were significantly higher in IgAN progressive group than those in IgAN non-progressive group ［（958.47±42.60） <italic>vs</italic> （206.73±15.18）ng/mL，<italic>P</italic>&lt;0.001］.The levels of urinary MMP-7 ［（23.92±9.27） <italic>vs</italic> （18.15±8.36） ng/mL］ and TWEAK ［（1408.70±71.15） <italic>vs</italic> （1036.28±50.72） ng/mL］ were significantly higher in MEST-C≥3 score group than those in MEST-C&lt;3 score group （<italic>P</italic>&lt;0.001）.Multivariate Logistic regression analysis indicated that elevated levels of MMP-7 ［<italic>OR</italic>=2.986 95%<italic>CI</italic>（2.146，-8.513）］ and TWEAK ［<italic>OR</italic>=3.370 95%<italic>CI</italic>（2.752，-10.118）］ were the risk factors affecting the progression of IgAN.Receiver operating characteristic （ROC） curve indicated that the area under the curve （AUC） of MMP-7 and TWEAK in predicting IgAN progression was 0.948 （95% <italic>CI </italic>0.885-0.997） with a sensitivity of 97.5% and a specificity of 85.0%.Correlation analysis indicated that the urinary levels of MMP-7 and TWEAK were significantly positively correlated with M，E，S and T （<italic>P</italic>&lt;0.001）.ConclusionThe elevated urinary levels of MMP-7 and TWEAK are the risk factors affecting the progression of IgAN.Both may be used as biological indicators for predicting the progression of IgAN.…”
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Prognostic value of the HFA-PEFF and H(2) FPEF scores for clinical outcomes in patients with coronary artery disease and preserved ejection fraction by Xuefeng Wu, Jianming Li, Zhaoyan Xu, Yingqing Feng

“…Cox proportional hazards regression was applied to assess the independent predictive value of the HFA-PEFF and H2FPEF scores for adverse outcomes. …”
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PREDICTIVE RELEVANCE OF DIFFERENT CLINICAL AND LABORATORY FINDINGS FOR HIGHER MORTALITY IN PATIENTS WITH COVID-19 IN A SINGLE CENTER COHORT: NEUTROPHIL/ LYMPHOCYTE RATIO, HIGH CR... by Oğuz Evlice, Fatih Kuş, Özlem Arık, Murat Bektaş

“…Therefore, we aimed to evaluate the predictive value of different clinical and laboratory parameters in disease severity and mortality in patients with COVID-19. …”
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Evaluative performance of TyG-ABSI versus traditional indices in relation to cardiovascular disease and mortality: evidence from the U.S. NHANES by Xin Zheng, Wenjing Zhang, Feng Yang, Leigang Wang, Bing Yu, Bin Liang

“…This study aims to explore the association between TyG-ABSI and cardiovascular events in individuals with MetS and compare its predictive value with the traditional TyG index in this specific population. …”
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Aneuploidy screening in women of advanced age in the public healthcare setting of a low- to middle- income country – an observational cohort study by L Geerts, N Du Toit, M Schoeman

“…In the SA public sector, DS screening and confirmatory genetic testing are fully state subsidised for women of advanced maternal age (AMA) but, owing to the low positive predictive value of AMA-based screening, ultrasound-based screening is also offered. …”
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Association between albumin and short-term outcomes of unplanned early readmission emergency department patients: A retrospective cohort study. by Liang Zhou, Xiaona Cai, Kunpeng Hu, Shuo Tang, Dandan Gao, Xiaojuan Zhang, Yin Wu, Li He, Bangfu Zhou, Ruoyu Wu, Zhigang Zhang

“…The purpose of this study was to analyze the predictive value of albumin for the short-term survival of patients with unplanned early readmission to the emergency department (ED).…”
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Dynamic serum lactate dehydrogenase monitoring during the acute phase and association with in-hospital all-cause mortality risk in large vessel occlusion acute ischemic stroke pati... by Weiwei Gao, Lijuan Cai, Xingyu Chen, Renjing Zhu

“…However, the dynamic changes and predictive value of serum LDH during the acute phase in patients with large vessel occlusion acute ischemic stroke (LVO-AIS) remain insufficiently characterized. …”
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Impact of the Triglyceride–Glucose index on all-cause and cardiovascular mortalities across different metabolic health and obesity statuses in US adults by Tao Yi, Zi Lin, Feng Hu, Jinhua Chen, Lianglong Chen

“…This finding indicates that the predictive value of the TyG index for mortality differs across populations, highlighting the necessity of accounting for metabolic status when the TyG index is used for prognostic evaluation.…”
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Prognostic effect of body roundness index on all-cause mortality among US older adults by Yiling Yang, Xiaomin Shi, Xiaohong Wang, Shu Huang, Jia Xu, Chen Xin, Ziyan Li, Yizhou Wang, Yusong Ye, Sha Liu, Wei Zhang, Muhan Lv, Xiaowei Tang

“…This NHANES-based study highlights the U-shaped relationship between BRI and all-cause mortality among U.S. older adults, suggesting that the BRI has predictive value for mortality outcomes. The findings offer compelling support for utilizing BRI as a non-invasive mortality risk screening tool.…”
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Functional Imaging of Liver Cancer (FLIC): Study protocol of a phase 2 trial of 18F-DCFPyL PET/CT imaging for patients with hepatocellular carcinoma. by Esther Mena, Joanna Shih, Joon-Yong Chung, Jennifer Jones, Atoosa Rabiee, Cecilia Monge, Baris Turkbey, Liza Lindenberg, Kilian E Salerno, Michael Kassin, Brad Wood, Jonathan Hernandez, Roberto Maass-Moreno, Babak Saboury, Neha Jakhete, Jason K Molitoris, Keith R Unger, Peter L Choyke, Freddy E Escorcia

“…The primary endpoint is the positive predictive value of 18F-DCFPyL-PET for HCC as confirmed by histopathology. …”
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