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Predictive value of the maternal alpha-fetoprotein variant, L2, during the first trimester of pregnancy screening for fetal trisomy 21, trisomy 18, and neural tube defects
Published 2025-08-01“…For predicting trisomy 18, the positive predictive value of AFP-L2 was somewhat lower than PAPP-A. …”
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Predictive value of early MoCA score combined with serum S100 protein and 25⁃hydroxyvitamin D3 levels on secondary cognitive dysfunction in patients with cerebral infarction
Published 2025-08-01“…Objective To explore the early Montreal Cognitive Assessment（MoCA）score and serum levels of S100 protein and 25 ⁃ hydroxyvitamin D3［25（OH）D3］in patients with cerebral infarction who had secondary cognitive dysfunction，and to analyze the predictive value of these three factors for secondary cognitive dysfunction in patients with cerebral infarction. …”
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Risk factors for hypocalcemia after total thyroidectomy: a narrative review
Published 2025-08-01Subjects: Get full text
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The predictive value of triglyceride glucose-body mass index for contrast-induced nephropathy in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention
Published 2025-07-01“…ROC curve analysis showed that TyG-BMI had a high predictive value for CIN (AUC = 0.812; 95%CI 0.784–0.840), the best cut-off value was 196.34, the sensitivity was 85.6%, and the specificity was 73.1%. …”
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The Relationship Between Serum SFRP5, ApoA‐I, HDL3‐C Level and In‐Stent Restenosis After PCI in Acute Myocardial Infarction and the Combined Predictive Value
Published 2025-05-01“…The receiver operating characteristic (ROC) curve was drawn to analyze the predictive value of SFRP5, ApoA‐I, and HDL3‐C in ISR after PCI. …”
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The predictive value of mean platelet volume to platelet count ratio combined with APACHEⅡs for short-term prognosis of patients with acute kidney injury treated by continuous renal replacement therapy
Published 2020-01-01“…Objective To investigate the predictive value of mean platelet volume(MPV)to platelet count(PLT)ratio(MPR)combined with acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)scoring for the short-term prognosis of patients with acute renal injury(AKI)treated with continuous renal replacement therapy(CRRT).Methods A total of 138 AKI patients who received CRRT in our hospital from January 2016 to October 2019 were retrospectively included.According to their survival conditions at discharge,they were divided into survival group(n=80)and death group(n=58).The value of MPR,APACHE Ⅱ score and their combination for predicting the death of AKI patients was analyzed by ROC curve.The independent risk factors for poor prognosis were evaluated by multivariate logistic regression analysis.Results(1)MPV,MPR and APACHE Ⅱ scores of patients in the death group were significantly higher than those in the survival group[(11.9±1.1)fl vs.(11.0±1.1)fl,P<0.01;0.11(0.09,0.14)vs.0.08(0.06,0.11),P<0.01;(25.0±3.5)score vs.(19.5±3.4)score,P<0.01].PLT count of patients in death group was significantly lower than that of survival group[(108.9±28.0)×10~9/L vs.(146.8±41.4)×10~9/L,P<0.01].(2)The cutoff values of MPR,APACHE Ⅱ score and the combination to predict the death of AKI patients were 0.08,24 points and 0.54,respectively.The AUC of death in AKI patients predicted by MPR combined with APACHE Ⅱ was significantly higher than that of MPR and APACHE Ⅱ alone[0.892(0.828-0.938)vs.0.737(0.656-0.809),P<0.01;0.892(0.828-0.938)vs.0.838(0.766-0.896),P<0.05].(3)APACHE Ⅱ score(≥24),MPR combined with APACHE Ⅱ score(APACHE Ⅱ score≥24,and MPR≥0.08),diuretics administration were the independent risk factors for poor prognosis in AKI patients[HR(95%CI):2.311(1.034-5.166),3.533(1.541-8.098),34.816(7.475-162.149),all P< 0.05].Conclusions MPR combined with APACHE Ⅱ score can well predict the short-term prognosis of AKI patients treated with CRRT.…”
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Predictive value of the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) for all-cause and cardiovascular mortality with non-hyperhomocysteinemia: evidence from NHANES 1999 to 2006
Published 2025-05-01“…Lastly, the NHHR's predictive value for mortality as well as its potential mediating effects were evaluated.ResultsA total of 13,847 participants were included in our study. …”
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Machine learning based metabolomic and genetic profiles for predicting multiple brain phenotypes
Published 2024-12-01Subjects: Get full text
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Relationship between intact parathyroid hormone，fetal globulin A，serum creatinine/hemoglobin ratio and disorder of calcium and phosphorus metabolism in maintenance hemodialysis patients with chronic kidney disease and their predictive values for carotid artery calcification
Published 2022-04-01“…ObjectiveTo explore the relationship between intact parathyroid hormone （iPTH），fetal globulin A （FA），serum creatinine/hemoglobin ratio （Scr/Hb） and calcium and phosphorus metabolism disorder in chronic renal failure patients with chronic kidney disease （CKD） on maintenance hemodialysis （MHD） and examine the predictive value of each parameter for carotid atherosclerosis.MethodsFrom July 2014 to July 2020，113 CKD patients on MHD were recruited and divided into two groups of sclerosis （<italic>n</italic>=30） and non-sclerosis （<italic>n</italic>=83）.The baseline levels of iPTH，FA and Scr/Hb of two groups were recorded.The related influencing factors of carotid atherosclerosis，parameters of calcium and phosphorus metabolism and their correlations were examined.ResultsBaseline phosphorus，iPTH and Scr/Hb in sclerosis group were higher than those in non-sclerosis group ［（1.89±0.42）mmol/L、305.26（152.63，608.19）μg/L、7.16±2.19 <italic>vs </italic>（1.30±0.36）mmol/L、238.47（118.05，506.11）μg/L、4.38±1.38，<italic>P</italic><0.001］，FA was lower than that of non-sclerosis group ［（74.62±20.61）mg/L <italic>vs </italic>（95.33±25.80）mg/L，<italic>P</italic><0.05］； mean values of iPTH，FA and Scr/Hb were selected as boundary，<mean value was low level，≥ mean value high level.High levels of iPTH and Scr/Hb were higher than those with low levels ［（1.60±0.39）mmol/L <italic>vs </italic>（1.18±0.33）mmol/L，（1.71±0.55）mmol/L <italic>vs </italic>（0.97±0.31）mmol/L］ and those with high levels of FA lower than those with low levels ［（1.25±0.34）mmol/L <italic>vs </italic>（1.72±0.40）mmol/L，<italic>P</italic><0.05］； iPTH，Scr/Hb and phosphorus were positively correlated while FA was negatively correlated with phosphorus （<italic>P</italic><0.05）；iPTH，FA，Scr/Hb were still associated with IMT （<italic>P</italic><0.05）； the area under the curve （AUC） of iPTH，FA and Scr/Hb for predicting carotid atherosclerosis were 0.742，0.776 and 0.790 respectively.It was the largest at 0.918 for combined predicting.The optimal predictive sensitivity and specificity were 93.33% and 85.54% respectively.ConclusioniPTH，FA and Scr/Hb are closely correlated with disorder of calcium and phosphorus metabolism in chronic renal failure patients with CKD on MHD.These parameters offer high application values in predicting carotid atherosclerosis.…”
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Performance and clinical implications of non-invasive prenatal testing for rare chromosomal abnormalities: a retrospective study of 94,125 cases
Published 2025-08-01Subjects: Get full text
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Optimization of the prognosis of postoperative complications in patients with breast cancer
Published 2025-04-01Subjects: Get full text
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