Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children. by Ezio Bonifacio, Andreas Beyerlein, Markus Hippich, Christiane Winkler, Kendra Vehik, Michael N Weedon, Michael Laimighofer, Andrew T Hattersley, Jan Krumsiek, Brigitte I Frohnert, Andrea K Steck, William A Hagopian, Jeffrey P Krischer, Åke Lernmark, Marian J Rewers, Jin-Xiong She, Jorma Toppari, Beena Akolkar, Richard A Oram, Stephen S Rich, Anette-G Ziegler, TEDDY Study Group

“…The risk (positive predictive value) for developing multiple islet autoantibodies (pre-symptomatic type 1 diabetes) and type 1 diabetes was determined in 4,543 children who had no first-degree relatives with type 1 diabetes and either a heterozygous HLA DR3 and DR4-DQ8 risk genotype or a homozygous DR4-DQ8 genotype, and in 3,498 of these children in whom genetic scores were calculated from 41 single nucleotide polymorphisms. …”
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Diagnostic accuracy of CADe-assisted reading versus clinician reading for polyp detection in colon capsule endoscopy: a multicentre prospective study by Ian Io Lei, Nicolas Parsons, Cristiana Huhulea, Hagen Wenzek, Elizabeth White, Pablo Laiz, Charlie Noble, Alexander Robertson, Anastasios Koulaouzidis, Ramesh Arasaradnam

“…The per-polyp sub-analysis evaluated 1,803 polyps, examining sensitivity, positive predictive value and the impact of different factors on AI-assisted accuracy performance. …”
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Predictive Significance of the Monocyte-to-High-Density Lipoprotein Cholesterol Ratio in Post-Percutaneous Coronary Intervention Contrast-Induced Nephropathy Among Patients with Co... by Lin A, Peng Y, Shao J, Chen L, Lin Y

“…The study used regression analyses to investigate the relationship between MHR and CIN rate and postoperative mortality, and demonstrated the cumulative incidence of postoperative fatal events in the three groups of patients by Kaplan-Meier curves, and also analyzed the predictive value of MHR and other inflammatory indicators on the risk of CIN by using receiver operating characteristic (ROC) curves.Results: Compared to Group 1, Groups 2 and 3 had a higher incidence of CIN, higher mortality, and longer hospital stays (P < 0.001). …”
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Association between various insulin resistance surrogates and gallstone disease based on national health and nutrition examination survey by Rui Gong, Yuchen Ding, Kaiqi Yang, Xiaodie Meng, Xiujing Sun

“…The present study was designed to investigate the correlation between these novel IR surrogates and the risk of developing GSD and to explore the index with the best predictive value. We conducted a cross-sectional analysis using data from the National Health and Nutrition Examination Survey 2017-March 2020. …”
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Shifting epidemic trends and severity in pediatric Mycoplasma pneumoniae infections in the post-COVID-19 era by Zongming Yang, Rui Shi, Xiuyun Zhou, Dong Xu, Wankai Xue, Wenjing Zhang, Xiaopei Cao, Jing Peng, Xiaoping Luo, Yongjian Huang

“…The post-intervention MP resurgence peaked later, with an average monthly positivity rate significantly exceeding predicted values (18.77% vs. 10.87%; PR = 1.69, 95% CI: 1.33, 2.16). …”
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Bartonella endocarditis: a complex diagnosis of blood culture-negative endocarditis in an endemic region of Africa by Hans Prozesky, Colette Pienaar, Simon Poerstamper, Luke D Hunter, Philip G Herbst, Anton F Doubell, Jantjie J Taljaard, Jacques J Janson, Alfonso JK Pecoraro

“…None of the PCR-proven cases of Bartonella endocarditis had negative serology, which suggests that the test has a high negative predictive value. The current guideline diagnostic titre of ≥1:800 is assay dependent and is not generalisable to alternative, commercially available, assays. …”
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Comparative study of triglyceride glucose index and coronary heart disease risk in middle aged and elderly Chinese and British populations by Wei Mi, Yi-Han Hao, Ming-Guan Wan, Jia-Le Zhang, Hao-Ming Huang, Chen-Ze Song, Qi-Jing He, Nai-Yuan Fan, Xue Yao, Cai-Yun Chen

“…This cross-national study investigates the association between TyG index and coronary heart disease(CHD) incidence in Chinese and British populations, aiming to quantify regional differences in CHD prevalence, and elucidate the TyG index’s predictive value for CHD pathogenesis across distinct demographic contexts. …”
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Prevalence of cardiovascular diseases and risk factor assessment in breast cancer survivors exposed to cardiotoxic therapy by Marina V. Vitsenya, Irina V. Barinova, Nana V. Pogosova, Tatevik A. Terteryan, David T. Kuchiev, Yulia V. Khrushcheva, Anna A. Gerasimova, Anastasiya Y. Filatova, Nursiyat M. Ibragimova, Olga O. Frolkova, Fail T. Ageev

“…The cardiorespiratory endurance was reduced, with median peak oxygen consumption being 71% of the predicted values. Anxiety symptoms were found in 45 (50%) patients, depressive symptoms in 16 (17.8%), high stress levels in 51 (56.7%), and sleep disorders in 80 (88.9%). …”
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Bioinformatics and immunoinformatics assisted multiepitope vaccine construct against Burkholderia anthina by Maha A. Alshiekheid, Ali M. Dou, Mohammad Algahtani, Wafa Abdullah I. Al-Megrin, Yaseer Ali Alhawday, Arwa Essa Alradhi, Khulud Bukhari, Basmah F. Alharbi, Ahmed N. Algefary, Basmah Awwadh Alhunayhani, Khaled S. Allemailem

“…VaxiJen v2.0 web server predicted that the vaccine construct is probable antigenic in nature with 0.6320 predicted value. Furthermore AllerTOP v. 2.0 tool predicted that the designed vaccine construct is non allergic in nature. …”
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Associations of Blood Pressure and Heart Rate and Their Contribution to the Development of Cardiovascular Complications and All-Cause Mortality in the Russian Population of 25-64 Y... by S. A. Shalnova, V. A. Kutsenko, A. V. Kapustina, E. B. Yarovaya, Yu. A. Balanova, S. E. Evstifeeva, A. E. Imaeva, S. A. Maksimov, G. A. Muromtseva, N. V. Kulakova, O. N. Kalachikova, T. M. Chernykh, O. A. Belova, G. V. Artamonova, E. V. Indukaeva, Yu. I. Grinshtein, R. A. Libis, D. V. Duplyakov, O. P. Rotar, I. A. Trubacheva, V. N. Serebryakova, A. Yu. Efanov, A. O. Konradi, S. A. Boytsov, O. M. Drapkina

“…To study the relationship of blood pressure (BP) and heart rate (HR) in a sample of men and women 25-64 years old and their predictive value for the development of fatal and non-fatal cardiovascular diseases (CVD) and mortality from all causes.Material and methods. …”
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Predictive multigenic scale. Analysis of own results in metastatic breast cancer by R. M. Paltuev, S. N. Aleksakhina, A. S. Artemyeva, E. A. Baychorov, S. Yu. Bakharev, A. A. Bozhok, V. A. Vasin, V. I. Vladimirov, O. A. Volynshchikova, A. Yu. Vorontsov, E. A. Gaysina, A. A. Hoffman, E. N. Imyanitov, V. V. Klimenko, A. V. Komyakhov, M. M. Konstantinovа, M. V. Kopp, A. G. Kudaybergenova, I. A. Lalak, D. L. Matevosyan, N. M. Mudzhiri, O. V. Poltareva, O. I. Sevryukova, V. F. Semiglazov, T. Yu. Semiglazova, M. M. Urezkova, L. A. Churilova

“…We analyzed the expression of 28 genes with a high predictive value that have been substantially studied (including ESR1, PGR, PIK3CA, BCAR4, BCAS2, CCND1, CCND2, CCND3, FOXA1, Erb2, EGFR, CDH3, FOXC1, KRT14, KRT5, CD274, CDK4, CDK6, P53, PTEN, BRCA1, BRCA2, CHEK2, CLDN3, CLDN7, AR, TOP2a, TUBBIII). …”
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Development of a predictive model for metachronous liver metastasis in gastric cancer by Siyuan Wang, Siyuan Wang, Gaozan Zheng, Fengsu Wu, Ye Tian, Xinyu Qiao, Xinyu Dou, Hanjun Dan, Hanjun Dan, Guangming Ren, Liaoran Niu, Pengfei Wang, Lili Duan, Yumao Yang, Jianyong Zheng, Fan Feng

“…Besides conventional parameters, we identified and incorporated peripheral blood monocyte and lymphocyte counts as novel predictors, demonstrating their independent predictive value. Integrating these factors into nomogram could enhance predictive accuracy of MLM.…”
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Prognostic Value and Correlation Between WT1 Overexpression and NPM1 Mutation in Patients with Acute Myeloblastic Leukemia by LL Girshova, IG Budaeva, EG Ovsyannikova, SO Kuzin, DV Motorin, RSh Badaev, DB Zammoeva, VV Ivanov, KV Bogdanov, OS Pisotskaya, YuV Mirolyubova, TS Nikulina, YuA Alekseeva, AYu Zaritskii

“…The research showed the predictive value of a lower limit level of WT1 on day 28 of treatment (100 per 104 copies ABL), and for the first time, the importance of the early assessment WT1 expression reduction on day 14 of induction therapy.…”
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Endothelial activation and stress index is a reliable predictor for the prevalence and mortality outcomes of stroke by Yongwei Huang, Zongping Li, Jianjun Wang, Decai Wang, Xiaoshuang Yin

“…The area under the curve (AUC) was measured to estimate the EASIX predictive values for stroke prevalence and mortality outcomes. …”
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The role of triglyceride-glucose index in the progression of cardiovascular-kidney-metabolic syndrome: findings from the China health and retirement longitudinal study by Xingyu Zhou, Xingyu Zhou, Yisi Liu, Yisi Liu, Yisi Liu, Yisi Liu, Jiafei Peng, Jiafei Peng, Jiafei Peng, Jiafei Peng, Xianliang Zhou, Hongtao Wei, Hongtao Wei, Hongtao Wei, Hongtao Wei

“…Q1: HR 2.21, 95% CI 1.58–3.08, P < 0.01) in stage 1.ConclusionElevated TyG index is a significant predictor of CKM progression, particularly via the development of metabolic abnormalities. Its predictive value varies across age groups and CKM stages. …”
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Prognostic significance of NT-proBNP and sST2 in patients with heart failure with preserved and mildly reduced ejection fraction by V. I. Podzolkov, N. A. Dragomiretskaya, A. V. Tolmacheva, I. I. Shvedov, A. A. Ivannikov, I. V. Akyol

“…At ROC analysis to one-year adverse events, both NT-proBNP and sST2 showed a significant predictive value in patients with EF >40% with an optimal cut-off value of 746 pg/ml (AUC 0.709; p = 0.005, sensitivity 62%, specificity 69%) and 27.1 ng/ml (AUC 0.742; p = 0.03, sensitivity 80%, specificity 75.8%) respectively.Conclusion: NT-proBNP levels >746 pg/ml and sST2 >27.1 ng/ml should be considered as predictors of poor prognosis in CHF patients with LVEF >40%.…”
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Effectiveness and safety of acupuncture and related therapies for pediatric asthma: a systematic review and meta-analysis by Jixuan Wang, Jixuan Wang, Shun Fan, Shun Fan, Kaihan Su, Kaihan Su, Jiacheng Zhang, Jiacheng Zhang, Xuanjun Lu, Xuanjun Lu, Shengxuan Guo, Shengxuan Guo, Siyuan Hu, Siyuan Hu

“…Compared to ST, the addition of acupuncture has significantly improved the percent predicted values of forced expiratory volume in 1 second (FEV1pred%) [MD = 6.02, 95% CI (1.28, 10.76), p = 0.0128], No significant effect on forced expiratory volume in 1 second/forced vital capacity (FEV1/FVC) has been observed [MD = 3.36, 95% CI (−0.76, 7.48), p = 0.1097]. …”
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Expression of Astragalus membranaceus phenylalanine ammonia-lyase gene in Pichia pastoris by Zhang Jianhui, Wang Shoufeng

“…SDS-PAGE demonstrated that a sharp 78 ku protein which was equal to the predicted value was expressed in the supernatant in contrast to the parent pPIC9K. …”
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MULTISPIRAL COMPUTED TOMOGRAPHY VERSUS MYOCARDIAL BIOPSY IN DIAGNOSTICS OF YOCARDITIS AND PROGNOSIS EVALUATION OF DILATION CARDIOMYOPATHY SYNDROME by I. N. Alieva, O. V. Blagova, N. V. Gagarina, A. V. Nedostup, E. A. Kogan, V. P. Sedov, V. V. Kadochnikova, A. E. Donnikov, V. A. Zaydenov, A. G. Kupriyanova, S. K. Ternovoy

“…Sensitivity and specificity of all types of delayed accumulation in diagnostics of myocarditis were 63,3% and 78,7%, positive and negative predictive value 86,1% and 50,7%, subepicardial and transmural types — 49,0%, 83,0%, 85,7%, 43,8%, respectively. …”
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Stress hyperglycemia ratio as a biomarker for early mortality risk stratification in cardiovascular disease: a propensity-matched analysis by Mingxing Lei, Yan Li, Longcan Cheng, Nan Tang, Jie Song, Mi Song, QingQing Su, Mingxuan Liu, Shihui Fu, Feng Lin, Yuan Gao

“…The incremental predictive value of SHR support its utility for risk stratification, particularly for short-term outcomes, but its prognostic value fades for long-term mortalities. …”
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