Predictive Models Using Machine Learning to Identify Fetal Growth Restriction in Patients With Preeclampsia: Development and Evaluation Study by Qing Hua, Fengchun Yang, Yadan Zhou, Fenglian Shi, Xiaoyan You, Jing Guo, Li Li

“…ML models were constructed to evaluate the predictive value of maternal parameter changes on preeclampsia combined with FGR. …”
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Using the ORACLE Risk Score to Assess Hemorrhagic Risk in Patients with Acute Coronary Syndrome and Atrial Fibrillation by V. A. Brazhnik, L. O. Minushkina, A. D. Erlikh, E. D. Kosmacheva, M. A. Chichkova, N. R. Khasanov, D. A. Zateyshchikov

“…The ORACLE risk score had the greatest prognostic value (area under the ROC curve 0.874±0.0416, sensitivity 82.7%, specificity 79.1%). The predictive value of the HAS-BLED risk score was slightly lower (area under the ROC curve 0.710±0.0360, sensitivity 63.2%, specificity 56.8%). …”
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Analysis of factors affecting the accuracy of 18F-fluorodeoxyglucose positron emission tomography combined with computed tomography in case of suspected prosthetic valve infective... by I. P. Aslanidi, E. Z. Golukhova, D. M. Pursanova, O. V. Mukhortova, I. V. Shurupova, I. V. Ekaeva, T. A. Katunina, T. A. Trifonova

“…Thus, the sensitivity, specificity and diagnostic accuracy of PET/CT in the diagnosis of PVE were 92%, 67% and 84%, respectively; positive and negative predictive values — 85% and 80%. The analysis of the odds ratio did not reveal the relationship of low inflammatory activity, the interval between surgery and PET/CT from 3 to 6 months, and long-term ABT before PET/CT with false PET/CT results (p>0,05). …”
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Improving chest pain risk assessment: validation of HEART, TIMI, GRACE, EDACS-ADP, and HET for MACE prediction in the emergency department by Mehdi Nasr Isfahani, Hamidreza Mohseni, Elahe Nasri Nasrabadi, Nizal Sarrafzadegan

“…Diagnostic performance of the risk scores was evaluated using receiver operating characteristic (ROC) curve analysis, including calculation of sensitivity, specificity, positive and negative predictive values, and likelihood ratios at clinically relevant cut-off thresholds. …”
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External validation of SYNTAX score II in a real-world cohort undergoing coronary artery bypass grafting by Philipp Angleitner, Hannes Abfalterer, Alexandra Kaider, Emely Manville, Martin Bichler, Michael Graber, Leo Pölzl, Daniel Zimpfer, Sigrid Sandner, Nikolaos Bonaros

“…SYNTAX Score II, EuroSCORE II, the logistic EuroSCORE, and ACEF Score offer comparable predictive value towards 4-year mortality.…”
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Association between different dimensions of the C-reactive protein-triglyceride-glucose index and future cardiovascular disease risk in individuals with cardiovascular-kidney-metab... by Jintao Chen, Liying Yan, Lei He, Weixue Wang

“…Longitudinal monitoring of CTI changes over time can help early identification of high CVD risk in this population, and its predictive value is significantly superior to that of the TyG index. …”
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Building a risk prediction model for anastomotic leakage postoperative low rectal cancer based on Lasso-Logistic regression by Zhenhao Quan, Lin Lin, Renwei Huang, Kaiyu Sun, Feipeng Xu

“…H-L goodness of fit test showed that there was no significant difference between the predicted value of the model and the actual observed value (χ 2  = 6.438, P = 0.598). …”
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Detection of urinary levels of matrix metalloproteinase-7 and tumor necrosis factor-like weak inducer of apoptosis in patients with IgA nephropathy and values in predicting disease... by Ma Yong-duo, Wang Cong, Li Hai-xiang, Wu Huan

“…ObjectiveTo explore the expressions of urinary matrix metalloproteinase-7 （MMP-7） and tumor necrosis factor-like weak inducer of apoptosis （TWEAK） in patients with IgA nephropathy （IgAN） and examine its predictive value.MethodsFrom January 2018 to March 2021，115 IgAN patients and 50 normal subjects （control group） were selected.Based upon the progress of IgAN，115 cases of IgAN patients were divided into two groups of IgAN progressive （<italic>n</italic>=42） and IgAN non-progressive （<italic>n</italic>=73）.According to the IgAN Oxford classification criteria，they were assigned into two groups of MEST-C≥3 （<italic>n</italic>=45） and MEST-C&lt;3 （<italic>n</italic>=70）.The levels of urinary MMP-7 and TWEAK were compared between two groups.Multivariate Logistic regression was utilized for analyzing the risk factors of IgAN progression.Receiver operating characteristic （ROC） curve was plotted for examining the values of urinary MMP-7 and TWEAK levels in predicting IgAN progression.ResultsThe levels of urinary MMP-7 （15.72±7.85 <italic>vs</italic> 6.92±0.53 ng/mL） and TWEAK were significantly higher in IgAN progressive group than those in IgAN non-progressive group ［（958.47±42.60） <italic>vs</italic> （206.73±15.18）ng/mL，<italic>P</italic>&lt;0.001］.The levels of urinary MMP-7 ［（23.92±9.27） <italic>vs</italic> （18.15±8.36） ng/mL］ and TWEAK ［（1408.70±71.15） <italic>vs</italic> （1036.28±50.72） ng/mL］ were significantly higher in MEST-C≥3 score group than those in MEST-C&lt;3 score group （<italic>P</italic>&lt;0.001）.Multivariate Logistic regression analysis indicated that elevated levels of MMP-7 ［<italic>OR</italic>=2.986 95%<italic>CI</italic>（2.146，-8.513）］ and TWEAK ［<italic>OR</italic>=3.370 95%<italic>CI</italic>（2.752，-10.118）］ were the risk factors affecting the progression of IgAN.Receiver operating characteristic （ROC） curve indicated that the area under the curve （AUC） of MMP-7 and TWEAK in predicting IgAN progression was 0.948 （95% <italic>CI </italic>0.885-0.997） with a sensitivity of 97.5% and a specificity of 85.0%.Correlation analysis indicated that the urinary levels of MMP-7 and TWEAK were significantly positively correlated with M，E，S and T （<italic>P</italic>&lt;0.001）.ConclusionThe elevated urinary levels of MMP-7 and TWEAK are the risk factors affecting the progression of IgAN.Both may be used as biological indicators for predicting the progression of IgAN.…”
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Cerebrospinal Fluid Leakage Combined with Blood Biomarkers Predicts Poor Wound Healing After Posterior Lumbar Spinal Fusion: A Machine Learning Analysis by Pang Z, Ou Y, Liang J, Huang S, Chen J, Huang S, Wei Q, Liu Y, Qin H, Chen Y

“…Calibration curve analysis showed good consistency between nomogram-predicted values and actual measurements.Conclusion: SLSI, albumin, postoperative glucose, CSFL, NEU and CRP were identified as significant risk factors for PWH after posterior lumbar spinal fusion. …”
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Serum FGF23 and DPP4 Levels as Biomarkers for Coronary Artery Disease Severity in Type 2 Diabetic Patients with Coronary Heart Disease by Zhong X, Liang Z, Liao H, Zhan Y, Li G, Wu H, Li J

“…Receiver operating characteristic (ROC) curve analysis was used to evaluate the predictive value of these biomarkers.Results: Serum levels of FGF23 and DPP4 were significantly higher in the T2DM+CHD group than in the T2DM-only group (P< 0.05), and increased progressively with the severity of CAD (P< 0.05). …”
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PREDICTIVE RELEVANCE OF DIFFERENT CLINICAL AND LABORATORY FINDINGS FOR HIGHER MORTALITY IN PATIENTS WITH COVID-19 IN A SINGLE CENTER COHORT: NEUTROPHIL/ LYMPHOCYTE RATIO, HIGH CR... by Oğuz Evlice, Fatih Kuş, Özlem Arık, Murat Bektaş

“…Therefore, we aimed to evaluate the predictive value of different clinical and laboratory parameters in disease severity and mortality in patients with COVID-19. …”
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Evaluative performance of TyG-ABSI versus traditional indices in relation to cardiovascular disease and mortality: evidence from the U.S. NHANES by Xin Zheng, Wenjing Zhang, Feng Yang, Leigang Wang, Bing Yu, Bin Liang

“…This study aims to explore the association between TyG-ABSI and cardiovascular events in individuals with MetS and compare its predictive value with the traditional TyG index in this specific population. …”
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Aneuploidy screening in women of advanced age in the public healthcare setting of a low- to middle- income country – an observational cohort study by L Geerts, N Du Toit, M Schoeman

“…In the SA public sector, DS screening and confirmatory genetic testing are fully state subsidised for women of advanced maternal age (AMA) but, owing to the low positive predictive value of AMA-based screening, ultrasound-based screening is also offered. …”
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Anti-carbamylated protein antibodies in ACCP-negative and ACCP-positive patients with rheumatoid arthritis by D. A. Dibrov, A. S. Avdeeva, M. E. Diatroptov, E. L. Nasonov

“…A weak direct correlation between anti-CarP and DAS28 was found in the ACCP(–) RA group.Conclusion. We studied the predictive value of anti-CarP as an adjuvant biomarker in ACCP(+) and ACCP(–) subtypes of RA. …”
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Association between albumin and short-term outcomes of unplanned early readmission emergency department patients: A retrospective cohort study. by Liang Zhou, Xiaona Cai, Kunpeng Hu, Shuo Tang, Dandan Gao, Xiaojuan Zhang, Yin Wu, Li He, Bangfu Zhou, Ruoyu Wu, Zhigang Zhang

“…The purpose of this study was to analyze the predictive value of albumin for the short-term survival of patients with unplanned early readmission to the emergency department (ED).…”
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A framework for parsing psychopathological heterogeneity: initial application in a large-scale unselected community sample by Chaoyi Wu, Chenyu Yuan, Yinqing Fan, Ang Hong, Zhiling Wu, Zhen Wang

“…Results showed that these profiles provided unique predictive value for RDoC negative valence constructs beyond both dichotomous diagnostic status and purely dimensional approach. …”
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Dynamic serum lactate dehydrogenase monitoring during the acute phase and association with in-hospital all-cause mortality risk in large vessel occlusion acute ischemic stroke pati... by Weiwei Gao, Lijuan Cai, Xingyu Chen, Renjing Zhu

“…However, the dynamic changes and predictive value of serum LDH during the acute phase in patients with large vessel occlusion acute ischemic stroke (LVO-AIS) remain insufficiently characterized. …”
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Japanese experience of newborn screening for lysosomal storage diseases and adrenoleukodystrophy by Takanori Onuki, Makiko Tajika, Yohei Sugiyama, Masaru Shimura, Keiko Ichimoto, Toju Tanaka, Hiromi Nyuzuki, Motomichi Kosuga, Ohsuke Migita, Tetsuya Ito, Hideo Sasai, Ryosuke Bo, Junpei Hamada, Takashi Hamazaki, Norio Sakai, Takahito Inoue, Kimitoshi Nakamura, Torayuki Okuyama, Kei Murayama

“…In contrast, the positive predictive value was low and false-positive rates was elevated, particularly for PD, MPS II, and ALD, have been attributed to pseudodeficiency alleles and methodological differences. …”
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Skin rash in metastatic hormone sensitive prostate cancer patients treated with apalutamide: a retrospective multicenter study in Korea by Won Tae Kim, Hyun Ho Han, Seok Joong Yun, Seong Hyeon Yu, Taek Won Kang, Yun-Sok Ha, Jun Nyung Lee, Tae Gyun Kwon, Byung Hoon Kim, Won Ik Seo, Chan Ho Lee, Jae Il Chung, Jung Ki Jo, U-Syn Ha, Ji Youl Lee, Hwang Gyun Jeon, Seong Il Seo, Kyo Chul Koo, Byung Ha Chung, Jong Wook Kim, Joongwon Choi, Jong Wook Park, Hongzoo Park, Sungchan Park, Soo Dong Kim, Hak Min Lee, Sung Kyu Hong, Jae Young Joung

“…This study aims to investigate the incidence rate of skin rash and the predictive value of inflammation markers for skin rash in real-world Korean patients. …”
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Redefining the role of IL-18 in post-surgical recovery and sepsis: a key mediator of inflammation resolution by Ioanna Papatheodorou, Gabriela Blažková, Veronika Bosáková, Zuzana Tomášiková, Erin Spearing, Robin Klieber, Pavel Ostašov, Julie Štíchová, Martina Dvončová, Alexandra Mýtniková, Jan Emmer, Kamila Bendíčková, Tomáš Tomáš, Vladimír Šrámek, Petros Kolovos, Monika Holubová, Martin Helán, Marcela Vlková, Jan Frič, Marcela Hortová-Kohoutková

“…Finally, TNF-α/IL-18 ratio showed a high predictive value of clinical severity in septic patients. …”
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