Early Postoperative Increase in Transforming Growth Factor Beta-1 Predicts Microvascular Flap Loss in Reconstructive Surgery: A Prospective Cohort Study by Rihards Peteris Rocans, Janis Zarins, Evita Bine, Insana Mahauri, Renars Deksnis, Margarita Citovica, Simona Donina, Sabine Gravelsina, Anda Vilmane, Santa Rasa-Dzelzkaleja, Olegs Sabelnikovs, Biruta Mamaja

“…We aimed to investigate the predictive value of postoperative changes in transforming growth factor beta-1 (TGF-β1) for microvascular flap complications. …”
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Developing an electronic surprise question to predict end-of-life prognosis in a prospective cohort study of acute hospital admissions by Baldev Singh, Nisha Kumari-Dewat, Adam Ryder, Vijay Klaire, Hannah Jennens, Kamran Ahmed, Mona Sidhu, Ananth Viswanath, Emma Parry

“…For the GSFSQ-No classification, the mortality odds ratio was 12.4 (11.4–13.5) (p<0.001) vs GSFSQ-Yes (c-statistic 0.72 (0.70–0.73), p<0.001; accuracy, positive and negative predictive values 81.2%, 83.6%, 83.6%, respectively). Had the tool been utilised at the time of admission, the potential to reduce possibly avoidable subsequent hospital admissions, death-in-hospital and bed days was significant (p<0.001). …”
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Assessment of Long-Read Sequencing-Based Congenital Adrenal Hyperplasia Genotyping Assay for Newborns in Fujian, China by Xudong Wang, Xingxiu Lu, Faming Zheng, Kun Lin, Minjuan Liao, Yi Dong, Tiantian Chen, Ying He, Mei Lu, Jing Chen, Yanfang Li, Yulin Zhou

“…Finally, 66 neonates were diagnosed with CAH, with a positive predictive value of 28.82%. Based on this data, the overall prevalence of CAH in Fujian was estimated to be 1:26,883. …”
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Risk factors of bone metastasis in lung adenocarcinoma by Zhongnian Cao, Rong Zheng, Jing Li, Xuejuan Wang, Chao Ding, Fan Zhang, Jianhua Geng, Zhengmao Wei, Rong Fan

“…A receiver operating characteristic curve was used to verify the predictive value of the regression model, and the area under the curve was 0.912 (P < 0.001). …”
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Foreword

“…“Comparative Analysis of Historic Grade 1 Korean Textbooks at the Moscow Institute of Oriental Studies” contrasts materials from pre- and post-liberation periods, highlighting differences in pedagogy, orthography, and linguistic content, and underscoring their historical and educational value. Editors and Editorial Board invite the regular and new readers to engage with the content, to question, challenge, and reflect. …”
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Quality and content evaluation of thyroid eye disease treatment information on TikTok and Bilibili by Haisheng Wang, Huahong Zhang, Jiamin Cao, Feng Zhang, Wei Xiong

“…Quality, reliability, and educational value were assessed using the Global Quality Score (GQS), modified DISCERN (mDISCERN), Patient Education Materials Assessment Tool (PEMAT), and Journal of the American Medical Association (JAMA) benchmark criteria. …”
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Validating social media data reliability for cultural ecosystem services mapping in data-scarce GIAHS: A mixed-methods approach in hani rice Terraces by Luying Yang, Yanbo Li, Xiaoyan Wei

“…The results show that: (1) Among the places identified as possessing CESs via questionnaire method, 90 % of places with aesthetic value (AV), 90 % of places with cultural heritage value (CHV), 91 % places with cultural diversity value (CDV), and 80 % of places with scientific &amp; educational value (SEV) were also identified using social media data. …”
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Lessons from the Frontline: A Phenomenological Study into Faculty Members’ Experiences with Challenges of Remote Online Exams in Medical Sciences Universities by Mostafa Hadavinejad, Mahdieh Azin, Asieh Fatemidokht, Jalal Hassanshahi, Afsaneh Amiri Khorasani, Foad Iranmanesh

“…While online assessments can improve logistical efficiency and reduce certain stressors, ongoing concerns about academic integrity, technical preparedness, and educational value persist. Addressing these issues requires investment in reliable infrastructure, comprehensive faculty training, and innovative valid assessment methods.…”
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Association of Inflammatory and Metabolic Markers with Mortality in Patients with Postoperative Femur Fractures in the Intensive Care Unit by Metin Kilinc, Enes Çelik, Ibrahim Demir, Semih Aydemir, Hakan Akelma

“…Linear regression, logistic regression, and Receiver Operating Characteristic (ROC) analyses were performed to determine the predictive value of these markers for ICU mortality. <i>Results</i>: The mean age of the patients was 76.3 ± 9.6 years, and 52.1% were female. …”
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Construction of a predictive model for cerebral small vessel disease MRI burden based on β2-microglobulin and lipoprotein(a) by Xiaoyan LI, Hongge JI, Tingting WANG, Yingying LI, Xijing ZHA, Bin LI, Dan JIANG

“…Objective To construct a predictive model for cerebral small vessel disease (CSVD) MRI burden based on β2-microglobulin (β2-MG) and lipoprotein(a) [Lp(a)], analyze its predictive value, and validate the model. MethodsA total of 138 CSVD patients admitted to Anhui No.2 Provincial People’s Hospital from February 2023 to August 2024 were enrolled. …”
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Validation of an Automated High-Throughput Multiplex Real-Time PCR Assay for Detection of Enteric Protozoa by Rachel Lau, Jason Kwan, Kimberley Marks-Beaubrun, Ruben Cudiamat, Min Qun Ellen Chen, Krista Orejana, Filip Ralevski, Andrea K. Boggild

“…<b>Results</b>: Among 461 unpreserved fecal specimens, sensitivity, specificity, positive predictive and negative predictive values of the enteric multiplex for fresh specimens were as follows: 93%, 98.3%, 85.1%, 99.3% for Bh; 100% for all measures in <i>Cryptosporidium</i> and Cc; 100%, 99.3%, 88.5%, 100% for Df; 33.3%, 100%, 100%, 99.6% for Eh; and 100%, 98.9%, 68.8%, 100% for Gl, respectively. …”
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Development of an electrocardiographic prediction model for outflow tract idiopathic premature ventricular contraction with decreased left ventricular ejection fraction by Pinliang Liao, Xiaolian Cai, Wen Zhang, Min Ou, Heling Ren, Maoqin Shu

“…Decision curve analysis (DCA) assessed clinical applicability, and net reclassification improvement (NRI) along with integrated discrimination improvement (IDI) indices were calculated to assess additional predictive value compared with traditional PVC burden. …”
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Improving prediction accuracy of hospital arrival vital signs using a multi-output machine learning model: a retrospective study of JSAS-registry data by Yasuyuki Kawai, Koji Yamamoto, Keisuke Tsuruta, Keita Miyazaki, Hideki Asai, Hidetada Fukushima

“…Model performance was assessed by comparing the predicted values with the actual hospital arrival measurements using mean absolute error, R² score, residual standard deviation, and Spearman’s correlation coefficient. …”
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A predictive model for WHO/ISUP pathologic grading of renal clear cell carcinoma based on CT radiomics: a multicenter study by Chunying Wu, Yuzhen Xi, Juanjuan Hu, Guodong Li, Xu Wang, Xiaofei Jiao, Zhongxiang Ding, Weiying Sun

“…Abstract Objective This study aims to evaluate the predictive value of CT radiomics combined with clinical-imaging features for the WHO/ISUP pathological grade of clear cell renal cell carcinoma(ccRCC). …”
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Effect of GLP-1 Receptor Agonists (Liraglutide) on Glycemic Parameters and Circulating miRNA Expression in Type 2 Diabetes Mellitus by Aqeel Meer AL-ZAMILY

“…ROC analysis showed strong diagnostic performance for miRNA-146a (AUC = 0.869) and miRNA-222 (AUC = 0.816), with moderate predictive value for miRNA-21 (AUC = 0.709). Conclusion: Liraglutide displayed significant glycemic control in patients with T2DM. …”
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Distribution of variants of the <i>TNFA</i> gene regulatory sites among Russian women of Caucasian origin with leiomyoma by V. I. Konenkov, A. V. Shevchenko, V. F. Prokofiev, E. G. Koroleva

“…The diagnostic specificity of this index was 100%, and the predictive value of this quotient reached 13.3, thus implying a 99.9% probability of a correct prediction. …”
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A nomogram for predicting malnutrition risk in patients with chronic heart failure and correlation study between GHRL, MSTN, CRP, Hs-CRP by Yuling Zha, Chengshuai Liu, Yuping Zhou, Miao Kong, Jinlei Liu, Lu Jing, Hailati Gulimila

“…The nomogram developed in this study demonstrated robust predictive value for identifying malnutrition in this population. …”
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Association between international normalized ratio-to-albumin ratio and mortality in critically ill patients with gastrointestinal bleeding: a retrospective MIMIC-IV database study by Xingyi Yang, Shasha Ying, Lihong Lv, Yishu Ji, Jiaqian Ying, Huyan Ke

“…Abstract Background While the international normalized ratio-to-albumin ratio (PTAR) is an established independent prognostic indicator for various diseases, its predictive value for clinical outcomes in critically ill patients with acute gastrointestinal bleeding (GIB) has not been systematically evaluated. …”
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Association of Heart Rate Variability with the Psychosocial Stress Level in Men 41-44 Years Old Living in Moscow by O. M. Drapkina, V. B. Rozanov, A. V. Kontsevaya, O. Yu. Isaykina, G. A. Muromtseva, M. B. Kotova, E. S. Akarachkova

“…The results of correlation and multiple regression analysis confirmed that these HRV indicators are statistically significantly associated not only with PS, but also with other indicators (age, waist / hip ratio, diastolic blood pressure). However, their predictive value turned out to be low, and the proportion of the explained variance of HRV indices ranged from 2.5 to 13.1%.Conclusion. …”
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Time-Course Renal and Pulmonary Injury Analysis and Bioinformatics Screening of Core Pathogenic Genes and Immune Cell Infiltration Patterns in a Sepsis by Apizi A, Li J, Kamilijiang P, Yang CB, Wang ZK, Chai RF, Yu ZX

“…The five identified sepsis-related genes have predictive value in assessing sepsis risk. Insights into the interactions between key genes and immune cell populations may contribute to improved clinical management of sepsis.Keywords: GEO, immune cell infiltration, key genes, nomogram, sepsis…”
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