Harnessing 3D printing in bone tissue engineering by Suchitra Nishal, Parmita Phaugat, Reena Devi, Vandana Garg, Virender Kumar, Hitesh Chopra, Navidha Aggarwal

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HRM Perspective on Environmentally Sustainable and Climate-Resilient Economies and Communities in Africa: A Systematic Literature Review by Samuel Bangura, Melanie Lourens

“…GHRM is pivotal for sustainable development in Africa, but addressing financial, cultural, and regulatory challenges through targeted strategies is essential to maximize its impact.…”
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Upcycling food waste for microalgae cultivation toward lipid production in a closed-loop and system-integrated circular bioeconomy by Guowei Wu, Jun Wei Roy Chong, Kuan Shiong Khoo, Doris Ying Ying Tang, Pau Loke Show

“…Despite encouraging laboratory-scale outcomes, large-scale implementation remains constrained by feedstock heterogeneity, high energy demands during harvesting and lipid extraction, and regulatory challenges. To overcome these barriers and facilitate scale-up, this review highlights integrative strategies such as metabolic engineering, automated cultivation systems, and a closed-loop microalgae-based biorefinery. …”
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Systematic Review on Algorithmic Trading by David Jukl, Jan Lansky

“…They have become a critical part of modern financial markets because of their efficiency and ability to carry out complex strategies.Objective: This research involves a systematic review that assesses the market impact, technological advancements, strategic approaches and regulatory challenges related to algorithmic trading.Methods: Following PRISMA 2020 guidelines, this study conducts a systematic literature review by screening 1,567 articles across five academic databases, namely IEEE Xplore, ACM Digital Library, SpringerLink, Web of Science and SSRN. …”
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RISK MANAGEMENT COMMITTEE ATTRIBUTES AND PROFITABILITY OF LISTED DEPOSIT MONEY BANKS IN NIGERIA MODERATED BY OPERATIONAL RISK by Ibrahim Aminu, Professor Samuel Eniola Agbi, Dr. Adzor Ibiamke

“…The study recommends that banks prioritize effective operational risk management frameworks to safeguard profitability in the face of growing financial and regulatory challenges. …”
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Mycobacteriophages in the Treatment of Mycobacterial Infections: From Compassionate Use to Targeted Therapy by Magdalena Druszczynska, Beata Sadowska, Agnieszka Zablotni, Lesia Zhuravska, Jakub Kulesza, Marek Fol

“…Although significant obstacles remain—including immune interactions, limited host range, and regulatory challenges—rapid progress in synthetic biology and delivery platforms continues to expand their clinical potential. …”
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Facilitators and barriers to online medical consultation in Iran: a qualitative study exploring the perspectives of healthcare policymakers and administrators using the CFIR framew... by Azadeh Ghasempour, Marzieh Nojomi, Salime Goharinezhad, Neda SoleimanvandiAzar, Zahra Rampisheh

“…However, its integration into the national health system remains limited due to complex systemic, infrastructural, and regulatory challenges. Objective This study uses the Consolidated Framework for Implementation Research (CFIR) to identify and analyze the key facilitators and barriers to OMC adoption in Iran from the perspectives of healthcare policymakers and administrators. …”
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Proposal for Safety Classification of SSC for Land-Based Facilities to Support Nuclear-Powered Submarines by Douglas Brandão Baroni, Hélio Massaharu Murata, Fagner Chagas Rother, Anelise Ruzzarin, William Henrique Silva Profeta, Sad Sandrini Borsoi, Eduardo Ascenso Reis Ribeiro, Luana Soares Jorge

“… The design of land facilities to support nuclear-powered submarines involves complex regulatory challenges due to the unique combination of nuclear, military, and naval aspects. …”
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Integrating Radiogenomics and Machine Learning in Musculoskeletal Oncology Care by Rahul Kumar, Kyle Sporn, Akshay Khanna, Phani Paladugu, Chirag Gowda, Alex Ngo, Ram Jagadeesan, Nasif Zaman, Alireza Tavakkoli

“…The review concludes by discussing translational barriers, including data harmonization, regulatory challenges, and the need for multi-institutional datasets to validate AI-based diagnostic frameworks. …”
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Balancing public safety and civil rights: Successes and challenges of AI-based video surveillance systems by S.S. Vaddiparti, F. Babaiev

“…., the ban on facial recognition in France), whereas China and the United States focus more on security – often at the expense of civil liberties. Regulatory challenges include the misalignment of national laws with international norms, especially regarding data retention and algorithmic bias. …”
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Challenges for operational and business management of rice straw extraction: An analysis based on CIMO-logic and system thinking process with experts by Pascual Cortes-Pellicer, Fernando Castelló-Sirvent

“…Findings: The study reveals several significant barriers, including technological constraints, regulatory challenges, and economic disincentives favouring traditional burning. …”
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Dose-dependent osteoimmunomodulatory effects of amorphous calcium phosphate nanoparticles promote 3D-printed scaffold-mediated bone regeneration by Ming Yan, Baixue Xiao, Anthony Yosick, Bei Liu, Hani A. Awad

“…While growth factors and cells can enhance osteoinduction, the inclusion of biologics in biomaterial scaffolds creates regulatory challenges for clinical translation. To address this, here we describe three-dimensional (3D) printed polycaprolactone (PCL) scaffolds for temporally controlled delivery of osteoimmunomodulatory amorphous calcium phosphate-chitosan nanoparticles (ACPC-NP). …”
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Bridging the Regulatory Divide: A Dual-Pathway Framework Using SRA Approvals and AI Evaluation to Ensure Drug Quality in Developing Countries by Sarfaraz K. Niazi

“…<b>Methods:</b> A comprehensive systematic analysis of current regulatory challenges, proposed solutions, and implementation strategies was conducted through an extensive literature review (202 sources, 2019–2025), expert consultation on regulatory science, AI implementation in healthcare, and pharmaceutical policy development. …”
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A Comprehensive and Systematic Literature Review on Flying Cars in Contemporary Research by Carlos Pérez Carrera, Ömer Ekim Genel, Rosario La Regina, Carmine Maria Pappalardo, Domenico Guida

“…The paper discusses a number of key issues, including technological innovations, infrastructure requirements, societal impacts, and regulatory challenges. In addition, the paper highlights the practical implications and recommendations for the successful integration and adoption of flying cars. …”
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WHO Framework Convention on Tobacco Control Articles 9 and 10 implementation for sustainable tobacco control—a scoping review protocol by Sonu Goel, Diksha Walia, Priyobrat Rajkhowa, Chirag Goel

“…Understanding regional variations in efforts to regulate tobacco products is crucial for formulating specific strategies that effectively address cultural, economic, and regulatory challenges. This comparative examination has the potential to guide policymakers, public health professionals, and researchers in optimizing tobacco control initiatives to expedite progress toward effective implementation of Articles 9 and 10 in both the WHO-SEAR region and globally. …”
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Engineering copper and copper-based materials for a post-antibiotic era by Yingxian Wang, Tongqiang Wen, Fuchao Mao, Fuchao Mao, Fuchao Mao, Fuchao Mao, Shaozhe Yang, Qingwei Zhang, Xiuhong Fu, Chongkai Zhai, Chongkai Zhai, Chongkai Zhai, Chongkai Zhai, Hewei Zhang, Hewei Zhang, Hewei Zhang, Hewei Zhang, Hewei Zhang

“…This review aims to inform future efforts in overcoming the current limitations of copper-based antimicrobials and supporting their potential future integration into applications across medicine, public health, environmental protection, and agricultural innovation, contingent upon resolving current translational and regulatory challenges.…”
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Biomimetic nanovaccines in cancer therapy: mechanisms, efficacy, and clinical translation by Dilinaer Wusiman, Yu Wang, Minghao Wang, Jie Wang, Ruicheng Wu, Zhouting Tuo, Zhipeng Wang, Qingxin Yu, Zhaohong An, William C. Cho, Dengxiong Li, Wuran Wei, Dechao Feng

“…The review also addresses the technical and regulatory challenges in developing biomimetic nanovaccines and offers insights into future innovations that could facilitate their clinical translation.…”
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Unveiling practical insights of eHealth implementation in Europe: a grey literature review on legal, ethical, financial, and technological (LEFT) considerations by B. E. Bente, N. Beerlage-de Jong, R. M. Verdaasdonk, J. E. W. C. van Gemert-Pijnen

“…This study uses grey literature to explore practical experiences and strategies in addressing LEFT challenges during eHealth implementation.ObjectiveThis study aims to explore real-world experiences and perspectives on the legal, ethical, financial, and technological (LEFT) challenges encountered during eHealth implementation.MethodsA grey literature review was conducted by querying databases BASE and Policy Commons, consulting expert references for relevant reports, and using snowball sampling to identify additional relevant grey literature.ResultsWhile the aim of this study was to explore practical experiences, the grey literature mainly reflects policy-level concerns, including strategic and regulatory challenges, with limited insight into how organizations navigate eHealth implementation in practice. …”
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Co-encapsulated Ce6 + CpG and biopeptide-modified liposomes for enhanced transdermal photo-immunotherapy of superficial tumors by Shaozhen Wang, Chen Yang, Yuanyuan Zhang, Yi Hu, Lan Xiao, Weiping Ding, Bensheng Qiu, Fenfen Li

“…As a topical therapeutic agent, Ce6/CpG@Lip-TD circumvents the regulatory challenges associated with the systemic delivery of nanomaterials and significantly reduces systemic side effects, holding great promise for rapid translation into clinical applications.…”
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Understanding Home Health Agencies' Perspectives Toward Telehealth Use Among Home Health Stakeholders in the Post–COVID-19 Era: Qualitative Interview Study by Daniel Spertus, Kiran Abraham-Aggarwal, Mark Aaron Unruh, Jiani Yu, Kathryn H Bowles, Michael P Thompson, Cisco Espinosa, Hye-Young Jung, Madeline R Sterling

“…ConclusionsWhile stakeholders recognize the benefits of telehealth in HHC, financial and regulatory challenges pose substantial barriers to its sustainability. …”
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