Characteristics of TSPO expression in marmoset EAE by Irene Falk, Dragan Maric, Emily Leibovitch, Pascal Sati, Jennifer Lefeuvre, Nicholas J. Luciano, Joseph Guy, Seung-Kwon Ha, David R. Owen, Franklin Aigbirhio, Paul M. Matthews, Daniel S. Reich, Steven Jacobson

“…Abstract Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) and is a leading non-traumatic cause of disability in young adults. The 18 kDa Translocator Protein (TSPO) is a mitochondrial protein and positron emission tomography (PET)-imaging target that is highly expressed in MS brain lesions. …”
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Monozygotic twins with myocarditis and a novel likely pathogenic desmoplakin gene variant by Antheia Kissopoulou, Eva Fernlund, Christina Holmgren, Eira Isaksson, Jan‐Erik Karlsson, Henrik Green, Jon Jonasson, Rada Ellegård, Hanna Klang Årstrand, Anneli Svensson, Cecilia Gunnarsson

“…Abstract Myocarditis most often affects otherwise healthy athletes and is one of the leading causes of sudden death in children and young adults. Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetically determined heart muscle disorder with increased risk for paroxysmal ventricular arrhythmias and sudden cardiac death. …”
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Generational trends in education and marriage norms in rural India: evidence from the Pune Maternal Nutrition Study by Akanksha A. Marphatia, Akanksha A. Marphatia, Jonathan C. K. Wells, Alice M. Reid, Marios Poullas, Aboli Bhalerao, Pallavi Yajnik, Chittaranjan S. Yajnik

“…We aimed to investigate changes in social norms across generations in rural Maharashtra, India.MethodsTo understand the status quo, we identified education levels and marriage ages typical of contemporary young adults in rural Maharashtra using the National Family Health Survey. …”
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Determining the intention of receiving the influenza vaccine: a cross-sectional survey among international and domestic college students in the USA by Charles Liu, Jiying Ling, ChengChing Liu, Angela Chia-Chen Chen, Nagwan Zahry, Ravichandran Ammigan, Loveleen Kaur

“…Objective Vaccination is the most effective strategy for preventing infectious diseases, yet it is underused in young adults. College students are important targets for the influenza vaccine given this population’s low vaccination rates; however, limited research has focused on international college students’ vaccination status. …”
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The current state of knowledge on the role of NKG2D ligands in multiple sclerosis and other autoimmune diseases by Aleksandra Pogoda-Wesołowska, Nina Sługocka, Agnieszka Synowiec, Klaudia Brodaczewska, Marcin Mejer-Zahorowski, Maciej Ziękiewicz, Wojciech Szypowski, Piotr Szymański, Adam Stępień

“…It is the most common nontraumatic and disabling disease affecting young adults. The incidence and prevalence of MS have been increasing. …”
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Sex-specific alterations in creatine metabolism in cellular compartments of peripheral blood leukocytes in type 1 diabetes by Nina Alchujyan, Elena Aghajanova, Nina Movsesyan, Arthur Melkonyan, Artashes Guevorkian, Armen Andreasyan, Margarita Hovhannisyan

“…A total of 270 Armenian participants were enrolled in the study and were divided into two age groups: Group I - included children and preadolescents; and Group II - included adolescents and young adults. Within each group, the participants were further categorized based on sex and disease duration: Recent-onset T1D (RO-T1D), and Long-term T1D (LT-T1D). …”
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Assessment of adequacy and determinants of HIV related knowledge among senior school students in public schools in Abakaliki Southeast Nigeria by Maria-Lauretta Chito Orji, Ngozi Appolonia Ifebunandu, Chinwe Ifeoma Joe-Akunne, Mmeremikwu Appolus Chidiebere, Stella Echefu, Justus Ndulue Eze

“…Abstract Misinformation, under-information, and disinformation regarding HIV among adolescents may be associated with a high prevalence of HIV among adolescents and young adults. The source of the HIV-related knowledge determines the accuracy and comprehensiveness of the information received. …”
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Inter-session Reliability of Magnetic Nerve Stimulation and Within-Session comparison to Electrical Nerve Stimulation in Evaluating Neuromuscular Function of Knee Extensor Muscles by Romina Ledergerber, Martin Keller

“…Methods This study compares ENS to MNS (validity) and evaluates inter-session reliability in sixteen healthy young adults (11 females, 5 males). Data on resting single twitches (RS), 3-5 superimposed twitches (ST) during maximal voluntary contractions of knee extensors, and resting doublet twitches (RD) were assessed using both MNS and ENS. …”
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Discrete time measures versus trajectories of drinking frequency across adolescence as predictors of binge drinking in young adulthood: a longitudinal investigation by Marie-Pierre Sylvestre, Robert J Wellman, Marilyn N Ahun, Geetanjali Datta, Didier Jutras-Aswad, Jennifer O Loughlin

“…All discrete time measures were associated with sustained binge drinking, notably frequency at age 12 (a bit to try and drinking monthly: (AORs=2.6 (1.7; 3.9) and 2.8 (1.3; 6.1), respectively), age of drinking onset <13 years (AOR=7.6 (3.0; 24.1)), and any age of onset of drinking monthly or more often (AORs=5.1–8.2).Conclusion Youth at risk of sustained binge drinking as young adults can be identified with indicators of early drinking as early as 7th grade (aged 12–13 years). …”
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Emotion dysregulation and impulsivity as overlapping symptoms in adult Attention-Deficit/Hyperactivity Disorder and Borderline Personality Disorder: severity profiles and associati... by Eszter Kenézlői, Lívia Balogh, Szilvia Somogyi, Evelyn E. Lévay, Zsuzsa Halmai, Zsófia Nemoda, Zsolt S. Unoka, János M. Réthelyi

“…Our aims were to describe their differences in the above conditions, investigate their associations with childhood traumatization, and to explore the potential mediation of emotion dysregulation and impulsivity between childhood traumas and personality functioning. Methods Young adults between 18 and 36 years diagnosed with aADHD (n = 100) and BPD (n = 63) were investigated with structured clinical interviews, while age-matched healthy controls (n = 100) were screened for psychiatric disorders. …”
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Prevalence and health consequences of nonmedical use of tramadol in Africa: A systematic scoping review. by Saidou Sabi Boun, Olumuyiwa Omonaiye, Sanni Yaya, Sanni Yaya

“…These groups include: 1) young adults/active populations with varying degrees of prevalence ranging from 1.9% to 77.04%, 2) professionals, where drivers exhibit a relatively high prevalence of tramadol NMU, ranging from 7.2% to 35.1%, and commercial motorcyclists, with a prevalence of 76%, 3) patients, who have a high rate of tramadol NMUs, with prevalence rates ranging from 77.1% to 92%, 4) academics, with a considerable rate of tramadol misuse among substance-using undergraduates (74.2%) and substance-using high school students (83.3%), and 5) other individuals impacted in various ways. …”
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Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design by Haiying Qin, Nirali N Shah, Terry J Fry, Lila Yang, John A Chukinas, Samiksha Tarun, Marie Pouzolles, Christopher D Chien, Lisa M Niswander, Anthony R Welch, Sarah K Tasian, Naomi A Taylor

“…Based on this rigorous preclinical evaluation, our validated clinical grade lintuzumab-CD28/CD3ζ CD33CART immunotherapy is now under evaluation in a first-in-child/first-in-human phase 1 clinical trial for children and adolescents/young adults with relapsed/refractory AML.Trial registration number clinicaltrials.gov; NCT03971799.…”
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Adolescent Youth Survey on HIV Prevention and Sexual Health Education in Alabama: Protocol for a Web-Based Survey With Fraud Protection Study by Henna Budhwani, Ibrahim Yigit, Josh Bruce, Christyenne Lily Bond, Andrea Johnson

“… BackgroundIn Alabama, the undiagnosed HIV rate is over 20%; youth and young adults, particularly those who identify as sexual and gender minority individuals, are at elevated risk for HIV acquisition and are the only demographic group in the United States with rising rates of new infections. …”
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Impact of Comorbidities on Prognosis and Treatment Outcomes in Elderly Patients with Hodgkin Lymphoma by Dávid Tóthfalusi, Boglárka Dobó, Fanni Borics, László Imre Pinczés, Árpád Illés, Zsófia Miltényi

“…<b>Background/Objectives</b>: Hodgkin lymphoma (HL) primarily affects young adults, but about 20% of cases occur in patients over the age of 60 years. …”
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Misconceptions on COVID-19 Risk Among Ugandan Men: Results From a Rapid Exploratory Survey, April 2020 by Keneth Iceland, Kasozi, MacLeod, Ewan, Ssempijja, Fred, Mahero, Michael W., Matama, Kevin, Musoke, Grace Henry, Bardosh, Kevin, Ssebuufu, Robinson, Wakoko-Studstil, Florence, Echoru, Isaac, Tiyo Ayikobua, Emmanuel, Mujinya, Regan, Nambuya, Grace, Onohuean, Hope, Zirintunda, Gerald, Ekou, Justine, Welburn, Susan Christina

“…Of female respondents, 76.4% considered mortality from COVID-19 to be different between the young and the elderly (RR = 1.7, 95% CI: 1.01–2.92) and 92.7% believed young adults would show fewer signs than the elderly, and 71.4% agreed that elderly COVID-19 patients would show more severe signs than the young (OR = 2.2, 95%CI: 1.4, 4.8). …”
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A prospective randomized controlled trial comparing biphasic cartilage repair implant with microfracture in small chondral lesions of knee: findings at five-year-follow-up by Yao-Yi Kuo, Si-Qi Chiu, Wen-Pei Chang, Chih-Yu Chen, Chih-Hwa Chen, Chen-Kun Liaw, Cheng-Aun Tan, Pei-Wei Weng

“…Abstract Background Full-thickness cartilage defects have a significant impact on the function of joints in young adults, and the treatment of cartilage defects has been a challenge, as cartilage tissue is an avascular tissue. …”
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Strategies to Increase Response Rate and Reduce Nonresponse Bias in Population Health Research: Analysis of a Series of Randomized Controlled Experiments during a Large COVID-19 St... by Christina J Atchison, Nicholas Gilby, Galini Pantelidou, Sam Clemens, Kevin Pickering, Marc Chadeau-Hyam, Deborah Ashby, Wendy S Barclay, Graham S Cooke, Ara Darzi, Steven Riley, Christl A Donnelly, Helen Ward, Paul Elliott

“…ResultsMonetary incentives increased the response rate (completed swabs returned as a proportion of the number of individuals invited) across all age groups, sex at birth, and area deprivation with the biggest increase among the lowest responders, namely teenagers and young adults and those living in more deprived areas. …”
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Prevalence and factors associated with severe fatigue 2 years into the COVID-19 pandemic: a cross-sectional population-based study in Geneva, Switzerland by Silvia Stringhini, Idris Guessous, C Martinez, A Flahault, S Hurst, N Vuilleumier, L Kaiser, K M Posfay-Barbe, O Zimmermann, S Stringhini, A Uppal, P Schaller, J Berthelot, D Pittet, H Baysson, Hélène Baysson, S Yerly, E Lorthe, Mayssam Nehme, Nick Pullen, María-Eugenia Zaballa, A Bal, Clément Romain Hugo Graindorge, Stephanie Schrempft, I Arm-Vernez, A S Azman, D Bachmann, J-F Balavoine, R P Barbe, A R Bouhet, G Bryand-Rumley, F Chappuis, P Collombet, S Coudurier-Boeuf, D S Courvoisier, C de Mestral, P D’ippolito, R Dubos, R Dumont, N El Merjani, N Francioli, C Graindorge, I Guessous, S Harnal, G Kathari, O Kherad, J Lamour, P Lescuyer, A G L’Huillier, A J Loizeau, S Mechoullam, L Metral-Boffod, M Nehme, N Noël, F Pennacchio, J Perez-Saez, G Poulain, C Pugin, N Pullen, V Richard, D Rochat, S Rouzinov, K Samir, H S Ramirez, E Satin, S Schrempft, C Semaani, S Testini, D Urrutia-Rivas, C Verolet, P Vetter, J Villers, G Violot, A Wisniak, M-E Zaballa

“…Heightened fatigue among young adults is partly explained by depressive symptoms. …”
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Types of electronic nicotine delivery systems (ENDS) used by people of different age and smoking status groups: results from a US nationally representative survey by Lucy Popova, Robert T Fairman, David L Ashley, Zachary B Massey, Bai Cham, Ruiyan Luo, Mohammed Alqahtani, Scott Weaver

“…Similarly, 18–29 years old current (vs never) smokers had higher odds of reporting current regular use of refillable tanks (OR=1.80), refillable pods (OR=2.63), closed pods (OR=2.20) and drippers (OR=4.89; p&lt;0.05).Conclusions Both age and smoking status were associated with current regular use of ENDS, especially for youth and young adults. These findings inform regulatory agencies as they monitor and enforce policy on ENDS allowed on the US market.…”
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Concerns Over Vuse e-Cigarette Digital Marketing and Implications for Public Health Regulation: Content Analysis by Eileen Han, Lauren K Lempert, Francesca Vescia, Bonnie Halpern-Felsher

“… Abstract BackgroundElectronic cigarettes (e-cigarettes) are the most used form of tobacco products among adolescents and young adults, and Vuse is one of the most popular brands of e-cigarettes among US adolescents. …”
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