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Unique North American isolates of severe metastatic hypervirulent Klebsiella pneumoniae strain infections with hepatic abscesses seen in young patients within Texas.
Published 2025-01-01“…Country-wide surveillance and whole genome sequencing of these strains is essential to prevent a major public health emergency in the USA.…”
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183
Copper Tolerance of <i>Trichoderma koningii</i> Tk10
Published 2025-01-01“…Whole-genome sequencing revealed six genes associated with copper tolerance, including one superoxide dismutase gene, one peroxidase gene, and three catalase genes linked to copper stress. …”
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184
Characterization of Enterobacter phage vB_EcRAM-01, a new Pseudotevenvirus against Enterobacter cloacae, isolated in an urban river in Panama.
Published 2024-01-01“…Remarkedly, it exhibits a narrow host specificity only infecting E. cloacae. Whole genome sequencing revealed that is a myovirus with a genome size of 178,477 bp, a G-C content of 45.8%, and containing approximately 294 genes. …”
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Pervasive horizontal transmission of Wolbachia in natural populations of closely related and widespread tropical skipper butterflies
Published 2025-01-01“…We demonstrate that low coverage whole genome sequencing data can be used for an exhaustive assessment of Wolbachia infection in natural populations of butterflies, as well as its dynamics in closely related host species. …”
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186
Genomic characterization of noroviruses from an outbreak associated with oysters
Published 2025-02-01“…We next proceeded with whole-genome sequencing and obtained full genomes for 19 samples. …”
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187
Detection and Whole-Genome Characteristics of <i>Bordetella trematum</i> Isolated from Captive Snakes
Published 2025-01-01“…AMR was assessed using the microbroth dilution method, while whole-genome sequencing was performed on the Illumina NextSeq platform. …”
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188
Clostridium tetani bacteraemia in the plague area in France: Two cases
Published 2025-01-01“…Colonies were identified by mass spectrometry and whole genome sequencing, and C. tetani-specific PCR was performed using DNA extracted from dental pulps, calculus and sediments. …”
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Ophiostomatoid fungi associated with pine bark beetles and infested pines in south-eastern Australia, including Graphilbum ipis-grandicollis sp. nov.
Published 2021-09-01“…This study also provides an early example of whole genome sequencing (WGS) approaches replacing traditional PCR-based methods for taxonomic surveys. …”
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191
Genomic Analysis of a Serotype 5 Streptococcus pneumoniae Outbreak in British Columbia, Canada, 2005–2009
Published 2016-01-01“…Comparison of two whole-genome sequenced strains showed only 10 SNVs between them. …”
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192
Severe emm89 Group A Streptococcal Disease Characterized by Toxic Shock and Endocarditis
Published 2019-01-01“…We report a severe, rare case of GAS infection with dissemination including endocarditis and STSS. While whole genome sequencing of blood and pharyngeal isolates did not reveal any unique features attributable to the severe presentation, our approach serves as a template for investigation of severe manifestations of common infections.…”
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Charcot-Marie-Tooth disease: A case report initially manifested by bilateral vocal cord paralysis
Published 2025-01-01“…Diagnosis was confirmed through whole genome sequencing, revealing mutations in genes associated with the disorder.…”
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N-Acetyl cysteine exhibits antimicrobial and anti-virulence activity against Salmonella enterica.
Published 2025-01-01“…In addition, NAC inhibits the expression of virulence genes at sub-inhibitory concentrations in a dose-dependent manner. The whole-genome sequencing revealed that continuous exposure of S. enterica to NAC leads to the development of resistance; these resistant strains are attenuated for virulence. …”
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Pantoea eucrina: Catheter‐Related Bloodstream Infection in a Woman With Short Bowel Syndrome
Published 2025-01-01“…Despite presenting with only minor clinical symptoms, blood cultures from both central and peripheral sites confirmed the presence of P. eucrina, identified by matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOF MS) and whole‐genome sequencing. The infection was successfully cleared following a 13‐day course of gentamicin lock therapy and intravenous piperacillin–tazobactam, after which the catheter was removed.…”
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Sekwencjonowanie genomu/eksomu człowieka - aspekt bioetyczny
Published 2014-03-01“…The technological breakdown in molecular genetics relies on the change of perspective from the analysis of a single gene to the whole genome sequencing (WGS) or whole-exome sequencing (WES). …”
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Introduction to International Ethical Standards Related to Genetics and Genomics
Published 2013-12-01“…After that, the morality of one recent event related to whole-genome sequencing and person-identifiable genetic data will be explored based on those international standards.…”
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The high cancer incidence in young people in Italy: do genetic signatures reveal their environmental causes?
Published 2016-03-01“…Connecting links amongst the external environment, cellular microenvironment and functional epigenetic and genetic mutations promote carcinogenesis. Today, the whole genome sequencing techniques for human cancers can help to formulate a map of mutational signatures in individual tumours, and a list of mutational fingerprints showing exposure to specific environmental mutagens is being developed. …”
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Colistin Resistance and Management of Drug Resistant Infections
Published 2022-01-01“…Researchers focus on the most advanced genomics (whole genome sequencing), proteomics, and bioinformatics approaches to explore the question of colistin resistance. …”
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Prospective clinical performance of CoVarScan in identifying SARS-CoV-2 Omicron subvariants
Published 2025-01-01“…Conventionally, whole-genome sequencing (WGS) has characterized new SARS-CoV-2 variants, but results come too late for clinical actionability. …”
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