Influencing factors of IgA nephropathy combined with hyperuricemia and a nomogram to predict the risk of hyperuricemia in IgA nephropathy patients by Zhou Jie, Xian Wei-ying, Li Ji-tian, Zeng Jin-cheng

“…There were significant differences in the male proportion （65.82% vs 47.40%）， body mass index ［BMI， （24.67 ± 4.52）kg/m2 vs （22.28 ± 3.17）kg/m2］， hypertension （43.04% vs 23.38%）， triglyceride ［TG， （2.16 ± 0.61）mmol/L vs （1.72 ± 0.30）mmol/L］， white blood cell count ［WBC， （7.28 ± 2.06）×109L vs （5.75 ± 1.52）×109L］， estimated glomerular filtration rate ［eGFR，（66.93 ± 19.85）mL·min-1·（1.73 m2）-1 vs （86.42 ± 22.37）mL·min-1·（1.73 m2）-1］ and IgA/C3 ［（3.07 ± 0.96） vs （2.35 ± 0.62）］ between HUA group and non-HUA group （P<0.05）. …”
Get full text

An aggregation-induced emission-active lysosome hijacker: Sabotaging lysosomes to boost photodynamic therapy efficacy and conquer tumor therapeutic resistance by Hang Zou, Pingping Wang, Zhihao Bai, Liping Liu, Jingtong Wang, Yanfang Cheng, Bairong He, Zujin Zhao, Lei Zheng

“…Furthermore, QM-DMAC effectively generates reactive oxygen species (ROS) under white light irradiation, which precisely induces ROS-mediated lysosomal membrane permeabilization (LMP) and lysosome rupture. …”
Get full text

Prenatal light exposure affects diurnal rhythms and visual development of the layer embryonic retina by S.Q. Wei, P. Yin, W.Y. Tang, Z.Y. Zhang, W. Chu, Q. Tong, B.M. Li, W.C. Zheng, C.Y. Wang

“…Layer eggs (Jingfen No.6) were subjected to white light (5000K, WL) and green light (520 nm/515-525 nm, GL) with a 12L:12D photoperiod throughout the entire incubation period, in contrast to no light incubation (NL). …”
Get full text

Preclinical development of a standardized extract of Ilex paraguariensis A.St.-Hil for the treatment of obesity and metabolic syndrome by Sara E.L. Tolouei, Rodrigo Marcon, Fabiana Cardoso Vilela, Cristina Setim Freitas, Melina Heller, Edineia Lemos de Andrade, Sergio José Macedo Júnior, Adara Áurea dos Santos, Ruth Fernandes Rocha, Guilherme Pasetto Fadanni, Naiani Ferreira Marques, Jarbas Mota Siqueira Júnior, João B. Calixto

“…The mechanisms through which TI-076 acts seem to involve the modulation of several genes associated with inflammation (Il1b, Nlrp3, Pparα and Pparγ), white adipose and liver metabolism (Cartpt, Mgll, Ramp3, Faah, Cck, Clps, Pparα and Pparγ), liver damage and fibrosis (Creb1, Col1a1 and Col3a1). …”
Get full text

Case report: Atypical young case of MV1 Creutzfeldt-Jakob disease with unusually long survival by Lucie Yeongran Ahn, Mark L. Cohen, Mark L. Cohen, Ignazio Cali, Ignazio Cali, Tia Russell, Jessica Ludwig, Xun Jia, Alberto Bizzi, Lawrence B. Schonberger, Ryan A. Maddox, Rohini Paul, Tania C. Ghazarian, Jaspreet Garcha, Mostafa Hammoudi, Brian Stephen Appleby, Brian Stephen Appleby, Brian Stephen Appleby, Brian Stephen Appleby

“…Neuropathologic examination at autopsy revealed severe neuronal loss and gliosis with secondary white matter degeneration but minimal spongiform changes and PrP deposits in the cerebellum and neocortex by immunohistochemistry. …”
Get full text

Kidney Function and Incident Stroke and Dementia Using an Updated Estimated Glomerular Filtration Rate Equation Without Race: The Multi-Ethnic Study of Atherosclerosis by Samuel R. Moen, Jeffrey R. Misialek, Timothy M. Hughes, Craig W. Johnson, Mark J. Sarnak, Sarah N. Forrester, W.T. Longstreth, Jr., Mercedes R. Carnethon, James S. Pankow, Sanaz Sedaghat

“…The analytic sample consisted of 6,646 participants (mean [SD] age 62 [10] years; 53% female; 39% White, 27% African American, 12% Chinese American, and 22% Hispanic/Latino). …”
Get full text

Low error floor LT coding algorithm for unequal error protection by Xin SONG, Shuyan NI, Zhe ZHANG, Yurong LIAO, Tuofeng LEI

“…As the first achievable rateless code,the rateless LT code can be conveniently used in conjunction with the UEP algorithm to realize adaptive data transmission.However,the conventional UEP-LT code algorithm has problems such as high error floor and poor convergence performance in the additive white Gaussian noise(AWGN)channel.Therefore,an improved systematic UEP-LT coding scheme is designed in this paper. …”
Get full text

The potential of bacteriophage for controlling Vibrio parahaemolyticus as in-vitro by Bagus Ansani Takwin, Dinamella Wahjuningrum, Widanarni Widanarni, Hasan Nasrullah

“… Vibrio parahaemolyticus infection is a major threat to Pacific white shrimp aquaculture, causing significant shrimp mortality. …”
Get full text

Utilization of patient-reported outcomes to assess adherence to relugolix when combined with stereotactic body radiation therapy for intermediate to high-risk prostate cancer by Kelly Gaudian, Min Jung Koh, Min Ji Koh, Ryan R. Collins, Shaine Eden, Zoya Zwart, Malika Danner, Alan Zwart, Mark Fallick, Deepak Kumar, Paul Leger, Nancy A. Dawson, Simeng Suy, Sean P. Collins

“…The median age was 72, and 41% of patients were non-white. Patients initiated relugolix at a median of 4 months prior to the SMAQ (2-19 months). 96% of patients achieved castration (≤ 50 ng/dL) at the time of the SMAQ. 96% of men reported always taking relugolix at the appropriate time. 1% discontinued medication due to bothersome side effects, 17% reported forgetting to take the medication, and 4% reported missing a dose during the weekend. 98% and 93% did not miss a dose more than 2 times in the last week and since the last visit, respectively. …”
Get full text

Association between non-insulin-based insulin resistance surrogate makers and Helicobacter pylori infection: a population-based study by Jiayu Qiu, Yueming Yu, Dingwei Liu, Sihai Chen, Youhua Wang, Jianxiang Peng, Jinliang Xie, Chengyun Wu, Feng Zhou, Hui Fang, Qirui Lai, Yong Xie

“…In subgroup analysis, the adjusted association between three IR surrogate markers and H. pylori infection were more likely to be observed in female and Non-Hispanic White. Additionally, the RCS curve revealed a positive linear correlation between TyG index and H. pylori infection across all three models, and between METS-IR and H. pylori infection in Model 3. …”
Get full text

Serum lipid profile in systemic lupus erythematosus by Jingxiu Xuan, Jingxiu Xuan, Jingxiu Xuan, Chaoqiong Deng, Huiqin Lu, Yan He, Yan He, Yan He, Jimin Zhang, Xiaoli Zeng, Xiaoli Zeng, Yuechi Sun, Yuechi Sun, Yuechi Sun, Shiju Chen, Shiju Chen, Shiju Chen, Yuan Liu, Yuan Liu, Yuan Liu

“…TC, TG, and HDL were elevated in patients with SLE and were associated with decreased IgG, increased 24-h proteinuria, white blood cells (WBCs), and neutrophils. Decreased HDL and increased TG were associated with an increase in the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI). …”
Get full text

Exemples d’habitats aristocratiques sur les sites des rues Eugène-Desteuque et Ponsardin à Reims/Durocortorum by Magalie Cavé, Stéphane Sindonino, Sabine Groetembril

“…It would take less than a generation for houses built in perishable materials to be abandoned for the adoption of Roman style construction (e.g. the opus signinum floors decorated with black and white tesserae crosses on rue Eugène-Desteuque). …”
Get full text

Economic burden of breast cancer in India, 2000–2021 and forecast to 2030 by Rakesh N Pillai, Aleena Alex, Narassima M.S., Vivek Verma, Ajil Shaji, Keechilat Pavithran, D. K. Vijaykumar, Denny John

“…The residuals were tested using the Box-Ljung test to confirm the absence of autocorrelation and verify that they followed a white noise distribution. Using the fitted ARIMA model, prevalence rates were forecasted from 2022 to 2030, with 95% confidence intervals to capture prediction uncertainty. …”
Get full text

Kazanç Yönetiminin Kar Dağıtım Politikaları Üzerindeki Etkisi: BİST Sınai Endeksinde Bir Uygulama by Bahadır Uysal, Evren Yanya

“…Model sonuçlarındaki değişen varyans sorunu Huber, Eicker ve White Tahmincisi kullanılarak ortadan kaldırılmıştır. …”
Get full text

Identifying subgroup of severe community-acquired pneumonia based on clinical metagenomics, a multicenter retrospective cohort study by Mingqiang Wang, Mingqiang Wang, Yue Jin, Yue Jin, Wenxiao Zhang, Wenxiao Zhang, Ling Ye, Ling Ye, Huanzhang Shao, Huanzhang Shao

“…Latent class analysis (LCA) was applied to routine clinical parameters such as gender, age, white blood cell (WBC), lymphocytes, C-reactive protein (CRP), and Procalcitonin (PCT), identifying two optimally fitting models.ResultsA total of 569 patients were enrolled. …”
Get full text

Enzymic Activity, Metabolites, and Hematological Responses Changes of Clinical Healthy High-Risk Beef Calves During Their First 56-Days from Arrival by Octavio Carrillo-Muro, Pedro Hernández-Briano, Paola Isaira Correa-Aguado, Alejandro Rivera-Villegas, Oliver Yaotzin Sánchez-Barbosa, Rosalba Lazalde-Cruz, Alberto Barreras, Alejandro Plascencia, Daniel Rodríguez-Cordero

“…The following parameters were determined: total white blood cells (WBC): lymphocytes (LYM), lymphocytes % (LYM%), monocytes (MON), monocytes % (MON%), granulocytes (GRA), granulocytes % (GRA%), platelets (PLT), and mean platelet volume (MPV); red blood cells (RBC): red blood cell distribution width test % (RDW%), hematocrit (HCT), and mean corpuscular volume (MCV); hemoglobin (HGB): mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC). …”
Get full text

Comparative Analysis of the Enzymatic, Coagulant, and Neuromuscular Activities of Two Variants of <i>Crotalus durissus ruruima</i> Venom and Antivenom Efficacy by Poliana J. Demico, Isabele N. Oliveira, Vitória S. Proença-Hirata, Samuel R. Dias, Hugo A. Ghirotti, Elisangela O. Silva, Inês C. Giometti, Francis L. Pacagnelli, Kristian A. Torres-Bonilla, Stephen Hyslop, Nathália C. Galizio, Karen de Morais-Zani, Manuela B. Pucca, Anderson M. Rocha, Jéssica B. Maciel, Marco A. Sartim, Wuelton M. Monteiro, Rafael S. Floriano

“…<b>Background:</b> We compared the enzymatic, coagulant, and neuromuscular activities of two variants (yellow—CDRy and white—CDRw) of <i>Crotalus durissus ruruima</i> venom with a sample of <i>C. d. terrificus</i> (CDT) venom and examined their neutralization by antivenom against CDT venom. …”
Get full text

Middle-age cerebral small vessel disease and cognitive function in later life: a population-based prospective cohort studyResearch in context by Ali Tanweer Siddiquee, Yoon Ho Hwang, Soriul Kim, Sung Jin Shin, Ji Soo Lee, June Christoph Kang, Min-Hee Lee, Hyeon Jin Kim, Seung Ku Lee, Chol Shin

“…SVD was defined by the presence of any of the visible MRI markers (age-related white matter change, lacunes and cerebral microbleeds) at baseline. …”
Get full text

Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder by Itay Tokatly Latzer, Jean-Baptiste Roullet, Wardiya Afshar-Saber, Henry H. C. Lee, Mariarita Bertoldi, Gabrielle E. McGinty, Melissa L. DiBacco, Erland Arning, Melissa Tsuboyama, Alexander Rotenberg, Thomas Opladen, Kathrin Jeltsch, Àngels García-Cazorla, Natalia Juliá-Palacios, K. Michael Gibson, Mustafa Sahin, Phillip L. Pearl

Get full text

Ambient air pollution exposure in relation to cerebral small vessel disease in Chinese population: A cranial magnetic resonance imaging-based study by Yudiyang Ma, Ying Hui, Linxi Tang, Jianing Wang, Meiqi Xing, Lei Zheng, Feipeng Cui, Shuohua Chen, Shouling Wu, Zhenchang Wang, Yaohua Tian

“…For each interquartile range increase in air pollutant exposure during the examination year, the odds ratios and 95% confidence intervals of the increased white matter hyperintensity burden were 1.45 (1.15, 1.84) for PM2.5, 1.72 (1.27, 2.34) for PM10, 1.26 (1.05, 1.51) for SO2, 1.52 (1.16, 2.00) for NO2, and 1.63 (1.26, 2.13) for CO. …”
Get full text