Combining Microarray Technology and Molecular Epidemiology to Identify Genes Associated with Invasive Group B Streptococcus by Lixin Zhang, Usha Reddi, Usha Srinivasan, Sheng Li, Stephanie M. Borchardt, Parvathy Pillai, Puja Mehta, Anne N. Styka, Joan DeBusscher, Carl F. Marrs, Betsy Foxman

“…Many bacterial species function as both commensals and pathogens; we used this dual nature to develop a high-throughput molecular epidemiological approach to identifying bacterial virulence genes. We applied our approach to Group B Streptococcus (GBS). …”
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A comprehensive review of mycoviruses infecting the plant pathogenic fungus Rosellinia necatrix by Sidra Hassan, Robert H. A. Coutts, Atif Jamal, Ioly Kotta-Loizou, Ioly Kotta-Loizou

“…This article provides a comprehensive overview of mycoviruses infecting plant pathogenic fungus Rosellinia necatrix causing white root rot, including the prevalence of their occurrence, their taxonomic classification, their genomic organization and structure, impacts on their fungal host in terms of phenotype in general and virulence in particular, and their ecological interactions including transmission. …”
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Overview of Community-Acquired Pneumonia and the Role of Inflammatory Mechanisms in the Immunopathogenesis of Severe Pneumococcal Disease by Helen C. Steel, Riana Cockeran, Ronald Anderson, Charles Feldman

“…Thereafter, the review is focused on the pneumococcus, specifically the major virulence factors of this microbial pathogen and their role in triggering overexuberant inflammatory responses which contribute to the immunopathogenesis of invasive disease. …”
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Metformin: A Potential Drug for COVID-19 by Anjali Devi Bettadapura Shankara Rao, Sujatha Puttalingaiah, Ananth B Koushik, Jadeppa Gowda

“…Its varied actions on coronavirus infections, by inhibiting virus entry, preventing cytokine storm, boosting immunity by altering the gut microbiota, and decreasing virulence by inducing autophagy makes it an ideal candidate for treating coronavirus disease-2019 (COVID-19). …”
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N-Acetylglucosamine Functions in Cell Signaling by James B. Konopka

“…For example, GlcNAc stimulates the human fungal pathogen Candida albicans to undergo changes in morphogenesis and expression of virulence genes. Pathogenic E. coli responds to GlcNAc by altering the expression of fimbriae and CURLI fibers that promote biofilm formation and GlcNAc stimulates soil bacteria to undergo changes in morphogenesis and production of antibiotics. …”
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Antimicrobial Activities of Stigmasterol from Piper crocatum In Vitro and In Silico by Seftiana Lestari, Dikdik Kurnia, Tri Mayanti, Leny Heliawati

“…However, the proteins precisely inhibited by stigmasterol compounds have not been identified as target proteins in the mechanism of action of stigmasterol as an oral antimicrobial agent or proteins involved in the virulence system of pathogenic oral microorganisms. …”
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Streptokinase is dispensable in Streptococcus dysgalactiae subspecies equisimilis infections of human dendritic cells by Katharina E. Folz, Nikolai Siemens

“…Abstract In recent years, increased numbers of severe Streptococcus dysgalactiae subsp. equisimilis (SDSE) infections, including necrotizing soft tissue infections (NSTIs), have been reported. One of the main virulence factors of SDSE is streptokinase (Ska). Ska promotes bacterial spread in the tissue through Ska-plasminogen interactions and subsequent activation of plasminogen to plasmin. …”
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African swine fever: one hundred years later by V. V. Makarov

“…In addition to the gaps mentioned in these conclusions and recommendations there are serious gaps in African swine fever immunology, namely in protective immunity mechanisms, virus-macrophage interaction, in vitro virus phenotypic  signs correlating with its virulence, etc. Evidently, it is hardly possible to expect development of anti-ASF vaccines and particularly the vaccines capable of preventing and effectively protecting against ASF epizooty according to the general understanding without addressing these issues.…”
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Molecular detection of pore-forming leuko toxin in methicillin resistant Staphylococcus aureus isolated from skin infection by Sara A. Al-Ghazal, Huda H. Al-Hassnawi

“…Abstract Background: The ability of Staphylococcus aureus to cause disease has been attributed to an impressive spectrum of virulence factors. Objective: The study investigated molecular detection of pore-forming leuko toxin (Panton–Valentine leucocidin [PVL]) in S. aureus that is resistant to methicillin (MRSA) isolated from skin infections. …”
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Metabolomic analysis of murine tissues infected with Brucella melitensis. by Bárbara Ponzilacqua-Silva, Alexis S Dadelahi, Charles R Moley, Mostafa F N Abushahba, Jerod A Skyberg

“…Treatment of macrophages with GABA did not alter control of B. melitensis infection, and deletion of the putative GABA transporter BMEI0265 did not alter B. melitensis virulence. While glutaminolysis inhibition did not affect control of B. melitensis in macrophages, glutaminolysis was required for macrophage IL-1β production in response to B. melitensis. …”
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Gene Expression during Survival of Escherichia coli O157:H7 in Soil and Water by Ashley D. Duffitt, Robert T. Reber, Andrew Whipple, Christian Chauret

“…Cells incubated in soil microcosms for 14 days expressed genes for antibiotic resistance, biosynthesis, DNA replication and modification, metabolism, phages, transposons, plasmids, pathogenesis and virulence, antibiotic resistance, ribosomal proteins, the stress response, transcription, translation, and transport and binding proteins at significantly higher levels than cells grown in Luria broth. …”
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Type III Secretion System in Intestinal Pathogens and Metabolic Diseases by Le Zhou, Yaoyuan Zhang, Shiqi Wu, Yiyu Kuang, Pengfei Jiang, Xiao Zhu, Kai Yin

“…Although the T3SS is critical for the virulence of many important human pathogens, its relationship with metabolic diseases remains unknown. …”
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Insights from a Genome-Wide Study of <i>Pantoea agglomerans</i> UADEC20: A Promising Strain for Phosphate Solubilization and Exopolysaccharides Production by Edith Elizondo-Reyna, Humberto Martínez-Montoya, Yahaira Tamayo-Ordoñez, María Antonia Cruz-Hernández, Mauricio Carrillo-Tripp, María Concepción Tamayo-Ordoñez, Gerardo de Jesús Sosa-Santillán, José Antonio Rodríguez-de la Garza, Mario Hernández-Guzmán, Virgilio Bocanegra-García, Erika Acosta-Cruz

“…The comprehensive set of genes supporting phosphate solubilization, EPS synthesis, and secretion, along with its low virulence and antibiotic resistance levels, justify further research for its potential biotechnological application and possible use as a plant growth-promoting agent in the field. …”
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Antimicrobial potential and mechanism of infant feces-derived Enterococcus faecalis in inhibiting Enterotoxigenic Escherichia coli by Xi Lu, Wei Sang, Lei Pan

“…E. faecalis LX25 and LX39 showed significant inhibition of ETEC growth, virulence gene (eltA and stA) expression (P < 0.05) and disrupted biofilm formation. …”
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Host-Bacteria Crosstalk at the Dentogingival Junction by M. T. Pöllänen, M. A. Laine, R. Ihalin, V.-J. Uitto

“…Furthermore, not only the shift of the bacterial flora to a more pathogenic one, but also bacterial growth as a biofilm on the tooth surface, allows the bacteria to communicate with each other and exert their virulence aimed at favoring their growth. This paper focuses on host-bacteria crosstalk at the dentogingival junction and the models studying it in vitro.…”
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Association between microplastics and the functionalities of human gut microbiome by Bei Gao, Lixia Chen, Lizhi Wu, Shirui Zhang, Sunan Zhao, Zhe Mo, Zhijian Chen, Pengcheng Tu

“…Associations were found between microplastics and microbial species, as well as microbial genes encoding invasion-related virulence factors, quorum sensing, autoinducer and transporter system, and microplastic biodegradation enzymes. …”
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The Fem cell-surface signaling system is regulated by ExsA in Pseudomonas aeruginosa and affects pathogenicity by Yanqi Li, Anjali Bhagirath, Sara Badr, Pansong Zhang, Lin Chen, Maryam Dadashi, Michael G. Surette, Kangmin Duan

“…Intriguingly, the Fem system also influenced virulence factors in P. aeruginosa, including the quorum sensing systems, pyocyanin production, biofilm formation, and the type six secretion systems (T6SSs). …”
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Pathogenic potential of ornithogenic <i>Escherichia coli</i> strains detected in the Earth's polar regions by Batyrbek I. Aslanov, Daniil V. Azarov, Maria A. Makarova, Elizaveta G. Marysheva, Lyudmila A. Kraeva, Aleksey S. Mokhov, Ekaterina A. Lebedeva, Nikita E. Goncharov, Natalya V. Lebedeva, Dmitry A. Starikov, Victoria V. Kolodzhieva, Dmitry E. Polev, Artemy E. Goncharov

“…All strains studied were characterized by the presence of extensive virulence. Among the pathogenicity factors identified were haemolysins A, E, F, siderophores, including the yersiniabactin gene cluster, a number of adhesion, colonization and invasion factors, as well as the thermostable enterotoxin EAST-1 and genes that characterize enteroaggregative strains of E. coli (the virulence regulator gene eilA and enteroaggregative protein (air)). …”
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Shared mechanisms of enhanced plasmid maintenance and antibiotic tolerance mediated by the VapBC toxin:antitoxin system by Sarah Hollingshead, Gareth McVicker, Maria R. Nielsen, YuGeng Zhang, Giulia Pilla, Rebekah A. Jones, Jonathan C. Thomas, Sarah E. H. Johansen, Rachel M. Exley, Ditlev E. Brodersen, Christoph M. Tang

“…Here, we identified a clinical isolate of Shigella sonnei (CS14) with a remarkably stable pINV virulence plasmid; pINV is usually frequently lost from S. sonnei, but plasmid loss was not detected from CS14. …”
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Isolation, Identification, and Resistance Test of Escherichia coli to Antibiotics in Ujung Berung Broiler Poultry by Fatia Nasyna Afifa Kantamaryana, Roostita L Balia, Wendry Setiyadi Putranto

“…Escherichia coli is commensal bacteria in the intestinal of broiler chickens with low virulence. However, mostly pathogenic and cause colibacillosis illness. …”
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