Genome Assembly and Genome Annotation of Leishmania martiniquensis Isolated from a Leishmaniasis Patient in Thailand by Songtham Anuntakarun, Atchara Phumee, Vorthon Sawaswong, Kesmanee Praianantathavorn, Witthaya Poomipak, Rungrat Jitvaropas, Padet Siriyasatien, Sunchai Payungporn

“…The total number of open reading frames genomewide predicts 8,209 protein-coding genes, of which 359 are putative virulence factors, including two previously known, e.g., cysteine proteinase C and superoxide dismutase B1. …”
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<i>Pseudomonas aeruginosa pqs</i> Quorum Sensing Mediates Interaction with <i>Mycobacterium abscessus</i> In Vitro by Yun Long, Zhi Li, Menglu Li, Peiyi Lu, Yujia Deng, Pengyao Wu, Xue Li, Gangjian Qin, Jiamin Huang, Wenying Gao, Guobao Li, Tianyuan Jia, Liang Yang

“…Our study suggests that the <i>P. aeruginosa</i> PQS can serve as an interspecies signaling molecule to communicate with <i>Mycobacterium</i> and affect their physiology and virulence.…”
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Streptococcus suis-associated neonatal meningitis and sepsis: characterization, antimicrobial resistance, and public health implications by Giovanna Fusco, Rubina Paradiso, Lorena Cardillo, Maria Antonia Salvia, Saveria Dodaro, Veronica Del Monaco, Gianfranco Scarpelli, Francesca Greco, Antonio Rinaldi, Lorella Barca, Stefania Ambrogio, Antonio Limone, Esterina De Carlo, Giorgia Borriello

“…Next-generation sequencing revealed that the strain was serotype 2 sequence type 1, and contained the ermB and tet(W) genes, which are responsible for resistance to macrolides and tetracycline, along with several pilus-associated genes and 20 virulence factors. High homology was observed with previously identified human and swine strains in the same area. …”
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Effects of Environmental Temperature on the Dynamics of Ichthyophoniasis in Juvenile Pacific Herring (Clupea pallasii) by Jake L. Gregg, Johanna J. Vollenweider, Courtney A. Grady, Ron A. Heintz, Paul K. Hershberger

“…In addition to defining parameters for a herring bioenergetics model (discussed in Vollenweider et al. this issue), these experiments provided new insights into factors influencing the infectivity and virulence of the parasite Ichthyophonus. In groups of fish with established disease, temperature variation had little effect on disease outcome. …”
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Potential Usefulness of Streptococcus pneumoniae Extracellular Membrane Vesicles as Antibacterial Vaccines by Chi-Won Choi, Edmond Changkyun Park, Sung Ho Yun, Sang-Yeop Lee, Seung Il Kim, Gun-Hwa Kim

“…The EMVs of bacteria play important roles in their virulence, biogenesis mechanisms, and host cell interactions. …”
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The palmitoyl-CoA ligase Fum16 is part of a Fusarium verticillioides fumonisin subcluster involved in self-protection by Fabio Gherlone, Katarina Jojić, Ying Huang, Sandra Hoefgen, Vito Valiante, Slavica Janevska

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Salmonella pathogenicity Island 1 undergoes decay in serovars adapted to swine and poultry by Martina Tambassi, Melissa Berni, Chiara Bracchi, Ilaria Menozzi, Alessandra Dodi, Laura Mazzera, Marina Morganti, Erika Scaltriti, Stefano Pongolini

“…On the other side, the study provides scientific background for reconsidering the microbiological criteria adopted by the food safety legislation of many countries that ask for the absence of Salmonella in foods, regardless of any virulence evaluation of the detected strain. In this respect, the study provides molecular bases to investigate the virulence of different lineages within these host-adapted serovars.…”
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A bacterial type III effector hijacks plant ubiquitin proteases to evade degradation. by Wenjia Yu, Meng Li, Wenjun Wang, Haiyan Zhuang, Jiamin Luo, Yuying Sang, Cecile Segonzac, Alberto P Macho

“…Despite the fact that bacterial effectors are exogenous threatening proteins potentially exposed to the protein degradation systems inside plant cells, effectors are relative stable and able to perform their virulence functions. In this work, we found that RipE1, an effector protein secreted by the bacterial wilt pathogen, Ralstonia solanacearum, undergoes phosphorylation of specific residues inside plant cells, and this promotes its stability. …”
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Développement de résistances chez les animaux alors que l’antibiotique ne leur a pas été administré by Madec, Jean-Yves

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The Potential of Secondary Metabolites in Medicinal Plants as Anti–Quorum Sensing in Biofilms: A Comprehensive Review by Salsabila Aqila Putri, Euis Julaeha, Natsuko Kagawa, Dikdik Kurnia

“…Quorum sensing plays a role for competition, virulence, resistance, and pathogenesis. Quorum sensing produces signaling response called as autoinducers. …”
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Mercury Intrusion Effects Modelled in Pores with Axial Symmetry and Attenuated Cross Section by Isaac Kornhauser, Carlos Felipe, Juan Marcos Esparza, Armando Domínguez, Fernando Rojas

“…Virtual penetration curves indicate Laplace stable or unstable states as well as the virulence of the irreversible penetration of pores with a varying cross section. …”
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Edible plant Artemisia argyi H.Lév. &amp; Vaniot: An in vitro study on its anti-Helicobacter pylori effect by Meiyun Chen, Sheng Pan, Fengli Lin, Weixing Zhu, Baojie Li, Bing Zhou, Guimin Zhang, Zhong Feng, Meicun Yao

“…It demonstrated no antagonistic effects when combined with antibiotics and disrupted H. pylori morphology and structure, downregulated various virulence genes, and inhibited urease activity. In co-culture systems, A. argyi reduced H. pylori adhesion, urease levels, and NO production, indicating immunomodulatory activity. …”
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Origin and pathogenicity variation of Plasmopara viticola in China by Wei Wu, Wei Wu, Yuchen Chen, Huimin Huang, Rongfang Li, Bohan Yang, Junli Lv, Ling Yin, Ling Yin, Junjie Qu, Shiren Song, Yachun Peng, Peining Fu, Jiang Lu

“…Analyses of the interactions between Pv isolates and grapevines reveal that the virulence of Pv isolates is correlated with the occurrence time and magnitude of hypersensitive response-mediating leaf necrosis in grape leaves caused by Pv. …”
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Water pollution, cholera, and the role of probiotics: a comprehensive review in relation to public health in Bangladesh by Md. Rayhan Chowdhury, Ariful Islam, Valentina Yurina, Takeshi Shimosato, Takeshi Shimosato, Takeshi Shimosato

“…Recent probiotic advancements include engineering strains that disrupt V. cholerae biofilms and inhibit their virulence. Integrating probiotics with traditional cholera control measures could significantly enhance their effectiveness and provide a multifaceted approach to combating this persistent disease. …”
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Systematic surveillance of SARS-CoV-2 reveals dynamics of variant mutagenesis and transmission in a large urban population by Marie-Ming Aynaud, Lauren Caldwell, Khalid N. Al-Zahrani, Seda Barutcu, Kin Chan, Andreea Obersterescu, Abiodun A. Ogunjimi, Min Jin, Kathleen-Rose Zakoor, Shyam Patel, Ron Padilla, Mark C. C. Jen, Princess Mae Veniegas, Nursrin Dewsi, Filiam Yonathan, Lucy Zhang, Amelia Ayson-Fortunato, Analiza Aquino, Paul Krzyzanowski, Jared Simpson, John Bartlett, Ilinca Lungu, Bradly G. Wouters, James M. Rini, Michael Gekas, Susan Poutanen, Laurence Pelletier, Tony Mazzulli, Jeffrey L. Wrana

“…Abstract Highly mutable pathogens generate viral diversity that impacts virulence, transmissibility, treatment, and thwarts acquired immunity. …”
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Convergent evolution of oxidized sugar metabolism in commensal and pathogenic microbes in the inflamed gut by Sophia Levy, Angela K. Jiang, Maggie R. Grant, Gabriela Arp, Glory Minabou Ndjite, Xiaofang Jiang, Brantley Hall

“…Previously considered a pathogen virulence factor, oxidized sugar metabolism is also present in specific commensals and may contribute to their increased relative abundance in gastrointestinal inflammation.…”
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Within-host evolution of a transcriptional regulator contributes to the establishment of chronic Pseudomonas aeruginosa infection by Ning Zhou, Jingchen Yu, Xujiao Liu, Chengxi Li, Huang Tang, Lin Lyu, Chengwei Wu, Yana Chen, Jian Zhang, Jinjing Ni, Danni Wang, Jing Tao, Wenjuan Wu, Yu Zhang, Yun Feng, Yanjie Chao, Jie Lu, Ping He, Yu-Feng Yao

“…Overall, the mutation in gavR attenuates P. aeruginosa virulence and enhances innate immune evasion by reprogramming pyruvate metabolism and the glyoxylate cycle. …”
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Potential use of peptides mimicking CRAC/CARC domains as antivirulence therapies to inhibit RTX toxins activities by Vanesa Herlax

“…These efforts focus on inhibiting the virulence factors bacteria secrete to proliferate. …”
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Aspergillus fumigatus ctf1–a novel zinc finger transcription factor involved in azole resistance by Xiao Gong, Heng Zhang, Wenxu Cheng, Zhangxuan He, Tianyan Ma, Tian Chen, Yi Sun

“…Thus, our results on the function of ctf1 contribute to the elucidation of the mechanisms underlying A. fumigatus resistance and the factors associated with A. fumigatus virulence.…”
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Helicobacter pylori CagA promotes gastric cancer immune escape by upregulating SQLE by Sifan Liu, Nan Zhang, Xu Ji, Shuyue Yang, Zheng Zhao, Peng Li

“…Abstract Helicobacter pylori (H. pylori) infection is a well-established risk factor for gastric cancer, primarily due to its virulence factor, cytotoxin-associated gene A (CagA). …”
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