Recurrent Multivalvular Staphylococcus Lugdunensis Endocarditis Causing Complete Heart Block after TAVR by Preeti Singhal, Somsupha Kanjanauthai, Wilson Kwan

“…Staphylococcus lugdunensis is an unusual but virulent organism that may damage both native and prosthetic valves. …”
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A Rare Case of Proximal Junctional Failure with Delayed Infection after Adult Spinal Deformity Surgery: A Report of Two Cases by Takuro Iwami, Mitsuru Yagi, Eijiro Okada, Satoshi Suzuki, Satoshi Nori, Osahiko Tsuji, Narihito Nagoshi, Kota Watanabe, Nobuyuki Fujita, Masaya Nakamura, Morio Matsumoto

“…Since the delayed infections developed not in the fused segments but in the adjacent vertebra, the cause of the first case can be speculated as stimulation of low-virulent organisms to fester and hematogenous seeding and that of the second case as metal fretting and a sterile inflammatory response causing hematogenous microbial seeding, respectively. …”
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In-silico formulation of a next-generation polyvalent vaccine against multiple strains of monkeypox virus and other related poxviruses. by Abu Tayab Moin, Nurul Amin Rani, Rajesh B Patil, Tanjin Barketullah Robin, Md Asad Ullah, Zahidur Rahim, Md Foyzur Rahman, Talha Zubair, Mohabbat Hossain, A K M Moniruzzaman Mollah, Nurul Absar, Mahboob Hossain, Mohammed Abul Manchur, Nazneen Naher Islam

“…This study utilized a reverse vaccinology approach to retrieve conserved epitopes for monkeypox virus and construct a vaccine that could provide cross-protection against related viruses with similar antigenic properties. The selected virulent proteins of monkeypox virus, MPXVgp165, and Virion core protein P4a, were subjected to epitope mapping for vaccine construction. …”
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Homeopathic Treatment of Arabidopsis thaliana Plants Infected with Pseudomonas syringae by Devika Shah-Rossi, Peter Heusser, Stephan Baumgartner

“…We investigated the potential of a common plant-pathogen system, Arabidopsis thaliana infected with the virulent bacteria Pseudomonas syringae, regarding its response towards a homeopathic treatment. …”
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Implication of Cytotoxic Helicobacter pylori Infection in Autoimmune Diabetes by Alessandro P. Delitala, Giovanni M. Pes, Hoda M. Malaty, Gavino Pisanu, Giuseppe Delitala, Maria P. Dore

“…Although H. pylori seroprevalence was similar in LADA, T1D, and T2D, anti-CagA positivity was significantly increased among patients with autoimmune diabetes, suggesting that more virulent H. pylori strains might be a trigger for immune mechanisms involved in their pathogenesis.…”
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LysR-Type Transcriptional Regulator VirR Responds to Temperature and pH and Directly Activates the Transcription of virS-Containing Operon in Rhodococcus equi by Tsutomu Kakuda, Takashi Sato, Mari Takuhara, Hirofumi Hagiuda, Yasunori Suzuki

“…Rhodococcus equi—a facultative intracellular pathogen of macrophages—causes bronchopneumonia in foals and patients who are immunocompromised. Virulent strains of R. equi possess a virulence-associated plasmid, which encodes a 15- to 17-kDa surface protein called virulence-associated protein A (VapA). …”
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Association of haplotypes for SNPs in the LTR regions of bovine leukemia virus with hematological indices of cattle by N. V. Blazhko, S. Kh. Vyshegurov, A. S. Donchenko, K. S. Shatokhin, T. I. Krytsyna, V. A. Ryabinina

“…In this connection, an assumption was made about the evolutionary advantage of the more virulent haplotype III. However, the results of our own research in conjunction with the data of other scientists indicate that the high virulence of individual virus strains is a consequence of the tendency to implement the maximum possible intensity of the synthesis of virus particles but not of the high damaging effect alone. …”
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ANTIGENIC AND PROTECTIVE PROPERTIES OF ASSOCIATED VIRUS VACCINE AGAINST SHEEP POX, GOAT POX AND PESTE DES PETITS RUMINANTS by A. V. Konstantinov, S. K. Starov, V. I. Diev, N. V. Moroz, E. V. Kurnenkova, D. K. Basova, A. V. Kononov, K. Yu. Fedoseyev, V. P. Melnikov

“…The vaccination induced high level of virus neutralizing antibodies against each of the above listed diseases and ensured formation of strong immunity tat is supported by the results of tallenge of sheep with virulent sheep pox virus (“Afghanistan” strain). In 14 and 21 days in blood of sheep immunized with the virus vaccine against sheep pox, goat pox and peste des petits rum^nts titres of antibodies against sheep pox virus ((4.17±0.12)-(4.84±0.31)) and PPR ((5.92±0.23)-(6.08±0.23)) were higher as compared to goat pox antibody titres ((1.99±0.89)-(3.53±0.58) log2). …”
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Isolation, Characterization, and Identification of Biological Control Agent for Potato Soft Rot in Bangladesh by M. M. Rahman, M. E. Ali, A. A. Khan, A. M. Akanda, Md. Kamal Uddin, U. Hashim, S. B. Abd Hamid

“…Antibacterial activity of the isolated probable antagonistic bacteria was tested in vitro against the previously identified most common and most virulent soft rot causing bacterial strain Ecc P-138. …”
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Different Transcriptional Profiles of Human Monocyte-Derived Dendritic Cells Infected with Distinct Strains of Mycobacterium tuberculosis and Mycobacterium bovis Bacillus Calmette-... by Nunzia Sanarico, Alessia Colone, Manuela Grassi, Viviana Speranza, Daniela Giovannini, Antonio Ciaramella, Vittorio Colizzi, Francesca Mariani

“…In order to analyze dendritic cells (DCs) activation following infection with different mycobacterial strains, we studied the expression profiles of 165 genes of human monocyte-derived DCs infected with H37Rv, a virulent Mycobacterium tuberculosis (MTB) laboratory strain, CMT97, a clinical MTB isolate, Mycobacterium bovis bacillus Calmette-Guérin (BCG), Aventis Pasteur, and BCG Japan, both employed as vaccine against tuberculosis. …”
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ANTIGENIC AND PROTECTIVE PROPERTIES OF EXPERIMENTAL ASSOCIATED VIRUS VACCINE AGAINST SHEEP POX AND GOAT POX by A. V. Konstantinov, S. K. Starov, V. I. Diev, N. V. Moroz, E. V. Kurnenkova, D. К. Basova, А. V. Kononov, K. Yu. Fedoseyev

“…All sheep immunized with the monovalent vaccine against sheep and goat pox and associated virus vaccines, resisted the disease when challenged with a virulent sheep pox virus “Afghanistan” strain. Three sheep vaccinated with a monovalent vaccine against goat pox demonstrated a large local reaction, one sheep was diagnosed with generalized form of sheep pox.…”
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Toxin and capsule production by Bacillus cereus biovar anthracis influence pathogenicity in macrophages and animal models. by Treenate Jiranantasak, Andrew P Bluhm, Donald J Chabot, Arthur Friedlander, Richard Bowen, Ian A McMillan, Ted L Hadfield, Airn Hartwig, Jason K Blackburn, Michael H Norris

“…Our research demonstrated that Bcbva is more virulent than B. anthracis Ames using two in vivo models, Galleria mellonella larvae and guinea pigs. …”
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Field apple scab susceptibility of a diverse Malus germplasm collection identifies potential sources of resistance for apple breeding by David Papp, Liqiang Gao, Ranjita Thapa, Dan Olmstead, Awais Khan

“…We also screened a differential host set for 2 years to monitor for changes in the effectiveness of ten known scab resistance genes, which allowed us to confirm the presence of virulent pathogen races in the orchard. Results We found that ~ 37% of the wild Malus accessions and domesticated cultivars were resistant to apple scab in the field. …”
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Properties of Actinobacillus pleuropneumoniae isolates by V. А. Evgrafova, О. V. Pruntova, N. B. Shadrova, А. М. Timina

“…Isolate No. 4 belonging to serotype 5 was found to be the most virulent out of tested isolates. Thus, LD50 was 4.19 lg microbial cells for white mice and 5.49 lg microbial cells for piglets that was consistent to the data of other authors carried out tests of actinobaccilli isolated in the Russian Federation for their pathogenicity. …”
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Characterization of infectious salmon anaemia virus survival and infectivity in seawater by Simon Chioma Weli, Marit Måsøy Amundsen, Ole Bendik Dale, Sonal Jayesh Patel

“…Infectious salmon anaemia virus (ISAV) is a water-borne virus that cause infectious salmon anaemia in Atlantic salmon. Virulent ISAV primarily infects salmon and replicates within salmon, which then shed virus particles potentially infecting naïve salmon. …”
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The Distribution of Cytotoxic Necrotizing Factors (CNF-1, CNF-2, CNF-3) and Cytolethal Distending Toxins (CDT-1, CDT-2, CDT-3, CDT-4) in Escherichia coli Isolates Isolated from Ext... by Cansu Onlen Guneri, Fatih Koksal, Suna Kizilyildirim, Basak Bedir, Togrul Nagiyev

“…Results. At least one virulence gene was present in 156 (24%) of the 646 ExPEC isolates. …”
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Potato resistance to quarantine diseases by A. V. Khiutti, O. Yu. Antonova, N. V. Mironenko, T. A. Gavrilenko, O. S. Afanasenko

“…Cultivation of cultivars poorly susceptible to PGN can stimulate the adaptive variability of the pathogen and induce virulent pathotypes for 2–3 pathogen generations.…”
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ANALYSIS OF CHANGES IN AFRICAN SWINE FEVER VIRUS GENETIC STRUCTURE AND BIOLOGICAL PROPERTIES DURING ADAPTATION TO CONTINUOUS CELL CULTURE by Ali Mazloum, N. G. Zinyakov, A. S. Pershin, I. V. Shevchenko, I. Yu. Zhukov, D. N. Fedoseyeva, D. V. Sharypova, A. S. Igolkin, N. N. Vlasova

“…In particular, no virus genes directly associated with pig virulence have been identifed. Identifcation of such genes will enable preparation of deletion mutant ASF virus strains as well as development and testing of pilot safe vaccines based on the said virus strains. …”
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Identification of site-specific adaptations conferring increased neural cell tropism during human enterovirus 71 infection. by Samuel Cordey, Tom J Petty, Manuel Schibler, Yannick Martinez, Daniel Gerlach, Sandra van Belle, Lara Turin, Evgeny Zdobnov, Laurent Kaiser, Caroline Tapparel

“…Enterovirus 71 (EV71) is one of the most virulent enteroviruses, but the specific molecular features that enhance its ability to disseminate in humans remain unknown. …”
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Results of scientific expedition to natural biotopes of the Republic of Tyva in 2019 with the purpose of infectious disease monitoring in wild bird populations by M. S. Volkov, V. N. Irza, A. V. Varkentin, S. V. Rogolyov, A. V. Andriyasov

“…Notwithstanding the absence of AIV very virulent isolate detections in wild bird populations the middle term prognosis for 2020 can be designated as cautious, as the avian influenza epidemic situation is deteriorating globally, especially in the European countries, and the threat of the virus introduction to the Russian territory with migratory birds still exists.…”
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