Stress contingent changes in Hog1 pathway architecture and regulation in Candida albicans. by Alison M Day, Min Cao, Alessandra da Silva Dantas, Olga Ianieva, Carmen Herrero-de-Dios, Alistair J P Brown, Janet Quinn

“…The Hog1 stress-activated protein kinase (SAPK) is a key mediator of stress resistance and virulence in Candida albicans. Hog1 activation via phosphorylation of the canonical TGY motif is mediated by the Pbs2 MAPKK, which itself is activated by the Ssk2 MAPKKK. …”
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Emergence of Fusarium incarnatum and Fusarium avenaceum in wilt affected solanaceous crops of the Northern Himalayas by Tasmeen J. Parihar, Madeeha Naik, Shafqat Mehraj, Syed Inam ul Haq, Maqsooda Perveen, Ishfaq Ahmed Malla, Taniya Abid, Nadia Gul, Khalid Z. Masoodi

“…Pathogenicity tests confirmed the virulence of these pathogens, with typical wilt symptoms observed upon inoculation. …”
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Exposure of Mycobacteriodes abscessus clones to mucin affects bacterial phenotype by Amy Leestemaker-Palmer, Tiffany Ong, Luiz E Bermudez

“…These observations have direct implications in virulence and the response of the pathogen to treatment.…”
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Association between microplastics and the functionalities of human gut microbiome by Bei Gao, Lixia Chen, Lizhi Wu, Shirui Zhang, Sunan Zhao, Zhe Mo, Zhijian Chen, Pengcheng Tu

“…Associations were found between microplastics and microbial species, as well as microbial genes encoding invasion-related virulence factors, quorum sensing, autoinducer and transporter system, and microplastic biodegradation enzymes. …”
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Persistent Cutibacterium (Formerly Propionibacterium) acnes Bacteremia and Refractory Endocarditis in a Patient with Retained Implantable Pacemaker Leads by M. Freedman, J. O. Aflatooni, R. Foster, P. G. Haggerty, C. J. Derber

“…Cutibacterium (formerly Propionibacterium) acnes (C. acnes) is a commensal bacteria commonly found on the human skin and in the mouth. While the virulence of C. acnes is low in humans, it does produce a biofilm and has been identified as an etiologic agent in a growing number of implant-associated infections. …”
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Helicobacter pylori CagA promotes gastric cancer immune escape by upregulating SQLE by Sifan Liu, Nan Zhang, Xu Ji, Shuyue Yang, Zheng Zhao, Peng Li

“…Abstract Helicobacter pylori (H. pylori) infection is a well-established risk factor for gastric cancer, primarily due to its virulence factor, cytotoxin-associated gene A (CagA). …”
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Synthesis and Evaluation of In Vitro Antibacterial and Antitumor Activities of Novel N,N-Disubstituted Schiff Bases by Heng Luo, Yu-fen Xia, Bao-fei Sun, Li-rong Huang, Xing-hui Wang, Hua-yong Lou, Xu-hui Zhu, Wei-dong Pan, Xiao-dong Zhang

“…Moreover, we observed that the antibacterial action of 1a might be associated with the regulation of the expression of key virulence genes in S. aureus. Compound 1c resulted in a strong apoptotic activity against leukemia cells, also affecting the cell cycle distribution. …”
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Combining Microarray Technology and Molecular Epidemiology to Identify Genes Associated with Invasive Group B Streptococcus by Lixin Zhang, Usha Reddi, Usha Srinivasan, Sheng Li, Stephanie M. Borchardt, Parvathy Pillai, Puja Mehta, Anne N. Styka, Joan DeBusscher, Carl F. Marrs, Betsy Foxman

“…Many bacterial species function as both commensals and pathogens; we used this dual nature to develop a high-throughput molecular epidemiological approach to identifying bacterial virulence genes. We applied our approach to Group B Streptococcus (GBS). …”
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Application of Biofire Filmarray Joint Infection Panel for Rapid Identification of Aetiology in a Necrotizing Fasciitis Case by Zoltán Tóth, Bence Balázs, Walter P. Pfliegler, Eszter Csoma, László Majoros, Dorka Szűcs, Renátó Kovács

“…Based on the WGS data, the isolate belonged to the K1-capsule-type ST23, harboured a pNTUH-2044-like plasmid, and was positive for all the virulence factors associated with this lineage. The conventional susceptibility results were also in accordance with the BFJIP results; the isolate lacked any of these acquired resistance mechanisms. …”
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Exception to the Rule: Genomic Characterization of Naturally Occurring Unusual Vibrio cholerae Strains with a Single Chromosome by Gary Xie, Shannon L. Johnson, Karen W. Davenport, Mathumathi Rajavel, Torsten Waldminghaus, John C. Detter, Patrick S. Chain, Shanmuga Sozhamannan

“…Many of the known cholera virulence factors are absent. The two origins of replication and associated genes are generally intact with synonymous mutations in some genes, as are recA and mismatch repair (MMR) genes dam, mutH, and mutL; MutS function is probably impaired in NSCV2. …”
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FeLV-induced feline leukemia as a natural model for leukemia pathophysiology study (review) by T. V. Tabakaeva, A. V. Tsybulsky, K. A. Baranchugova, I. V. Galkina, M. Yu. Shchelkanov

“…Leukemia clinical man ifestations in felids depend on high virulence of the virus and the disease is characterized with pronounced clinical picture and multipleorgan dysfunction. …”
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Natural products based on Correa's cascade for the treatment of gastric cancer trilogy: Current status and future perspective by Wenhao Liao, Jing Wang, Yuchen Li

“…In phase I, NPs modulate Helicobacter pylori urease activity, motility, adhesion, virulence factors, and drug resistance, thereby inhibiting H. pylori-induced gastric mucosal inflammation and oxidative stress, and facilitating ulcer healing. …”
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Entamoeba histolytica: Gene Expression Analysis of Cells Invading Tissues by Helen C. Fernandes, Ana F. Costa, Michelle A. R. Freitas, Almir S. Martins, Jorge L. Pesquero, Élida M. Rabelo, Maria A. Gomes

“…Due to the existence of different clinical forms caused by the parasite and also different virulence levels presented by one strain, one would expect differences in the profile of gene transcripts between virulent and nonvirulent cultures. …”
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Isolation, characterization and therapeutic efficacy of lytic bacteriophage ZK22 against Salmonella Typhimurium in mice by Yihong Sun, Qing Qu, Yanhua Huang, Shuo Zhou, Hua Xiang, Wei Wang

“…A total of 78 coding sequences were predicted, with no virulence genes or drug resistance genes predicted. …”
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Dual RNA sequencing of a co-culture model of Pseudomonas aeruginosa and human 2D upper airway organoids by Cayetano Pleguezuelos-Manzano, Wouter A. G. Beenker, Gijs J. F. van Son, Harry Begthel, Gimano D. Amatngalim, Jeffrey M. Beekman, Hans Clevers, Jeroen den Hertog

“…Bacterial quorum sensing (QS) coordinates virulence factor expression and biofilm formation at population level. …”
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The Genetic Structure of Wild Orobanche cumana Wallr. (Orobanchaceae) Populations in Eastern Bulgaria Reflects Introgressions from Weedy Populations by Rocío Pineda-Martos, Antonio J. Pujadas-Salvà, José M. Fernández-Martínez, Kiril Stoyanov, Leonardo Velasco, Begoña Pérez-Vich

“…The objective of this research was to investigate genetic diversity, population structure, and virulence on sunflower of O. cumana populations parasitizing wild plants in eastern Bulgaria. …”
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Retrospective Use of Whole-Genome Sequencing Expands the Multicountry Outbreak Cluster of Listeria monocytogenes ST1247 by Mihkel Mäesaar, Rafael Mamede, Terje Elias, Mati Roasto

“…It was concluded that the persistent nature of the multicountry outbreak-related L. monocytogenes strain VLTRLM2013 together with stress island, virulence, and antibiotic resistance genes could potentially be the determining factors for the extensive and prolonged outbreak affecting five European Union countries. …”
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Molecular detection of <i>Streptococcus agalactiae</i> in pregnant women and percentage of vertical transmission to their neonates in Babylon province by Ali D. Marhash, Zainab N. Nabat, Nawras A. Abbas

“…The objective of the study is the isolation and molecular detection of virulence gene of S. agalactiae group B (GBS), and evaluation of the percentage of mother-to-child transmission of the pathogen. …”
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Occurrence and Antimicrobial Resistance Pattern of Listeria monocytogenes Isolated From Bovine’s Milk and Meat in Mekelle City, Ethiopia by Tesfay Hailu, Getachew Gugsa, Yisehak Tsegaye, Meselu Ahmed, Nesibu Awol

“…Listeria monocytogenes is an opportunistic and emerging foodborne zoonotic pathogen that encompasses a diversity of strains with varied virulence and can cause serious human and animal infections worldwide. …”
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Genomic insights into the probiotic potential and genes linked to gallic acid metabolism in Pediococcus pentosaceus MBBL6 isolated from healthy cow milk. by Md Morshedur Rahman, Naim Siddique, Soharth Hasnat, Md Tanvir Rahman, Mustafizur Rahman, Munirul Alam, Ziban Chandra Das, Tofazzal Islam, M Nazmul Hoque

“…The safety assessment of MBBL6 genome revealed no virulence genes and a low pathogenicity score (0.196 out of 1.0). …”
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